Protein: WDR12
Ribosome biogenesis protein WDR12 (WD repeat-containing protein 12)

Gene: WDR12
Organism: Homo sapiens
Interactions: 96
UniProt ID: Q9GZL7

Gene Ontology (top 5):
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0007219 - Notch signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1048903

BOP1
Ribosome biogenesis protein BOP1

6

20

Small-scale

0.943

High

1325949

WDR55
WD repeat-containing protein 55

2

17

High-throughput

0.811

High

1325951

ANLN
Anillin

2

4

High-throughput

0.754

High

132213

PESC
Pescadillo homolog

9

4

Small-scale

0.754

High

1085937

IF16
Gamma-interferon-inducible protein 16

3

7

High-throughput

0.656

High

271406

NPM3
Nucleoplasmin-3

2

8

High-throughput

0.628

High

418636

NPM
Nucleophosmin

2

8

High-throughput

0.628

High

934458

CSK21
Casein kinase II subunit alpha

2

13

High-throughput

0.628

High

182894

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.618

High

714580

GRK5
G protein-coupled receptor kinase 5

1

10

High-throughput

0.618

High

903500

WDR5
WD repeat-containing protein 5

1

18

Small-scale

0.618

High

1224155

KMT2E
Inactive histone-lysine N-methyltransferase 2E

1

15

Small-scale

0.618

High

1325947

WDR12
Ribosome biogenesis protein WDR12

1

17

Small-scale

0.618

High

1325955

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

8

High-throughput

0.618

High

1325959

FBW1A
F-box/WD repeat-containing protein 1A

1

16

High-throughput

0.618

High

1292652

DDX27
Probable ATP-dependent RNA helicase DDX27

2

20

Small-scale

0.611

High

1316864

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

2

15

High-throughput

0.611

High

159734

CASQ2
Calsequestrin-2

3

9

High-throughput

0.609

High

370391

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1174298

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.557

High

149263

CTRO
Citron Rho-interacting kinase

1

8

High-throughput

0.553

High

1171614

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.553

High

1325948

PKHA4
Pleckstrin homology domain-containing family A member 4

1

19

High-throughput

0.553

High

1325957

FBW1B
F-box/WD repeat-containing protein 11

1

16

High-throughput

0.553

High

176272

PPM1G
Protein phosphatase 1G

1

2

High-throughput

0.536

High

269871

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

19

High-throughput

0.536

High

586967

CSK22
Casein kinase II subunit alpha'

1

9

High-throughput

0.536

High

642578

RL13
Large ribosomal subunit protein eL13

1

4

High-throughput

0.536

High

758130

SMBP2
DNA-binding protein SMUBP-2

1

9

High-throughput

0.536

High

781814

MNDA
Myeloid cell nuclear differentiation antigen

1

7

High-throughput

0.536

High

942933

SRPK2
SRSF protein kinase 2

1

20

High-throughput

0.536

High

1028809

SRSF5
Serine/arginine-rich splicing factor 5

1

19

High-throughput

0.536

High

1040677

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.536

High

1150355

RL7L
Ribosomal protein uL30-like

1

9

High-throughput

0.536

High

1325954

LYAR
Cell growth-regulating nucleolar protein

1

3

High-throughput

0.536

High

1325960

RL36
Large ribosomal subunit protein eL36

1

3

High-throughput

0.536

High

228624

PRKN
E3 ubiquitin-protein ligase parkin

2

19

High-throughput

0.533

High

1025955

TADBP
TAR DNA-binding protein 43

1

20

High-throughput

0.515

High

1264652

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.513

High

1291184

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

559929

H12
Histone H1.2

1

12

Small-scale

0.512

High

772150

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.493

High

489262

H14
Histone H1.4

1

12

High-throughput

0.489

High

559485

H13
Histone H1.3

1

12

High-throughput

0.489

High

806670

RL28
Large ribosomal subunit protein eL28

1

2

High-throughput

0.489

High

1201059

PNM8A
Paraneoplastic antigen-like protein 8A

1

1

High-throughput

0.489

High

1325956

IL17B
Interleukin-17B

1

1

High-throughput

0.489

High

122986

MEN1
Menin

1

4

High-throughput

0.479

High

210262

PRC1
Protein regulator of cytokinesis 1

1

8

High-throughput

0.479

High

244909

BRD4
Bromodomain-containing protein 4

1

16

High-throughput

0.479

High

258184

DNJB6
DnaJ homolog subfamily B member 6

1

13

High-throughput

0.479

High

347840

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

387465

P53
Cellular tumor antigen p53

1

6

High-throughput

0.479

High

442477

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

16

High-throughput

0.479

High

553653

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

598311

FLNA
Filamin-A

1

14

High-throughput

0.479

High

652185

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

718176

BMI1
Polycomb complex protein BMI-1

1

18

High-throughput

0.479

High

721383

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

760293

RL3
Large ribosomal subunit protein uL3

1

8

High-throughput

0.479

High

780065

CCNF
Cyclin-F

1

9

High-throughput

0.479

High

824363

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

11

High-throughput

0.479

High

877875

FOXA1
Hepatocyte nuclear factor 3-alpha

1

14

High-throughput

0.479

High

916840

RS6
Small ribosomal subunit protein eS6

1

4

High-throughput

0.479

High

935213

H31
Histone H3.1

1

9

High-throughput

0.479

High

969974

KIF23
Kinesin-like protein KIF23

1

9

High-throughput

0.479

High

1036055

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

1153918

IFIX
Pyrin and HIN domain-containing protein 1

1

7

High-throughput

0.479

High

1256381

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

1264183

DNJC9
DnaJ homolog subfamily C member 9

1

16

High-throughput

0.479

High

1269555

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1287371

OPTN
Optineurin

1

20

High-throughput

0.479

High

1293979

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.479

High

1304091

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

1325950

BRD7
Bromodomain-containing protein 7

1

16

High-throughput

0.479

High

1325952

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

4

High-throughput

0.479

High

1325953

MDN1
Midasin

1

15

Small-scale

0.479

High

1285754

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1043567

CUL4B
Cullin-4B

1

20

High-throughput

0.445

High

1057638

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

9

High-throughput

0.445

High

101160

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

256050

OBSL1
Obscurin-like protein 1

1

9

High-throughput

0.437

High

323105

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

19

High-throughput

0.437

High

374842

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.437

High

391890

H2A1B
Histone H2A type 1-B/E

1

9

High-throughput

0.437

High

685012

STIP1
Stress-induced-phosphoprotein 1

1

12

High-throughput

0.437

High

1066655

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.437

High

1101456

BLTP1
Bridge-like lipid transfer protein family member 1

1

2

High-throughput

0.437

High

1199408

LYRIC
Protein LYRIC

1

4

Small-scale

0.437

High

1201656

ZCH18
Zinc finger CCCH domain-containing protein 18

1

20

High-throughput

0.437

High

1286691

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.437

High

1325958

HECD1
E3 ubiquitin-protein ligase HECTD1

1

14

High-throughput

0.437

High

1130562

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

10

High-throughput

0.407

High

1236256

TMC5A
Transmembrane and coiled-coil domain-containing protein 5A

1

0

High-throughput

0.269

Low

1243923

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024