Protein: EXOS1
Exosome complex component CSL4 (Exosome component 1)

Gene: EXOS1, EXOSC1
Organism: Homo sapiens
Interactions: 111
UniProt ID: Q9Y3B2

Gene Ontology (top 5):
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1343598

EXOS5
Exosome complex component RRP46

15

20

Small-scale

0.989

High

1285000

EXOS8
Exosome complex component RRP43

9

20

High-throughput

0.974

High

1342632

EXOS4
Exosome complex component RRP41

8

20

Small-scale

0.973

High

1063786

EXOS7
Exosome complex component RRP42

8

20

Small-scale

0.972

High

1130069

EXOS6
Exosome complex component MTR3

6

20

Small-scale

0.948

High

986740

EXOS9
Exosome complex component RRP45

4

20

High-throughput

0.903

High

1343616

EXOS3
Exosome complex component RRP40

9

7

Small-scale

0.754

High

966509

EXOSX
Exosome complex component 10

7

8

Small-scale

0.745

High

1046362

EXOS2
Exosome complex component RRP4

6

3

Small-scale

0.730

High

1257157

DI3L1
DIS3-like exonuclease 1

5

10

Small-scale

0.723

High

1304457

MPH6
M-phase phosphoprotein 6

5

3

Small-scale

0.716

High

1377594

HBS1L
HBS1-like protein

4

1

Small-scale

0.696

High

1174584

KCTD1
BTB/POZ domain-containing protein KCTD1

3

1

High-throughput

0.675

High

1047044

C1D
Nuclear nucleic acid-binding protein C1D

3

1

High-throughput

0.675

High

981794

REL
Proto-oncogene c-Rel

4

0

High-throughput

0.668

High

1157918

ZCHC8
Zinc finger CCHC domain-containing protein 8

3

1

High-throughput

0.667

High

1377595

RBM7
RNA-binding protein 7

3

1

High-throughput

0.667

High

1377242

MAST1
Microtubule-associated serine/threonine-protein kinase 1

2

4

High-throughput

0.633

High

908231

RS16
Small ribosomal subunit protein uS9

2

2

High-throughput

0.628

High

1330041

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

2

1

High-throughput

0.628

High

787038

MTREX
Exosome RNA helicase MTR4

2

8

High-throughput

0.611

High

735120

ZNF76
Zinc finger protein 76

2

1

High-throughput

0.606

High

856048

ZN143
Zinc finger protein 143

2

1

High-throughput

0.606

High

1191949

PTAR1
Protein prenyltransferase alpha subunit repeat-containing protein 1

2

0

High-throughput

0.602

High

1300065

BTBD9
BTB/POZ domain-containing protein 9

2

0

High-throughput

0.602

High

551326

ITF2
Transcription factor 4

2

0

High-throughput

0.601

High

1252565

LNX1
E3 ubiquitin-protein ligase LNX

2

0

High-throughput

0.580

High

1287695

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.580

High

1288768

ASB9
Ankyrin repeat and SOCS box protein 9

2

0

High-throughput

0.580

High

1350167

PAK5
Serine/threonine-protein kinase PAK 5

1

1

High-throughput

0.573

High

370775

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

1031728

GRB10
Growth factor receptor-bound protein 10

2

1

High-throughput

0.571

High

1274284

RBPMS
RNA-binding protein with multiple splicing

2

0

High-throughput

0.559

High

1297730

DMRTB
Doublesex- and mab-3-related transcription factor B1

2

0

High-throughput

0.559

High

230452

ZC3H1
Zinc finger C3H1 domain-containing protein

1

3

High-throughput

0.536

High

261617

NCOR1
Nuclear receptor corepressor 1

1

1

High-throughput

0.536

High

796675

KSYK
Tyrosine-protein kinase SYK

1

2

High-throughput

0.536

High

805855

RL27A
Large ribosomal subunit protein uL15

1

2

High-throughput

0.536

High

828950

SRP09
Signal recognition particle 9 kDa protein

1

1

High-throughput

0.536

High

893206

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.536

High

907788

RS15A
Small ribosomal subunit protein uS8

1

1

High-throughput

0.536

High

915128

RS4X
Small ribosomal subunit protein eS4, X isoform

1

1

High-throughput

0.536

High

983698

FAK1
Focal adhesion kinase 1

1

1

High-throughput

0.536

High

1016350

TBL3
Transducin beta-like protein 3

1

6

High-throughput

0.536

High

1069674

STK38
Serine/threonine-protein kinase 38

1

1

High-throughput

0.536

High

1246508

WDR36
WD repeat-containing protein 36

1

9

High-throughput

0.536

High

1298979

NSUN5
28S rRNA

1

1

High-throughput

0.536

High

1326856

AICDA
Single-stranded DNA cytosine deaminase

1

1

Small-scale

0.536

High

1355782

BAZ1B
Tyrosine-protein kinase BAZ1B

1

1

High-throughput

0.536

High

1357642

SRPK3
SRSF protein kinase 3

1

1

High-throughput

0.536

High

1377305

RRP44
Exosome complex exonuclease RRP44

1

10

Small-scale

0.536

High

1083058

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.518

High

1251342

EXOC6
Exocyst complex component 6

1

0

High-throughput

0.518

High

1309261

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.518

High

1327395

RNF32
RING finger protein 32

1

0

High-throughput

0.518

High

456022

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.513

High

588971

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.513

High

702191

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.513

High

722172

RFC2
Replication factor C subunit 2

1

0

High-throughput

0.513

High

920590

RS25
Small ribosomal subunit protein eS25

1

0

High-throughput

0.513

High

1063068

MO4L2
Mortality factor 4-like protein 2

1

0

High-throughput

0.513

High

1285848

SGK3
Serine/threonine-protein kinase Sgk3

1

0

High-throughput

0.513

High

1334905

RENT2
Regulator of nonsense transcripts 2

1

1

High-throughput

0.508

High

890904

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

High-throughput

0.501

High

1015968

NU160
Nuclear pore complex protein Nup160

1

0

High-throughput

0.486

High

1127736

PRC2B
Protein PRRC2B

1

2

High-throughput

0.481

High

396096

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

237352

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

2

High-throughput

0.479

High

323347

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

442616

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.479

High

578205

RL17
Large ribosomal subunit protein uL22

1

3

High-throughput

0.479

High

801981

RECQ1
ATP-dependent DNA helicase Q1

1

4

High-throughput

0.479

High

857021

THOP1
Thimet oligopeptidase

1

1

High-throughput

0.479

High

877968

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.479

High

918181

H4
Histone H4

1

2

High-throughput

0.479

High

1076148

OASL
2'-5'-oligoadenylate synthase-like protein

1

3

High-throughput

0.479

High

1146989

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1168016

GGYF2
GRB10-interacting GYF protein 2

1

2

High-throughput

0.479

High

1201789

ZCH18
Zinc finger CCCH domain-containing protein 18

1

2

High-throughput

0.479

High

1256498

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1269997

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1270997

KAT6A
Histone acetyltransferase KAT6A

1

3

High-throughput

0.479

High

1294162

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

1313312

MET22
Methyltransferase-like protein 22

1

1

High-throughput

0.479

High

1331695

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

1350135

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

2

High-throughput

0.479

High

1354955

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1357216

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

667738

NOS3
Nitric oxide synthase 3

1

0

High-throughput

0.460

High

912206

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

0

High-throughput

0.460

High

1044743

FHL3
Four and a half LIM domains protein 3

1

0

High-throughput

0.460

High

1075779

SF01
Splicing factor 1

1

0

High-throughput

0.460

High

1224448

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.460

High

1235836

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

0

High-throughput

0.460

High

1344264

SHLB2
Endophilin-B2

1

0

High-throughput

0.460

High

123113

MEN1
Menin

1

0

High-throughput

0.458

High

324691

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

909371

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1030051

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1044299

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.458

High

1056169

NBR1
Next to BRCA1 gene 1 protein

1

0

Small-scale

0.458

High

306363

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

3

High-throughput

0.445

High

348312

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.445

High

1310832

WDR83
WD repeat domain-containing protein 83

1

1

High-throughput

0.439

High

1040962

MTMR3
Myotubularin-related protein 3

1

0

Small-scale

0.438

High

110633

H3BNT4
M-phase phosphoprotein 6

1

3

High-throughput

0.407

High

111423

J3QQT2
Large ribosomal subunit protein uL22

1

3

High-throughput

0.407

High

344602

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.282

High

1223146

TEX11
Testis-expressed protein 11

1

0

High-throughput

0.251

Low

1053701

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

1167010

ATL4
ADAMTS-like protein 4

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024