Protein: TOP2A
DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)

Gene: TOP2A
Organism: Homo sapiens
Interactions: 480
UniProt ID: P11388

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0000712 - resolution of meiotic recombination intermediates
GO:0000775 - chromosome, centromeric region
GO:0000793 - condensed chromosome
GO:0000819 - sister chromatid segregation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

542468

TOP2B
DNA topoisomerase 2-beta

3

16

Small-scale

0.853

High

542559

DHX30
ATP-dependent RNA helicase DHX30

1

3

High-throughput

0.691

High

542667

DDX21
Nucleolar RNA helicase 2

1

1

High-throughput

0.691

High

486897

PARP1
Poly [ADP-ribose] polymerase 1

4

2

Small-scale

0.687

High

542631

RBM4B
RNA-binding protein 4B

3

1

High-throughput

0.667

High

542704

ZN451
E3 SUMO-protein ligase ZNF451

3

1

Small-scale

0.667

High

413080

P53
Cellular tumor antigen p53

3

2

Small-scale

0.664

High

542310

XRCC5
X-ray repair cross-complementing protein 5

3

2

Small-scale

0.657

High

259357

BRD4
Bromodomain-containing protein 4

3

11

High-throughput

0.656

High

371027

MYC
Myc proto-oncogene protein

3

2

High-throughput

0.656

High

542432

H4
Histone H4

3

2

High-throughput

0.656

High

542516

CHD4
Chromodomain-helicase-DNA-binding protein 4

3

7

High-throughput

0.656

High

446592

NPM
Nucleophosmin

3

2

High-throughput

0.650

High

542452

RNF4
E3 ubiquitin-protein ligase RNF4

3

1

Small-scale

0.646

High

542451

H31
Histone H3.1

3

10

Small-scale

0.640

High

542461

H33
Histone H3.3

3

10

Small-scale

0.640

High

542358

RL4
Large ribosomal subunit protein uL4

3

0

High-throughput

0.638

High

542361

BRCA1
Breast cancer type 1 susceptibility protein

2

4

Small-scale

0.634

High

542503

HDAC1
Histone deacetylase 1

2

4

Small-scale

0.631

High

238858

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

0

High-throughput

0.631

High

542448

UBC9
SUMO-conjugating enzyme UBC9

2

2

Small-scale

0.629

High

542577

PIAS4
E3 SUMO-protein ligase PIAS4

2

3

Small-scale

0.629

High

542341

3BHS2
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2

2

1

High-throughput

0.628

High

542342

RL10
Large ribosomal subunit protein uL16

2

1

High-throughput

0.628

High

542695

G3BP2
Ras GTPase-activating protein-binding protein 2

2

3

High-throughput

0.628

High

542351

CTNB1
Catenin beta-1

3

0

Small-scale

0.628

High

542309

XRCC6
X-ray repair cross-complementing protein 6

2

2

High-throughput

0.621

High

542450

CSK21
Casein kinase II subunit alpha

2

4

Small-scale

0.619

High

542399

BLM
RecQ-like DNA helicase BLM

1

1

Small-scale

0.618

High

542478

DHX9
ATP-dependent RNA helicase A

1

3

Small-scale

0.618

High

542637

DDX23
Probable ATP-dependent RNA helicase DDX23

1

1

High-throughput

0.618

High

541794

TOP1
DNA topoisomerase 1

2

1

Small-scale

0.612

High

542454

PRKDC
DNA-dependent protein kinase catalytic subunit

2

2

Small-scale

0.612

High

345303

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

6

High-throughput

0.611

High

542350

MCM5
DNA replication licensing factor MCM5

2

1

High-throughput

0.611

High

542384

CTCF
Transcriptional repressor CTCF

2

1

Small-scale

0.611

High

542439

RL31
Large ribosomal subunit protein eL31

2

1

High-throughput

0.611

High

542629

H2B1L
Histone H2B type 1-L

2

14

High-throughput

0.611

High

542660

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

2

1

High-throughput

0.611

High

542388

TSP3
Thrombospondin-3

3

1

High-throughput

0.609

High

542600

CSN5
COP9 signalosome complex subunit 5

2

3

Small-scale

0.606

High

542473

KPCD
Protein kinase C delta type

1

6

Small-scale

0.603

High

542398

PLK1
Serine/threonine-protein kinase PLK1

2

2

Small-scale

0.602

High

542417

SUMO2
Small ubiquitin-related modifier 2

2

4

High-throughput

0.602

High

542414

RL15
Large ribosomal subunit protein eL15

2

0

High-throughput

0.602

High

542570

F131B
Protein FAM131B

2

0

High-throughput

0.602

High

542320

HMGA1
High mobility group protein HMG-I/HMG-Y

2

1

High-throughput

0.601

High

542395

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

2

11

Small-scale

0.601

High

542605

H2B1H
Histone H2B type 1-H

2

15

High-throughput

0.601

High

542495

ATM
Serine-protein kinase ATM

1

2

Small-scale

0.586

High

542624

CDC5L
Cell division cycle 5-like protein

2

0

Small-scale

0.585

High

429201

JUN
Transcription factor Jun

2

2

Small-scale

0.585

High

180679

TIF1A
Transcription intermediary factor 1-alpha

2

6

Small-scale

0.584

High

256754

H2B1K
Histone H2B type 1-K

2

15

High-throughput

0.584

High

385399

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

5

High-throughput

0.584

High

449669

H2B1J
Histone H2B type 1-J

2

15

High-throughput

0.584

High

542317

RFA2
Replication protein A 32 kDa subunit

2

2

High-throughput

0.584

High

542343

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

2

High-throughput

0.584

High

542353

RFA3
Replication protein A 14 kDa subunit

2

1

High-throughput

0.584

High

542405

H2B1D
Histone H2B type 1-D

2

15

High-throughput

0.584

High

542493

TIF1B
Transcription intermediary factor 1-beta

2

4

Small-scale

0.584

High

542530

EZH2
Histone-lysine N-methyltransferase EZH2

2

2

High-throughput

0.584

High

542541

SETMR
Histone-lysine N-methyltransferase SETMAR

2

2

Small-scale

0.584

High

542606

FBXW7
F-box/WD repeat-containing protein 7

2

5

Small-scale

0.584

High

542666

ANLN
Anillin

2

1

High-throughput

0.584

High

542683

ZRAN1
Ubiquitin thioesterase ZRANB1

2

3

High-throughput

0.584

High

542659

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

4

Small-scale

0.578

High

542304

TOP2A
DNA topoisomerase 2-alpha

1

16

Small-scale

0.575

High

542709

ASB3
Ankyrin repeat and SOCS box protein 3

2

2

High-throughput

0.574

High

542515

PSF1
DNA replication complex GINS protein PSF1

1

1

Small-scale

0.561

High

542574

RN168
E3 ubiquitin-protein ligase RNF168

1

2

Small-scale

0.561

High

542623

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

10

Small-scale

0.561

High

542381

RL29
Large ribosomal subunit protein eL29

2

0

High-throughput

0.559

High

542646

CCDC8
Coiled-coil domain-containing protein 8

2

0

High-throughput

0.559

High

179668

MDM4
Protein Mdm4

1

0

Small-scale

0.537

High

542649

CDT1
DNA replication factor Cdt1

1

0

Small-scale

0.537

High

542346

MK01
Mitogen-activated protein kinase 1

1

2

Small-scale

0.536

High

140723

NOP56
Nucleolar protein 56

1

2

High-throughput

0.536

High

154618

ARI1A
AT-rich interactive domain-containing protein 1A

1

3

Small-scale

0.536

High

187873

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

4

High-throughput

0.536

High

231090

AIRE
Autoimmune regulator

1

10

Small-scale

0.536

High

277537

H2AY
Core histone macro-H2A.1

1

9

High-throughput

0.536

High

316735

MTA2
Metastasis-associated protein MTA2

1

2

High-throughput

0.536

High

348045

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

3

High-throughput

0.536

High

391177

FRIL
Ferritin light chain

1

3

High-throughput

0.536

High

395388

ESR1
Estrogen receptor

1

7

High-throughput

0.536

High

481061

HMGB1
High mobility group protein B1

1

5

High-throughput

0.536

High

501899

H2AZ
Histone H2A.Z

1

9

High-throughput

0.536

High

542308

CADH1
Cadherin-1

1

1

High-throughput

0.536

High

542315

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.536

High

542319

NCK1
SH2/SH3 adapter protein NCK1

1

1

High-throughput

0.536

High

542331

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

1

High-throughput

0.536

High

542334

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.536

High

542336

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.536

High

542339

PSA2
Proteasome subunit alpha type-2

1

1

High-throughput

0.536

High

542347

LTK
Leukocyte tyrosine kinase receptor

1

1

High-throughput

0.536

High

542354

RL22
Large ribosomal subunit protein eL22

1

1

High-throughput

0.536

High

542357

TCF7
Transcription factor 7

1

3

High-throughput

0.536

High

542359

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

4

High-throughput

0.536

High

542367

RL35
Large ribosomal subunit protein uL29

1

1

High-throughput

0.536

High

542370

MAGA9
Melanoma-associated antigen 9

1

1

High-throughput

0.536

High

542371

PRS6B
26S proteasome regulatory subunit 6B

1

3

High-throughput

0.536

High

542387

PSB3
Proteasome subunit beta type-3

1

3

High-throughput

0.536

High

542392

CDK7
Cyclin-dependent kinase 7

1

1

High-throughput

0.536

High

542394

FXR2
RNA-binding protein FXR2

1

3

High-throughput

0.536

High

542402

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

3

High-throughput

0.536

High

542408

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.536

High

542409

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.536

High

542410

PSA6
Proteasome subunit alpha type-6

1

1

High-throughput

0.536

High

542411

SRP54
Signal recognition particle subunit SRP54

1

1

High-throughput

0.536

High

542412

ABCE1
ATP-binding cassette sub-family E member 1

1

2

High-throughput

0.536

High

542416

RL27
Large ribosomal subunit protein eL27

1

1

High-throughput

0.536

High

542419

PRS4
26S proteasome regulatory subunit 4

1

3

High-throughput

0.536

High

542420

PRS8
26S proteasome regulatory subunit 8

1

3

High-throughput

0.536

High

542422

RS15A
Small ribosomal subunit protein uS8

1

1

High-throughput

0.536

High

542423

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.536

High

542427

RS18
Small ribosomal subunit protein uS13

1

1

High-throughput

0.536

High

542429

PRS10
26S proteasome regulatory subunit 10B

1

3

High-throughput

0.536

High

542435

RS24
Small ribosomal subunit protein eS24

1

1

High-throughput

0.536

High

542440

RL10A
Large ribosomal subunit protein uL1

1

2

High-throughput

0.536

High

542441

RL11
Large ribosomal subunit protein uL5

1

2

High-throughput

0.536

High

542442

RL8
Large ribosomal subunit protein uL2

1

2

High-throughput

0.536

High

542447

RACK1
Small ribosomal subunit protein RACK1

1

5

High-throughput

0.536

High

542449

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.536

High

542453

SRPK2
SRSF protein kinase 2

1

5

High-throughput

0.536

High

542457

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

1

High-throughput

0.536

High

542462

CDKL1
Cyclin-dependent kinase-like 1

1

2

High-throughput

0.536

High

542464

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.536

High

542471

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

1

High-throughput

0.536

High

542475

FMR1
Fragile X messenger ribonucleoprotein 1

1

3

High-throughput

0.536

High

542479

SSRP1
FACT complex subunit SSRP1

1

8

High-throughput

0.536

High

542481

RBBP4
Histone-binding protein RBBP4

1

4

High-throughput

0.536

High

542488

ILF3
Interleukin enhancer-binding factor 3

1

7

High-throughput

0.536

High

542494

G3BP1
Ras GTPase-activating protein-binding protein 1

1

3

High-throughput

0.536

High

542497

MTA1
Metastasis-associated protein MTA1

1

2

High-throughput

0.536

High

542502

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

1

High-throughput

0.536

High

542505

KGP1
cGMP-dependent protein kinase 1

1

6

High-throughput

0.536

High

542509

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

1

High-throughput

0.536

High

542511

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

3

High-throughput

0.536

High

542513

CAPR1
Caprin-1

1

4

High-throughput

0.536

High

542517

NUMA1
Nuclear mitotic apparatus protein 1

1

2

High-throughput

0.536

High

542519

CND2
Condensin complex subunit 2

1

2

High-throughput

0.536

High

542524

TEBP
Prostaglandin E synthase 3

1

3

High-throughput

0.536

High

542535

H2A2C
Histone H2A type 2-C

1

7

High-throughput

0.536

High

542536

H2B2E
Histone H2B type 2-E

1

15

High-throughput

0.536

High

542537

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

1

High-throughput

0.536

High

542542

DJC21
DnaJ homolog subfamily C member 21

1

1

High-throughput

0.536

High

542550

MED27
Mediator of RNA polymerase II transcription subunit 27

1

1

High-throughput

0.536

High

542553

GGYF2
GRB10-interacting GYF protein 2

1

1

High-throughput

0.536

High

542558

COX15
Heme A synthase COX15

1

1

High-throughput

0.536

High

542563

YTHD3
YTH domain-containing family protein 3

1

3

High-throughput

0.536

High

542565

PB1
Protein polybromo-1

1

14

High-throughput

0.536

High

542567

KTN1
Kinectin

1

3

High-throughput

0.536

High

542571

P66A
Transcriptional repressor p66-alpha

1

1

High-throughput

0.536

High

542572

H2A2B
Histone H2A type 2-B

1

5

High-throughput

0.536

High

542586

NEK9
Serine/threonine-protein kinase Nek9

1

1

High-throughput

0.536

High

542588

GRK7
Rhodopsin kinase GRK7

1

5

High-throughput

0.536

High

542592

P66B
Transcriptional repressor p66-beta

1

1

High-throughput

0.536

High

542597

TFG
Protein TFG

1

2

High-throughput

0.536

High

542603

CUL5
Cullin-5

1

4

High-throughput

0.536

High

542604

H2A1C
Histone H2A type 1-C

1

7

High-throughput

0.536

High

542609

TRI52
E3 ubiquitin-protein ligase TRIM52

1

1

High-throughput

0.536

High

542618

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

2

High-throughput

0.536

High

542621

SRPK1
SRSF protein kinase 1

1

6

High-throughput

0.536

High

542622

IWS1
Protein IWS1 homolog

1

3

High-throughput

0.536

High

542625

RING2
E3 ubiquitin-protein ligase RING2

1

5

High-throughput

0.536

High

542628

H2A1J
Histone H2A type 1-J

1

7

High-throughput

0.536

High

542644

LSG1
Large subunit GTPase 1 homolog

1

1

High-throughput

0.536

High

542648

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

1

High-throughput

0.536

High

542650

FOXP1
Forkhead box protein P1

1

3

High-throughput

0.536

High

542654

PLK3
Serine/threonine-protein kinase PLK3

1

1

High-throughput

0.536

High

542664

DCP1A
mRNA-decapping enzyme 1A

1

1

High-throughput

0.536

High

542677

H2AW
Core histone macro-H2A.2

1

9

High-throughput

0.536

High

542682

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.536

High

542687

BAZ1B
Tyrosine-protein kinase BAZ1B

1

13

High-throughput

0.536

High

542688

FOXD3
Forkhead box protein D3

1

4

High-throughput

0.536

High

542689

KS6A6
Ribosomal protein S6 kinase alpha-6

1

1

High-throughput

0.536

High

542697

SRPK3
SRSF protein kinase 3

1

4

High-throughput

0.536

High

542699

DRG1
Developmentally-regulated GTP-binding protein 1

1

2

High-throughput

0.536

High

542701

KLH20
Kelch-like protein 20

1

2

High-throughput

0.536

High

542708

PRC2C
Protein PRRC2C

1

4

High-throughput

0.536

High

542327

VCAM1
Vascular cell adhesion protein 1

2

1

High-throughput

0.521

High

542397

HMGA2
High mobility group protein HMGI-C

1

2

Small-scale

0.515

High

542534

H31T
Histone H3.1t

1

10

High-throughput

0.515

High

192896

CLOCK
Circadian locomoter output cycles protein kaput

1

0

High-throughput

0.513

High

271403

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.513

High

285573

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.513

High

303396

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.513

High

359584

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.513

High

428046

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.513

High

428276

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.513

High

475248

RS17
Small ribosomal subunit protein eS17

1

0

High-throughput

0.513

High

542305

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.513

High

542306

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.513

High

542312

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

542323

CAN2
Calpain-2 catalytic subunit

1

0

High-throughput

0.513

High

542325

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.513

High

542326

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.513

High

542328

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.513

High

542349

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.513

High

542363

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.513

High

542364

FEN1
Flap endonuclease 1

1

0

High-throughput

0.513

High

542374

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

542375

RL21
Large ribosomal subunit protein eL21

1

0

High-throughput

0.513

High

542376

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.513

High

542377

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

542378

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

542379

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.513

High

542393

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.513

High

542413

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.513

High

542415

MGN
Protein mago nashi homolog

1

0

High-throughput

0.513

High

542418

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.513

High

542421

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.513

High

542426

RS14
Small ribosomal subunit protein uS11

1

0

High-throughput

0.513

High

542428

RS29
Small ribosomal subunit protein uS14

1

0

High-throughput

0.513

High

542430

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.513

High

542434

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.513

High

542436

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.513

High

542438

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.513

High

542446

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.513

High

542458

RL24
Large ribosomal subunit protein eL24

1

0

High-throughput

0.513

High

542460

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

542476

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.513

High

542490

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

1

0

High-throughput

0.513

High

542506

CKAP5
Cytoskeleton-associated protein 5

1

0

High-throughput

0.513

High

542508

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

542532

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.513

High

542545

HP1B3
Heterochromatin protein 1-binding protein 3

1

0

High-throughput

0.513

High

542551

ULK3
Serine/threonine-protein kinase ULK3

1

0

High-throughput

0.513

High

542556

MED25
Mediator of RNA polymerase II transcription subunit 25

1

0

High-throughput

0.513

High

542557

RS27L
Ribosomal protein eS27-like

1

0

High-throughput

0.513

High

542566

LYRIC
Protein LYRIC

1

0

High-throughput

0.513

High

542581

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.513

High

542595

TRIB2
Tribbles homolog 2

1

0

High-throughput

0.513

High

542633

CHOLN
Protein cholesin

1

0

High-throughput

0.513

High

542634

LLPH
Protein LLP homolog

1

0

High-throughput

0.513

High

542635

CENPK
Centromere protein K

1

0

High-throughput

0.513

High

542636

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.513

High

542665

EXOS5
Exosome complex component RRP46

1

0

High-throughput

0.513

High

542684

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.513

High

542691

INTU
Protein inturned

1

0

High-throughput

0.513

High

542698

RUVB2
RuvB-like 2

1

0

High-throughput

0.513

High

542703

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.513

High

542707

ATG4B
Cysteine protease ATG4B

1

0

High-throughput

0.513

High

303029

DFFB
DNA fragmentation factor subunit beta

1

1

Small-scale

0.501

High

424626

KPCG
Protein kinase C gamma type

1

6

Small-scale

0.501

High

436595

KPCB
Protein kinase C beta type

1

6

Small-scale

0.501

High

542321

KPCA
Protein kinase C alpha type

1

5

Small-scale

0.501

High

542507

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

2

Small-scale

0.501

High

542602

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

3

High-throughput

0.501

High

172436

XPO1
Exportin-1

1

1

Small-scale

0.500

High

542690

AGO2
Protein argonaute-2

1

1

Small-scale

0.500

High

542501

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

Small-scale

0.493

High

542662

RESF1
Retroelement silencing factor 1

1

0

High-throughput

0.493

High

542380

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.489

High

542469

LMNB2
Lamin-B2

1

5

High-throughput

0.489

High

542562

UBE3B
Ubiquitin-protein ligase E3B

1

5

High-throughput

0.489

High

542582

NECP1
Adaptin ear-binding coat-associated protein 1

1

1

High-throughput

0.489

High

542368

WASP
Actin nucleation-promoting factor WAS

1

3

Small-scale

0.484

High

125184

LEG9
Galectin-9

1

1

High-throughput

0.479

High

128738

MEN1
Menin

1

1

High-throughput

0.479

High

131695

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

4

High-throughput

0.479

High

137935

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

3

Small-scale

0.479

High

142800

NFIB
Nuclear factor 1 B-type

1

2

High-throughput

0.479

High

156892

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

190801

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

4

High-throughput

0.479

High

222670

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

240594

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

247631

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

248266

HBP1
HMG box-containing protein 1

1

2

High-throughput

0.479

High

271856

OBSL1
Obscurin-like protein 1

1

3

High-throughput

0.479

High

284056

SRS10
Serine/arginine-rich splicing factor 10

1

2

Small-scale

0.479

High

285055

EED
Polycomb protein EED

1

7

High-throughput

0.479

High

302739

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

7

High-throughput

0.479

High

330614

KI20A
Kinesin-like protein KIF20A

1

5

High-throughput

0.479

High

355416

NSD2
Histone-lysine N-methyltransferase NSD2

1

5

Small-scale

0.479

High

418805

H2A1B
Histone H2A type 1-B/E

1

7

High-throughput

0.479

High

425277

ISG15
Ubiquitin-like protein ISG15

1

5

High-throughput

0.479

High

472424

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.479

High

473750

NFIC
Nuclear factor 1 C-type

1

3

High-throughput

0.479

High

536380

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

542322

KCRS
Creatine kinase S-type, mitochondrial

1

1

High-throughput

0.479

High

542324

CEBPB
CCAAT/enhancer-binding protein beta

1

4

High-throughput

0.479

High

542332

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.479

High

542333

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

7

Small-scale

0.479

High

542335

H2B1O
Histone H2B type 1-O

1

15

High-throughput

0.479

High

542337

BRD2
Bromodomain-containing protein 2

1

14

High-throughput

0.479

High

542340

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.479

High

542344

PSB5
Proteasome subunit beta type-5

1

2

Small-scale

0.479

High

542348

PML
Protein PML

1

4

High-throughput

0.479

High

542352

BMI1
Polycomb complex protein BMI-1

1

2

Small-scale

0.479

High

542355

CYLC1
Cylicin-1

1

2

High-throughput

0.479

High

542362

COIL
Coilin

1

1

High-throughput

0.479

High

542366

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

542369

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

7

High-throughput

0.479

High

542372

GATA4
Transcription factor GATA-4

1

2

High-throughput

0.479

High

542382

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

542383

CENPA
Histone H3-like centromeric protein A

1

10

High-throughput

0.479

High

542386

CEBPD
CCAAT/enhancer-binding protein delta

1

6

Small-scale

0.479

High

542389

RBP2
E3 SUMO-protein ligase RanBP2

1

3

Small-scale

0.479

High

542390

GSK3B
Glycogen synthase kinase-3 beta

1

3

Small-scale

0.479

High

542400

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

6

High-throughput

0.479

High

542401

FOXA1
Hepatocyte nuclear factor 3-alpha

1

3

High-throughput

0.479

High

542403

IF6
Eukaryotic translation initiation factor 6

1

1

High-throughput

0.479

High

542404

H2BFS
Histone H2B type F-S

1

15

High-throughput

0.479

High

542425

1433E
14-3-3 protein epsilon

1

2

Small-scale

0.479

High

542431

RS6
Small ribosomal subunit protein eS6

1

1

High-throughput

0.479

High

542433

H2B1C
Histone H2B type 1-C/E/F/G/I

1

15

High-throughput

0.479

High

542443

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

3

High-throughput

0.479

High

542444

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

2

High-throughput

0.479

High

542445

RAC1
Ras-related C3 botulinum toxin substrate 1

1

7

Small-scale

0.479

High

542455

RED1
Double-stranded RNA-specific editase 1

1

6

High-throughput

0.479

High

542456

BASP1
Brain acid soluble protein 1

1

2

High-throughput

0.479

High

542459

RL36A
Large ribosomal subunit protein eL42

1

1

High-throughput

0.479

High

542466

KIF23
Kinesin-like protein KIF23

1

3

High-throughput

0.479

High

542467

RL6
Large ribosomal subunit protein eL6

1

1

High-throughput

0.479

High

542470

ERCC6
DNA excision repair protein ERCC-6

1

14

Small-scale

0.479

High

542472

TLE2
Transducin-like enhancer protein 2

1

6

High-throughput

0.479

High

542474

RING1
E3 ubiquitin-protein ligase RING1

1

5

Small-scale

0.479

High

542477

FOXM1
Forkhead box protein M1

1

3

Small-scale

0.479

High

542483

EP300
Histone acetyltransferase p300

1

12

High-throughput

0.479

High

542485

NFIA
Nuclear factor 1 A-type

1

3

High-throughput

0.479

High

542487

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

7

High-throughput

0.479

High

542489

RFA4
Replication protein A 30 kDa subunit

1

2

High-throughput

0.479

High

542491

CBX3
Chromobox protein homolog 3

1

2

High-throughput

0.479

High

542492

ERCC8
DNA excision repair protein ERCC-8

1

8

High-throughput

0.479

High

542499

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

3

High-throughput

0.479

High

542500

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

542504

CUL2
Cullin-2

1

4

Small-scale

0.479

High

542510

RCN2
Reticulocalbin-2

1

2

High-throughput

0.479

High

542514

RBM39
RNA-binding protein 39

1

2

High-throughput

0.479

High

542518

CUL7
Cullin-7

1

1

High-throughput

0.479

High

542520

TNIP1
TNFAIP3-interacting protein 1

1

4

High-throughput

0.479

High

542521

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

542522

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

542523

BRD3
Bromodomain-containing protein 3

1

16

High-throughput

0.479

High

542525

RBBP5
Retinoblastoma-binding protein 5

1

7

High-throughput

0.479

High

542526

ZMY11
Zinc finger MYND domain-containing protein 11

1

7

Small-scale

0.479

High

542527

PCBP1
Poly(rC)-binding protein 1

1

1

Small-scale

0.479

High

542533

IF16
Gamma-interferon-inducible protein 16

1

3

High-throughput

0.479

High

542539

MIDN
Midnolin

1

1

High-throughput

0.479

High

542540

GLE1
mRNA export factor GLE1

1

2

High-throughput

0.479

High

542544

H2B2F
Histone H2B type 2-F

1

15

High-throughput

0.479

High

542548

IFIX
Pyrin and HIN domain-containing protein 1

1

3

High-throughput

0.479

High

542552

WDR82
WD repeat-containing protein 82

1

11

High-throughput

0.479

High

542554

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

542555

H32
Histone H3.2

1

10

High-throughput

0.479

High

542568

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

542569

ZCH18
Zinc finger CCCH domain-containing protein 18

1

4

High-throughput

0.479

High

542573

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.479

High

542575

KMT2E
Inactive histone-lysine N-methyltransferase 2E

1

4

Small-scale

0.479

High

542576

SPICE
Spindle and centriole-associated protein 1

1

1

High-throughput

0.479

High

542578

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

1

High-throughput

0.479

High

542579

SIR6
NAD-dependent protein deacylase sirtuin-6

1

2

High-throughput

0.479

High

542585

NUP43
Nucleoporin Nup43

1

11

High-throughput

0.479

High

542587

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

542590

DCAF4
DDB1- and CUL4-associated factor 4

1

1

High-throughput

0.479

High

542593

TITIN
Titin

1

5

High-throughput

0.479

High

542594

DDB2
DNA damage-binding protein 2

1

10

High-throughput

0.479

High

542596

TOPB1
DNA topoisomerase 2-binding protein 1

1

5

High-throughput

0.479

High

542598

HDAC2
Histone deacetylase 2

1

4

Small-scale

0.479

High

542599

KAT6A
Histone acetyltransferase KAT6A

1

8

High-throughput

0.479

High

542601

SMRC1
SWI/SNF complex subunit SMARCC1

1

3

Small-scale

0.479

High

542611

DCPS
m7GpppX diphosphatase

1

1

High-throughput

0.479

High

542612

CHM4C
Charged multivesicular body protein 4c

1

2

High-throughput

0.479

High

542613

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

10

High-throughput

0.479

High

542614

MBD6
Methyl-CpG-binding domain protein 6

1

2

High-throughput

0.479

High

542626

NECD
Necdin

1

1

High-throughput

0.479

High

542627

H2B1N
Histone H2B type 1-N

1

15

High-throughput

0.479

High

542630

VRK1
Serine/threonine-protein kinase VRK1

1

2

High-throughput

0.479

High

542632

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

5

High-throughput

0.479

High

542638

FACD2
Fanconi anemia group D2 protein

1

3

High-throughput

0.479

High

542640

YTHD1
YTH domain-containing family protein 1

1

3

High-throughput

0.479

High

542642

WWTR1
WW domain-containing transcription regulator protein 1

1

6

High-throughput

0.479

High

542643

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

2

High-throughput

0.479

High

542651

P63
Tumor protein 63

1

2

Small-scale

0.479

High

542653

CHM4B
Charged multivesicular body protein 4b

1

2

High-throughput

0.479

High

542655

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

12

High-throughput

0.479

High

542656

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

542658

ECT2
Protein ECT2

1

5

High-throughput

0.479

High

542661

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

4

High-throughput

0.479

High

542668

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

2

Small-scale

0.479

High

542670

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.479

High

542671

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

4

High-throughput

0.479

High

542673

NLE1
Notchless protein homolog 1

1

4

High-throughput

0.479

High

542678

MBD5
Methyl-CpG-binding domain protein 5

1

1

High-throughput

0.479

High

542679

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

2

High-throughput

0.479

High

542680

PAK5
Serine/threonine-protein kinase PAK 5

1

1

Small-scale

0.479

High

542681

CLIP2
CAP-Gly domain-containing linker protein 2

1

1

High-throughput

0.479

High

542685

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

2

High-throughput

0.479

High

542686

XPO7
Exportin-7

1

1

High-throughput

0.479

High

542694

MYO6
Unconventional myosin-VI

1

2

High-throughput

0.479

High

542702

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

542705

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

2

Small-scale

0.479

High

542706

LOXL2
Lysyl oxidase homolog 2

1

1

High-throughput

0.479

High

66843

DUXA
Double homeobox protein A

1

0

High-throughput

0.458

High

171829

ZN263
Zinc finger protein 263

1

0

Small-scale

0.458

High

293119

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

365279

PGK1
Phosphoglycerate kinase 1

1

0

High-throughput

0.458

High

442559

RB
Retinoblastoma-associated protein

1

0

Small-scale

0.458

High

445113

S10A6
Protein S100-A6

1

0

High-throughput

0.458

High

446120

PYGL
Glycogen phosphorylase, liver form

1

0

High-throughput

0.458

High

482288

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.458

High

542311

IFM1
Interferon-induced transmembrane protein 1

1

0

High-throughput

0.458

High

542314

HCLS1
Hematopoietic lineage cell-specific protein

1

0

High-throughput

0.458

High

542329

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

542345

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.458

High

542356

VGFR2
Vascular endothelial growth factor receptor 2

1

0

High-throughput

0.458

High

542360

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

542365

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.458

High

542373

NKX21
Homeobox protein Nkx-2.1

1

0

High-throughput

0.458

High

542391

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.458

High

542406

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

542424

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

542463

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

542484

MN1
Transcriptional activator MN1

1

0

Small-scale

0.458

High

542486

MERTK
Tyrosine-protein kinase Mer

1

0

High-throughput

0.458

High

542496

CD5R2
Cyclin-dependent kinase 5 activator 2

1

0

High-throughput

0.458

High

542528

ELOC
Elongin-C

1

0

Small-scale

0.458

High

542529

TERF2
Telomeric repeat-binding factor 2

1

0

Small-scale

0.458

High

542531

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

542561

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

542564

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

542580

ZBT38
Zinc finger and BTB domain-containing protein 38

1

0

Small-scale

0.458

High

542607

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

542610

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

542616

AURKB
Aurora kinase B

1

0

High-throughput

0.458

High

542617

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

542620

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

542663

SHCAF
SIN3-HDAC complex-associated factor

1

0

Small-scale

0.458

High

542674

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

542675

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

58789

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

1

High-throughput

0.445

High

116374

H3BUK8
Large ribosomal subunit protein eL13

1

1

High-throughput

0.445

High

117826

M0R1M6
Ubiquitin-ribosomal protein eL40 fusion protein

1

3

High-throughput

0.445

High

542307

KCRU
Creatine kinase U-type, mitochondrial

1

1

High-throughput

0.445

High

542316

ITF2
Transcription factor 4

1

1

Small-scale

0.445

High

542318

H2AX
Histone H2AX

1

8

Small-scale

0.445

High

542396

NCBP2
Nuclear cap-binding protein subunit 2

1

1

High-throughput

0.445

High

542437

RS30
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein

1

2

High-throughput

0.445

High

542498

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.445

High

542608

RL36L
Ribosomal protein eL42-like

1

1

High-throughput

0.445

High

542676

GRHL1
Grainyhead-like protein 1 homolog

1

1

High-throughput

0.445

High

542693

AKP8L
A-kinase anchor protein 8-like

1

1

High-throughput

0.445

High

388959

FINC
Fibronectin

1

2

High-throughput

0.437

High

542547

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.437

High

542639

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

542647

CAD19
Cadherin-19

1

2

High-throughput

0.437

High

542652

MTRFR
Mitochondrial translation release factor in rescue

1

1

High-throughput

0.437

High

542692

HECD1
E3 ubiquitin-protein ligase HECTD1

1

6

High-throughput

0.437

High

542700

NINL
Ninein-like protein

1

1

High-throughput

0.437

High

542338

TYY1
Transcriptional repressor protein YY1

1

0

Small-scale

0.426

High

542465

XPC
DNA repair protein complementing XP-C cells

1

0

High-throughput

0.426

High

542482

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.426

High

542546

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.426

High

542385

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.408

High

107255

F8VR69
Ribosomal protein L6

1

1

High-throughput

0.407

High

542589

S20A1
Sodium-dependent phosphate transporter 1

1

1

High-throughput

0.407

High

542619

Q96KY9
CDH19 protein

1

2

High-throughput

0.407

High

542672

FBX28
F-box only protein 28

1

0

Small-scale

0.292

High

542330

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

0

High-throughput

0.279

Low

542407

SC61G
Protein transport protein Sec61 subunit gamma

1

0

High-throughput

0.279

Low

542480

VAC14
Protein VAC14 homolog

1

0

High-throughput

0.279

Low

542543

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

0

High-throughput

0.279

Low

542560

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

0

High-throughput

0.279

Low

542584

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.279

Low

542615

KBP
KIF-binding protein

1

0

High-throughput

0.279

Low

542657

RDD1
Required for drug-induced death protein 1

1

0

High-throughput

0.279

Low

542696

SSRG
Translocon-associated protein subunit gamma

1

0

High-throughput

0.279

Low

542583

FXL13
F-box and leucine-rich repeat protein 13

1

0

High-throughput

0.269

Low

542645

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.269

Low

336842

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

Small-scale

0.249

Low

542313

ITA4
Integrin alpha-4

1

0

High-throughput

0.249

Low

542512

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

542538

MINY4
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4

1

0

Small-scale

0.249

Low

542591

CLC4D
C-type lectin domain family 4 member D

1

0

High-throughput

0.249

Low

542641

ANO3
Anoctamin-3

1

0

High-throughput

0.249

Low

542669

DUOX2
Dual oxidase 2

1

0

High-throughput

0.249

Low

542549

SCMC2
Mitochondrial adenyl nucleotide antiporter SLC25A25

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025