Protein: RBL2
Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2)

Gene: RBL2
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q08999

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0005654 - nucleoplasm
GO:0005667 - transcription regulator complex
GO:0005694 - chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

625392

CDK2
Cyclin-dependent kinase 2

12

9

Small-scale

0.760

High

997125

E2F4
Transcription factor E2F4

13

20

Small-scale

0.758

High

660124

RBL1
Retinoblastoma-like protein 1

2

2

Small-scale

0.754

High

997137

CTIP
DNA endonuclease RBBP8

6

3

Small-scale

0.734

High

590169

CCNA2
Cyclin-A2

6

7

Small-scale

0.732

High

673145

CCND3
G1/S-specific cyclin-D3

5

20

Small-scale

0.723

High

997127

LIN9
Protein lin-9 homolog

4

5

Small-scale

0.697

High

997135

LIN37
Protein lin-37 homolog

4

3

Small-scale

0.697

High

997129

LIN54
Protein lin-54 homolog

3

5

Small-scale

0.667

High

673066

CCND2
G1/S-specific cyclin-D2

3

18

High-throughput

0.667

High

997123

E2F5
Transcription factor E2F5

3

20

Small-scale

0.660

High

997110

HDAC1
Histone deacetylase 1

3

12

Small-scale

0.650

High

515411

CDK4
Cyclin-dependent kinase 4

2

19

Small-scale

0.643

High

997105

RBBP4
Histone-binding protein RBBP4

2

9

Small-scale

0.635

High

997116

TFDP2
Transcription factor Dp-2

2

11

Small-scale

0.635

High

963598

E2F1
Transcription factor E2F1

3

20

Small-scale

0.633

High

718793

PHB1
Prohibitin 1

2

2

Small-scale

0.631

High

930815

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

2

6

Small-scale

0.629

High

997126

LIN52
Protein lin-52 homolog

2

3

Small-scale

0.629

High

530792

RARG
Retinoic acid receptor gamma

2

3

High-throughput

0.628

High

997144

DYR1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B

2

14

High-throughput

0.628

High

758202

CDN1A
Cyclin-dependent kinase inhibitor 1

2

3

High-throughput

0.611

High

997131

TXD11
Thioredoxin domain-containing protein 11

3

1

High-throughput

0.609

High

749419

BRCA1
Breast cancer type 1 susceptibility protein

2

3

Small-scale

0.595

High

997108

SKP2
S-phase kinase-associated protein 2

2

2

Small-scale

0.595

High

624579

CCNE1
G1/S-specific cyclin-E1

2

12

Small-scale

0.584

High

970562

ID2
DNA-binding protein inhibitor ID-2

2

3

Small-scale

0.584

High

374116

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

Small-scale

0.573

High

997130

RINT1
RAD50-interacting protein 1

1

2

Small-scale

0.573

High

960159

CDK6
Cyclin-dependent kinase 6

1

20

Small-scale

0.569

High

997106

TP53B
TP53-binding protein 1

1

1

Small-scale

0.561

High

997124

EZH2
Histone-lysine N-methyltransferase EZH2

1

9

Small-scale

0.561

High

997134

TF3B
Transcription factor IIIB 90 kDa subunit

1

3

Small-scale

0.561

High

997136

NEB2
Neurabin-2

1

2

Small-scale

0.561

High

997115

TFDP1
Transcription factor Dp-1

1

11

Small-scale

0.554

High

538529

CCNB1
G2/mitotic-specific cyclin-B1

1

7

High-throughput

0.536

High

586705

CSK22
Casein kinase II subunit alpha'

1

14

High-throughput

0.536

High

668630

PML
Protein PML

1

3

Small-scale

0.536

High

902890

DCAF7
DDB1- and CUL4-associated factor 7

1

13

High-throughput

0.536

High

934126

CSK21
Casein kinase II subunit alpha

1

12

High-throughput

0.536

High

952800

FOXK1
Forkhead box protein K1

1

7

High-throughput

0.536

High

958440

CYC
Cytochrome c

1

1

High-throughput

0.536

High

997114

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

14

High-throughput

0.536

High

997120

IRF3
Interferon regulatory factor 3

1

2

High-throughput

0.536

High

997138

CITE1
Cbp/p300-interacting transactivator 1

1

2

High-throughput

0.536

High

997112

DGKZ
Diacylglycerol kinase zeta

1

5

Small-scale

0.534

High

571807

XBP1
X-box-binding protein 1

1

0

High-throughput

0.518

High

900031

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.518

High

111134

I6L8A6
DNA endonuclease RBBP8

1

3

High-throughput

0.515

High

708877

MCM7
DNA replication licensing factor MCM7

1

2

Small-scale

0.501

High

943777

CCNA1
Cyclin-A1

1

7

Small-scale

0.501

High

997107

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

2

Small-scale

0.501

High

997111

SNW1
SNW domain-containing protein 1

1

2

Small-scale

0.501

High

331639

CCNE2
G1/S-specific cyclin-E2

1

14

Small-scale

0.484

High

233832

HBP1
HMG box-containing protein 1

1

3

Small-scale

0.481

High

622439

CCND1
G1/S-specific cyclin-D1

1

20

Small-scale

0.481

High

846945

SMCA4
Transcription activator BRG1

1

5

Small-scale

0.481

High

858128

LBX1
Transcription factor LBX1

1

2

Small-scale

0.481

High

203671

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

3

Small-scale

0.479

High

276968

RBBP9
Serine hydrolase RBBP9

1

4

Small-scale

0.479

High

545965

MYOD1
Myoblast determination protein 1

1

5

Small-scale

0.479

High

600134

TAF1
Transcription initiation factor TFIID subunit 1

1

6

Small-scale

0.479

High

841679

CDK9
Cyclin-dependent kinase 9

1

17

High-throughput

0.479

High

997109

CTBP1
C-terminal-binding protein 1

1

2

Small-scale

0.479

High

997113

CUL1
Cullin-1

1

2

Small-scale

0.479

High

997119

BECN1
Beclin-1

1

2

Small-scale

0.479

High

997121

SUZ12
Polycomb protein SUZ12

1

2

Small-scale

0.479

High

997141

AATF
Protein AATF

1

2

Small-scale

0.479

High

997142

TRI33
E3 ubiquitin-protein ligase TRIM33

1

3

High-throughput

0.479

High

997143

PA2G4
Proliferation-associated protein 2G4

1

2

Small-scale

0.479

High

431314

LDHC
L-lactate dehydrogenase C chain

1

0

Small-scale

0.460

High

997118

DCTN1
Dynactin subunit 1

1

0

Small-scale

0.460

High

928887

SKP1
S-phase kinase-associated protein 1

1

0

Small-scale

0.458

High

997133

RAD50
DNA repair protein RAD50

1

0

Small-scale

0.458

High

386613

P53
Cellular tumor antigen p53

1

3

High-throughput

0.445

High

397027

PAI2
Plasminogen activator inhibitor 2

1

1

Small-scale

0.437

High

997122

CDK10
Cyclin-dependent kinase 10

1

11

High-throughput

0.437

High

997132

SNX19
Sorting nexin-19

1

2

Small-scale

0.437

High

597499

GSTM3
Glutathione S-transferase Mu 3

1

0

Small-scale

0.426

High

997139

ISCU
Iron-sulfur cluster assembly enzyme ISCU

1

0

Small-scale

0.426

High

508476

TOP1
DNA topoisomerase 1

1

1

Small-scale

0.408

High

997117

BTG3
Protein BTG3

1

0

High-throughput

0.282

High

997128

GRAM4
GRAM domain-containing protein 4

1

0

Small-scale

0.251

Low

997140

TMLH
Trimethyllysine dioxygenase, mitochondrial

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024