Protein: ASF1A
Histone chaperone ASF1A (Anti-silencing function protein 1 homolog A) (hAsf1) (hAsf1a) (CCG1-interacting factor A) (CIA) (hCIA)

Gene: ASF1A
Organism: Homo sapiens
Interactions: 201
UniProt ID: Q9Y294

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0001649 - osteoblast differentiation
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

935389

H31
Histone H3.1

19

18

Small-scale

0.987

High

918163

H4
Histone H4

13

5

Small-scale

0.985

High

832791

MCM2
DNA replication licensing factor MCM2

9

11

Small-scale

0.974

High

952711

H33
Histone H3.3

9

18

Small-scale

0.972

High

1346793

ASF1B
Histone chaperone ASF1B

4

1

Small-scale

0.895

High

1086358

H31T
Histone H3.1t

2

18

Small-scale

0.806

High

867906

HIRA
Protein HIRA

14

17

Small-scale

0.763

High

1199551

TLK2
Serine/threonine-protein kinase tousled-like 2

8

6

Small-scale

0.755

High

825886

NASP
Nuclear autoantigenic sperm protein

9

2

Small-scale

0.754

High

1342765

UBN1
Ubinuclein-1

8

4

Small-scale

0.750

High

1356455

TLK1
Serine/threonine-protein kinase tousled-like 1

7

7

Small-scale

0.750

High

1219774

CDAN1
Codanin-1

6

3

Small-scale

0.742

High

1083435

RBBP7
Histone-binding protein RBBP7

6

5

Small-scale

0.738

High

997962

RBBP4
Histone-binding protein RBBP4

6

5

Small-scale

0.736

High

1377135

CABIN
Calcineurin-binding protein cabin-1

6

3

Small-scale

0.736

High

1293199

TONSL
Tonsoku-like protein

6

1

Small-scale

0.733

High

1137597

RIF1
Telomere-associated protein RIF1

5

4

High-throughput

0.722

High

1172651

UBN2
Ubinuclein-2

5

6

High-throughput

0.722

High

600260

TAF1
Transcription initiation factor TFIID subunit 1

1

7

Small-scale

0.710

High

1024612

CAF1B
Chromatin assembly factor 1 subunit B

4

14

Small-scale

0.709

High

158871

HAT1
Histone acetyltransferase type B catalytic subunit

4

2

High-throughput

0.704

High

1377131

CDIN1
CDAN1-interacting nuclease 1

4

1

High-throughput

0.704

High

1256995

IPO4
Importin-4

4

3

Small-scale

0.699

High

708548

MCM4
DNA replication licensing factor MCM4

3

10

Small-scale

0.667

High

709117

MCM7
DNA replication licensing factor MCM7

3

10

Small-scale

0.667

High

1055662

MCM6
DNA replication licensing factor MCM6

3

11

Small-scale

0.667

High

1123141

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

3

1

High-throughput

0.667

High

1024537

CAF1A
Chromatin assembly factor 1 subunit A

3

5

Small-scale

0.660

High

1174696

H32
Histone H3.2

1

18

Small-scale

0.646

High

370748

ESR1
Estrogen receptor

3

0

Small-scale

0.630

High

1119522

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

2

1

High-throughput

0.628

High

170516

TIF1A
Transcription intermediary factor 1-alpha

1

1

High-throughput

0.618

High

631636

BRD2
Bromodomain-containing protein 2

1

5

High-throughput

0.618

High

847119

SMCA4
Transcription activator BRG1

1

10

Small-scale

0.618

High

1357685

TRI33
E3 ubiquitin-protein ligase TRIM33

1

1

High-throughput

0.618

High

1246535

PPTC7
Protein phosphatase PTC7 homolog

2

1

High-throughput

0.574

High

345153

CYTA
Cystatin-A

1

1

High-throughput

0.536

High

422596

CENPB
Major centromere autoantigen B

1

2

High-throughput

0.536

High

906207

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

High-throughput

0.536

High

906641

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

1

High-throughput

0.536

High

964970

FABP5
Fatty acid-binding protein 5

1

1

High-throughput

0.536

High

1313143

HTAI2
Oxidoreductase HTATIP2

1

0

Small-scale

0.480

High

146299

ARI1A
AT-rich interactive domain-containing protein 1A

1

3

High-throughput

0.479

High

152703

KMT2D
Histone-lysine N-methyltransferase 2D

1

6

High-throughput

0.479

High

167176

ZN536
Zinc finger protein 536

1

1

High-throughput

0.479

High

175943

P73
Tumor protein p73

1

2

High-throughput

0.479

High

241387

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

1

High-throughput

0.479

High

256431

PHF2
Lysine-specific demethylase PHF2

1

1

High-throughput

0.479

High

261615

NCOR1
Nuclear receptor corepressor 1

1

4

High-throughput

0.479

High

295422

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

296182

MTA2
Metastasis-associated protein MTA2

1

1

High-throughput

0.479

High

299087

PHF14
PHD finger protein 14

1

1

High-throughput

0.479

High

321855

WIZ
Protein Wiz

1

1

High-throughput

0.479

High

387769

P53
Cellular tumor antigen p53

1

2

High-throughput

0.479

High

534156

T2FB
General transcription factor IIF subunit 2

1

1

High-throughput

0.479

High

727943

SOX6
Transcription factor SOX-6

1

1

High-throughput

0.479

High

848321

HCFC1
Host cell factor 1

1

1

High-throughput

0.479

High

867671

BLM
RecQ-like DNA helicase BLM

1

1

High-throughput

0.479

High

876629

AF17
Protein AF-17

1

1

High-throughput

0.479

High

970080

KIF23
Kinesin-like protein KIF23

1

3

High-throughput

0.479

High

975351

KMT2A
Histone-lysine N-methyltransferase 2A

1

5

High-throughput

0.479

High

975534

CENPC
Centromere protein C

1

1

High-throughput

0.479

High

1017264

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

1

Small-scale

0.479

High

1031975

MTA1
Metastasis-associated protein MTA1

1

1

High-throughput

0.479

High

1057029

MDC1
Mediator of DNA damage checkpoint protein 1

1

4

Small-scale

0.479

High

1057805

NCOA6
Nuclear receptor coactivator 6

1

7

High-throughput

0.479

High

1059577

KIF22
Kinesin-like protein KIF22

1

2

High-throughput

0.479

High

1060158

ARI5B
AT-rich interactive domain-containing protein 5B

1

4

High-throughput

0.479

High

1061294

NUMA1
Nuclear mitotic apparatus protein 1

1

1

High-throughput

0.479

High

1064272

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

1125910

BCORL
BCL-6 corepressor-like protein 1

1

4

High-throughput

0.479

High

1132373

ZN362
Zinc finger protein 362

1

1

High-throughput

0.479

High

1132760

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

3

High-throughput

0.479

High

1139099

TASO2
Protein TASOR 2

1

2

High-throughput

0.479

High

1147496

ARID2
AT-rich interactive domain-containing protein 2

1

4

High-throughput

0.479

High

1147789

SPT2
Protein SPT2 homolog

1

1

High-throughput

0.479

High

1159819

NFRKB
Nuclear factor related to kappa-B-binding protein

1

6

High-throughput

0.479

High

1164902

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

1

High-throughput

0.479

High

1167345

BCOR
BCL-6 corepressor

1

3

High-throughput

0.479

High

1170047

MMS22
Protein MMS22-like

1

1

High-throughput

0.479

High

1170100

SRCAP
Helicase SRCAP

1

10

High-throughput

0.479

High

1190888

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

8

High-throughput

0.479

High

1191036

RAI1
Retinoic acid-induced protein 1

1

5

High-throughput

0.479

High

1205433

KI18B
Kinesin-like protein KIF18B

1

1

High-throughput

0.479

High

1205838

P66A
Transcriptional repressor p66-alpha

1

1

High-throughput

0.479

High

1230905

ZN687
Zinc finger protein 687

1

1

High-throughput

0.479

High

1235317

MS3L1
MSL complex subunit 3

1

1

High-throughput

0.479

High

1244319

ARI1B
AT-rich interactive domain-containing protein 1B

1

5

High-throughput

0.479

High

1246389

THOC2
THO complex subunit 2

1

4

High-throughput

0.479

High

1254446

CHD6
Chromodomain-helicase-DNA-binding protein 6

1

7

High-throughput

0.479

High

1257283

ZN384
Zinc finger protein 384

1

1

High-throughput

0.479

High

1263998

P66B
Transcriptional repressor p66-beta

1

1

High-throughput

0.479

High

1267978

ZN592
Zinc finger protein 592

1

1

High-throughput

0.479

High

1268312

ZN516
Zinc finger protein 516

1

1

High-throughput

0.479

High

1296270

Z512B
Zinc finger protein 512B

1

3

High-throughput

0.479

High

1296827

NSD1
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

3

High-throughput

0.479

High

1296859

EP400
E1A-binding protein p400

1

11

High-throughput

0.479

High

1299879

LENG8
Leukocyte receptor cluster member 8

1

1

High-throughput

0.479

High

1300225

KI20B
Kinesin-like protein KIF20B

1

2

High-throughput

0.479

High

1300370

ATAD5
ATPase family AAA domain-containing protein 5

1

4

High-throughput

0.479

High

1302247

STRBP
Spermatid perinuclear RNA-binding protein

1

4

High-throughput

0.479

High

1302938

MINT
Msx2-interacting protein

1

1

High-throughput

0.479

High

1317727

NSD3
Histone-lysine N-methyltransferase NSD3

1

4

High-throughput

0.479

High

1327641

SP130
Histone deacetylase complex subunit SAP130

1

4

High-throughput

0.479

High

1330256

NELFA
Negative elongation factor A

1

3

High-throughput

0.479

High

1331904

ZN644
Zinc finger protein 644

1

1

High-throughput

0.479

High

1333262

KAT8
Histone acetyltransferase KAT8

1

2

Small-scale

0.479

High

1335006

CLSPN
Claspin

1

1

High-throughput

0.479

High

1336311

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

6

High-throughput

0.479

High

1342354

HM20A
High mobility group protein 20A

1

2

High-throughput

0.479

High

1343578

INCE
Inner centromere protein

1

1

High-throughput

0.479

High

1349291

BICRA
BRD4-interacting chromatin-remodeling complex-associated protein

1

8

High-throughput

0.479

High

1350245

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

7

High-throughput

0.479

High

1355190

TCF20
Transcription factor 20

1

5

High-throughput

0.479

High

1356948

YETS2
YEATS domain-containing protein 2

1

4

High-throughput

0.479

High

1357079

TPX2
Targeting protein for Xklp2

1

1

High-throughput

0.479

High

1357295

KMT2B
Histone-lysine N-methyltransferase 2B

1

3

High-throughput

0.479

High

1377134

NCOR2
Nuclear receptor corepressor 2

1

7

High-throughput

0.479

High

133735

NOP56
Nucleolar protein 56

1

0

High-throughput

0.458

High

236849

CCNT1
Cyclin-T1

1

0

High-throughput

0.458

High

312984

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.458

High

322035

ZMYM6
Zinc finger MYM-type protein 6

1

0

High-throughput

0.458

High

398973

HMGN2
Non-histone chromosomal protein HMG-17

1

0

High-throughput

0.458

High

486982

MYBB
Myb-related protein B

1

0

High-throughput

0.458

High

550447

ZEP1
Zinc finger protein 40

1

0

High-throughput

0.458

High

649174

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

0

High-throughput

0.458

High

719245

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

722656

T2FA
General transcription factor IIF subunit 1

1

0

High-throughput

0.458

High

727616

HNF1B
Hepatocyte nuclear factor 1-beta

1

0

High-throughput

0.458

High

749975

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

764720

CUX1
Homeobox protein cut-like 1

1

0

High-throughput

0.458

High

828644

CENPF
Centromere protein F

1

0

High-throughput

0.458

High

847932

BRCA2
Breast cancer type 2 susceptibility protein

1

0

High-throughput

0.458

High

876675

ELL
RNA polymerase II elongation factor ELL

1

0

High-throughput

0.458

High

964288

FOXK2
Forkhead box protein K2

1

0

High-throughput

0.458

High

1022808

PRDM2
PR domain zinc finger protein 2

1

0

High-throughput

0.458

High

1036220

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1041291

CUL1
Cullin-1

1

0

Small-scale

0.458

High

1051767

NPAT
Protein NPAT

1

0

High-throughput

0.458

High

1059205

CBX2
Chromobox protein homolog 2

1

0

High-throughput

0.458

High

1059603

MEF2D
Myocyte-specific enhancer factor 2D

1

0

High-throughput

0.458

High

1077266

ZN174
Zinc finger protein 174

1

0

High-throughput

0.458

High

1077621

ELF2
ETS-related transcription factor Elf-2

1

0

High-throughput

0.458

High

1121639

BOREA
Borealin

1

0

High-throughput

0.458

High

1133142

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.458

High

1133778

BEND3
BEN domain-containing protein 3

1

0

High-throughput

0.458

High

1148588

CDCA2
Cell division cycle-associated protein 2

1

0

High-throughput

0.458

High

1154434

LIN54
Protein lin-54 homolog

1

0

High-throughput

0.458

High

1161852

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

1189322

POGZ
Pogo transposable element with ZNF domain

1

0

High-throughput

0.458

High

1191154

I2BP2
Interferon regulatory factor 2-binding protein 2

1

0

High-throughput

0.458

High

1200827

CASZ1
Zinc finger protein castor homolog 1

1

0

High-throughput

0.458

High

1218738

MGAP
MAX gene-associated protein

1

0

High-throughput

0.458

High

1220011

SUGP1
SURP and G-patch domain-containing protein 1

1

0

High-throughput

0.458

High

1230573

CCAR2
Cell cycle and apoptosis regulator protein 2

1

0

High-throughput

0.458

High

1230944

CMTR1
Cap-specific mRNA

1

0

High-throughput

0.458

High

1241780

RN169
E3 ubiquitin-protein ligase RNF169

1

0

High-throughput

0.458

High

1256491

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1267655

PHF3
PHD finger protein 3

1

0

High-throughput

0.458

High

1270341

RREB1
Ras-responsive element-binding protein 1

1

0

High-throughput

0.458

High

1288180

ESS2
Splicing factor ESS-2 homolog

1

0

High-throughput

0.458

High

1295507

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.458

High

1298632

ZMAT2
Zinc finger matrin-type protein 2

1

0

High-throughput

0.458

High

1311644

SEN34
tRNA-splicing endonuclease subunit Sen34

1

0

High-throughput

0.458

High

1314988

FANCJ
Fanconi anemia group J protein

1

0

High-throughput

0.458

High

1327555

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

1332106

STEEP
STING ER exit protein

1

0

High-throughput

0.458

High

1343816

ANLN
Anillin

1

0

High-throughput

0.458

High

1347952

TEX10
Testis-expressed protein 10

1

0

High-throughput

0.458

High

1354906

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1355450

TRPS1
Zinc finger transcription factor Trps1

1

0

High-throughput

0.458

High

1356509

C8AP2
CASP8-associated protein 2

1

0

High-throughput

0.458

High

1377130

FBW1A
F-box/WD repeat-containing protein 1A

1

0

Small-scale

0.458

High

1377132

ZN281
Zinc finger protein 281

1

0

High-throughput

0.458

High

1377133

SALL2
Sal-like protein 2

1

0

High-throughput

0.458

High

321256

PTBP3
Polypyrimidine tract-binding protein 3

1

1

High-throughput

0.445

High

1334610

LN28A
Protein lin-28 homolog A

1

1

High-throughput

0.445

High

632448

TNR6
Tumor necrosis factor receptor superfamily member 6

1

1

High-throughput

0.437

High

1101073

QSER1
Glutamine and serine-rich protein 1

1

4

High-throughput

0.437

High

1146977

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.437

High

1044287

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.426

High

110647

H3BPZ6
Codanin 1

1

3

High-throughput

0.407

High

945392

PRR3
Proline-rich protein 3

3

0

High-throughput

0.352

High

1216600

ZDH17
Palmitoyltransferase ZDHHC17

1

0

High-throughput

0.282

High

164677

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

0

High-throughput

0.279

Low

608888

SPR1B
Cornifin-B

1

0

High-throughput

0.279

Low

813859

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.279

Low

863375

COPB
Coatomer subunit beta

1

0

High-throughput

0.279

Low

984684

CALD1
Caldesmon

1

0

High-throughput

0.279

Low

1052353

SRC8
Src substrate cortactin

1

0

High-throughput

0.279

Low

1204618

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.279

Low

1236014

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

0

High-throughput

0.279

Low

1336561

S10AE
Protein S100-A14

1

0

High-throughput

0.279

Low

1349433

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.279

Low

1057874

GSE1
Genetic suppressor element 1

1

0

High-throughput

0.249

Low

1078958

TBCE
Tubulin-specific chaperone E

1

0

High-throughput

0.249

Low

1155827

RADX
RPA-related protein RADX

1

0

High-throughput

0.249

Low

1172324

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1292687

DDX27
Probable ATP-dependent RNA helicase DDX27

1

0

High-throughput

0.249

Low

934614

PA1B2
Platelet-activating factor acetylhydrolase IB subunit alpha2

1

0

High-throughput

0.238

Low

1356287

VPS28
Vacuolar protein sorting-associated protein 28 homolog

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024