Protein: ADPPT
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (EC 2.7.8.7) (4'-phosphopantetheinyl transferase) (Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase) (AASD-PPT) (LYS5 ortholog)

Gene: ADPPT, AASDHPPT
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q9NRN7

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0005829 - cytosol
GO:0008897 - holo-[acyl-carrier-protein] synthase activity
GO:0009258 - 10-formyltetrahydrofolate catabolic process
GO:0015939 - pantothenate metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1020951

TRAF2
TNF receptor-associated factor 2

4

0

High-throughput

0.675

High

474853

POTEI
POTE ankyrin domain family member I

3

2

High-throughput

0.667

High

1344994

PPR3C
Protein phosphatase 1 regulatory subunit 3C

2

0

High-throughput

0.602

High

228817

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

981102

LGUL
Lactoylglutathione lyase

2

0

High-throughput

0.559

High

1074423

STIL
SCL-interrupting locus protein

2

0

High-throughput

0.559

High

1216719

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

0

High-throughput

0.549

High

336605

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

568805

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.513

High

1030505

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

1219040

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1336349

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.513

High

780168

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

1344989

BABA1
BRISC and BRCA1-A complex member 1

1

0

High-throughput

0.493

High

1344992

GT2D1
General transcription factor II-I repeat domain-containing protein 1

1

0

High-throughput

0.493

High

160801

AURKA
Aurora kinase A

1

1

High-throughput

0.479

High

892059

ACTB
Actin, cytoplasmic 1

1

2

High-throughput

0.479

High

354574

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

601383

VDAC1
Voltage-dependent anion-selective channel protein 1

1

0

High-throughput

0.458

High

909186

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

961285

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1200686

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1241428

MTMRE
Myotubularin-related protein 14

1

0

High-throughput

0.458

High

1332658

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1335499

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

1344566

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

1344988

PHP14
14 kDa phosphohistidine phosphatase

1

0

High-throughput

0.458

High

1344990

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

1344991

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1153403

PKHA7
Pleckstrin homology domain-containing family A member 7

1

1

High-throughput

0.445

High

553822

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

1026551

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.437

High

378183

PRIO
Major prion protein

1

0

High-throughput

0.426

High

497648

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

1130631

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1222592

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.426

High

1223634

ULK2
Serine/threonine-protein kinase ULK2

1

0

High-throughput

0.426

High

1344993

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

7

0

High-throughput

0.391

High

1316138

ANGL4
Angiopoietin-related protein 4

2

0

High-throughput

0.328

High

197836

CRX
Cone-rod homeobox protein

2

0

High-throughput

0.316

High

1127594

EFHC2
EF-hand domain-containing family member C2

2

0

High-throughput

0.316

High

1306263

MDFI
MyoD family inhibitor

1

0

High-throughput

0.282

High

452895

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1121804

ANR39
Ankyrin repeat domain-containing protein 39

1

0

High-throughput

0.279

Low

1168205

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

1221403

T183A
Transmembrane protein 183A

1

0

High-throughput

0.279

Low

1262122

SEN15
tRNA-splicing endonuclease subunit Sen15

1

0

High-throughput

0.279

Low

101213

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

239620

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.249

Low

242901

TRI13
E3 ubiquitin-protein ligase TRIM13

1

0

High-throughput

0.249

Low

262595

TULP3
Tubby-related protein 3

1

0

High-throughput

0.249

Low

295295

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.249

Low

385578

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

652355

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

721546

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

824420

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

1171880

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1173250

PAXI1
PAX-interacting protein 1

1

0

High-throughput

0.249

Low

1199322

MARH3
E3 ubiquitin-protein ligase MARCHF3

1

0

High-throughput

0.249

Low

402520

JUN
Transcription factor Jun

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024