Protein: TNR5
Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CDw40) (CD antigen CD40)

Gene: TNR5, CD40
Organism: Homo sapiens
Interactions: 159
UniProt ID: P25942

Gene Ontology (top 5):
GO:0001934 - positive regulation of protein phosphorylation
GO:0002768 - immune response-regulating cell surface receptor signaling pathway
GO:0003823 - antigen binding
GO:0005886 - plasma membrane
GO:0006874 - intracellular calcium ion homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

639551

CD40L
CD40 ligand

3

20

Small-scale

0.827

High

639664

TN13B
Tumor necrosis factor ligand superfamily member 13B

2

4

Small-scale

0.776

High

639576

TRAF2
TNF receptor-associated factor 2

31

20

Small-scale

0.769

High

639578

TRAF3
TNF receptor-associated factor 3

28

20

Small-scale

0.768

High

639668

TRAF6
TNF receptor-associated factor 6

14

20

Small-scale

0.761

High

129532

TRAF5
TNF receptor-associated factor 5

11

20

Small-scale

0.754

High

639577

TRAF1
TNF receptor-associated factor 1

4

20

Small-scale

0.683

High

639653

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

3

2

High-throughput

0.665

High

639581

BIRC2
Baculoviral IAP repeat-containing protein 2

3

12

Small-scale

0.640

High

212242

CIKS
E3 ubiquitin ligase TRAF3IP2

3

0

Small-scale

0.622

High

639548

TNR5
Tumor necrosis factor receptor superfamily member 5

1

15

Small-scale

0.618

High

639552

MIP
Lens fiber major intrinsic protein

2

1

High-throughput

0.606

High

639553

CTR1
High affinity cationic amino acid transporter 1

2

2

High-throughput

0.606

High

639569

MYPR
Myelin proteolipid protein

2

2

High-throughput

0.606

High

639597

MFSD5
Molybdate-anion transporter

2

1

High-throughput

0.606

High

639612

CYAC3
Lysosomal membrane ascorbate-dependent ferrireductase CYB561A3

2

1

High-throughput

0.606

High

639635

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

2

4

High-throughput

0.606

High

639636

ZNT2
Proton-coupled zinc antiporter SLC30A2

2

4

High-throughput

0.606

High

503470

HSP7C
Heat shock cognate 71 kDa protein

2

6

Small-scale

0.584

High

639558

STAT1
Signal transducer and activator of transcription 1-alpha/beta

2

2

Small-scale

0.584

High

639625

TLCD1
TLC domain-containing protein 1

2

0

High-throughput

0.580

High

639640

TM147
BOS complex subunit TMEM147

2

0

High-throughput

0.580

High

639661

FAF1
FAS-associated factor 1

1

7

Small-scale

0.573

High

639622

TANK
TRAF family member-associated NF-kappa-B activator

2

1

Small-scale

0.563

High

639554

HSP74
Heat shock 70 kDa protein 4

1

7

Small-scale

0.561

High

639629

S39AD
Zinc transporter ZIP13

2

8

High-throughput

0.553

High

153874

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

4

High-throughput

0.536

High

255288

HIP1R
Huntingtin-interacting protein 1-related protein

1

5

High-throughput

0.536

High

639560

MTOR
Serine/threonine-protein kinase mTOR

1

10

High-throughput

0.536

High

639565

CTR2
Cationic amino acid transporter 2

1

3

High-throughput

0.536

High

639567

XPO2
Exportin-2

1

10

High-throughput

0.536

High

639583

EI2BA
Translation initiation factor eIF2B subunit alpha

1

2

High-throughput

0.536

High

639589

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

4

High-throughput

0.536

High

639601

NBEL2
Neurobeachin-like protein 2

1

3

High-throughput

0.536

High

639603

MON2
Protein MON2 homolog

1

8

High-throughput

0.536

High

639609

S39AB
Zinc transporter ZIP11

1

8

High-throughput

0.536

High

639611

F241A
Uncharacterized protein FAM241A

1

1

High-throughput

0.536

High

639614

CIP2A
Protein CIP2A

1

1

High-throughput

0.536

High

639615

GEMI5
Gem-associated protein 5

1

1

High-throughput

0.536

High

639623

TNPO1
Transportin-1

1

9

High-throughput

0.536

High

639624

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

13

High-throughput

0.536

High

639649

AT131
Endoplasmic reticulum transmembrane helix translocase

1

14

High-throughput

0.536

High

639656

ATX10
Ataxin-10

1

1

High-throughput

0.536

High

639658

HDAC6
Histone deacetylase 6

1

2

High-throughput

0.536

High

639669

TNPO3
Transportin-3

1

18

High-throughput

0.536

High

639671

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

8

High-throughput

0.536

High

116969

SGK1
Serine/threonine-protein kinase Sgk1

1

8

High-throughput

0.515

High

495467

THIO
Thioredoxin

1

1

High-throughput

0.515

High

610232

CBL
E3 ubiquitin-protein ligase CBL

1

10

Small-scale

0.515

High

622721

IL4RA
Interleukin-4 receptor subunit alpha

1

5

Small-scale

0.515

High

639549

CALR
Calreticulin

1

2

High-throughput

0.515

High

639563

JAK3
Tyrosine-protein kinase JAK3

1

20

Small-scale

0.515

High

639637

ERP44
Endoplasmic reticulum resident protein 44

1

3

High-throughput

0.515

High

639655

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

1

High-throughput

0.515

High

639568

GEMI4
Gem-associated protein 4

1

0

High-throughput

0.513

High

639571

COG7
Conserved oligomeric Golgi complex subunit 7

1

0

High-throughput

0.513

High

639602

DYM
Dymeclin

1

0

High-throughput

0.513

High

639630

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

High-throughput

0.513

High

639632

XPO6
Exportin-6

1

0

High-throughput

0.513

High

639657

NCDN
Neurochondrin

1

0

High-throughput

0.513

High

639663

EXOC7
Exocyst complex component 7

1

0

High-throughput

0.513

High

316305

TYDP2
Tyrosyl-DNA phosphodiesterase 2

1

2

Small-scale

0.504

High

523532

XRCC6
X-ray repair cross-complementing protein 6

1

1

Small-scale

0.501

High

524799

XRCC5
X-ray repair cross-complementing protein 5

1

1

Small-scale

0.501

High

639584

NCOA6
Nuclear receptor coactivator 6

1

2

Small-scale

0.501

High

603361

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.493

High

639556

RFC5
Replication factor C subunit 5

1

0

High-throughput

0.493

High

155533

TNPO2
Transportin-2

1

12

High-throughput

0.489

High

178112

IPO8
Importin-8

1

12

High-throughput

0.489

High

217776

ORC4
Origin recognition complex subunit 4

1

7

High-throughput

0.489

High

297155

IPO13
Importin-13

1

16

High-throughput

0.489

High

639555

PEX19
Peroxisomal biogenesis factor 19

1

1

High-throughput

0.489

High

639561

EI2BB
Translation initiation factor eIF2B subunit beta

1

2

High-throughput

0.489

High

639566

NUP98
Nuclear pore complex protein Nup98-Nup96

1

3

High-throughput

0.489

High

639582

ATR
Serine/threonine-protein kinase ATR

1

6

High-throughput

0.489

High

639587

KIF14
Kinesin-like protein KIF14

1

4

High-throughput

0.489

High

639591

SMN
Survival motor neuron protein

1

1

High-throughput

0.489

High

639594

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

1

5

High-throughput

0.489

High

639596

RN213
E3 ubiquitin-protein ligase RNF213

1

1

High-throughput

0.489

High

639598

TTI2
TELO2-interacting protein 2

1

1

High-throughput

0.489

High

639600

THADA
tRNA

1

1

High-throughput

0.489

High

639606

HOOK3
Protein Hook homolog 3

1

5

High-throughput

0.489

High

639610

STAG2
Cohesin subunit SA-2

1

1

High-throughput

0.489

High

639617

STAG1
Cohesin subunit SA-1

1

1

High-throughput

0.489

High

639620

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

7

High-throughput

0.489

High

639621

GCN1
Stalled ribosome sensor GCN1

1

7

High-throughput

0.489

High

639628

SAAL1
Protein SAAL1

1

1

High-throughput

0.489

High

639642

FACD2
Fanconi anemia group D2 protein

1

2

High-throughput

0.489

High

639643

XPO4
Exportin-4

1

6

High-throughput

0.489

High

639644

INT2
Integrator complex subunit 2

1

1

High-throughput

0.489

High

639645

HEAT1
HEAT repeat-containing protein 1

1

1

High-throughput

0.489

High

639646

REEP4
Receptor expression-enhancing protein 4

1

1

High-throughput

0.489

High

639648

XPO5
Exportin-5

1

13

High-throughput

0.489

High

639651

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

1

High-throughput

0.489

High

639659

EI2BD
Translation initiation factor eIF2B subunit delta

1

2

High-throughput

0.489

High

639660

IPO11
Importin-11

1

10

High-throughput

0.489

High

639672

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

8

High-throughput

0.489

High

639574

SUH
Recombining binding protein suppressor of hairless

1

0

Small-scale

0.480

High

639666

TR150
Thyroid hormone receptor-associated protein 3

1

0

Small-scale

0.480

High

158399

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

17

Small-scale

0.479

High

167474

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

18

Small-scale

0.479

High

174634

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.479

High

201756

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

10

Small-scale

0.479

High

203876

HTRA2
Serine protease HTRA2, mitochondrial

1

2

Small-scale

0.479

High

324237

BAG3
BAG family molecular chaperone regulator 3

1

3

High-throughput

0.479

High

639550

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

8

Small-scale

0.479

High

639559

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

5

Small-scale

0.479

High

639570

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

639572

CAV1
Caveolin-1

1

3

Small-scale

0.479

High

639573

REL
Proto-oncogene c-Rel

1

5

Small-scale

0.479

High

639580

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

4

Small-scale

0.479

High

639586

IMB1
Importin subunit beta-1

1

7

Small-scale

0.479

High

639607

STING
Stimulator of interferon genes protein

1

2

Small-scale

0.479

High

639627

RNF31
E3 ubiquitin-protein ligase RNF31

1

5

Small-scale

0.479

High

639634

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

2

High-throughput

0.479

High

639638

TRAF4
TNF receptor-associated factor 4

1

20

Small-scale

0.479

High

639650

DBLOH
Diablo IAP-binding mitochondrial protein

1

1

Small-scale

0.479

High

639654

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

1

6

Small-scale

0.479

High

639673

NEMO
NF-kappa-B essential modulator

1

12

Small-scale

0.479

High

639613

ZNT7
Zinc transporter 7

1

4

High-throughput

0.470

High

639619

S39A7
Zinc transporter SLC39A7

1

8

High-throughput

0.470

High

639667

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

2

High-throughput

0.470

High

133886

DDX3X
ATP-dependent RNA helicase DDX3X

1

0

High-throughput

0.458

High

515697

CD20
B-lymphocyte antigen CD20

1

0

Small-scale

0.458

High

603109

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

0

High-throughput

0.458

High

639604

AKNA
Microtubule organization protein AKNA

1

0

Small-scale

0.458

High

261406

NCOR1
Nuclear receptor corepressor 1

1

7

Small-scale

0.437

High

265393

KTNA1
Katanin p60 ATPase-containing subunit A1

1

5

High-throughput

0.437

High

639557

M3K8
Mitogen-activated protein kinase kinase kinase 8

1

6

Small-scale

0.437

High

639562

IMA5
Importin subunit alpha-5

1

4

Small-scale

0.437

High

596867

MAL
Myelin and lymphocyte protein

2

0

High-throughput

0.316

High

639588

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.316

High

639592

TM128
Transmembrane protein 128

2

0

High-throughput

0.316

High

639593

DB121
Beta-defensin 121

2

0

High-throughput

0.316

High

639599

TM107
Transmembrane protein 107

2

0

High-throughput

0.316

High

639626

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

0

High-throughput

0.316

High

639670

INSI2
Insulin-induced gene 2 protein

2

0

High-throughput

0.316

High

130024

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.279

Low

195884

TTI1
TELO2-interacting protein 1 homolog

1

0

High-throughput

0.279

Low

296871

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.279

Low

639575

NU160
Nuclear pore complex protein Nup160

1

0

High-throughput

0.279

Low

639579

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

0

High-throughput

0.279

Low

639585

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

High-throughput

0.279

Low

639605

GP180
Integral membrane protein GPR180

1

0

High-throughput

0.279

Low

639608

DAAF5
Dynein axonemal assembly factor 5

1

0

High-throughput

0.279

Low

639616

COG1
Conserved oligomeric Golgi complex subunit 1

1

0

High-throughput

0.279

Low

639618

GEMI6
Gem-associated protein 6

1

0

High-throughput

0.279

Low

639631

COG8
Conserved oligomeric Golgi complex subunit 8

1

0

High-throughput

0.279

Low

639639

LST8
Target of rapamycin complex subunit LST8

1

0

High-throughput

0.279

Low

639641

NUP85
Nuclear pore complex protein Nup85

1

0

High-throughput

0.279

Low

639647

COG4
Conserved oligomeric Golgi complex subunit 4

1

0

High-throughput

0.279

Low

639652

GEMI8
Gem-associated protein 8

1

0

High-throughput

0.279

Low

639662

COG5
Conserved oligomeric Golgi complex subunit 5

1

0

High-throughput

0.279

Low

639665

COG6
Conserved oligomeric Golgi complex subunit 6

1

0

High-throughput

0.279

Low

639564

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.269

Low

639590

B2LA1
Bcl-2-related protein A1

1

0

Small-scale

0.249

Low

639595

OBI1
ORC ubiquitin ligase 1

1

0

High-throughput

0.249

Low

639633

MYCBP
c-Myc-binding protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024