HitPredict - High confidence protein-protein interactions

Protein: SIR41
NAD-dependent protein deacylase sir-2.2 (EC 2.3.1.286) (Regulatory protein SIR2 homolog 2)

Gene: SIR41, sir-2.2
Organism: Caenorhabditis elegans
Interactions: 4
UniProt ID: Q20480

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0008270 - zinc ion binding
GO:0017136 - histone deacetylase activity, NAD-dependent
GO:0045087 - innate immune response

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
196440	PYC1 Pyruvate carboxylase 1	1	14	Small-scale	0.479	High
233846	O45430 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial	1	14	Small-scale	0.479	High
1166911	PCCA Propionyl-CoA carboxylase alpha chain, mitochondrial	1	15	Small-scale	0.479	High
109983	G5EBS4 DBC1/CARP1 catalytically inactive NUDIX hydrolase domain-containing protein	1	5	High-throughput	0.437	High

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Last updated: 11Aug2025