Protein: TRPS1
Zinc finger transcription factor Trps1 (Tricho-rhino-phalangeal syndrome type I protein) (Zinc finger protein GC79)

Gene: TRPS1
Organism: Homo sapiens
Interactions: 130
UniProt ID: Q9UHF7

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001501 - skeletal system development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1032667

CTBP1
C-terminal-binding protein 1

6

9

High-throughput

0.732

High

928511

DYL1
Dynein light chain 1, cytoplasmic

4

2

Small-scale

0.709

High

296168

MTA2
Metastasis-associated protein MTA2

1

20

High-throughput

0.691

High

1031969

MTA1
Metastasis-associated protein MTA1

1

20

High-throughput

0.691

High

1205832

P66A
Transcriptional repressor p66-alpha

1

10

High-throughput

0.691

High

1263991

P66B
Transcriptional repressor p66-beta

1

10

High-throughput

0.691

High

1312040

MTA3
Metastasis-associated protein MTA3

1

20

High-throughput

0.691

High

1038786

HDAC1
Histone deacetylase 1

3

20

High-throughput

0.667

High

1270506

HDAC2
Histone deacetylase 2

3

20

Small-scale

0.667

High

930439

UBC9
SUMO-conjugating enzyme UBC9

2

8

Small-scale

0.636

High

370650

ESR1
Estrogen receptor

3

20

High-throughput

0.633

High

997947

RBBP4
Histone-binding protein RBBP4

2

20

High-throughput

0.628

High

1023013

CDC16
Cell division cycle protein 16 homolog

2

5

High-throughput

0.628

High

1353977

NLK
Serine/threonine-protein kinase NLK

2

7

High-throughput

0.628

High

620437

GATA2
Endothelial transcription factor GATA-2

1

15

High-throughput

0.618

High

620588

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

15

High-throughput

0.618

High

822690

LHX1
LIM/homeobox protein Lhx1

1

15

High-throughput

0.618

High

839839

LHX2
LIM/homeobox protein Lhx2

1

18

High-throughput

0.618

High

1281197

LHX4
LIM/homeobox protein Lhx4

1

20

High-throughput

0.618

High

1354245

LHX3
LIM/homeobox protein Lhx3

1

19

High-throughput

0.618

High

1291320

DYL2
Dynein light chain 2, cytoplasmic

2

2

High-throughput

0.611

High

1354071

UXT
Protein UXT

2

0

High-throughput

0.602

High

818568

SOX2
Transcription factor SOX-2

2

20

Small-scale

0.584

High

883442

CF298
Cilia- and flagella-associated protein 298

1

1

High-throughput

0.541

High

146880

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

3

High-throughput

0.536

High

318028

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

8

High-throughput

0.536

High

328673

MBD3
Methyl-CpG-binding domain protein 3

1

9

High-throughput

0.536

High

515623

SRF
Serum response factor

1

4

High-throughput

0.536

High

647704

MK03
Mitogen-activated protein kinase 3

1

4

High-throughput

0.536

High

659080

MK01
Mitogen-activated protein kinase 1

1

4

High-throughput

0.536

High

881324

CTBP2
C-terminal-binding protein 2

1

9

High-throughput

0.536

High

989729

CDK18
Cyclin-dependent kinase 18

1

6

High-throughput

0.536

High

1018736

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.536

High

1029342

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

3

High-throughput

0.536

High

1055653

MCM6
DNA replication licensing factor MCM6

1

1

High-throughput

0.536

High

1059926

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.536

High

1075267

TEAD2
Transcriptional enhancer factor TEF-4

1

1

High-throughput

0.536

High

1080570

ZFHX3
Zinc finger homeobox protein 3

1

8

High-throughput

0.536

High

1133773

BEND3
BEN domain-containing protein 3

1

3

High-throughput

0.536

High

1349613

FOXJ2
Forkhead box protein J2

1

20

High-throughput

0.536

High

1353860

MBD2
Methyl-CpG-binding domain protein 2

1

9

High-throughput

0.536

High

941558

RNF4
E3 ubiquitin-protein ligase RNF4

1

14

Small-scale

0.534

High

165095

SC16A
Protein transport protein Sec16A

1

9

High-throughput

0.489

High

958858

EM55
55 kDa erythrocyte membrane protein

1

1

High-throughput

0.489

High

1349470

PALS2
Protein PALS2

1

1

High-throughput

0.489

High

928223

SUMO1
Small ubiquitin-related modifier 1

1

4

Small-scale

0.481

High

118618

EYA2
Eyes absent homolog 2

1

11

High-throughput

0.479

High

135172

NFIB
Nuclear factor 1 B-type

1

9

High-throughput

0.479

High

171090

TBXT
T-box transcription factor T

1

6

High-throughput

0.479

High

197850

CRX
Cone-rod homeobox protein

1

16

High-throughput

0.479

High

211990

TLX3
T-cell leukemia homeobox protein 3

1

15

High-throughput

0.479

High

225799

SOX15
Transcription factor SOX-15

1

18

High-throughput

0.479

High

232574

KDM1A
Lysine-specific histone demethylase 1A

1

16

High-throughput

0.479

High

245061

BRD4
Bromodomain-containing protein 4

1

11

High-throughput

0.479

High

271803

PRDM1
PR domain zinc finger protein 1

1

5

High-throughput

0.479

High

279820

CDKA2
Cyclin-dependent kinase 2-associated protein 2

1

3

Small-scale

0.479

High

317020

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

377786

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

443263

NFIC
Nuclear factor 1 C-type

1

11

High-throughput

0.479

High

486841

MYB
Transcriptional activator Myb

1

4

High-throughput

0.479

High

487820

ANDR
Androgen receptor

1

18

High-throughput

0.479

High

505306

EGR2
E3 SUMO-protein ligase EGR2

1

2

High-throughput

0.479

High

507523

ERG
Transcriptional regulator ERG

1

10

High-throughput

0.479

High

542081

ETS1
Protein C-ets-1

1

10

High-throughput

0.479

High

546053

MYOD1
Myoblast determination protein 1

1

8

High-throughput

0.479

High

553994

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

617387

SP100
Nuclear autoantigen Sp-100

1

17

High-throughput

0.479

High

620218

PAX7
Paired box protein Pax-7

1

20

High-throughput

0.479

High

641591

PAX6
Paired box protein Pax-6

1

12

High-throughput

0.479

High

652535

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

658573

TEAD1
Transcriptional enhancer factor TEF-1

1

1

High-throughput

0.479

High

679185

TLX1
T-cell leukemia homeobox protein 1

1

14

High-throughput

0.479

High

721711

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

727604

HNF1B
Hepatocyte nuclear factor 1-beta

1

11

High-throughput

0.479

High

727821

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.479

High

727938

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

740615

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

High-throughput

0.479

High

782685

HNF4A
Hepatocyte nuclear factor 4-alpha

1

15

High-throughput

0.479

High

785419

ELK3
ETS domain-containing protein Elk-3

1

10

High-throughput

0.479

High

818845

SOX9
Transcription factor SOX-9

1

20

High-throughput

0.479

High

877937

FOXA1
Hepatocyte nuclear factor 3-alpha

1

20

High-throughput

0.479

High

878476

PAX9
Paired box protein Pax-9

1

10

High-throughput

0.479

High

881832

SOX10
Transcription factor SOX-10

1

20

High-throughput

0.479

High

882167

GSC
Homeobox protein goosecoid

1

14

High-throughput

0.479

High

884259

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

971827

HEN1
Helix-loop-helix protein 1

1

9

High-throughput

0.479

High

973890

PAX2
Paired box protein Pax-2

1

11

High-throughput

0.479

High

974688

MECOM
Histone-lysine N-methyltransferase MECOM

1

3

High-throughput

0.479

High

980900

TLE3
Transducin-like enhancer protein 3

1

20

High-throughput

0.479

High

985265

HME1
Homeobox protein engrailed-1

1

11

High-throughput

0.479

High

988816

PAX8
Paired box protein Pax-8

1

13

High-throughput

0.479

High

1018277

NFIA
Nuclear factor 1 A-type

1

12

High-throughput

0.479

High

1019159

TP53B
TP53-binding protein 1

1

3

High-throughput

0.479

High

1021265

FOXI1
Forkhead box protein I1

1

19

High-throughput

0.479

High

1021371

FOXL1
Forkhead box protein L1

1

17

High-throughput

0.479

High

1024438

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

3

Small-scale

0.479

High

1042774

CUL3
Cullin-3

1

17

High-throughput

0.479

High

1046768

KLF5
Krueppel-like factor 5

1

20

High-throughput

0.479

High

1060383

NFIX
Nuclear factor 1 X-type

1

12

High-throughput

0.479

High

1085192

TBR1
T-box brain protein 1

1

6

High-throughput

0.479

High

1254950

SP7
Transcription factor Sp7

1

14

High-throughput

0.479

High

1262835

PHIP
PH-interacting protein

1

17

High-throughput

0.479

High

1285382

PF21A
PHD finger protein 21A

1

17

High-throughput

0.479

High

1300980

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1304715

FEV
Protein FEV

1

10

High-throughput

0.479

High

1311938

SOX7
Transcription factor SOX-7

1

20

High-throughput

0.479

High

1315386

KLF16
Krueppel-like factor 16

1

19

High-throughput

0.479

High

1318658

FOXQ1
Forkhead box protein Q1

1

20

High-throughput

0.479

High

1332329

SOX17
Transcription factor SOX-17

1

20

High-throughput

0.479

High

1349419

VSX1
Visual system homeobox 1

1

13

High-throughput

0.479

High

1354396

ZMYM2
Zinc finger MYM-type protein 2

1

2

High-throughput

0.479

High

1355448

KLF15
Krueppel-like factor 15

1

19

High-throughput

0.479

High

1355449

RCOR1
REST corepressor 1

1

20

High-throughput

0.479

High

1355451

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.479

High

182945

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

314696

PARN
Poly(A)-specific ribonuclease PARN

1

0

High-throughput

0.458

High

1135158

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.458

High

1188998

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1266707

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1314417

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1355450

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

718284

BMI1
Polycomb complex protein BMI-1

1

18

High-throughput

0.445

High

1349129

GRHL1
Grainyhead-like protein 1 homolog

1

1

High-throughput

0.445

High

101258

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

1061667

CUL7
Cullin-7

1

1

High-throughput

0.437

High

1163899

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.437

High

1190528

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

0

High-throughput

0.328

High

1290951

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

1068695

PLEC
Plectin

1

0

High-throughput

0.269

Low

1296696

C170L
Cep170-like protein

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024