Protein: STK3
Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]

Gene: STK3
Organism: Homo sapiens
Interactions: 185
UniProt ID: Q13188

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0001841 - neural tube formation
GO:0003157 - endocardium development
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1027444

RASF1
Ras association domain-containing protein 1

19

20

Small-scale

0.988

High

841549

RASF2
Ras association domain-containing protein 2

15

13

Small-scale

0.986

High

1027406

RASF5
Ras association domain-containing protein 5

11

13

Small-scale

0.982

High

1023035

STK4
Serine/threonine-protein kinase 4

10

19

Small-scale

0.979

High

325714

LATS1
Serine/threonine-protein kinase LATS1

9

20

Small-scale

0.968

High

1027388

RASF6
Ras association domain-containing protein 6

7

13

Small-scale

0.962

High

1027357

STK3
Serine/threonine-protein kinase 3

6

16

Small-scale

0.951

High

1027396

RASF3
Ras association domain-containing protein 3

6

13

Small-scale

0.946

High

374160

RAF1
RAF proto-oncogene serine/threonine-protein kinase

5

19

Small-scale

0.935

High

1027365

SLMAP
Sarcolemmal membrane-associated protein

4

20

Small-scale

0.911

High

1027429

RASF4
Ras association domain-containing protein 4

7

13

Small-scale

0.868

High

861731

PLK1
Serine/threonine-protein kinase PLK1

3

20

Small-scale

0.866

High

1027443

LATS2
Serine/threonine-protein kinase LATS2

3

19

Small-scale

0.834

High

681822

AKT1
RAC-alpha serine/threonine-protein kinase

2

16

Small-scale

0.834

High

855839

ZN133
Zinc finger protein 133

2

3

High-throughput

0.811

High

1027398

ZN695
Zinc finger protein 695

2

6

High-throughput

0.811

High

1027404

ZN420
Zinc finger protein 420

2

1

High-throughput

0.811

High

1027446

ZIM2
Zinc finger imprinted 2

2

9

High-throughput

0.811

High

1027431

SAV1
Protein salvador homolog 1

18

20

Small-scale

0.766

High

1027403

SNIP1
Smad nuclear-interacting protein 1

2

0

High-throughput

0.742

High

1027447

VAPA
Vesicle-associated membrane protein-associated protein A

5

5

High-throughput

0.725

High

1027390

MARK2
Serine/threonine-protein kinase MARK2

1

7

Small-scale

0.724

High

1027391

MOB1B
MOB kinase activator 1B

5

20

Small-scale

0.723

High

1027437

MOB1A
MOB kinase activator 1A

5

20

Small-scale

0.720

High

807708

MAP1B
Microtubule-associated protein 1B

4

10

High-throughput

0.699

High

1027383

MAP1S
Microtubule-associated protein 1S

4

7

High-throughput

0.699

High

1027457

FBW1A
F-box/WD repeat-containing protein 1A

4

15

Small-scale

0.697

High

282216

SEGN
Secretagogin

1

15

High-throughput

0.691

High

830345

KC1E
Casein kinase I isoform epsilon

1

13

High-throughput

0.691

High

960088

CDK3
Cyclin-dependent kinase 3

1

12

High-throughput

0.691

High

974064

DYST
Dystonin

1

17

High-throughput

0.691

High

1018151

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

16

High-throughput

0.691

High

1027364

RBM39
RNA-binding protein 39

1

2

High-throughput

0.691

High

1027376

ZN718
Zinc finger protein 718

1

6

High-throughput

0.691

High

1027395

ZN554
Zinc finger protein 554

1

8

High-throughput

0.691

High

1027414

AURKB
Aurora kinase B

1

14

High-throughput

0.691

High

1027423

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

3

14

Small-scale

0.676

High

1023648

TRAF1
TNF receptor-associated factor 1

3

12

High-throughput

0.675

High

1027459

PHOCN
MOB-like protein phocein

3

20

Small-scale

0.660

High

1027451

FBW1B
F-box/WD repeat-containing protein 11

3

15

High-throughput

0.656

High

414899

CDK1
Cyclin-dependent kinase 1

1

9

Small-scale

0.647

High

1027381

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

14

Small-scale

0.647

High

471582

TFPT
TCF3 fusion partner

3

0

High-throughput

0.646

High

306153

GBRAP
Gamma-aminobutyric acid receptor-associated protein

2

14

Small-scale

0.636

High

1027422

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

2

14

Small-scale

0.636

High

310619

VAPB
Vesicle-associated membrane protein-associated protein B/C

2

5

High-throughput

0.628

High

1027358

SKP2
S-phase kinase-associated protein 2

2

5

High-throughput

0.628

High

1027402

KIF2B
Kinesin-like protein KIF2B

2

10

High-throughput

0.628

High

1027385

EMB
Embigin

1

7

High-throughput

0.618

High

275738

ZN189
Zinc finger protein 189

1

4

High-throughput

0.618

High

542874

BRAF
Serine/threonine-protein kinase B-raf

1

14

Small-scale

0.618

High

1027366

KIF14
Kinesin-like protein KIF14

1

16

High-throughput

0.618

High

1027370

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

9

High-throughput

0.618

High

1027387

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.618

High

1027432

Q9H4D1
Protein kinase

1

8

High-throughput

0.618

High

1027433

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.618

High

1027449

ANFY1
Rabankyrin-5

1

8

High-throughput

0.618

High

1027427

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

2

14

Small-scale

0.613

High

215226

STRN
Striatin

2

20

High-throughput

0.611

High

683316

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.611

High

981974

1433F
14-3-3 protein eta

2

20

High-throughput

0.611

High

1022814

STRN3
Striatin-3

2

20

High-throughput

0.611

High

1027382

STRP1
Striatin-interacting protein 1

2

12

High-throughput

0.611

High

1027442

STRN4
Striatin-4

2

20

High-throughput

0.611

High

577462

PACA
Pituitary adenylate cyclase-activating polypeptide

3

1

High-throughput

0.609

High

1027394

MOB3B
MOB kinase activator 3B

2

20

High-throughput

0.606

High

1027436

PHAX
Phosphorylated adapter RNA export protein

2

0

High-throughput

0.598

High

1027438

PKHF2
Pleckstrin homology domain-containing family F member 2

1

1

High-throughput

0.594

High

1027369

PTN14
Tyrosine-protein phosphatase non-receptor type 14

2

8

Small-scale

0.584

High

1027412

FBXW7
F-box/WD repeat-containing protein 7

2

14

Small-scale

0.584

High

1027363

KEAP1
Kelch-like ECH-associated protein 1

1

5

Small-scale

0.578

High

883501

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

8

High-throughput

0.575

High

1027359

SQSTM
Sequestosome-1

1

4

High-throughput

0.575

High

1027360

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

Small-scale

0.561

High

1027397

ZDH17
Palmitoyltransferase ZDHHC17

1

12

High-throughput

0.553

High

1027413

CNKR1
Connector enhancer of kinase suppressor of ras 1

1

20

Small-scale

0.553

High

1027418

DCE1
Glutamate decarboxylase 1

1

0

High-throughput

0.549

High

1027420

CPNE1
Copine-1

1

1

High-throughput

0.541

High

117684

MYO1C
Unconventional myosin-Ic

1

15

High-throughput

0.536

High

203125

P52K
52 kDa repressor of the inhibitor of the protein kinase

1

3

High-throughput

0.536

High

391387

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

4

High-throughput

0.536

High

444723

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

4

High-throughput

0.536

High

450648

PAEP
Glycodelin

1

2

High-throughput

0.536

High

596215

NEBU
Nebulin

1

20

High-throughput

0.536

High

904517

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

921548

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

6

High-throughput

0.536

High

926677

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

4

High-throughput

0.536

High

943824

RAE1L
mRNA export factor RAE1

1

4

High-throughput

0.536

High

963311

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

12

High-throughput

0.536

High

1024007

ACACA
Acetyl-CoA carboxylase 1

1

10

High-throughput

0.536

High

1027371

AINX
Alpha-internexin

1

7

High-throughput

0.536

High

1027373

DREB
Drebrin

1

14

High-throughput

0.536

High

1027377

GLYR1
Cytokine-like nuclear factor N-PAC

1

4

High-throughput

0.536

High

1027386

CC174
Coiled-coil domain-containing protein 174

1

1

High-throughput

0.536

High

1027399

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

1027419

KIF2C
Kinesin-like protein KIF2C

1

17

High-throughput

0.536

High

1027426

IQCN
IQ domain-containing protein N

1

1

High-throughput

0.536

High

1027428

TSYL1
Testis-specific Y-encoded-like protein 1

1

1

High-throughput

0.536

High

1027430

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

14

High-throughput

0.536

High

1027435

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.536

High

1027439

CYBP
Calcyclin-binding protein

1

2

High-throughput

0.536

High

1027440

CAN10
Calpain-10

1

2

High-throughput

0.536

High

1027454

ABT1
Activator of basal transcription 1

1

2

High-throughput

0.536

High

1027456

CLC11
C-type lectin domain family 11 member A

1

1

High-throughput

0.536

High

891124

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

14

High-throughput

0.527

High

777179

PEX19
Peroxisomal biogenesis factor 19

1

0

High-throughput

0.518

High

1027378

Q53SE7
Germ cell-less homolog 1

1

7

High-throughput

0.515

High

883411

CF298
Cilia- and flagella-associated protein 298

1

0

High-throughput

0.513

High

1027367

TAF13
Transcription initiation factor TFIID subunit 13

1

0

High-throughput

0.513

High

1027393

CENPV
Centromere protein V

1

0

High-throughput

0.513

High

1027421

CENPO
Centromere protein O

1

0

High-throughput

0.513

High

1027441

RM40
Large ribosomal subunit protein mL40

1

0

High-throughput

0.513

High

1027461

ATG4B
Cysteine protease ATG4B

1

0

High-throughput

0.513

High

690143

GBP2
Guanylate-binding protein 2

1

1

High-throughput

0.508

High

1027410

FUBP2
Far upstream element-binding protein 2

1

5

High-throughput

0.508

High

174844

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

7

High-throughput

0.501

High

362081

MBP
Myelin basic protein

1

2

Small-scale

0.501

High

583970

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

1

High-throughput

0.489

High

1027434

SLIK6
SLIT and NTRK-like protein 6

1

2

High-throughput

0.489

High

1027460

NOP16
Nucleolar protein 16

1

1

High-throughput

0.489

High

814435

SYQ
Glutamine--tRNA ligase

1

0

High-throughput

0.486

High

901352

CH10
10 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.481

High

987719

ST2A1
Sulfotransferase 2A1

1

1

High-throughput

0.481

High

1027400

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

15

High-throughput

0.481

High

1027415

GMCL1
Germ cell-less protein-like 1

1

7

High-throughput

0.481

High

1027361

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

0

Small-scale

0.480

High

162694

XPO1
Exportin-1

1

9

High-throughput

0.479

High

166372

KIF3B
Kinesin-like protein KIF3B

1

7

High-throughput

0.479

High

203675

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

2

High-throughput

0.479

High

270623

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

9

Small-scale

0.479

High

294788

RECQ4
ATP-dependent DNA helicase Q4

1

6

High-throughput

0.479

High

299888

ERLN2
Erlin-2

1

2

High-throughput

0.479

High

318959

CEP43
Centrosomal protein 43

1

2

High-throughput

0.479

High

322560

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

5

High-throughput

0.479

High

502912

MYH3
Myosin-3

1

16

High-throughput

0.479

High

522546

MYH1
Myosin-1

1

16

High-throughput

0.479

High

522610

MYH7
Myosin-7

1

16

High-throughput

0.479

High

528371

MYH6
Myosin-6

1

16

High-throughput

0.479

High

528409

MYH8
Myosin-8

1

16

High-throughput

0.479

High

611430

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

11

Small-scale

0.479

High

646859

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

736431

RL4
Large ribosomal subunit protein uL4

1

4

High-throughput

0.479

High

801509

KPB2
Phosphorylase b kinase regulatory subunit alpha, liver isoform

1

4

High-throughput

0.479

High

874886

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

882277

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

14

High-throughput

0.479

High

909512

1433E
14-3-3 protein epsilon

1

8

High-throughput

0.479

High

926579

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

5

High-throughput

0.479

High

989278

PRDX1
Peroxiredoxin-1

1

4

High-throughput

0.479

High

1027362

CUL3
Cullin-3

1

3

High-throughput

0.479

High

1027375

CL16A
Protein CLEC16A

1

4

High-throughput

0.479

High

1027389

CE128
Centrosomal protein of 128 kDa

1

20

High-throughput

0.479

High

1027392

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

6

High-throughput

0.479

High

1027405

RN128
E3 ubiquitin-protein ligase RNF128

1

1

Small-scale

0.479

High

1027408

RIN2
Ras and Rab interactor 2

1

10

High-throughput

0.479

High

1027409

GOGA1
Golgin subfamily A member 1

1

17

High-throughput

0.479

High

1027411

KPBB
Phosphorylase b kinase regulatory subunit beta

1

4

High-throughput

0.479

High

1027416

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

19

Small-scale

0.479

High

1027445

FGOP2
FGFR1 oncogene partner 2

1

14

High-throughput

0.479

High

1027448

CT2NL
CTTNBP2 N-terminal-like protein

1

20

High-throughput

0.479

High

1027452

MYH2
Myosin-2

1

16

High-throughput

0.479

High

1027453

MYH13
Myosin-13

1

16

High-throughput

0.479

High

1027455

MTMR7
Myotubularin-related protein 7

1

1

High-throughput

0.479

High

1027458

MYH15
Myosin-15

1

16

High-throughput

0.479

High

1027407

JPH3
Junctophilin-3

1

3

High-throughput

0.470

High

958807

EM55
55 kDa erythrocyte membrane protein

1

7

High-throughput

0.464

High

216057

NRDC
Nardilysin

1

0

Small-scale

0.458

High

884634

CORO7
Coronin-7

1

0

Small-scale

0.458

High

1027374

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1027425

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

529063

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.445

High

1027380

GNAS1
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

1

5

High-throughput

0.445

High

1027424

WWTR1
WW domain-containing transcription regulator protein 1

1

20

Small-scale

0.445

High

1027379

FREM1
FRAS1-related extracellular matrix protein 1

1

4

High-throughput

0.437

High

1027384

RNF43
E3 ubiquitin-protein ligase RNF43

1

2

High-throughput

0.437

High

1027450

BIN2
Bridging integrator 2

1

3

Small-scale

0.437

High

353772

IGHG2
Immunoglobulin heavy constant gamma 2

1

10

High-throughput

0.407

High

353932

IGHM
Immunoglobulin heavy constant mu

1

8

High-throughput

0.407

High

1027401

FAM9B
Protein FAM9B

1

0

High-throughput

0.299

High

586100

A1AG2
Alpha-1-acid glycoprotein 2

1

0

High-throughput

0.282

High

550464

ARSB
Arylsulfatase B

1

0

High-throughput

0.279

Low

1027368

TAF1C
TATA box-binding protein-associated factor RNA polymerase I subunit C

1

0

High-throughput

0.279

Low

1027417

RUN3B
RUN domain-containing protein 3B

1

0

High-throughput

0.279

Low

326922

DDAH2
Putative hydrolase DDAH2

1

0

High-throughput

0.265

Low

1027372

TAZ
Tafazzin

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024