Protein: RBM10
RNA-binding protein 10 (G patch domain-containing protein 9) (RNA-binding motif protein 10) (RNA-binding protein S1-1) (S1-1)

Gene: RBM10
Organism: Homo sapiens
Interactions: 248
UniProt ID: P98175

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

958097

DDX17
Probable ATP-dependent RNA helicase DDX17

5

9

High-throughput

0.922

High

958037

SF3B4
Splicing factor 3B subunit 4

4

20

High-throughput

0.911

High

958150

PTBP2
Polypyrimidine tract-binding protein 2

4

18

High-throughput

0.899

High

958077

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

3

15

High-throughput

0.861

High

643479

PTBP1
Polypyrimidine tract-binding protein 1

3

18

High-throughput

0.852

High

641719

U2AF2
Splicing factor U2AF 65 kDa subunit

2

20

High-throughput

0.831

High

958071

RB12B
RNA-binding protein 12B

3

19

High-throughput

0.825

High

958003

RBM10
RNA-binding protein 10

2

18

High-throughput

0.817

High

195402

DHX15
ATP-dependent RNA helicase DHX15

2

10

High-throughput

0.808

High

165448

SR140
U2 snRNP-associated SURP motif-containing protein

1

18

High-throughput

0.740

High

958039

SF3A1
Splicing factor 3A subunit 1

1

6

High-throughput

0.740

High

958093

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

13

High-throughput

0.740

High

934097

CSK21
Casein kinase II subunit alpha

1

13

High-throughput

0.735

High

958036

RBY1F
RNA-binding motif protein, Y chromosome, family 1 member F/J

1

19

High-throughput

0.698

High

235800

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

18

High-throughput

0.691

High

268677

SF3B1
Splicing factor 3B subunit 1

1

1

High-throughput

0.691

High

586685

CSK22
Casein kinase II subunit alpha'

1

11

High-throughput

0.691

High

616253

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.691

High

958044

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

13

High-throughput

0.691

High

958106

SPF45
Splicing factor 45

1

20

High-throughput

0.691

High

958123

PRD14
PR domain zinc finger protein 14

3

2

High-throughput

0.667

High

958144

THAP1
THAP domain-containing protein 1

3

1

High-throughput

0.667

High

958012

TADBP
TAR DNA-binding protein 43

1

19

High-throughput

0.665

High

571402

DDX5
Probable ATP-dependent RNA helicase DDX5

1

8

High-throughput

0.656

High

878640

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

18

High-throughput

0.656

High

958006

U2AF1
Splicing factor U2AF 35 kDa subunit

1

2

High-throughput

0.656

High

958014

SRSF6
Serine/arginine-rich splicing factor 6

1

19

High-throughput

0.656

High

958041

SF01
Splicing factor 1

1

9

High-throughput

0.656

High

958117

RBM4
RNA-binding protein 4

1

20

High-throughput

0.656

High

958137

UBQL4
Ubiquilin-4

1

8

High-throughput

0.656

High

338282

EGFR
Epidermal growth factor receptor

3

5

Small-scale

0.640

High

386527

P53
Cellular tumor antigen p53

3

6

Small-scale

0.640

High

958154

PRP19
Pre-mRNA-processing factor 19

2

11

High-throughput

0.631

High

446588

SNRPA
U1 small nuclear ribonucleoprotein A

1

18

High-throughput

0.621

High

958018

SF3B2
Splicing factor 3B subunit 2

1

1

High-throughput

0.621

High

958088

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

20

High-throughput

0.621

High

958109

RBM14
RNA-binding protein 14

1

19

High-throughput

0.621

High

958142

RBM12
RNA-binding protein 12

1

19

High-throughput

0.621

High

958158

RBM7
RNA-binding protein 7

1

19

High-throughput

0.621

High

958070

CCAR1
Cell division cycle and apoptosis regulator protein 1

2

5

High-throughput

0.620

High

128994

PLK4
Serine/threonine-protein kinase PLK4

1

9

High-throughput

0.618

High

851451

NEK4
Serine/threonine-protein kinase Nek4

1

8

High-throughput

0.618

High

148683

CTRO
Citron Rho-interacting kinase

1

10

High-throughput

0.618

High

227176

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.618

High

325690

LATS1
Serine/threonine-protein kinase LATS1

1

7

High-throughput

0.618

High

331788

NSD2
Histone-lysine N-methyltransferase NSD2

1

7

Small-scale

0.618

High

442069

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

18

High-throughput

0.618

High

453290

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

20

High-throughput

0.618

High

726748

FUS
RNA-binding protein FUS

1

20

High-throughput

0.618

High

757569

IF4A3
Eukaryotic initiation factor 4A-III

1

19

High-throughput

0.618

High

801856

RECQ1
ATP-dependent DNA helicase Q1

1

13

High-throughput

0.618

High

815228

TISD
mRNA decay activator protein ZFP36L2

1

5

High-throughput

0.618

High

841163

CDK7
Cyclin-dependent kinase 7

1

6

High-throughput

0.618

High

958009

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

14

High-throughput

0.618

High

958021

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

11

High-throughput

0.618

High

958024

RBM39
RNA-binding protein 39

1

20

High-throughput

0.618

High

958025

DHX8
ATP-dependent RNA helicase DHX8

1

14

High-throughput

0.618

High

958029

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

14

High-throughput

0.618

High

958038

SF3A2
Splicing factor 3A subunit 2

1

8

High-throughput

0.618

High

958042

ELAV1
ELAV-like protein 1

1

20

High-throughput

0.618

High

958089

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

1

4

Small-scale

0.618

High

958096

RBP56
TATA-binding protein-associated factor 2N

1

12

High-throughput

0.618

High

958098

CELF1
CUGBP Elav-like family member 1

1

20

High-throughput

0.618

High

958116

DDX23
Probable ATP-dependent RNA helicase DDX23

1

13

High-throughput

0.618

High

958131

RC3H2
Roquin-2

1

17

High-throughput

0.618

High

958148

UBQL2
Ubiquilin-2

1

6

High-throughput

0.618

High

958015

KLF1
Krueppel-like factor 1

2

6

High-throughput

0.606

High

958103

MBD6
Methyl-CpG-binding domain protein 6

2

3

High-throughput

0.606

High

958128

ZN408
Zinc finger protein 408

2

2

High-throughput

0.606

High

958132

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

2

1

High-throughput

0.606

High

958139

ZN275
Zinc finger protein 275

2

1

High-throughput

0.606

High

899459

MGN
Protein mago nashi homolog

1

0

High-throughput

0.586

High

244286

BRD4
Bromodomain-containing protein 4

2

3

High-throughput

0.584

High

487337

ANDR
Androgen receptor

2

20

High-throughput

0.584

High

552500

RFA2
Replication protein A 32 kDa subunit

2

7

High-throughput

0.584

High

650964

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

4

High-throughput

0.584

High

720235

RFA3
Replication protein A 14 kDa subunit

2

4

High-throughput

0.584

High

808514

YAP1
Transcriptional coactivator YAP1

2

15

High-throughput

0.584

High

917114

H4
Histone H4

2

3

High-throughput

0.584

High

958083

BAHD1
Bromo adjacent homology domain-containing 1 protein

2

0

High-throughput

0.580

High

958086

ZN526
Zinc finger protein 526

2

0

High-throughput

0.580

High

958110

ZN317
Zinc finger protein 317

2

0

High-throughput

0.580

High

853858

NCBP2
Nuclear cap-binding protein subunit 2

1

17

High-throughput

0.575

High

958130

LN28A
Protein lin-28 homolog A

1

17

High-throughput

0.575

High

958149

DDX41
Probable ATP-dependent RNA helicase DDX41

1

9

High-throughput

0.575

High

448614

RU1C
U1 small nuclear ribonucleoprotein C

1

3

High-throughput

0.573

High

958011

RED
Protein Red

1

1

High-throughput

0.573

High

958069

SUGP1
SURP and G-patch domain-containing protein 1

1

10

High-throughput

0.573

High

346528

MYC
Myc proto-oncogene protein

2

18

High-throughput

0.571

High

958005

MDM2
E3 ubiquitin-protein ligase Mdm2

1

2

Small-scale

0.561

High

159193

CSKP
Peripheral plasma membrane protein CASK

1

2

High-throughput

0.555

High

958099

GPKOW
G-patch domain and KOW motifs-containing protein

1

0

High-throughput

0.549

High

958007

TLE5
TLE family member 5

1

0

High-throughput

0.549

High

196596

ZBT24
Zinc finger and BTB domain-containing protein 24

1

1

High-throughput

0.541

High

878298

NH2L1
NHP2-like protein 1

1

2

High-throughput

0.541

High

958052

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

1

9

High-throughput

0.541

High

958060

HAKAI
E3 ubiquitin-protein ligase Hakai

1

2

High-throughput

0.541

High

117662

MYO1C
Unconventional myosin-Ic

1

3

High-throughput

0.536

High

508454

TOP1
DNA topoisomerase 1

1

3

High-throughput

0.536

High

685906

ARRB2
Beta-arrestin-2

1

4

High-throughput

0.536

High

804206

NOTC1
Neurogenic locus notch homolog protein 1

1

2

High-throughput

0.536

High

827165

ARRB1
Beta-arrestin-1

1

4

High-throughput

0.536

High

958008

SSRP1
FACT complex subunit SSRP1

1

5

High-throughput

0.536

High

958019

SNW1
SNW domain-containing protein 1

1

4

High-throughput

0.536

High

958020

CUL3
Cullin-3

1

18

High-throughput

0.536

High

958063

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

8

High-throughput

0.536

High

958152

AGO2
Protein argonaute-2

1

14

High-throughput

0.536

High

235073

DOK2
Docking protein 2

2

5

High-throughput

0.521

High

958022

RIN1
Ras and Rab interactor 1

2

6

High-throughput

0.521

High

958087

ZN473
Zinc finger protein 473

1

0

High-throughput

0.518

High

909441

1433E
14-3-3 protein epsilon

1

3

Small-scale

0.515

High

958051

MYSM1
Deubiquitinase MYSM1

1

3

Small-scale

0.515

High

729203

PDE6B
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta

1

0

High-throughput

0.513

High

869453

ATN1
Atrophin-1

1

2

High-throughput

0.508

High

903886

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

20

High-throughput

0.508

High

958095

PRCC
Proline-rich protein PRCC

1

1

High-throughput

0.508

High

902298

COPZ1
Coatomer subunit zeta-1

1

2

High-throughput

0.489

High

958033

EMC2
ER membrane protein complex subunit 2

1

5

High-throughput

0.489

High

958076

EMC5
ER membrane protein complex subunit 5

1

2

High-throughput

0.489

High

958094

ESR2
Estrogen receptor beta

1

20

High-throughput

0.484

High

209894

PRC1
Protein regulator of cytokinesis 1

1

5

High-throughput

0.481

High

837926

MEOX2
Homeobox protein MOX-2

1

4

High-throughput

0.481

High

958035

PCBP1
Poly(rC)-binding protein 1

1

20

High-throughput

0.481

High

958075

NIN
Ninein

1

3

High-throughput

0.481

High

122664

MEN1
Menin

1

4

High-throughput

0.479

High

125377

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

8

High-throughput

0.479

High

207038

XRCC3
DNA repair protein XRCC3

1

2

High-throughput

0.479

High

232846

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

4

High-throughput

0.479

High

233370

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

298426

UFL1
E3 UFM1-protein ligase 1

1

4

High-throughput

0.479

High

301764

TRI37
E3 ubiquitin-protein ligase TRIM37

1

18

High-throughput

0.479

High

326587

SNAI1
Zinc finger protein SNAI1

1

6

High-throughput

0.479

High

359856

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

6

High-throughput

0.479

High

369406

ESR1
Estrogen receptor

1

20

High-throughput

0.479

High

379294

MYCN
N-myc proto-oncogene protein

1

18

High-throughput

0.479

High

450838

F16P1
Fructose-1,6-bisphosphatase 1

1

2

High-throughput

0.479

High

501975

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

523673

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

569592

CEBPB
CCAAT/enhancer-binding protein beta

1

9

High-throughput

0.479

High

615693

GCSP
Glycine dehydrogenase

1

4

High-throughput

0.479

High

707588

H2B1B
Histone H2B type 1-B

1

4

High-throughput

0.479

High

718756

PHB1
Prohibitin 1

1

4

High-throughput

0.479

High

779241

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

831219

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.479

High

877240

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

20

High-throughput

0.479

High

896034

UBC12
NEDD8-conjugating enzyme Ubc12

1

1

High-throughput

0.479

High

908377

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

913479

RL7A
Large ribosomal subunit protein eL8

1

2

High-throughput

0.479

High

934661

H31
Histone H3.1

1

2

High-throughput

0.479

High

944740

RED1
Double-stranded RNA-specific editase 1

1

19

High-throughput

0.479

High

958004

HSF1
Heat shock factor protein 1

1

3

High-throughput

0.479

High

958010

TP53B
TP53-binding protein 1

1

8

High-throughput

0.479

High

958013

RFA4
Replication protein A 30 kDa subunit

1

7

High-throughput

0.479

High

958023

GRB7
Growth factor receptor-bound protein 7

1

7

Small-scale

0.479

High

958026

MDC1
Mediator of DNA damage checkpoint protein 1

1

11

High-throughput

0.479

High

958027

SMC1A
Structural maintenance of chromosomes protein 1A

1

4

High-throughput

0.479

High

958028

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

3

Small-scale

0.479

High

958034

KIF14
Kinesin-like protein KIF14

1

8

High-throughput

0.479

High

958043

E2F4
Transcription factor E2F4

1

1

High-throughput

0.479

High

958045

IF16
Gamma-interferon-inducible protein 16

1

4

High-throughput

0.479

High

958046

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

3

High-throughput

0.479

High

958047

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

10

High-throughput

0.479

High

958049

RC3H1
Roquin-1

1

11

High-throughput

0.479

High

958054

RNF43
E3 ubiquitin-protein ligase RNF43

1

3

High-throughput

0.479

High

958055

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

958057

NIPBL
Nipped-B-like protein

1

9

High-throughput

0.479

High

958058

WDR82
WD repeat-containing protein 82

1

16

Small-scale

0.479

High

958061

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.479

High

958065

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

6

High-throughput

0.479

High

958066

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

958068

ZCH18
Zinc finger CCCH domain-containing protein 18

1

14

High-throughput

0.479

High

958072

SMC5
Structural maintenance of chromosomes protein 5

1

10

High-throughput

0.479

High

958073

SLX4
Structure-specific endonuclease subunit SLX4

1

5

High-throughput

0.479

High

958078

SIR6
NAD-dependent protein deacylase sirtuin-6

1

8

High-throughput

0.479

High

958084

SP7
Transcription factor Sp7

1

4

High-throughput

0.479

High

958085

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

4

High-throughput

0.479

High

958091

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

6

High-throughput

0.479

High

958092

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

958100

FBXW7
F-box/WD repeat-containing protein 7

1

13

High-throughput

0.479

High

958101

FUBP1
Far upstream element-binding protein 1

1

20

High-throughput

0.479

High

958102

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

15

High-throughput

0.479

High

958104

CDCA5
Sororin

1

1

High-throughput

0.479

High

958111

CIC
Protein capicua homolog

1

13

High-throughput

0.479

High

958112

CDC5L
Cell division cycle 5-like protein

1

4

High-throughput

0.479

High

958114

ANM1
Protein arginine N-methyltransferase 1

1

6

High-throughput

0.479

High

958119

PAR6B
Partitioning defective 6 homolog beta

1

3

High-throughput

0.479

High

958120

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.479

High

958122

WWTR1
WW domain-containing transcription regulator protein 1

1

14

High-throughput

0.479

High

958125

TXNIP
Thioredoxin-interacting protein

1

7

Small-scale

0.479

High

958127

WDR76
WD repeat-containing protein 76

1

12

High-throughput

0.479

High

958133

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

8

High-throughput

0.479

High

958138

RAD18
E3 ubiquitin-protein ligase RAD18

1

2

High-throughput

0.479

High

958140

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

7

High-throughput

0.479

High

958145

AATF
Protein AATF

1

1

High-throughput

0.479

High

958147

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

958151

FBW1B
F-box/WD repeat-containing protein 11

1

13

High-throughput

0.479

High

958153

FZR1
Fizzy-related protein homolog

1

14

High-throughput

0.479

High

958155

SMC3
Structural maintenance of chromosomes protein 3

1

3

High-throughput

0.479

High

958156

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

1

Small-scale

0.479

High

958146

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.460

High

242073

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

958017

ORC1
Origin recognition complex subunit 1

1

0

Small-scale

0.458

High

958030

MTF1
Metal regulatory transcription factor 1

1

0

High-throughput

0.458

High

958032

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

958062

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.458

High

958064

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

958074

STAG2
Cohesin subunit SA-2

1

0

High-throughput

0.458

High

958159

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.458

High

958056

Q6FHY5
MEOX2 protein

1

4

High-throughput

0.457

High

401847

JUN
Transcription factor Jun

1

8

High-throughput

0.445

High

496850

TAU
Microtubule-associated protein tau

1

15

High-throughput

0.445

High

958016

CTBP1
C-terminal-binding protein 1

1

2

High-throughput

0.445

High

958048

NCBP3
Nuclear cap-binding protein subunit 3

1

4

High-throughput

0.445

High

958050

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

10

Small-scale

0.445

High

958113

ZBT18
Zinc finger and BTB domain-containing protein 18

1

6

High-throughput

0.445

High

958129

AGO3
Protein argonaute-3

1

14

High-throughput

0.445

High

958134

AGO4
Protein argonaute-4

1

14

High-throughput

0.445

High

958157

LOXL2
Lysyl oxidase homolog 2

1

2

Small-scale

0.445

High

953064

PR20A
Proline-rich protein 20A

1

1

High-throughput

0.439

High

958040

MARE2
Microtubule-associated protein RP/EB family member 2

1

3

High-throughput

0.439

High

958115

AKAP9
A-kinase anchor protein 9

1

11

High-throughput

0.439

High

958121

NDEL1
Nuclear distribution protein nudE-like 1

1

10

High-throughput

0.439

High

958141

ZF64B
Zinc finger protein 64

1

0

High-throughput

0.438

High

124836

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

3

Small-scale

0.437

High

255685

OBSL1
Obscurin-like protein 1

1

4

High-throughput

0.437

High

958031

CUL7
Cullin-7

1

7

High-throughput

0.437

High

958053

A16L1
Autophagy-related protein 16-1

1

14

High-throughput

0.437

High

958059

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.437

High

958082

RIN3
Ras and Rab interactor 3

1

8

High-throughput

0.437

High

958090

ASB12
Ankyrin repeat and SOCS box protein 12

1

4

High-throughput

0.437

High

958105

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.437

High

958107

SNX27
Sorting nexin-27

1

7

High-throughput

0.437

High

958118

ACE2
Angiotensin-converting enzyme 2

1

3

High-throughput

0.437

High

958124

GAN
Gigaxonin

1

3

High-throughput

0.437

High

958126

PKHA4
Pleckstrin homology domain-containing family A member 4

1

16

High-throughput

0.437

High

958135

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

4

High-throughput

0.437

High

958136

FBX6
F-box only protein 6

1

1

High-throughput

0.437

High

952967

PR20E
Proline-rich protein 20E

1

1

High-throughput

0.417

High

958081

CEP70
Centrosomal protein of 70 kDa

3

0

High-throughput

0.348

High

958079

BEND7
BEN domain-containing protein 7

2

0

High-throughput

0.316

High

958143

TB22B
TBC1 domain family member 22B

1

0

High-throughput

0.299

High

958067

F124A
Protein FAM124A

1

0

High-throughput

0.282

High

958108

AP4AT
AP-4 complex accessory subunit Tepsin

1

0

High-throughput

0.279

Low

952923

PRR5
Proline-rich protein 5

1

0

Small-scale

0.261

Low

958080

SLAI1
SLAIN motif-containing protein 1

1

0

High-throughput

0.251

Low

314304

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

Small-scale

0.249

Low

230612

KATIP
Katanin-interacting protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024