Protein: METK2
S-adenosylmethionine synthase isoform type-2 (AdoMet synthase 2) (EC 2.5.1.6) (Methionine adenosyltransferase 2) (MAT 2)

Gene: METK2, Mat2a
Organism: Mus musculus
Interactions: 10
UniProt ID: Q3THS6

Gene Ontology (top 5):
GO:0004478 - methionine adenosyltransferase activity
GO:0005524 - ATP binding
GO:0006556 - S-adenosylmethionine biosynthetic process
GO:0006730 - one-carbon metabolic process
GO:0034214 - protein hexamerization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1189388

M1IP1
Mid1-interacting protein 1

1

1

Small-scale

0.457

High

109307

G5E8N3
Histone-lysine N-methyltransferase SETDB1

1

1

Small-scale

0.437

High

1189386

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.437

High

1189387

MT21E
Protein-lysine methyltransferase METTL21E

1

2

High-throughput

0.437

High

548162

ITA5
Integrin alpha-5

1

0

High-throughput

0.261

Low

236518

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

0

Small-scale

0.249

Low

927746

ATX1
Ataxin-1

1

0

High-throughput

0.249

Low

1188055

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.249

Low

1189385

FACD2
Fanconi anemia group D2 protein homolog

1

0

High-throughput

0.249

Low

915567

HMGA2
High mobility group protein HMGI-C

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025