Protein: ANXA5
Annexin A5 (Anchorin CII) (Annexin V) (Annexin-5) (Calphobindin I) (CPB-I) (Endonexin II) (Lipocortin V) (Placental anticoagulant protein 4) (PP4) (Placental anticoagulant protein I) (PAP-I) (Thromboplastin inhibitor) (Vascular anticoagulant-alpha) (VAC-alpha)

Gene: ANXA5
Organism: Homo sapiens
Interactions: 173
UniProt ID: P08758

Gene Ontology (top 5):
GO:0001786 - phosphatidylserine binding
GO:0004859 - phospholipase inhibitor activity
GO:0005509 - calcium ion binding
GO:0005543 - phospholipid binding
GO:0005544 - calcium-dependent phospholipid binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

444918

LRC15
Leucine-rich repeat-containing protein 15

3

0

High-throughput

0.629

High

427412

ANXA2
Annexin A2

1

6

High-throughput

0.618

High

444941

CRNN
Cornulin

1

12

High-throughput

0.618

High

444819

CFTR
Cystic fibrosis transmembrane conductance regulator

2

4

Small-scale

0.611

High

373557

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

8

High-throughput

0.584

High

444843

PDIA3
Protein disulfide-isomerase A3

2

4

High-throughput

0.584

High

444860

YAP1
Transcriptional coactivator YAP1

2

11

High-throughput

0.584

High

444868

TERA
Transitional endoplasmic reticulum ATPase

2

6

High-throughput

0.584

High

444817

FGR
Tyrosine-protein kinase Fgr

2

1

High-throughput

0.571

High

444818

TAU
Microtubule-associated protein tau

2

4

Small-scale

0.571

High

444875

RAC1
Ras-related C3 botulinum toxin substrate 1

2

7

High-throughput

0.571

High

444894

KPCD1
Serine/threonine-protein kinase D1

2

6

High-throughput

0.571

High

444915

DOCK8
Dedicator of cytokinesis protein 8

2

4

High-throughput

0.571

High

444929

SH3G3
Endophilin-A3

2

4

High-throughput

0.571

High

444829

ITB5
Integrin beta-5

1

1

Small-scale

0.561

High

180968

GSC2
Homeobox protein goosecoid-2

2

1

High-throughput

0.553

High

444867

TERF1
Telomeric repeat-binding factor 1

1

4

High-throughput

0.541

High

444940

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

2

High-throughput

0.541

High

153071

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

7

High-throughput

0.536

High

170220

TIF1A
Transcription intermediary factor 1-alpha

1

11

High-throughput

0.536

High

201183

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

2

High-throughput

0.536

High

296503

KPCD3
Serine/threonine-protein kinase D3

1

6

High-throughput

0.536

High

337808

EGFR
Epidermal growth factor receptor

1

10

High-throughput

0.536

High

444825

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

4

High-throughput

0.536

High

444827

H2AX
Histone H2AX

1

7

High-throughput

0.536

High

444844

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

1

Small-scale

0.536

High

444858

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

2

High-throughput

0.536

High

444859

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

7

High-throughput

0.536

High

444898

MYLK
Myosin light chain kinase, smooth muscle

1

1

High-throughput

0.536

High

444917

NEK7
Serine/threonine-protein kinase Nek7

1

6

High-throughput

0.536

High

444922

SGK3
Serine/threonine-protein kinase Sgk3

1

6

High-throughput

0.536

High

444932

KPCD2
Serine/threonine-protein kinase D2

1

6

High-throughput

0.536

High

444850

VGFR2
Vascular endothelial growth factor receptor 2

1

1

Small-scale

0.527

High

444930

TINF2
TERF1-interacting nuclear factor 2

1

3

High-throughput

0.518

High

444851

FDFT
Squalene synthase

1

0

High-throughput

0.518

High

397733

ISG15
Ubiquitin-like protein ISG15

1

5

High-throughput

0.515

High

281511

WFS1
Wolframin

1

1

High-throughput

0.515

High

388167

HSPB1
Heat shock protein beta-1

1

3

High-throughput

0.515

High

444923

OPTN
Optineurin

1

14

High-throughput

0.515

High

444823

IRF2
Interferon regulatory factor 2

1

0

High-throughput

0.513

High

444832

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.513

High

358589

CO2A1
Collagen alpha-1(II) chain

1

4

Small-scale

0.501

High

393969

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

444879

COAA1

1

5

Small-scale

0.501

High

444897

TERF2
Telomeric repeat-binding factor 2

1

4

High-throughput

0.494

High

168101

TBX3
T-box transcription factor TBX3

1

0

High-throughput

0.493

High

444916

OR1M1
Olfactory receptor 1M1

1

0

High-throughput

0.493

High

444926

LMTK3
Serine/threonine-protein kinase LMTK3

1

8

High-throughput

0.489

High

444936

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

4

High-throughput

0.489

High

444853

INGR2
Interferon gamma receptor 2

1

1

Small-scale

0.483

High

117338

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

1

High-throughput

0.479

High

121085

LEG8
Galectin-8

1

10

Small-scale

0.479

High

168713

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

1

Small-scale

0.479

High

214045

SPOP
Speckle-type POZ protein

1

4

High-throughput

0.479

High

225484

PCDH7
Protocadherin-7

1

2

High-throughput

0.479

High

242657

IF2P
Eukaryotic translation initiation factor 5B

1

1

High-throughput

0.479

High

254863

CPNE3
Copine-3

1

3

High-throughput

0.479

High

278719

DNJC8
DnaJ homolog subfamily C member 8

1

1

High-throughput

0.479

High

282489

RNF8
E3 ubiquitin-protein ligase RNF8

1

8

High-throughput

0.479

High

301561

TRI37
E3 ubiquitin-protein ligase TRIM37

1

14

High-throughput

0.479

High

324182

BAG3
BAG family molecular chaperone regulator 3

1

4

High-throughput

0.479

High

329264

AGR2
Anterior gradient protein 2 homolog

1

5

High-throughput

0.479

High

336318

SODC
Superoxide dismutase [Cu-Zn]

1

3

High-throughput

0.479

High

340357

PGK1
Phosphoglycerate kinase 1

1

1

High-throughput

0.479

High

345742

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.479

High

384131

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.479

High

411280

INSR
Insulin receptor

1

9

High-throughput

0.479

High

444821

PLST
Plastin-3

1

1

High-throughput

0.479

High

444824

ENPL
Endoplasmin

1

3

High-throughput

0.479

High

444830

PGAM1
Phosphoglycerate mutase 1

1

1

High-throughput

0.479

High

444833

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

5

High-throughput

0.479

High

444834

CDK2
Cyclin-dependent kinase 2

1

4

High-throughput

0.479

High

444835

TNR6
Tumor necrosis factor receptor superfamily member 6

1

2

High-throughput

0.479

High

444837

HMGB2
High mobility group protein B2

1

9

High-throughput

0.479

High

444839

CALR
Calreticulin

1

1

High-throughput

0.479

High

444840

TKT
Transketolase

1

2

High-throughput

0.479

High

444842

PEBP1
Phosphatidylethanolamine-binding protein 1

1

4

High-throughput

0.479

High

444848

FBN1
Fibrillin-1 [Cleaved into: Asprosin]

1

2

Small-scale

0.479

High

444849

FUS
RNA-binding protein FUS

1

3

High-throughput

0.479

High

444852

BRCA1
Breast cancer type 1 susceptibility protein

1

6

High-throughput

0.479

High

444854

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

2

High-throughput

0.479

High

444855

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

444856

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

444861

PA24A
Cytosolic phospholipase A2

1

4

Small-scale

0.479

High

444862

SOX2
Transcription factor SOX-2

1

6

High-throughput

0.479

High

444865

CDK7
Cyclin-dependent kinase 7

1

4

High-throughput

0.479

High

444871

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

4

High-throughput

0.479

High

444872

CH10
10 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.479

High

444874

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

6

High-throughput

0.479

High

444877

BASP1
Brain acid soluble protein 1

1

1

High-throughput

0.479

High

444878

HSF1
Heat shock factor protein 1

1

3

High-throughput

0.479

High

444882

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

1

5

Small-scale

0.479

High

444884

TRI26
Tripartite motif-containing protein 26

1

4

Small-scale

0.479

High

444885

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

2

High-throughput

0.479

High

444886

NFX1
Transcriptional repressor NF-X1

1

1

High-throughput

0.479

High

444887

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

1

High-throughput

0.479

High

444888

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

444889

CUL4A
Cullin-4A

1

11

High-throughput

0.479

High

444890

DX39B
Spliceosome RNA helicase DDX39B

1

4

High-throughput

0.479

High

444891

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

12

High-throughput

0.479

High

444892

CUL7
Cullin-7

1

2

High-throughput

0.479

High

444893

EMC2
ER membrane protein complex subunit 2

1

5

High-throughput

0.479

High

444901

TET5C
Terminal nucleotidyltransferase 5C

1

1

High-throughput

0.479

High

444902

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

444903

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.479

High

444905

SND1
Staphylococcal nuclease domain-containing protein 1

1

2

High-throughput

0.479

High

444907

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

7

High-throughput

0.479

High

444908

ARMC8
Armadillo repeat-containing protein 8

1

1

High-throughput

0.479

High

444910

RPTOR
Regulatory-associated protein of mTOR

1

3

High-throughput

0.479

High

444911

EMC5
ER membrane protein complex subunit 5

1

3

High-throughput

0.479

High

444912

EMC1
ER membrane protein complex subunit 1

1

3

High-throughput

0.479

High

444913

CGAS
Cyclic GMP-AMP synthase

1

2

High-throughput

0.479

High

444919

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.479

High

444920

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

10

High-throughput

0.479

High

444921

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

2

High-throughput

0.479

High

444924

GCP3
Gamma-tubulin complex component 3

1

1

High-throughput

0.479

High

444925

ASB9
Ankyrin repeat and SOCS box protein 9

1

3

High-throughput

0.479

High

444931

DOCK9
Dedicator of cytokinesis protein 9

1

4

High-throughput

0.479

High

444933

DDX24
ATP-dependent RNA helicase DDX24

1

4

High-throughput

0.479

High

444934

Q9H4D1
Protein kinase

1

1

High-throughput

0.479

High

444935

NMRL1
NmrA-like family domain-containing protein 1

1

1

High-throughput

0.479

High

444937

ARGAL
Rho guanine nucleotide exchange factor 10-like protein

1

3

High-throughput

0.479

High

444942

HDAC6
Histone deacetylase 6

1

5

High-throughput

0.479

High

444944

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.479

High

444948

LAMC3
Laminin subunit gamma-3

1

0

High-throughput

0.460

High

135344

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

0

High-throughput

0.458

High

210439

ZN207
BUB3-interacting and GLEBS motif-containing protein ZNF207

1

0

High-throughput

0.458

High

262678

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

337050

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

High-throughput

0.458

High

396868

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.458

High

417476

PYGL
Glycogen phosphorylase, liver form

1

0

High-throughput

0.458

High

417671

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

430011

PROF1
Profilin-1

1

0

High-throughput

0.458

High

444822

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.458

High

444828

STMN1
Stathmin

1

0

High-throughput

0.458

High

444831

PTMS
Parathymosin

1

0

High-throughput

0.458

High

444841

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

444863

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.458

High

444870

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

444881

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.458

High

444895

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.458

High

444900

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.458

High

444927

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.458

High

444928

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

444939

SIAS
Sialic acid synthase

1

0

High-throughput

0.458

High

444945

PA2G4
Proliferation-associated protein 2G4

1

0

High-throughput

0.458

High

444946

WBP11
WW domain-binding protein 11

1

0

High-throughput

0.458

High

444846

BMI1
Polycomb complex protein BMI-1

1

9

High-throughput

0.445

High

444869

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.445

High

444904

NEK10
Serine/threonine-protein kinase Nek10

1

5

High-throughput

0.445

High

444914

POC5
Centrosomal protein POC5

1

1

Small-scale

0.445

High

444880

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

0

High-throughput

0.438

High

243822

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.437

High

441213

RU2B
U2 small nuclear ribonucleoprotein B''

1

3

High-throughput

0.437

High

444820

PDIA4
Protein disulfide-isomerase A4

1

4

High-throughput

0.437

High

444826

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.437

High

444836

U2AF2
Splicing factor U2AF 65 kDa subunit

1

6

High-throughput

0.437

High

444838

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

444847

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

444857

BCL6
B-cell lymphoma 6 protein

1

3

High-throughput

0.437

High

444873

SUMO2
Small ubiquitin-related modifier 2

1

5

High-throughput

0.437

High

444883

SF3A3
Splicing factor 3A subunit 3

1

1

High-throughput

0.437

High

444899

EZH2
Histone-lysine N-methyltransferase EZH2

1

5

High-throughput

0.437

High

444906

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.437

High

444909

TRI59
Tripartite motif-containing protein 59

1

7

Small-scale

0.437

High

444947

AAR2
Protein AAR2 homolog

1

2

High-throughput

0.437

High

444864

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.373

High

444845

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.279

Low

444938

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

1

0

High-throughput

0.279

Low

444866

RM12
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.249

Low

444896

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.249

Low

444943

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.249

Low

444876

SPT4H
Transcription elongation factor SPT4

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024