Protein: PYC1
Pyruvate carboxylase 1 (EC 6.4.1.1) (Pyruvic carboxylase 1) (PCB 1)

Gene: PYC1, pyc-1
Organism: Caenorhabditis elegans
Interactions: 13
UniProt ID: O17732

Gene Ontology (top 5):
GO:0004736 - pyruvate carboxylase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0006090 - pyruvate metabolic process
GO:0006094 - gluconeogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

196437

DCR1
Endoribonuclease dcr-1

1

1

Small-scale

0.536

High

145617

CDC37
Probable Hsp90 co-chaperone cdc37

1

1

High-throughput

0.494

High

196440

SIR41
NAD-dependent protein deacylase sir-2.2

1

14

Small-scale

0.479

High

196441

SIR42
NAD-dependent protein deacylase sir-2.3

1

14

Small-scale

0.479

High

196444

MBK1
Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1

1

3

High-throughput

0.479

High

109814

G5EBS4
DBC1/CARP1 catalytically inactive NUDIX hydrolase domain-containing protein

1

2

High-throughput

0.437

High

196436

O44490
ELKS/RAB6-interacting/CAST family member 2

1

1

High-throughput

0.437

High

196438

LIN53
Probable histone-binding protein lin-53

1

13

High-throughput

0.437

High

196445

Q9TXM1
Uncharacterized protein

1

2

High-throughput

0.437

High

196442

Q22387
Centrosomal protein of 162 kDa

1

0

High-throughput

0.292

High

196443

DVE1
Homeobox protein dve-1

1

0

Small-scale

0.251

Low

196439

GLD1
Female germline-specific tumor suppressor gld-1

1

0

Small-scale

0.249

Low

145478

SWIC2
SWI/SNF chromatin-remodeling accessory subunit 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025