Protein: I2BPL
Probable E3 ubiquitin-protein ligase IRF2BPL (EC 2.3.2.27) (Enhanced at puberty protein 1) (Interferon regulatory factor 2-binding protein-like)

Gene: I2BPL, IRF2BPL
Organism: Homo sapiens
Interactions: 33
UniProt ID: Q9H1B7

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

536551

IRF2
Interferon regulatory factor 2

4

5

High-throughput

0.704

High

548332

FOSL2
Fos-related antigen 2

3

7

High-throughput

0.667

High

1048844

VGLL4
Transcription cofactor vestigial-like protein 4

3

2

High-throughput

0.667

High

1215913

I2BP1
Interferon regulatory factor 2-binding protein 1

3

7

Small-scale

0.667

High

1191146

I2BP2
Interferon regulatory factor 2-binding protein 2

3

7

Small-scale

0.640

High

487754

ANDR
Androgen receptor

2

20

Small-scale

0.584

High

717340

CTNB1
Catenin beta-1

2

7

Small-scale

0.584

High

801368

KI67
Proliferation marker protein Ki-67

1

7

High-throughput

0.536

High

1050055

SCRIB
Protein scribble homolog

1

7

High-throughput

0.536

High

1192664

UB2Q1
Ubiquitin-conjugating enzyme E2 Q1

1

0

High-throughput

0.518

High

653160

DCK
Deoxycytidine kinase

1

0

High-throughput

0.513

High

1306578

TS101
Tumor susceptibility gene 101 protein

1

1

High-throughput

0.501

High

324025

BAG2
BAG family molecular chaperone regulator 2

1

3

High-throughput

0.489

High

1235369

KCD17
BTB/POZ domain-containing protein KCTD17

1

4

High-throughput

0.489

High

122995

MEN1
Menin

1

2

High-throughput

0.479

High

244923

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.479

High

504739

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

570059

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.479

High

727802

SOX5
Transcription factor SOX-5

1

18

High-throughput

0.479

High

727922

SOX6
Transcription factor SOX-6

1

18

High-throughput

0.479

High

799148

NKX21
Homeobox protein Nkx-2.1

1

14

High-throughput

0.479

High

1024879

KLF10
Krueppel-like factor 10

1

3

High-throughput

0.479

High

1042514

CUL3
Cullin-3

1

4

High-throughput

0.479

High

1054581

RBM39
RNA-binding protein 39

1

6

Small-scale

0.479

High

1269582

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1328578

I2BPL
Probable E3 ubiquitin-protein ligase IRF2BPL

1

14

Small-scale

0.479

High

1328579

TBK1
Serine/threonine-protein kinase TBK1

1

2

High-throughput

0.479

High

500102

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

1241773

RN169
E3 ubiquitin-protein ligase RNF169

1

1

Small-scale

0.445

High

101170

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

385496

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.437

High

1171659

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.437

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024