Protein: MPRIP
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)

Gene: MPRIP
Organism: Homo sapiens
Interactions: 216
UniProt ID: Q6WCQ1

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0015629 - actin cytoskeleton
GO:0045296 - cadherin binding
GO:0051015 - actin filament binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1167445

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

4

16

High-throughput

0.903

High

1167432

ANLN
Anillin

4

12

High-throughput

0.895

High

861804

PLK1
Serine/threonine-protein kinase PLK1

3

5

High-throughput

0.871

High

900607

RHOA
Transforming protein RhoA

3

20

Small-scale

0.858

High

1167415

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

2

13

High-throughput

0.811

High

1167446

FBW1A
F-box/WD repeat-containing protein 1A

2

17

High-throughput

0.811

High

647021

1433T
14-3-3 protein theta

8

20

High-throughput

0.750

High

167092

ARHGB
Rho guanine nucleotide exchange factor 11

2

20

High-throughput

0.737

High

683467

1433B
14-3-3 protein beta/alpha

6

20

High-throughput

0.732

High

904740

1433G
14-3-3 protein gamma

6

20

High-throughput

0.732

High

927189

1433Z
14-3-3 protein zeta/delta

5

20

High-throughput

0.712

High

1167412

WDR83
WD repeat domain-containing protein 83

2

18

High-throughput

0.705

High

625495

CDK2
Cyclin-dependent kinase 2

1

14

High-throughput

0.691

High

1052234

SRC8
Src substrate cortactin

1

20

High-throughput

0.691

High

1167423

TARA
TRIO and F-actin-binding protein

1

20

High-throughput

0.691

High

1167441

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

13

High-throughput

0.691

High

982169

1433F
14-3-3 protein eta

4

20

High-throughput

0.691

High

573000

PRS6A
26S proteasome regulatory subunit 6A

3

8

High-throughput

0.667

High

1167372

MPRIP
Myosin phosphatase Rho-interacting protein

1

16

Small-scale

0.665

High

1147606

FTM
Protein fantom

3

20

High-throughput

0.657

High

369860

ESR1
Estrogen receptor

3

20

Small-scale

0.633

High

310686

VAPB
Vesicle-associated membrane protein-associated protein B/C

2

6

High-throughput

0.628

High

1167437

VAPA
Vesicle-associated membrane protein-associated protein A

2

6

High-throughput

0.628

High

1167422

RGAP1
Rac GTPase-activating protein 1

1

11

High-throughput

0.621

High

890712

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

2

5

Small-scale

0.619

High

229958

NUAK1
NUAK family SNF1-like kinase 1

1

9

High-throughput

0.618

High

331308

CHK2
Serine/threonine-protein kinase Chk2

1

12

High-throughput

0.618

High

120502

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

129018

PLK4
Serine/threonine-protein kinase PLK4

1

17

Small-scale

0.618

High

148966

CTRO
Citron Rho-interacting kinase

1

18

High-throughput

0.618

High

338585

EGFR
Epidermal growth factor receptor

1

19

High-throughput

0.618

High

374420

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

15

High-throughput

0.618

High

411772

LCK
Tyrosine-protein kinase Lck

1

13

High-throughput

0.618

High

665271

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

822063

KC1A
Casein kinase I isoform alpha

1

8

High-throughput

0.618

High

901188

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

915771

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

1066291

KIF14
Kinesin-like protein KIF14

1

17

High-throughput

0.618

High

1077849

MYLK
Myosin light chain kinase, smooth muscle

1

12

High-throughput

0.618

High

1083861

NTRK2
BDNF/NT-3 growth factors receptor

1

20

High-throughput

0.618

High

1130230

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

12

Small-scale

0.618

High

1146532

A16L1
Autophagy-related protein 16-1

1

20

High-throughput

0.618

High

1167373

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

20

High-throughput

0.618

High

1167375

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1167395

FBXW7
F-box/WD repeat-containing protein 7

1

17

High-throughput

0.618

High

1167408

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

4

Small-scale

0.618

High

1167410

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

10

High-throughput

0.618

High

1167411

MEP50
Methylosome protein WDR77

1

20

High-throughput

0.618

High

1167414

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

12

High-throughput

0.618

High

1167428

ECT2
Protein ECT2

1

20

High-throughput

0.618

High

1167429

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

1167447

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

1

5

High-throughput

0.618

High

909703

1433E
14-3-3 protein epsilon

2

6

High-throughput

0.611

High

1167378

NAA40
N-alpha-acetyltransferase 40

2

4

High-throughput

0.611

High

1167384

ZFP41
Zinc finger protein 41 homolog

3

2

High-throughput

0.609

High

1167399

SGF29
SAGA-associated factor 29

3

1

High-throughput

0.609

High

529304

CFTR
Cystic fibrosis transmembrane conductance regulator

2

11

High-throughput

0.601

High

684139

1433S
14-3-3 protein sigma

2

20

High-throughput

0.601

High

547104

EZRI
Ezrin

2

20

High-throughput

0.584

High

779625

CCNF
Cyclin-F

2

7

High-throughput

0.584

High

808714

YAP1
Transcriptional coactivator YAP1

2

20

High-throughput

0.584

High

1167448

SERC
Phosphoserine aminotransferase

2

0

High-throughput

0.576

High

882374

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

20

High-throughput

0.575

High

924651

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.575

High

1153259

PKHA7
Pleckstrin homology domain-containing family A member 7

1

19

High-throughput

0.575

High

1167401

JPH4
Junctophilin-4

2

4

High-throughput

0.574

High

161391

MYPT1
Protein phosphatase 1 regulatory subunit 12A

2

19

Small-scale

0.571

High

1068762

PCM1
Pericentriolar material 1 protein

2

3

High-throughput

0.571

High

1138019

SYDE2
Rho GTPase-activating protein SYDE2

2

16

High-throughput

0.571

High

1167417

PP12C
Protein phosphatase 1 regulatory subunit 12C

2

20

Small-scale

0.566

High

1167426

FNDC4
Fibronectin type III domain-containing protein 4

2

13

High-throughput

0.558

High

601535

FGFR2
Fibroblast growth factor receptor 2

1

20

High-throughput

0.553

High

666615

LTK
Leukocyte tyrosine kinase receptor

1

20

High-throughput

0.553

High

1043889

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

20

High-throughput

0.553

High

117737

MYO1C
Unconventional myosin-Ic

1

20

High-throughput

0.536

High

261123

SH3L1
Adapter SH3BGRL

1

1

High-throughput

0.536

High

427901

CAN1
Calpain-1 catalytic subunit

1

5

High-throughput

0.536

High

533381

ACPH
Acylamino-acid-releasing enzyme

1

4

High-throughput

0.536

High

598184

FLNA
Filamin-A

1

20

High-throughput

0.536

High

724884

MYH9
Myosin-9

1

19

High-throughput

0.536

High

809343

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

15

High-throughput

0.536

High

813077

CAZA2
F-actin-capping protein subunit alpha-2

1

12

High-throughput

0.536

High

813557

CAPZB
F-actin-capping protein subunit beta

1

4

High-throughput

0.536

High

827231

ARRB1
Beta-arrestin-1

1

4

High-throughput

0.536

High

906507

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

20

High-throughput

0.536

High

921311

RBX1
E3 ubiquitin-protein ligase RBX1

1

3

High-throughput

0.536

High

984612

CALD1
Caldesmon

1

20

High-throughput

0.536

High

1084979

DREB
Drebrin

1

9

High-throughput

0.536

High

1085783

IF16
Gamma-interferon-inducible protein 16

1

3

High-throughput

0.536

High

1165199

LRSM1
E3 ubiquitin-protein ligase LRSAM1

1

6

High-throughput

0.536

High

1167380

H2B3B
Histone H2B type 3-B

1

19

High-throughput

0.536

High

1167382

SYNPO
Synaptopodin

1

11

High-throughput

0.536

High

1167392

MY18A
Unconventional myosin-XVIIIa

1

20

High-throughput

0.536

High

1167400

MYO19
Unconventional myosin-XIX

1

19

High-throughput

0.536

High

1167433

PDLI7
PDZ and LIM domain protein 7

1

14

High-throughput

0.536

High

1167436

MTMRA
Myotubularin-related protein 10

1

1

High-throughput

0.536

High

1167439

LIMA1
LIM domain and actin-binding protein 1

1

15

High-throughput

0.536

High

1167444

TPX2
Targeting protein for Xklp2

1

1

High-throughput

0.536

High

347113

MYC
Myc proto-oncogene protein

2

14

High-throughput

0.533

High

651504

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

9

High-throughput

0.533

High

1046079

DX39B
Spliceosome RNA helicase DDX39B

2

16

Small-scale

0.533

High

1167430

CENPJ
Centromere protein J

1

19

High-throughput

0.515

High

1167385

NECA1
N-terminal EF-hand calcium-binding protein 1

1

0

High-throughput

0.513

High

1167406

TRNT1
CCA tRNA nucleotidyltransferase 1, mitochondrial

1

0

High-throughput

0.513

High

173969

ATX7
Ataxin-7

1

4

High-throughput

0.508

High

667698

NOS3
Nitric oxide synthase 3

1

2

High-throughput

0.508

High

1167394

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

12

High-throughput

0.501

High

234534

DSCAM
Cell adhesion molecule DSCAM

1

4

High-throughput

0.494

High

846805

SMCA2
Probable global transcription activator SNF2L2

1

13

High-throughput

0.494

High

1144525

AP1AR
AP-1 complex-associated regulatory protein

1

0

High-throughput

0.493

High

150067

TYB4Y
Thymosin beta-4, Y-chromosomal

1

1

High-throughput

0.489

High

260571

TP4A3
Protein tyrosine phosphatase type IVA 3

1

9

High-throughput

0.489

High

296207

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

1

3

High-throughput

0.489

High

330390

CX001
Putative transmembrane protein CXorf1

1

2

High-throughput

0.489

High

373030

VTNC
Vitronectin

1

3

High-throughput

0.489

High

563625

ZNF24
Zinc finger protein 24

1

4

High-throughput

0.489

High

945638

CXCL6
C-X-C motif chemokine 6

1

2

High-throughput

0.489

High

1022717

MALL
MAL-like protein

1

2

High-throughput

0.489

High

1023598

GAGE5
G antigen 5

1

3

High-throughput

0.489

High

1078998

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

4

High-throughput

0.489

High

1167389

HASP
Serine/threonine-protein kinase haspin

1

2

High-throughput

0.489

High

1167391

JPH3
Junctophilin-3

1

4

High-throughput

0.489

High

1167398

ERLEC
Endoplasmic reticulum lectin 1

1

2

High-throughput

0.489

High

1167443

ANR50
Ankyrin repeat domain-containing protein 50

1

10

High-throughput

0.489

High

1167449

NEMO
NF-kappa-B essential modulator

1

20

High-throughput

0.481

High

155383

NRP1
Neuropilin-1

1

8

High-throughput

0.479

High

322779

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

15

High-throughput

0.479

High

345469

FOS
Protein c-Fos

1

5

High-throughput

0.479

High

398010

ISG15
Ubiquitin-like protein ISG15

1

15

High-throughput

0.479

High

430228

PROF1
Profilin-1

1

4

High-throughput

0.479

High

502244

BIP
Endoplasmic reticulum chaperone BiP

1

17

High-throughput

0.479

High

522017

CADH1
Cadherin-1

1

11

High-throughput

0.479

High

590981

BTF3
Transcription factor BTF3

1

8

High-throughput

0.479

High

615767

GCSP
Glycine dehydrogenase

1

4

High-throughput

0.479

High

637460

PSA1
Proteasome subunit alpha type-1

1

2

High-throughput

0.479

High

648805

DPP4
Dipeptidyl peptidase 4

1

4

High-throughput

0.479

High

657514

TMOD1
Tropomodulin-1

1

7

High-throughput

0.479

High

717171

CTNB1
Catenin beta-1

1

16

High-throughput

0.479

High

719735

RADI
Radixin

1

20

High-throughput

0.479

High

726268

BASI
Basigin

1

9

High-throughput

0.479

High

737880

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

20

High-throughput

0.479

High

850092

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

20

High-throughput

0.479

High

870833

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

6

High-throughput

0.479

High

891851

ACTB
Actin, cytoplasmic 1

1

20

High-throughput

0.479

High

896766

ARP3
Actin-related protein 3

1

20

High-throughput

0.479

High

932216

ACTC
Actin, alpha cardiac muscle 1

1

19

High-throughput

0.479

High

969791

KIF23
Kinesin-like protein KIF23

1

20

High-throughput

0.479

High

1016799

TFCP2
Alpha-globin transcription factor CP2

1

5

High-throughput

0.479

High

1036679

SQSTM
Sequestosome-1

1

7

High-throughput

0.479

High

1063889

TNIP1
TNFAIP3-interacting protein 1

1

19

High-throughput

0.479

High

1071909

PCBP1
Poly(rC)-binding protein 1

1

13

Small-scale

0.479

High

1119432

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

10

High-throughput

0.479

High

1119545

MIDN
Midnolin

1

3

High-throughput

0.479

High

1163715

RICTR
Rapamycin-insensitive companion of mTOR

1

4

High-throughput

0.479

High

1167376

SLN11
Schlafen family member 11

1

5

Small-scale

0.479

High

1167386

TRI58
E3 ubiquitin-protein ligase TRIM58

1

7

Small-scale

0.479

High

1167396

CHM4C
Charged multivesicular body protein 4c

1

10

High-throughput

0.479

High

1167419

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

5

High-throughput

0.479

High

1167420

WWTR1
WW domain-containing transcription regulator protein 1

1

20

High-throughput

0.479

High

1167424

DNJC5
DnaJ homolog subfamily C member 5

1

12

High-throughput

0.479

High

1167425

CHM4B
Charged multivesicular body protein 4b

1

10

High-throughput

0.479

High

1167431

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

6

High-throughput

0.479

High

1167438

HDAC6
Histone deacetylase 6

1

18

High-throughput

0.479

High

1167440

SEPT9
Septin-9

1

3

Small-scale

0.479

High

532557

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

1167434

DISC1
Disrupted in schizophrenia 1 protein

1

5

High-throughput

0.457

High

497204

TAU
Microtubule-associated protein tau

1

17

High-throughput

0.445

High

717949

BMI1
Polycomb complex protein BMI-1

1

11

High-throughput

0.445

High

787258

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

13

High-throughput

0.445

High

965125

ANK2
Ankyrin-2

1

14

High-throughput

0.445

High

1081222

NF2L2
Nuclear factor erythroid 2-related factor 2

1

5

High-throughput

0.445

High

1167402

CEP63
Centrosomal protein of 63 kDa

1

20

High-throughput

0.445

High

1167405

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

15

High-throughput

0.445

High

321410

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

3

High-throughput

0.439

High

1167381

PIAS4
E3 SUMO-protein ligase PIAS4

1

3

High-throughput

0.439

High

1167403

YTDC1
YTH domain-containing protein 1

1

2

High-throughput

0.439

High

233514

NUPR1
Nuclear protein 1

1

4

High-throughput

0.437

High

308809

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.437

High

352647

TNFA
Tumor necrosis factor

1

3

High-throughput

0.437

High

442253

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

14

High-throughput

0.437

High

553003

RFA2
Replication protein A 32 kDa subunit

1

9

High-throughput

0.437

High

649127

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

10

High-throughput

0.437

High

720752

RFA3
Replication protein A 14 kDa subunit

1

10

High-throughput

0.437

High

965721

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.437

High

1159377

FBX42
F-box only protein 42

1

14

High-throughput

0.437

High

1166831

LRC31
Leucine-rich repeat-containing protein 31

1

9

High-throughput

0.437

High

1167374

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1167377

TM11B
Transmembrane protease serine 11B

1

5

High-throughput

0.437

High

1167383

SIR6
NAD-dependent protein deacylase sirtuin-6

1

8

High-throughput

0.437

High

1167387

FBX25
F-box only protein 25

1

9

High-throughput

0.437

High

1167388

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.437

High

1167390

RN138
E3 ubiquitin-protein ligase RNF138

1

15

High-throughput

0.437

High

1167393

ESR2
Estrogen receptor beta

1

20

High-throughput

0.437

High

1167416

ACE2
Angiotensin-converting enzyme 2

1

6

High-throughput

0.437

High

1167421

RNF38
E3 ubiquitin-protein ligase RNF38

1

2

Small-scale

0.437

High

1167435

TMPS4
Transmembrane protease serine 4

1

4

High-throughput

0.437

High

240055

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

9

High-throughput

0.407

High

484149

CALM3
Calmodulin-3

1

2

High-throughput

0.407

High

1032479

CTBP1
C-terminal-binding protein 1

1

5

High-throughput

0.407

High

1091123

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

2

High-throughput

0.407

High

1167404

MIA2
Melanoma inhibitory activity protein 2

1

19

High-throughput

0.407

High

1167407

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

20

High-throughput

0.407

High

1167409

ZBT18
Zinc finger and BTB domain-containing protein 18

1

11

High-throughput

0.407

High

1167418

ZDHC5
Palmitoyltransferase ZDHHC5

1

3

High-throughput

0.407

High

159657

QCR10
Cytochrome b-c1 complex subunit 10

1

0

High-throughput

0.279

Low

456890

FURIN
Furin

1

0

High-throughput

0.279

Low

483483

SAA1
Serum amyloid A-1 protein

1

0

High-throughput

0.279

Low

1167379

SYCE1
Synaptonemal complex central element protein 1

1

0

High-throughput

0.279

Low

1167397

OTUB2
Ubiquitin thioesterase OTUB2

1

0

High-throughput

0.279

Low

1167413

TM147
BOS complex subunit TMEM147

1

0

High-throughput

0.279

Low

1167442

MUCEN
Endomucin

1

0

High-throughput

0.279

Low

123628

PGRC1
Membrane-associated progesterone receptor component 1

1

0

Small-scale

0.249

Low

544992

AMPN
Aminopeptidase N

1

0

High-throughput

0.249

Low

1167427

ARMC7
Armadillo repeat-containing protein 7

1

0

High-throughput

0.249

Low

596573

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024