Protein: TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)

Gene: TAB2
Organism: Homo sapiens
Interactions: 192
UniProt ID: Q9NYJ8

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

476477

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

16

10

Small-scale

0.986

High

201449

M3K7
Mitogen-activated protein kinase kinase kinase 7

45

4

Small-scale

0.771

High

1348535

TRAF6
TNF receptor-associated factor 6

19

17

Small-scale

0.765

High

1077967

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

16

1

Small-scale

0.764

High

848497

IRAK1
Interleukin-1 receptor-associated kinase 1

8

1

Small-scale

0.747

High

352712

TNFA
Tumor necrosis factor

5

3

Small-scale

0.702

High

1348537

EMIL1
EMILIN-1

4

12

High-throughput

0.698

High

1020961

TRAF2
TNF receptor-associated factor 2

4

15

Small-scale

0.687

High

1038329

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

4

14

Small-scale

0.687

High

370578

ESR1
Estrogen receptor

3

20

Small-scale

0.678

High

548268

FOSL1
Fos-related antigen 1

3

9

High-throughput

0.667

High

905185

1433G
14-3-3 protein gamma

3

20

High-throughput

0.667

High

982553

1433F
14-3-3 protein eta

3

20

High-throughput

0.667

High

1173366

RFPLB
Ret finger protein-like 4B

3

8

High-throughput

0.667

High

1348532

CARD8
Caspase recruitment domain-containing protein 8

3

1

High-throughput

0.667

High

1348529

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

3

1

High-throughput

0.665

High

1234344

TAB3
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3

3

14

Small-scale

0.662

High

1348539

NEMO
NF-kappa-B essential modulator

3

7

Small-scale

0.661

High

1348521

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

3

14

Small-scale

0.661

High

1054218

BECN1
Beclin-1

2

2

Small-scale

0.649

High

1348541

NUMBL
Numb-like protein

2

4

Small-scale

0.642

High

261598

NCOR1
Nuclear receptor corepressor 1

2

17

Small-scale

0.639

High

1233655

CARME
Carnosine N-methyltransferase

3

0

High-throughput

0.638

High

1333887

TRI45
E3 ubiquitin-protein ligase TRIM45

2

20

Small-scale

0.634

High

398114

ISG15
Ubiquitin-like protein ISG15

1

10

Small-scale

0.618

High

475212

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

10

High-throughput

0.618

High

443848

VIME
Vimentin

2

6

High-throughput

0.614

High

927590

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.614

High

432309

HS90A
Heat shock protein HSP 90-alpha

2

6

Small-scale

0.611

High

1268952

AKAP1
A-kinase anchor protein 1, mitochondrial

2

1

High-throughput

0.611

High

419064

TPM3
Tropomyosin alpha-3 chain

2

1

High-throughput

0.606

High

943703

KRT85
Keratin, type II cuticular Hb5

2

1

High-throughput

0.606

High

1230733

VPS52
Vacuolar protein sorting-associated protein 52 homolog

2

1

High-throughput

0.606

High

395920

A4
Amyloid-beta precursor protein

2

1

High-throughput

0.602

High

1015822

SCRN1
Secernin-1

2

0

High-throughput

0.602

High

1239080

I17RC
Interleukin-17 receptor C

2

0

High-throughput

0.602

High

1348523

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

2

5

Small-scale

0.601

High

324082

BAG2
BAG family molecular chaperone regulator 2

2

0

High-throughput

0.585

High

135043

TRI38
E3 ubiquitin-protein ligase TRIM38

2

11

Small-scale

0.584

High

487798

ANDR
Androgen receptor

2

20

Small-scale

0.584

High

653104

CD82
CD82 antigen

2

1

Small-scale

0.584

High

824461

NR2C2
Nuclear receptor subfamily 2 group C member 2

2

16

Small-scale

0.584

High

910093

1433E
14-3-3 protein epsilon

2

5

High-throughput

0.584

High

941511

RNF4
E3 ubiquitin-protein ligase RNF4

2

2

Small-scale

0.584

High

1146898

A16L1
Autophagy-related protein 16-1

2

6

High-throughput

0.584

High

1343343

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

2

4

Small-scale

0.584

High

253213

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

856046

ZN143
Zinc finger protein 143

2

0

High-throughput

0.580

High

587727

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

10

Small-scale

0.578

High

1290459

DC2I2
Cytoplasmic dynein 2 intermediate chain 2

1

13

Small-scale

0.573

High

177391

HDAC3
Histone deacetylase 3

1

14

Small-scale

0.561

High

1329421

PPIL3
Peptidyl-prolyl cis-trans isomerase-like 3

1

3

Small-scale

0.561

High

1348522

NLK
Serine/threonine-protein kinase NLK

1

3

Small-scale

0.561

High

1348525

TNIK
TRAF2 and NCK-interacting protein kinase

1

5

Small-scale

0.554

High

1071021

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

11

Small-scale

0.552

High

1299768

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

7

High-throughput

0.552

High

984036

ZBT16
Zinc finger and BTB domain-containing protein 16

1

0

High-throughput

0.549

High

915293

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

2

High-throughput

0.541

High

1264813

TITIN
Titin

1

6

High-throughput

0.541

High

1012525

HSP7E
Heat shock 70 kDa protein 14

1

6

High-throughput

0.536

High

1147895

C102B
Coiled-coil domain-containing protein 102B

1

2

High-throughput

0.536

High

1326696

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

3

High-throughput

0.536

High

1327709

SHRPN
Sharpin

1

2

High-throughput

0.536

High

1348025

ANR10
Ankyrin repeat domain-containing protein 10

1

5

High-throughput

0.536

High

1159458

FBX42
F-box only protein 42

2

3

Small-scale

0.533

High

167403

SMAD7
Mothers against decapentaplegic homolog 7

1

4

Small-scale

0.529

High

1263124

EDAD
Ectodysplasin-A receptor-associated adapter protein

1

0

Small-scale

0.529

High

602880

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

0

High-throughput

0.518

High

942267

GTF2I
General transcription factor II-I

1

0

High-throughput

0.518

High

1318445

S19A3
Thiamine transporter 2

1

0

High-throughput

0.518

High

201830

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

3

Small-scale

0.515

High

957790

XIAP
E3 ubiquitin-protein ligase XIAP

1

4

Small-scale

0.515

High

1317090

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

9

Small-scale

0.515

High

1348540

TNR11
Tumor necrosis factor receptor superfamily member 11A

1

5

Small-scale

0.515

High

995260

GOGA2
Golgin subfamily A member 2

1

2

High-throughput

0.515

High

515959

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.513

High

886023

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

1

0

High-throughput

0.513

High

1298729

TMM74
Transmembrane protein 74

1

0

High-throughput

0.513

High

1348536

PCDGE
Protocadherin gamma-B2

1

0

High-throughput

0.513

High

1348538

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.513

High

158554

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

6

Small-scale

0.501

High

245642

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

8

Small-scale

0.501

High

1038759

HDAC1
Histone deacetylase 1

1

14

Small-scale

0.501

High

1348528

HDAC5
Histone deacetylase 5

1

19

Small-scale

0.501

High

1345798

ZF64B
Zinc finger protein 64

1

0

High-throughput

0.493

High

935967

NOMO3
BOS complex subunit NOMO3

1

1

High-throughput

0.489

High

1190159

PK1L2
Polycystin-1-like protein 2

1

2

High-throughput

0.489

High

363326

FINC
Fibronectin

1

3

High-throughput

0.481

High

930421

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.480

High

135510

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

4

Small-scale

0.479

High

163382

XPO1
Exportin-1

1

7

High-throughput

0.479

High

167625

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

7

Small-scale

0.479

High

179965

TLR3
Toll-like receptor 3

1

3

Small-scale

0.479

High

255205

ATG13
Autophagy-related protein 13

1

2

Small-scale

0.479

High

326795

SNAI1
Zinc finger protein SNAI1

1

3

High-throughput

0.479

High

328667

MBD3
Methyl-CpG-binding domain protein 3

1

3

Small-scale

0.479

High

377742

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

381315

TBB4A
Tubulin beta-4A chain

1

1

High-throughput

0.479

High

418733

NPM
Nucleophosmin

1

2

High-throughput

0.479

High

428472

TBB5
Tubulin beta chain

1

1

High-throughput

0.479

High

451578

CLCA
Clathrin light chain A

1

2

High-throughput

0.479

High

502614

BIP
Endoplasmic reticulum chaperone BiP

1

7

High-throughput

0.479

High

504866

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

537101

TRI27
Zinc finger protein RFP

1

11

Small-scale

0.479

High

553902

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.479

High

583608

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

584486

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

5

Small-scale

0.479

High

598350

FLNA
Filamin-A

1

2

High-throughput

0.479

High

639654

TNR5
Tumor necrosis factor receptor superfamily member 5

1

6

Small-scale

0.479

High

647327

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

653396

PYR1
Multifunctional protein CAD

1

1

High-throughput

0.479

High

665671

EPHB2
Ephrin type-B receptor 2

1

3

Small-scale

0.479

High

681630

DNJA1
DnaJ homolog subfamily A member 1

1

2

High-throughput

0.479

High

683009

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

6

High-throughput

0.479

High

684358

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

751863

GRP75
Stress-70 protein, mitochondrial

1

10

High-throughput

0.479

High

781998

PERI
Peripherin

1

6

High-throughput

0.479

High

783329

M3K8
Mitogen-activated protein kinase kinase kinase 8

1

1

Small-scale

0.479

High

788931

RS27
Small ribosomal subunit protein eS27

1

1

High-throughput

0.479

High

832741

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.479

High

870911

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

2

Small-scale

0.479

High

871808

HSP72
Heat shock-related 70 kDa protein 2

1

4

High-throughput

0.479

High

878260

SEC13
Protein SEC13 homolog

1

10

High-throughput

0.479

High

883237

SIK1
Serine/threonine-protein kinase SIK1

1

3

Small-scale

0.479

High

886385

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

4

Small-scale

0.479

High

896236

UBC12
NEDD8-conjugating enzyme Ubc12

1

1

High-throughput

0.479

High

919538

RL23
Large ribosomal subunit protein uL14

1

1

High-throughput

0.479

High

930027

ACTG
Actin, cytoplasmic 2

1

19

High-throughput

0.479

High

960997

CLH1
Clathrin heavy chain 1

1

1

High-throughput

0.479

High

968500

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

11

High-throughput

0.479

High

984454

EF1A2
Elongation factor 1-alpha 2

1

2

High-throughput

0.479

High

1026560

RFA4
Replication protein A 30 kDa subunit

1

6

High-throughput

0.479

High

1036949

SQSTM
Sequestosome-1

1

5

High-throughput

0.479

High

1045549

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

4

High-throughput

0.479

High

1048809

TRI29
Tripartite motif-containing protein 29

1

15

Small-scale

0.479

High

1052785

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

20

Small-scale

0.479

High

1080802

ZYX
Zyxin

1

3

High-throughput

0.479

High

1082646

MK14
Mitogen-activated protein kinase 14

1

2

Small-scale

0.479

High

1085081

DREB
Drebrin

1

4

High-throughput

0.479

High

1114378

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

3

High-throughput

0.479

High

1148245

RNF43
E3 ubiquitin-protein ligase RNF43

1

3

High-throughput

0.479

High

1168712

SYNE3
Nesprin-3

1

5

High-throughput

0.479

High

1206076

MIB1
E3 ubiquitin-protein ligase MIB1

1

4

High-throughput

0.479

High

1223392

TRI22
E3 ubiquitin-protein ligase TRIM22

1

10

Small-scale

0.479

High

1230188

CNTRB
Centrobin

1

4

High-throughput

0.479

High

1254286

BICD2
Protein bicaudal D homolog 2

1

14

High-throughput

0.479

High

1267195

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

1269776

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1270957

KAT6A
Histone acetyltransferase KAT6A

1

20

High-throughput

0.479

High

1290081

RNF31
E3 ubiquitin-protein ligase RNF31

1

10

High-throughput

0.479

High

1291720

BICD1
Protein bicaudal D homolog 1

1

9

High-throughput

0.479

High

1296931

SNX27
Sorting nexin-27

1

13

High-throughput

0.479

High

1302457

SIN3A
Paired amphipathic helix protein Sin3a

1

4

Small-scale

0.479

High

1304826

TBX5
T-box transcription factor TBX5

1

11

High-throughput

0.479

High

1307021

ANM1
Protein arginine N-methyltransferase 1

1

7

High-throughput

0.479

High

1318181

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

1

8

Small-scale

0.479

High

1318714

TRIM5
Tripartite motif-containing protein 5

1

10

Small-scale

0.479

High

1332691

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

1344035

PDLI7
PDZ and LIM domain protein 7

1

3

Small-scale

0.479

High

1348524

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

1348526

UBP18
Ubl carboxyl-terminal hydrolase 18

1

4

Small-scale

0.479

High

1348527

Q9UQC1
Heat shock protein 72

1

6

High-throughput

0.479

High

1348530

RUVB2
RuvB-like 2

1

5

High-throughput

0.479

High

1348531

RUVB1
RuvB-like 1

1

5

High-throughput

0.479

High

1348533

SIK3
Serine/threonine-protein kinase SIK3

1

3

Small-scale

0.479

High

1348534

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

3

Small-scale

0.479

High

1348542

PIAS3
E3 SUMO-protein ligase PIAS3

1

2

Small-scale

0.479

High

571783

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

0

High-throughput

0.458

High

626847

PAR1
Proteinase-activated receptor 1

1

0

Small-scale

0.458

High

738585

TGFR1
TGF-beta receptor type-1

1

0

Small-scale

0.458

High

990358

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1014293

BST2
Bone marrow stromal antigen 2

1

0

Small-scale

0.458

High

1222708

TM192
Transmembrane protein 192

1

0

High-throughput

0.458

High

1230553

CCAR2
Cell cycle and apoptosis regulator protein 2

1

0

High-throughput

0.458

High

1271774

TANK
TRAF family member-associated NF-kappa-B activator

1

0

Small-scale

0.458

High

1284656

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.458

High

1306068

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

1

0

Small-scale

0.458

High

497686

TAU
Microtubule-associated protein tau

1

13

High-throughput

0.445

High

1032651

CTBP1
C-terminal-binding protein 1

1

3

High-throughput

0.445

High

1301400

NUDC1
NudC domain-containing protein 1

1

1

High-throughput

0.445

High

517499

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.438

High

1346341

EXOC1
Exocyst complex component 1

1

0

High-throughput

0.438

High

101233

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

1268019

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

1

High-throughput

0.437

High

1333640

MANS1
MANSC domain-containing protein 1

2

0

High-throughput

0.328

High

1255328

MIPT3
TRAF3-interacting protein 1

2

0

High-throughput

0.307

High

1331069

CST9L
Cystatin-9-like

1

0

High-throughput

0.282

High

263005

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.269

Low

377875

TFF1
Trefoil factor 1

1

0

Small-scale

0.249

Low

995459

LG3BP
Galectin-3-binding protein

1

0

High-throughput

0.249

Low

1286546

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024