Protein: MSPD2
Motile sperm domain-containing protein 2

Gene: MSPD2, MOSPD2
Organism: Homo sapiens
Interactions: 215
UniProt ID: Q8NHP6

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0006935 - chemotaxis
GO:0012505 - endomembrane system

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1340250

VAPA
Vesicle-associated membrane protein-associated protein A

2

3

High-throughput

0.811

High

212452

SPIT2
Kunitz-type protease inhibitor 2

3

3

High-throughput

0.667

High

1192262

ZACN
Ligand-gated cation channel ZACN

3

2

High-throughput

0.667

High

1294795

STX12
Syntaxin-12

3

9

High-throughput

0.667

High

869504

TNFL6
Tumor necrosis factor ligand superfamily member 6

4

0

High-throughput

0.661

High

1165222

F187B
Protein FAM187B

4

0

High-throughput

0.661

High

1133218

STAR3
StAR-related lipid transfer protein 3

2

6

Small-scale

0.649

High

828412

PEX19
Peroxisomal biogenesis factor 19

3

0

High-throughput

0.638

High

1340212

TM171
Transmembrane protein 171

3

0

High-throughput

0.638

High

1340237

OSBL1
Oxysterol-binding protein-related protein 1

2

13

Small-scale

0.634

High

1336019

CTL5
Choline transporter-like protein 5

3

0

High-throughput

0.634

High

669034

FPR2
N-formyl peptide receptor 2

2

3

High-throughput

0.628

High

855357

5HT3A
5-hydroxytryptamine receptor 3A

2

1

High-throughput

0.628

High

893559

GBG4

2

3

High-throughput

0.628

High

1212750

ZFY27
Protrudin

2

1

High-throughput

0.628

High

1316328

AGRG5
Adhesion G-protein coupled receptor G5

2

1

High-throughput

0.628

High

1340217

PTPR2
Receptor-type tyrosine-protein phosphatase N2

2

5

High-throughput

0.628

High

344478

STR3N
STARD3 N-terminal-like protein

2

3

High-throughput

0.621

High

1104298

BT1A1
Butyrophilin subfamily 1 member A1

2

1

High-throughput

0.606

High

1340218

CCD47
PAT complex subunit CCDC47

2

1

High-throughput

0.601

High

1340231

RMD3
Regulator of microtubule dynamics protein 3

2

3

High-throughput

0.594

High

951282

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.584

High

1322558

LSME2
Leucine-rich single-pass membrane protein 2

2

0

High-throughput

0.576

High

1340220

LRC59
Leucine-rich repeat-containing protein 59

2

2

High-throughput

0.571

High

1177846

CL12B
C-type lectin domain family 12 member B

2

2

High-throughput

0.549

High

520701

RRAS
Ras-related protein R-Ras

1

2

High-throughput

0.536

High

932586

PTN5
Tyrosine-protein phosphatase non-receptor type 5

1

3

High-throughput

0.536

High

948074

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

1

3

High-throughput

0.536

High

956945

CXCR4
C-X-C chemokine receptor type 4

1

2

High-throughput

0.536

High

1340239

ACH10
Neuronal acetylcholine receptor subunit alpha-10

1

1

High-throughput

0.536

High

1340253

GBG12

1

3

High-throughput

0.536

High

376625

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

0

High-throughput

0.513

High

469144

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.513

High

1007881

X3CL1
Fractalkine

1

0

High-throughput

0.513

High

1211814

DCST1
E3 ubiquitin-protein ligase DCST1

1

0

High-throughput

0.513

High

1259196

SMIM5
Small integral membrane protein 5

1

0

High-throughput

0.513

High

1340020

O13J1
Olfactory receptor 13J1

1

0

High-throughput

0.513

High

48709

ESYT2
Extended synaptotagmin-2

1

2

High-throughput

0.479

High

126709

RHOD
Rho-related GTP-binding protein RhoD

1

16

High-throughput

0.479

High

174004

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

2

High-throughput

0.479

High

188945

TMPS2
Transmembrane protease serine 2

1

3

High-throughput

0.479

High

218505

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

417606

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.479

High

418287

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

464013

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

12

High-throughput

0.479

High

466367

RHOC
Rho-related GTP-binding protein RhoC

1

13

High-throughput

0.479

High

562246

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

High-throughput

0.479

High

581179

RAC2
Ras-related C3 botulinum toxin substrate 2

1

13

High-throughput

0.479

High

611240

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

5

High-throughput

0.479

High

643380

OSBP1
Oxysterol-binding protein 1

1

16

High-throughput

0.479

High

698918

CALX
Calnexin

1

2

High-throughput

0.479

High

847612

SSRA
Translocon-associated protein subunit alpha

1

1

High-throughput

0.479

High

894915

EMD
Emerin

1

1

High-throughput

0.479

High

901409

RAB7A
Ras-related protein Rab-7a

1

4

High-throughput

0.479

High

904017

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.479

High

952967

ACTB
Actin, cytoplasmic 1

1

1

High-throughput

0.479

High

953572

RAC3
Ras-related C3 botulinum toxin substrate 3

1

13

High-throughput

0.479

High

955391

CDC42
Cell division control protein 42 homolog

1

14

High-throughput

0.479

High

962289

RHOA
Transforming protein RhoA

1

15

High-throughput

0.479

High

1015614

RHOG
Rho-related GTP-binding protein RhoG

1

13

High-throughput

0.479

High

1027097

REEP5
Receptor expression-enhancing protein 5

1

7

High-throughput

0.479

High

1125557

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

2

High-throughput

0.479

High

1211665

MARH8
E3 ubiquitin-protein ligase MARCHF8

1

1

High-throughput

0.479

High

1286837

TM11B
Transmembrane protease serine 11B

1

3

High-throughput

0.479

High

1322902

CXD3
Gap junction delta-3 protein

1

4

High-throughput

0.479

High

1340213

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.479

High

1340222

AP2M1
AP-2 complex subunit mu

1

1

High-throughput

0.479

High

1340226

DNJC1
DnaJ homolog subfamily C member 1

1

4

High-throughput

0.479

High

1340232

SEC62
Translocation protein SEC62

1

1

High-throughput

0.479

High

1340235

DERL1
Derlin-1

1

2

High-throughput

0.479

High

1340238

LNP
Endoplasmic reticulum junction formation protein lunapark

1

2

High-throughput

0.479

High

1340240

DJC25
DnaJ homolog subfamily C member 25

1

4

High-throughput

0.479

High

1340241

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

3

High-throughput

0.479

High

1340243

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.479

High

1340244

TMT1A
Thiol S-methyltransferase TMT1A

1

2

High-throughput

0.479

High

1340245

PXMP2
Peroxisomal membrane protein 2

1

1

High-throughput

0.479

High

1340246

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.479

High

1340247

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.479

High

1340249

ELOV5
Very long chain fatty acid elongase 5

1

2

High-throughput

0.479

High

1340251

TM216
Transmembrane protein 216

1

2

High-throughput

0.479

High

1340252

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

1340254

SEC63
Translocation protein SEC63 homolog

1

2

High-throughput

0.479

High

1340259

CLC4E
C-type lectin domain family 4 member E

1

2

High-throughput

0.479

High

1340260

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.479

High

1340262

CERT
Ceramide transfer protein

1

12

High-throughput

0.479

High

580663

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

693036

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

803

A0A087X0U3
Amino acid transporter

1

3

High-throughput

0.445

High

95787

E5RHW4
Erlin

1

2

High-throughput

0.445

High

96860

E9PDF6
Unconventional myosin-Ib

1

3

High-throughput

0.445

High

114626

H0YLY7
Calcineurin like EF-hand protein 1

1

1

High-throughput

0.445

High

179981

BET1
BET1 homolog

1

3

High-throughput

0.445

High

189986

MOT7
Monocarboxylate transporter 7

1

1

High-throughput

0.445

High

226139

STX6
Syntaxin-6

1

3

High-throughput

0.445

High

250721

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

1

High-throughput

0.445

High

424969

ADT2
ADP/ATP translocase 2

1

1

High-throughput

0.445

High

511010

PRS56
Serine protease 56

1

2

High-throughput

0.445

High

607617

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

4

High-throughput

0.445

High

683289

TNR5
Tumor necrosis factor receptor superfamily member 5

1

1

High-throughput

0.445

High

837733

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

2

High-throughput

0.445

High

844838

EAA1
Excitatory amino acid transporter 1

1

3

High-throughput

0.445

High

912970

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

1

High-throughput

0.445

High

926506

SYRC
Arginine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.445

High

934881

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.445

High

953944

IF4A1
Eukaryotic initiation factor 4A-I

1

3

High-throughput

0.445

High

956758

RAB10
Ras-related protein Rab-10

1

1

High-throughput

0.445

High

1059900

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

1

High-throughput

0.445

High

1098066

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.445

High

1117967

PKP1
Plakophilin-1

1

1

High-throughput

0.445

High

1139350

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

2

High-throughput

0.445

High

1139647

SYK
Lysine--tRNA ligase

1

3

High-throughput

0.445

High

1180293

ATG2A
Autophagy-related protein 2 homolog A

1

2

Small-scale

0.445

High

1277758

MYH14
Myosin-14

1

2

High-throughput

0.445

High

1340209

BICD2
Protein bicaudal D homolog 2

1

4

High-throughput

0.445

High

1340211

S38A5
Sodium-coupled neutral amino acid transporter 5

1

1

High-throughput

0.445

High

1340214

DNJC9
DnaJ homolog subfamily C member 9

1

1

High-throughput

0.445

High

1340215

CTR3
Cationic amino acid transporter 3

1

4

High-throughput

0.445

High

1340216

DDX17
Probable ATP-dependent RNA helicase DDX17

1

1

High-throughput

0.445

High

1340221

FAF2
FAS-associated factor 2

1

4

High-throughput

0.445

High

1340224

FUBP3
Far upstream element-binding protein 3

1

1

High-throughput

0.445

High

1340233

S1PR3
Sphingosine 1-phosphate receptor 3

1

1

High-throughput

0.445

High

1340236

S12A9
Solute carrier family 12 member 9

1

6

High-throughput

0.445

High

1340242

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

1

High-throughput

0.445

High

1340258

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

1

High-throughput

0.445

High

340912

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

3

High-throughput

0.437

High

1238746

TECT3
Tectonic-3

1

2

High-throughput

0.437

High

1254731

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

1340219

S2546
Mitochondrial outer membrane protein SLC25A46

1

2

High-throughput

0.437

High

1340248

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

95959

E7ETK0
40S ribosomal protein S24

1

0

High-throughput

0.426

High

133543

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.426

High

331899

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.426

High

339543

ACSL3
Fatty acid CoA ligase Acsl3

1

0

High-throughput

0.426

High

474839

VIME
Vimentin

1

0

High-throughput

0.426

High

487549

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.426

High

488329

PPBI
Intestinal-type alkaline phosphatase

1

0

High-throughput

0.426

High

538787

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

0

High-throughput

0.426

High

620483

NUCL
Nucleolin

1

0

High-throughput

0.426

High

756278

MCM7
DNA replication licensing factor MCM7

1

0

High-throughput

0.426

High

785309

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.426

High

841835

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.426

High

903623

GALK1
Galactokinase

1

0

High-throughput

0.426

High

961342

RL27
Large ribosomal subunit protein eL27

1

0

High-throughput

0.426

High

975816

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.426

High

977302

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.426

High

981896

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.426

High

1062556

DHX9
ATP-dependent RNA helicase A

1

0

High-throughput

0.426

High

1093388

TRI32
E3 ubiquitin-protein ligase TRIM32

1

0

High-throughput

0.426

High

1131977

MVP
Major vault protein

1

0

High-throughput

0.426

High

1152556

ELAV1
ELAV-like protein 1

1

0

High-throughput

0.426

High

1206049

Q5JR95
Small ribosomal subunit protein eS8

1

0

High-throughput

0.426

High

1236233

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1309132

MISP
Mitotic interactor and substrate of PLK1

1

0

High-throughput

0.426

High

1334671

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.426

High

1340223

S47A1
Multidrug and toxin extrusion protein 1

1

0

High-throughput

0.426

High

1340234

NTPCR
Cancer-related nucleoside-triphosphatase

1

0

High-throughput

0.426

High

1340263

V9GY01
Chromosome 15 open reading frame 23, isoform CRA_d

1

0

High-throughput

0.426

High

1340264

X1WI28
Ribosomal protein L10

1

0

High-throughput

0.426

High

2959

A0A0D9SF54
Spectrin alpha chain, non-erythrocytic 1

1

1

High-throughput

0.407

High

72943

B1AK87
F-actin-capping protein subunit beta

1

1

High-throughput

0.407

High

76452

B4DUR8
T-complex protein 1 subunit gamma

1

2

High-throughput

0.407

High

91810

C9JPX5
STARD3 N-terminal like

1

3

High-throughput

0.407

High

91891

C9JZ20
Prohibitin

1

1

High-throughput

0.407

High

108091

G3V576
Heterogeneous nuclear ribonucleoprotein C

1

1

High-throughput

0.407

High

116456

H7BYN3
Transcription factor A, mitochondrial

1

1

High-throughput

0.407

High

116671

H9KV75
F-actin cross-linking protein

1

1

High-throughput

0.407

High

116741

I3L0K7
TNF receptor associated protein 1

1

4

High-throughput

0.407

High

117064

J3KTA4
Probable ATP-dependent RNA helicase DDX5

1

1

High-throughput

0.407

High

117815

M0R0F0
Small ribosomal subunit protein uS7

1

1

High-throughput

0.407

High

385997

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

4

High-throughput

0.407

High

589210

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.407

High

599830

YBOX3
Y-box-binding protein 3

1

1

High-throughput

0.407

High

651840

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

2

High-throughput

0.407

High

695993

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.407

High

768692

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.407

High

837408

LAP2A
Lamina-associated polypeptide 2, isoform alpha

1

2

High-throughput

0.407

High

899487

TCPD
T-complex protein 1 subunit delta

1

1

High-throughput

0.407

High

1100909

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

High-throughput

0.407

High

1108622

TBB3
Tubulin beta-3 chain

1

1

High-throughput

0.407

High

1118528

TBB2A
Tubulin beta-2A chain

1

1

High-throughput

0.407

High

1150766

SF01
Splicing factor 1

1

1

High-throughput

0.407

High

1340228

BT2A3
Putative butyrophilin subfamily 2 member A3

1

1

High-throughput

0.407

High

1340230

SPAG5
Sperm-associated antigen 5

1

4

High-throughput

0.407

High

1340255

GPN3
GPN-loop GTPase 3

1

1

High-throughput

0.407

High

1340256

PUF60
Poly(U)-binding-splicing factor PUF60

1

1

High-throughput

0.407

High

1340261

PLAK2
PALM2-AKAP2 fusion protein

2

0

High-throughput

0.288

High

49804

CLRN2
Clarin-2

1

0

High-throughput

0.279

Low

1340229

CANB2
Calcineurin subunit B type 2

1

0

High-throughput

0.279

Low

1293080

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1340257

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

719

A0A087WWY3
Filamin A

1

0

High-throughput

0.232

Low

732

A0A087WXM6
Large ribosomal subunit protein uL22

1

0

High-throughput

0.232

Low

3025

A0A0G2JRY5
TATA-box binding protein associated factor 4

1

0

High-throughput

0.232

Low

104026

F5GY55
DNA damage-binding protein 1

1

0

High-throughput

0.232

Low

107431

F8WAE5
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.232

Low

107482

F8WJN3
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.232

Low

109572

G5E9W7
Mitochondrial ribosomal protein S22

1

0

High-throughput

0.232

Low

114522

H0YEN5
Small ribosomal subunit protein uS5

1

0

High-throughput

0.232

Low

116474

H7BYZ9
Mitochondrial amidoxime reducing component 1

1

0

High-throughput

0.232

Low

117103

J3QQQ9
KOW domain-containing protein

1

0

High-throughput

0.232

Low

117118

J3QR09
Ribosomal protein L19

1

0

High-throughput

0.232

Low

449758

H2B1J
Histone H2B type 1-J

1

0

High-throughput

0.232

Low

627684

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.232

Low

635463

CO5A1

1

0

High-throughput

0.232

Low

829470

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

High-throughput

0.232

Low

892050

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.232

Low

978617

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.232

Low

1048602

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.232

Low

1149596

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.232

Low

1149853

TAF7
Transcription initiation factor TFIID subunit 7

1

0

High-throughput

0.232

Low

1241150

LTMD1
LETM1 domain-containing protein 1

1

0

High-throughput

0.232

Low

1333410

S43A3
Equilibrative nucleobase transporter 1

1

0

High-throughput

0.232

Low

1340210

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.232

Low

1340225

HPDL
4-hydroxyphenylpyruvate dioxygenase-like protein

1

0

High-throughput

0.232

Low

1340227

H2A1H
Histone H2A type 1-H

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025