Protein: NELFE
Negative elongation factor E (NELF-E) (RNA-binding protein RD)

Gene: NELFE
Organism: Homo sapiens
Interactions: 87
UniProt ID: P18615

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0003723 - RNA binding
GO:0003729 - mRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

577739

NCBP2
Nuclear cap-binding protein subunit 2

3

12

High-throughput

0.830

High

577752

NCBP1
Nuclear cap-binding protein subunit 1

2

1

High-throughput

0.776

High

577775

NELFB
Negative elongation factor B

11

1

Small-scale

0.760

High

577769

NELFD
Negative elongation factor C/D

8

1

Small-scale

0.756

High

577781

NELFA
Negative elongation factor A

7

1

Small-scale

0.753

High

577747

SRPK2
SRSF protein kinase 2

1

3

High-throughput

0.735

High

577778

SRPK1
SRSF protein kinase 1

1

2

High-throughput

0.735

High

577751

SRSF1
Serine/arginine-rich splicing factor 1

1

10

High-throughput

0.691

High

577735

SMBP2
DNA-binding protein SMUBP-2

3

3

High-throughput

0.667

High

577731

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.656

High

577740

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.656

High

268603

SF3B1
Splicing factor 3B subunit 1

1

1

High-throughput

0.618

High

373651

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.618

High

441871

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

14

High-throughput

0.618

High

577743

1433G
14-3-3 protein gamma

2

6

High-throughput

0.611

High

577786

RRP44
Exosome complex exonuclease RRP44

2

0

High-throughput

0.585

High

536724

TRI27
Zinc finger protein RFP

1

0

High-throughput

0.549

High

577760

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

0

High-throughput

0.549

High

123848

SPT5H
Transcription elongation factor SPT5

1

4

High-throughput

0.536

High

559540

H12
Histone H1.2

1

1

High-throughput

0.536

High

577744

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.536

High

577745

1433Z
14-3-3 protein zeta/delta

1

5

High-throughput

0.536

High

577750

1433F
14-3-3 protein eta

1

6

High-throughput

0.536

High

577758

CCD57
Coiled-coil domain-containing protein 57

1

1

High-throughput

0.523

High

577757

VAMP3
Vesicle-associated membrane protein 3

1

0

High-throughput

0.518

High

577762

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

3

High-throughput

0.515

High

416565

S10A6
Protein S100-A6

1

0

High-throughput

0.513

High

577722

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.513

High

577723

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.513

High

577724

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

0

High-throughput

0.513

High

577726

LORI
Loricrin

1

0

High-throughput

0.513

High

577742

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.513

High

577749

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.513

High

577764

INT5
Integrator complex subunit 5

1

0

High-throughput

0.513

High

261398

NCOR1
Nuclear receptor corepressor 1

1

1

Small-scale

0.508

High

577773

WDR48
WD repeat-containing protein 48

1

0

High-throughput

0.493

High

577728

1433T
14-3-3 protein theta

1

6

High-throughput

0.489

High

577732

1433B
14-3-3 protein beta/alpha

1

6

High-throughput

0.489

High

310034

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

1

0

Small-scale

0.480

High

125145

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

1

High-throughput

0.479

High

226475

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

243904

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.479

High

322165

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

345881

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.479

High

359646

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.479

High

384233

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

437877

HS90B
Heat shock protein HSP 90-beta

1

4

Small-scale

0.479

High

487117

ANDR
Androgen receptor

1

4

High-throughput

0.479

High

523508

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

551909

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

569153

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

577727

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

Small-scale

0.479

High

577729

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

577730

PML
Protein PML

1

2

High-throughput

0.479

High

577734

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

577736

YAP1
Transcriptional coactivator YAP1

1

2

High-throughput

0.479

High

577741

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

2

High-throughput

0.479

High

577748

VIGLN
Vigilin

1

7

High-throughput

0.479

High

577753

EP300
Histone acetyltransferase p300

1

2

High-throughput

0.479

High

577756

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

577759

BRDT
Bromodomain testis-specific protein

1

3

High-throughput

0.479

High

577766

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

577771

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.479

High

577777

RSRC1
Serine/Arginine-related protein 53

1

1

High-throughput

0.479

High

577782

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

577785

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

577774

CATIN
Splicing factor Cactin

1

0

Small-scale

0.460

High

577754

FOXC1
Forkhead box protein C1

1

0

High-throughput

0.458

High

577755

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

577767

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

577770

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

0

High-throughput

0.458

High

577779

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

577780

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

577783

WDR76
WD repeat-containing protein 76

1

0

High-throughput

0.458

High

577784

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

110874

H7C5Q0
Arginine and serine rich coiled-coil 1

1

1

High-throughput

0.445

High

577746

ACTC
Actin, alpha cardiac muscle 1

1

2

High-throughput

0.437

High

577763

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

577765

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

577737

CEBPA
CCAAT/enhancer-binding protein alpha

1

3

High-throughput

0.408

High

577725

HEMH
Ferrochelatase, mitochondrial

2

0

High-throughput

0.328

High

577733

TRY3
Trypsin-3

1

0

High-throughput

0.279

Low

577738

CP2J2
Cytochrome P450 2J2

1

0

High-throughput

0.279

Low

577761

KPLCE
Protein KPLCE

1

0

High-throughput

0.279

Low

577768

XYLT1
Xylosyltransferase 1

1

0

High-throughput

0.279

Low

577772

TTC29
Tetratricopeptide repeat protein 29

1

0

High-throughput

0.249

Low

577776

TM141
Transmembrane protein 141

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024