Protein: Q9GUP2
HECT-type E3 ubiquitin transferase (EC 2.3.2.26)

Gene: Q9GUP2, eel-1
Organism: Caenorhabditis elegans
Interactions: 30
UniProt ID: Q9GUP2

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0010468 - regulation of gene expression
GO:0016567 - protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1165107

PK1
Serine/threonine-protein kinase pak-1

1

18

Small-scale

0.621

High

110103

SMA5
Mitogen-activated protein kinase sma-5

1

2

Small-scale

0.618

High

111981

G5EDT9
E3 ubiquitin-protein ligase UBR5

1

16

Small-scale

0.618

High

509830

UBIQ1
Polyubiquitin-A [Cleaved into: Ubiquitin; Ubiquitin-related]

1

20

Small-scale

0.618

High

759043

PLK1
Serine/threonine-protein kinase plk-1

1

6

High-throughput

0.618

High

1427940

MBK2
Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2

1

15

High-throughput

0.618

High

114011

TAF1
Transcription initiation factor TFIID subunit 1

1

5

Small-scale

0.479

High

196767

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase

1

12

Small-scale

0.479

High

233324

O44503
Saccharopine dehydrogenase

1

1

Small-scale

0.479

High

760093

GLH1
ATP-dependent RNA helicase glh-1

1

12

High-throughput

0.479

High

1066882

EGL27
Egg-laying defective protein 27

1

10

Small-scale

0.479

High

1171042

DYL1
Dynein light chain 1, cytoplasmic

1

1

Small-scale

0.479

High

1374008

PLP1
Transcriptional activator plp-1

1

1

Small-scale

0.479

High

1427937

Q9N3F4
RNA helicase

1

11

Small-scale

0.479

High

1427938

Q9TXM1
Uncharacterized protein

1

1

High-throughput

0.479

High

1427939

LIN41
Protein lin-41

1

13

Small-scale

0.479

High

760190

SKN1
Protein skinhead-1

1

0

Small-scale

0.460

High

112990

KY
Lim and transglutaminase domain protein ltd-1

1

0

Small-scale

0.458

High

1301815

GLS1
Germline survival defective-1

1

0

Small-scale

0.458

High

113584

G5EFX3
Multiple epidermal growth factor-like domains protein 6

1

11

Small-scale

0.437

High

115570

H2KZN0
RRM domain-containing protein

1

17

Small-scale

0.437

High

145823

O02254
FERM domain-containing protein 8

1

13

Small-scale

0.437

High

1018451

GPDM
Probable glycerol-3-phosphate dehydrogenase, mitochondrial

1

3

Small-scale

0.437

High

1068061

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

1

Small-scale

0.437

High

1379792

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

12

Small-scale

0.437

High

233370

RF1M
Probable peptide chain release factor 1, mitochondrial

1

0

Small-scale

0.249

Low

1164891

Q17492
F-box domain-containing protein

1

0

Small-scale

0.249

Low

1166800

Q19591
Secreted protein

1

0

Small-scale

0.249

Low

1427941

Q9XU04
SPK domain-containing protein

1

0

Small-scale

0.249

Low

1427942

Q9XU45
Uncharacterized protein

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025