Protein: ID1
DNA-binding protein inhibitor ID-1 (Class B basic helix-loop-helix protein 24) (bHLHb24) (Inhibitor of DNA binding 1) (Inhibitor of differentiation 1)

Gene: ID1
Organism: Homo sapiens
Interactions: 74
UniProt ID: P41134

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001525 - angiogenesis
GO:0001886 - endothelial cell morphogenesis
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

587424

TFE2
Transcription factor E2-alpha

8

20

Small-scale

0.971

High

587019

ITF2
Transcription factor 4

8

20

Small-scale

0.967

High

581630

MYOD1
Myoblast determination protein 1

7

13

Small-scale

0.957

High

832326

HTF4
Transcription factor 12

6

20

Small-scale

0.941

High

561208

MYF5
Myogenic factor 5

3

17

Small-scale

0.845

High

581756

MYOG
Myogenin

2

19

High-throughput

0.794

High

65872

MSGN1
Mesogenin-1

2

16

High-throughput

0.783

High

832333

ASCL3
Achaete-scute homolog 3

2

20

High-throughput

0.783

High

371371

MYC
Myc proto-oncogene protein

2

2

High-throughput

0.754

High

832304

HEN2
Helix-loop-helix protein 2

1

20

High-throughput

0.691

High

832315

ASCL4
Achaete-scute homolog 4

1

20

High-throughput

0.691

High

832324

PDLI5
PDZ and LIM domain protein 5

1

2

Small-scale

0.647

High

832297

PSMD4
26S proteasome non-ATPase regulatory subunit 4

2

1

Small-scale

0.631

High

832332

SMUF2
E3 ubiquitin-protein ligase SMURF2

2

3

Small-scale

0.624

High

558966

LYL1
Protein lyl-1

1

20

High-throughput

0.618

High

832295

NKX25
Homeobox protein Nkx-2.5

1

2

Small-scale

0.618

High

832338

DP13A
DCC-interacting protein 13-alpha

2

1

High-throughput

0.594

High

832339

FZR1
Fizzy-related protein homolog

2

4

Small-scale

0.584

High

117291

K7EMM4
Transcription factor E2-alpha

1

20

High-throughput

0.575

High

168648

CSKP
Peripheral plasma membrane protein CASK

1

1

Small-scale

0.573

High

832305

CAV1
Caveolin-1

1

0

Small-scale

0.561

High

832294

GATA4
Transcription factor GATA-4

1

2

Small-scale

0.561

High

832300

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

Small-scale

0.561

High

832322

TRI63
E3 ubiquitin-protein ligase TRIM63

1

1

High-throughput

0.541

High

832331

TRI55
Tripartite motif-containing protein 55

1

1

High-throughput

0.541

High

832344

NEMO
NF-kappa-B essential modulator

1

1

High-throughput

0.541

High

832314

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

1

High-throughput

0.536

High

832320

REQU
Zinc finger protein ubi-d4

1

1

High-throughput

0.536

High

832330

MKNK1
MAP kinase-interacting serine/threonine-protein kinase 1

1

2

High-throughput

0.536

High

832341

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

1

High-throughput

0.536

High

832316

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

2

High-throughput

0.515

High

297493

PIAS1
E3 SUMO-protein ligase PIAS1

1

0

High-throughput

0.513

High

832293

BUD31
Protein BUD31 homolog

1

0

High-throughput

0.513

High

832298

STXB1
Syntaxin-binding protein 1

1

0

High-throughput

0.513

High

832301

TXN4A
Thioredoxin-like protein 4A

1

0

High-throughput

0.513

High

832317

THOC6
THO complex subunit 6

1

0

High-throughput

0.513

High

832318

CHD1L
Chromodomain-helicase-DNA-binding protein 1-like

1

0

High-throughput

0.513

High

832323

SGF29
SAGA-associated factor 29

1

0

High-throughput

0.513

High

832325

HEXI2
Protein HEXIM2

1

0

High-throughput

0.513

High

832335

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.513

High

216388

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

2

High-throughput

0.508

High

442255

GELS
Gelsolin

1

0

High-throughput

0.493

High

702427

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.493

High

832303

EM55
55 kDa erythrocyte membrane protein

1

1

High-throughput

0.489

High

507640

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

832337

DNM3L
DNA

1

0

Small-scale

0.480

High

138001

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

2

Small-scale

0.479

High

822497

VHL
von Hippel-Lindau disease tumor suppressor

1

2

Small-scale

0.479

High

828182

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

2

Small-scale

0.479

High

832299

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

1

Small-scale

0.479

High

832302

SMAD3
Mothers against decapentaplegic homolog 3

1

1

Small-scale

0.479

High

832307

CDC20
Cell division cycle protein 20 homolog

1

6

Small-scale

0.479

High

832308

SMAD4
Mothers against decapentaplegic homolog 4

1

1

Small-scale

0.479

High

832309

SQSTM
Sequestosome-1

1

1

Small-scale

0.479

High

832310

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

1

Small-scale

0.479

High

832311

ELOC
Elongin-C

1

2

Small-scale

0.479

High

832313

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

2

Small-scale

0.479

High

832327

DNJC2
DnaJ homolog subfamily C member 2

1

1

Small-scale

0.479

High

832334

RASF1
Ras association domain-containing protein 1

1

1

Small-scale

0.479

High

650075

FGFR3
Fibroblast growth factor receptor 3

1

1

High-throughput

0.470

High

593041

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

Small-scale

0.458

High

652467

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

0

Small-scale

0.458

High

832306

FOXO1
Forkhead box protein O1

1

0

Small-scale

0.458

High

832319

WDR48
WD repeat-containing protein 48

1

0

Small-scale

0.458

High

832321

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

Small-scale

0.458

High

832342

TRAF6
TNF receptor-associated factor 6

1

0

Small-scale

0.458

High

832328

COCA1

1

1

High-throughput

0.437

High

94474

D6RGG3

1

1

High-throughput

0.407

High

832296

COPB
Coatomer subunit beta

1

0

High-throughput

0.282

High

832312

PSMD5
26S proteasome non-ATPase regulatory subunit 5

1

0

High-throughput

0.279

Low

832329

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.279

Low

832336

B4GT7
Beta-1,4-galactosyltransferase 7

1

0

High-throughput

0.279

Low

832340

CCDC9
Coiled-coil domain-containing protein 9

1

0

High-throughput

0.279

Low

832343

Q9Y649
GW128

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025