Protein: MEC3
Mechanosensory protein 3

Gene: MEC3, mec-3
Organism: Caenorhabditis elegans
Interactions: 85
UniProt ID: P09088

Gene Ontology (top 5):
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

478964

UNC86
Transcription factor unc-86

3

10

Small-scale

0.835

High

111459

PAX3H
Paired box protein 3 homolog

1

11

High-throughput

0.656

High

478965

HM14
LIM/homeobox protein ceh-14

1

17

High-throughput

0.656

High

478968

WBS14
Protein WBSCR14 homolog

1

15

High-throughput

0.656

High

478990

HM30
Homeobox protein ceh-30

1

20

High-throughput

0.656

High

479006

UNC62
Homeobox protein unc-62

1

7

High-throughput

0.656

High

479010

HMBX1
Homeobox-containing protein 1

1

14

High-throughput

0.656

High

479019

Q9XVN4
Homeobox domain-containing protein

1

16

High-throughput

0.656

High

112575

LIDB1
LIM domain-binding protein 1

1

20

Small-scale

0.621

High

111895

VAB3
Paired box protein 6 homolog

1

8

High-throughput

0.590

High

117753

UNC42
Homeobox protein unc-42

1

16

High-throughput

0.590

High

111005

G5ECN8
C2H2-type domain-containing protein

1

5

High-throughput

0.508

High

112009

G5EDU4
EOR-1

1

5

High-throughput

0.508

High

112059

OVOLH
Transcription factor ovo-like homolog lin-48

1

4

High-throughput

0.508

High

112586

G5EEL3
Nuclear Hormone Receptor family

1

13

High-throughput

0.508

High

145353

O01960
C2H2-type domain-containing protein

1

10

High-throughput

0.508

High

145834

O02273
C2H2-type domain-containing protein

1

15

High-throughput

0.508

High

145861

NHR62
Nuclear hormone receptor family member nhr-62

1

20

High-throughput

0.508

High

233427

O44719
C2H2-type domain-containing protein

1

1

High-throughput

0.508

High

233924

NH111
Nuclear hormone receptor family member nhr-111

1

19

High-throughput

0.508

High

264167

KLF2
Kruppel-like factor 2

1

9

High-throughput

0.508

High

478966

LIN36
Protein lin-36

1

6

High-throughput

0.508

High

478970

SWIC1
SWI/SNF chromatin-remodeling accessory subunit 1

1

12

High-throughput

0.508

High

478971

PHA4
Defective pharyngeal development protein 4

1

7

High-throughput

0.508

High

478972

SPE44
Transcription regulator spe-44

1

8

High-throughput

0.508

High

478973

Q18241
Helicase ARIP4

1

11

High-throughput

0.508

High

478974

NHR43
Nuclear hormone receptor family member nhr-43

1

17

High-throughput

0.508

High

478976

UN130
Forkhead box protein unc-130

1

7

High-throughput

0.508

High

478979

TRA4
Zinc finger protein tra-4

1

11

High-throughput

0.508

High

478982

NFIL3
Transcription factor atf-2

1

4

High-throughput

0.508

High

478983

Q21372
Nuclear Hormone Receptor family

1

12

High-throughput

0.508

High

478984

Q21777
C2H2-type domain-containing protein

1

4

High-throughput

0.508

High

478988

SPTF2
Specificity protein transcription factor 2

1

6

High-throughput

0.508

High

478989

KMT5A
Histone-lysine N-methyltransferase set-1

1

10

High-throughput

0.508

High

478991

EGL13
Transcription factor egl-13

1

14

High-throughput

0.508

High

478993

KDM5
Lysine-specific demethylase rbr-2

1

8

High-throughput

0.508

High

478998

BLMP1
B lymphocyte-induced maturation protein 1 homolog

1

6

High-throughput

0.508

High

478999

Q95QB3
Nuclear Hormone Receptor family

1

12

High-throughput

0.508

High

479002

Q9BKZ8
Nuclear receptor domain-containing protein

1

20

High-throughput

0.508

High

479008

ODD2
Protein odd-skipped-related 2

1

11

High-throughput

0.508

High

479011

TIP60
Histone acetyltransferase Tip60 homolog

1

1

High-throughput

0.508

High

479012

KLF1
Kruppel-like factor 1

1

13

High-throughput

0.508

High

479015

Q9U235
C2H2-type domain-containing protein

1

8

High-throughput

0.508

High

479020

NHR67
Nuclear hormone receptor family member nhr-67

1

16

High-throughput

0.508

High

478986

Q22173
AT hook Transcription Factor family

1

0

High-throughput

0.486

High

478992

Q23170
C3H1-type domain-containing protein

1

0

High-throughput

0.486

High

478994

LI15A
Protein lin-15A

1

0

High-throughput

0.486

High

479003

Q9GYG1
C2H2-type domain-containing protein

1

0

High-throughput

0.486

High

479013

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.486

High

479017

ZIP3
Transcription factor zip-3

1

0

High-throughput

0.486

High

479022

Q9XWJ8
Inhibitor of growth protein

1

0

High-throughput

0.486

High

72190

A8WHS5
Suppressor of activated egl-4 protein 1

1

9

High-throughput

0.481

High

115606

H2KZU3
NR LBD domain-containing protein

1

20

High-throughput

0.481

High

145686

O02174
C3H1-type domain-containing protein

1

5

High-throughput

0.481

High

478985

Q21970
Zmiz1 N-terminal tetratricopeptide repeat domain-containing protein

1

11

High-throughput

0.481

High

478997

Q86PI8
Nuclear receptor NHR-114

1

17

High-throughput

0.481

High

479000

Q9BHL3
C2H2-type domain-containing protein

1

4

High-throughput

0.481

High

110720

G5ECB9
C3H1-type domain-containing protein

1

1

High-throughput

0.464

High

233716

O45134
X chromosome NonDisjunction factor

1

1

High-throughput

0.464

High

478969

RAPSN
43 kDa receptor-associated protein of the synapse homolog

1

6

High-throughput

0.464

High

478975

Q18477
Histone deacetylase 11

1

5

High-throughput

0.464

High

478977

Q18782
RING-type E3 ubiquitin transferase

1

4

High-throughput

0.464

High

478978

Q19760
JmjC domain-containing protein

1

4

High-throughput

0.464

High

478981

Q21177
Uncharacterized protein

1

12

High-throughput

0.464

High

479018

MOE3
CCCH-type zinc finger protein moe-3

1

1

High-throughput

0.464

High

112619

NH114
Nuclear hormone receptor 114

1

16

High-throughput

0.457

High

115514

H2KZI6
C3H1-type domain-containing protein

1

5

High-throughput

0.457

High

115630

H2KZU4
NR LBD domain-containing protein

1

20

High-throughput

0.457

High

115706

ZTF16
Zinc finger protein ztf-16

1

20

High-throughput

0.457

High

478980

SAEG1
Suppressor of activated egl-4 protein 1

1

6

High-throughput

0.457

High

478995

EHN3
Zinc finger protein ehn-3

1

8

High-throughput

0.457

High

478996

SMA9
Transcription factor sma-9

1

10

High-throughput

0.457

High

479001

Q9BHL4
C2H2-type domain-containing protein

1

4

High-throughput

0.457

High

479007

LSY2
Zinc finger protein lsy-2

1

8

High-throughput

0.457

High

479014

TAF12
Transcription initiation factor TFIID subunit 12

1

2

High-throughput

0.457

High

479016

CREBH
CREB homolog crh-1

1

1

High-throughput

0.457

High

478967

ZFP1
Zinc finger protein zfp-1

1

0

High-throughput

0.438

High

233686

O45075
PHD-type domain-containing protein

1

8

High-throughput

0.417

High

103960

F5GU47
C2H2-type domain-containing protein

1

0

High-throughput

0.265

Low

145329

O01933
C2H2-type domain-containing protein

1

0

High-throughput

0.265

Low

478987

Q22676
C2H2-type domain-containing protein

1

0

High-throughput

0.265

Low

479004

MKRN
E3 ubiquitin-protein ligase makorin

1

0

High-throughput

0.265

Low

479005

Q9N410
BHLH domain-containing protein

1

0

High-throughput

0.265

Low

479009

TAF2
Transcription initiation factor TFIID subunit 2

1

0

High-throughput

0.265

Low

479021

Q9XW80
BZIP domain-containing protein

1

0

High-throughput

0.265

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025