Protein: EXOS9
Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75)

Gene: EXOS9, EXOSC9
Organism: Homo sapiens
Interactions: 131
UniProt ID: Q06265

Gene Ontology (top 5):
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000228 - nuclear chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

986725

EXOS4
Exosome complex component RRP41

8

19

Small-scale

0.975

High

986677

EXOS7
Exosome complex component RRP42

7

18

Small-scale

0.963

High

986673

EXOS2
Exosome complex component RRP4

7

20

Small-scale

0.956

High

986709

EXOS8
Exosome complex component RRP43

5

18

High-throughput

0.927

High

986740

EXOS1
Exosome complex component CSL4

4

20

High-throughput

0.903

High

986727

EXOS5
Exosome complex component RRP46

3

19

High-throughput

0.871

High

986702

DI3L1
DIS3-like exonuclease 1

3

20

Small-scale

0.867

High

986681

EXOS6
Exosome complex component MTR3

2

17

High-throughput

0.789

High

986728

EXOS3
Exosome complex component RRP40

6

12

Small-scale

0.738

High

966390

EXOSX
Exosome complex component 10

5

12

Small-scale

0.706

High

986739

RRP44
Exosome complex exonuclease RRP44

1

20

Small-scale

0.691

High

986713

MPH6
M-phase phosphoprotein 6

4

5

Small-scale

0.689

High

986674

C1D
Nuclear nucleic acid-binding protein C1D

3

3

High-throughput

0.675

High

986742

HBS1L
HBS1-like protein

3

4

Small-scale

0.660

High

133455

NOP56
Nucleolar protein 56

2

7

High-throughput

0.611

High

986743

RBM7
RNA-binding protein 7

2

5

High-throughput

0.611

High

255709

OBSL1
Obscurin-like protein 1

2

2

High-throughput

0.584

High

986729

ANLN
Anillin

2

3

High-throughput

0.584

High

930162

UBC9
SUMO-conjugating enzyme UBC9

2

0

High-throughput

0.582

High

902543

SUMO2
Small ubiquitin-related modifier 2

2

0

High-throughput

0.577

High

369466

ESR1
Estrogen receptor

2

8

High-throughput

0.571

High

934121

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.545

High

801098

KI67
Proliferation marker protein Ki-67

1

3

High-throughput

0.536

High

805971

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.536

High

828746

SRP09
Signal recognition particle 9 kDa protein

1

1

High-throughput

0.536

High

907862

RS16
Small ribosomal subunit protein uS9

1

2

High-throughput

0.536

High

986676

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

8

High-throughput

0.536

High

986703

PHF10
PHD finger protein 10

1

4

High-throughput

0.536

High

986704

PSPC1
Paraspeckle component 1

1

5

High-throughput

0.536

High

986718

ZN106
Zinc finger protein 106

1

1

High-throughput

0.536

High

986738

DRG1
Developmentally-regulated GTP-binding protein 1

1

3

High-throughput

0.536

High

507406

ERG
Transcriptional regulator ERG

1

0

High-throughput

0.518

High

341202

HPT
Haptoglobin

1

0

High-throughput

0.513

High

644016

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.513

High

666891

TKT
Transketolase

1

0

High-throughput

0.513

High

986671

CUL3
Cullin-3

1

0

High-throughput

0.513

High

986675

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

986682

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

0

High-throughput

0.513

High

986683

DAB2P
Disabled homolog 2-interacting protein

1

0

High-throughput

0.513

High

986686

F111B
Serine protease FAM111B

1

0

High-throughput

0.513

High

986693

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

986708

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

986735

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.513

High

986689

SETX
Probable helicase senataxin

1

1

Small-scale

0.508

High

986719

CHM4B
Charged multivesicular body protein 4b

1

1

High-throughput

0.508

High

986694

ZDH17
Palmitoyltransferase ZDHHC17

1

3

High-throughput

0.494

High

986698

PARP8
Protein mono-ADP-ribosyltransferase PARP8

1

1

High-throughput

0.489

High

122689

MEN1
Menin

1

3

High-throughput

0.479

High

148710

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

227249

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

237204

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

3

High-throughput

0.479

High

294741

RECQ4
ATP-dependent DNA helicase Q4

1

4

High-throughput

0.479

High

296653

SLIT2
Slit homolog 2 protein

1

2

High-throughput

0.479

High

298450

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

312582

ARI2
E3 ubiquitin-protein ligase ARIH2

1

3

High-throughput

0.479

High

346601

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

374099

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

386588

P53
Cellular tumor antigen p53

1

2

High-throughput

0.479

High

438099

HS90B
Heat shock protein HSP 90-beta

1

1

High-throughput

0.479

High

442091

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

8

High-throughput

0.479

High

552560

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

582244

NUCL
Nucleolin

1

3

High-throughput

0.479

High

651026

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

668623

PML
Protein PML

1

2

High-throughput

0.479

High

720294

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

786932

MTREX
Exosome RNA helicase MTR4

1

12

High-throughput

0.479

High

813400

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.479

High

817959

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

851118

LUM
Lumican

1

2

High-throughput

0.479

High

856995

THOP1
Thimet oligopeptidase

1

3

High-throughput

0.479

High

877706

FOXA1
Hepatocyte nuclear factor 3-alpha

1

2

High-throughput

0.479

High

908423

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

918310

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

931107

YBOX1
Y-box-binding protein 1

1

5

Small-scale

0.479

High

934688

H31
Histone H3.1

1

1

High-throughput

0.479

High

986668

NFX1
Transcriptional repressor NF-X1

1

3

High-throughput

0.479

High

986669

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.479

High

986678

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

986679

EZH2
Histone-lysine N-methyltransferase EZH2

1

3

High-throughput

0.479

High

986680

E2F4
Transcription factor E2F4

1

1

High-throughput

0.479

High

986684

IFIX
Pyrin and HIN domain-containing protein 1

1

5

High-throughput

0.479

High

986685

ZCHC8
Zinc finger CCHC domain-containing protein 8

1

3

High-throughput

0.479

High

986687

GGYF2
GRB10-interacting GYF protein 2

1

3

High-throughput

0.479

High

986688

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

986690

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

986691

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

1

Small-scale

0.479

High

986692

ZCH18
Zinc finger CCCH domain-containing protein 18

1

5

High-throughput

0.479

High

986696

AHI1
Jouberin

1

6

Small-scale

0.479

High

986697

LRC47
Leucine-rich repeat-containing protein 47

1

2

High-throughput

0.479

High

986699

FBXW8
F-box/WD repeat-containing protein 8

1

2

High-throughput

0.479

High

986700

SIR6
NAD-dependent protein deacylase sirtuin-6

1

2

High-throughput

0.479

High

986701

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

986705

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

986706

HDAC2
Histone deacetylase 2

1

1

High-throughput

0.479

High

986707

KAT6A
Histone acetyltransferase KAT6A

1

4

High-throughput

0.479

High

986710

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

986711

RSRC1
Serine/Arginine-related protein 53

1

2

High-throughput

0.479

High

986714

ANM1
Protein arginine N-methyltransferase 1

1

3

High-throughput

0.479

High

986716

AICDA
Single-stranded DNA cytosine deaminase

1

3

Small-scale

0.479

High

986722

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

1

High-throughput

0.479

High

986723

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

3

High-throughput

0.479

High

986726

BRD7
Bromodomain-containing protein 7

1

2

High-throughput

0.479

High

986730

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

986733

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

4

High-throughput

0.479

High

986734

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

986737

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.479

High

308633

KI20A
Kinesin-like protein KIF20A

1

0

High-throughput

0.458

High

433718

LYN
Tyrosine-protein kinase Lyn

1

0

High-throughput

0.458

High

523689

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

652827

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

666383

3MG
DNA-3-methyladenine glycosylase

1

0

Small-scale

0.458

High

922134

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

986670

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

986695

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

986715

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

0

High-throughput

0.458

High

986720

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

986731

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

986741

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

986724

CHM1A
Charged multivesicular body protein 1a

1

1

High-throughput

0.457

High

986732

CHMP5
Charged multivesicular body protein 5

1

1

High-throughput

0.457

High

306126

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

2

High-throughput

0.445

High

401883

JUN
Transcription factor Jun

1

3

High-throughput

0.445

High

986717

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

2

High-throughput

0.445

High

986721

LN28A
Protein lin-28 homolog A

1

5

High-throughput

0.445

High

986672

DX39B
Spliceosome RNA helicase DDX39B

1

0

Small-scale

0.438

High

384700

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

981863

RON
Macrophage-stimulating protein receptor

1

3

High-throughput

0.437

High

986736

HECD1
E3 ubiquitin-protein ligase HECTD1

1

8

High-throughput

0.437

High

708873

MCM7
DNA replication licensing factor MCM7

1

0

Small-scale

0.426

High

110628

H3BNT4
M-phase phosphoprotein 6

1

5

High-throughput

0.407

High

986712

S35E1
Solute carrier family 35 member E1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024