Protein: AF9
Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3)

Gene: AF9, MLLT3
Organism: Homo sapiens
Interactions: 86
UniProt ID: P42568

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

788015

AFF1
AF4/FMR2 family member 1

6

8

Small-scale

0.950

High

788073

AFF4
AF4/FMR2 family member 4

6

11

Small-scale

0.946

High

788026

ENL
Protein ENL

6

10

Small-scale

0.940

High

788014

CDK9
Cyclin-dependent kinase 9

12

8

Small-scale

0.759

High

788053

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

11

4

Small-scale

0.759

High

788016

AFF3
AF4/FMR2 family member 3

2

10

Small-scale

0.754

High

788043

BCOR
BCL-6 corepressor

5

13

Small-scale

0.724

High

788058

EAF1
ELL-associated factor 1

5

1

Small-scale

0.718

High

788066

ELL3
RNA polymerase II elongation factor ELL3

5

10

Small-scale

0.712

High

788019

ELL
RNA polymerase II elongation factor ELL

5

10

Small-scale

0.709

High

130146

ELL2
RNA polymerase II elongation factor ELL2

4

12

Small-scale

0.694

High

788018

AF17
Protein AF-17

3

7

Small-scale

0.675

High

788055

EDA
Ectodysplasin-A

3

1

High-throughput

0.667

High

788065

DEN2D
DENN domain-containing protein 2D

3

1

High-throughput

0.667

High

236711

CCNT1
Cyclin-T1

3

4

Small-scale

0.656

High

788054

APBP2
Amyloid protein-binding protein 2

3

0

High-throughput

0.639

High

788069

EXOS3
Exosome complex component RRP40

3

0

High-throughput

0.638

High

204627

E41L2
Band 4.1-like protein 2

2

11

High-throughput

0.628

High

600947

MK
Midkine

2

1

High-throughput

0.628

High

685829

ARRB2
Beta-arrestin-2

2

2

High-throughput

0.628

High

788012

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

1

High-throughput

0.628

High

788052

BPIB1
BPI fold-containing family B member 1

2

1

High-throughput

0.628

High

788068

E41L5
Band 4.1-like protein 5

2

13

High-throughput

0.628

High

788074

E41L3
Band 4.1-like protein 3

2

12

High-throughput

0.628

High

788011

AF9
Protein AF-9

1

12

High-throughput

0.621

High

237382

CCNT2
Cyclin-T2

2

4

Small-scale

0.611

High

788017

AF10
Protein AF-10

2

8

Small-scale

0.611

High

788062

PCGF1
Polycomb group RING finger protein 1

2

11

Small-scale

0.611

High

788037

VAX1
Ventral anterior homeobox 1

2

2

High-throughput

0.606

High

788070

ALKB4
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4

3

1

Small-scale

0.604

High

132110

PESC
Pescadillo homolog

2

0

High-throughput

0.602

High

788024

H33
Histone H3.3

1

16

Small-scale

0.586

High

788027

KMT2A
Histone-lysine N-methyltransferase 2A

2

9

Small-scale

0.584

High

788044

ZN572
Zinc finger protein 572

2

0

High-throughput

0.580

High

788051

CAMKV
CaM kinase-like vesicle-associated protein

2

2

High-throughput

0.574

High

788075

SNX24
Sorting nexin-24

2

2

High-throughput

0.574

High

788025

CDK6
Cyclin-dependent kinase 6

1

5

Small-scale

0.569

High

538139

ENPL
Endoplasmin

1

5

Small-scale

0.561

High

788067

CBX8
Chromobox protein homolog 8

1

7

Small-scale

0.561

High

788023

H31
Histone H3.1

1

16

Small-scale

0.550

High

788022

EF1A1
Elongation factor 1-alpha 1

1

3

High-throughput

0.541

High

788030

MCM6
DNA replication licensing factor MCM6

1

1

High-throughput

0.541

High

788036

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

Small-scale

0.536

High

313402

MED26
Mediator of RNA polymerase II transcription subunit 26

1

2

High-throughput

0.536

High

788020

FGF12
Fibroblast growth factor 12

1

2

High-throughput

0.536

High

788021

SKP1
S-phase kinase-associated protein 1

1

1

Small-scale

0.536

High

788032

RASA2
Ras GTPase-activating protein 2

1

2

High-throughput

0.536

High

788040

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

1

1

High-throughput

0.536

High

788048

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

5

High-throughput

0.536

High

788056

FGF11
Fibroblast growth factor 11

1

2

High-throughput

0.536

High

788059

CEP89
Centrosomal protein of 89 kDa

1

7

High-throughput

0.536

High

788061

PLCD4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4

1

5

High-throughput

0.536

High

788064

E41L1
Band 4.1-like protein 1

1

12

High-throughput

0.536

High

788013

NRIP1
Nuclear receptor-interacting protein 1

1

0

High-throughput

0.518

High

788035

RBM48
RNA-binding protein 48

1

0

High-throughput

0.518

High

788033

RN151
RING finger protein 151

1

0

High-throughput

0.513

High

788071

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.513

High

788072

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.513

High

394275

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

788042

CDC73
Parafibromin

1

3

Small-scale

0.500

High

597372

PTN
Pleiotrophin

1

1

High-throughput

0.494

High

788050

SYT2
Synaptotagmin-2

1

3

High-throughput

0.489

High

116981

SGK1
Serine/threonine-protein kinase Sgk1

1

0

Small-scale

0.480

High

162476

XPO1
Exportin-1

1

5

High-throughput

0.479

High

262384

TULP3
Tubby-related protein 3

1

1

High-throughput

0.479

High

531063

EF2
Elongation factor 2

1

1

Small-scale

0.479

High

569336

CEBPB
CCAAT/enhancer-binding protein beta

1

6

High-throughput

0.479

High

750161

COIL
Coilin

1

2

High-throughput

0.479

High

788028

ACACA
Acetyl-CoA carboxylase 1

1

1

Small-scale

0.479

High

788029

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

6

High-throughput

0.479

High

788031

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

3

Small-scale

0.479

High

788041

NIPBL
Nipped-B-like protein

1

5

Small-scale

0.479

High

788047

CCAR2
Cell cycle and apoptosis regulator protein 2

1

1

Small-scale

0.479

High

788049

PAF1
RNA polymerase II-associated factor 1 homolog

1

1

Small-scale

0.479

High

788057

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

3

Small-scale

0.479

High

788060

RING2
E3 ubiquitin-protein ligase RING2

1

12

Small-scale

0.479

High

788038

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.460

High

788039

RIF1
Telomere-associated protein RIF1

1

7

High-throughput

0.457

High

788076

TRRAP
Transformation/transcription domain-associated protein

1

6

Small-scale

0.445

High

788046

FAM9A
Protein FAM9A

5

0

High-throughput

0.374

High

788034

MIIP
Migration and invasion-inhibitory protein

3

0

High-throughput

0.346

High

788045

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.279

Low

788063

SMOC1
SPARC-related modular calcium-binding protein 1

1

0

High-throughput

0.279

Low

788077

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.279

Low

483680

CT456
Cancer/testis antigen family 45 member A6

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024