HitPredict

Interactor 1: K7EM38 (K7EM38)
Actin, cytoplasmic 2
Gene: ACTG1

Interactor 2: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Actin~Metallophos
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 133 Hs			1 327
+	Hs
		968244 ACTG_HUMAN (1-133): 2.4e-72: 222: 84.08		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		952711 ACTB_HUMAN (1-133): 1.88e-71: 220: 81.53		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		968247 ACTC_HUMAN (2-133): 2.81e-69: 214: 78.21		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		968248 ACTS_HUMAN (2-133): 1.93e-69: 214: 78.21		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Mm
		968069 ACTG_MOUSE (1-133): 2.4e-72: 222: 84.08		PP1A_MOUSE (1-326): 0: 576: 88.49
+	Hs
		952710 ACTB_HUMAN (1-133): 1.88e-71: 220: 81.53		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Hs
		786528 ACTG_HUMAN (1-133): 2.4e-72: 222: 84.08		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		967658 ACTS_HUMAN (2-133): 1.93e-69: 214: 78.21		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Hs
		786475 ACTB_HUMAN (1-133): 1.88e-71: 220: 81.53		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		786532 ACTC_HUMAN (2-133): 2.81e-69: 214: 78.21		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Sc
		743265 ACT_YEAST (1-133): 6.2e-71: 218: 78.98		PP12_YEAST (1-308): 0: 547: 81.49