Protein: IRS1
Insulin receptor substrate 1 (dIRS) (Protein chico)

Gene: IRS1, chico
Organism: Drosophila melanogaster
Interactions: 31
UniProt ID: Q9XTN2

Gene Ontology (top 5):
GO:0005158 - insulin receptor binding
GO:0005159 - insulin-like growth factor receptor binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1178934

Q7K137
LD10453p

2

17

Small-scale

0.768

High

448264

INSR
Insulin-like receptor

8

14

Small-scale

0.746

High

664678

1433Z
14-3-3 protein zeta

4

20

Small-scale

0.686

High

955052

1433E
14-3-3 protein epsilon

4

5

Small-scale

0.686

High

113958

M9PAY7
Pi3K21B, isoform C

3

20

High-throughput

0.640

High

1376023

DOS
Protein daughter of sevenless

1

1

High-throughput

0.618

High

1368279

Q9VJ14
RING-type E3 ubiquitin transferase

2

3

High-throughput

0.611

High

954625

P91634
PI-3 kinase

2

7

High-throughput

0.584

High

186292

O18683
LD42724p

2

20

High-throughput

0.538

High

820841

PELO
Protein pelota

1

0

High-throughput

0.486

High

247496

FLOT1
Flotillin-1

1

3

High-throughput

0.479

High

247541

FLOT2
Flotillin-2

1

3

High-throughput

0.479

High

669840

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.479

High

734252

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

1

2

High-throughput

0.479

High

737616

2ABA
Protein phosphatase PP2A 55 kDa regulatory subunit

1

1

High-throughput

0.479

High

1119176

RBP9X
Ran-binding proteins 9/10 homolog

1

2

High-throughput

0.479

High

1376856

Q9Y162
BcDNA.GH02678

1

1

High-throughput

0.437

High

993227

GRAP
Growth factor receptor-bound protein 2

1

12

High-throughput

0.381

High

220927

PGAM5
Serine/threonine-protein phosphatase Pgam5, mitochondrial

1

0

High-throughput

0.279

Low

116123

M9PHL4
IST1 homolog

1

0

High-throughput

0.249

Low

448169

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.249

Low

524765

RS26
Small ribosomal subunit protein eS26

1

0

High-throughput

0.249

Low

803341

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.249

Low

816424

RS15A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

878937

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.249

Low

1280750

Q961X4
Combover, isoform B

1

0

High-throughput

0.249

Low

1368293

Q9VJ19
Large ribosomal subunit protein eL30

1

0

High-throughput

0.249

Low

1373426

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.249

Low

1374792

CHMP5
Charged multivesicular body protein 5

1

0

High-throughput

0.249

Low

1375017

Q9VW70
FI21813p1

1

0

High-throughput

0.249

Low

1376572

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024