Protein: AFAP1
Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110)

Gene: AFAP1
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q8N556

Gene Ontology (top 5):
GO:0001725 - stress fiber
GO:0003779 - actin binding
GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0015629 - actin cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1234149

ANLN
Anillin

3

1

High-throughput

0.847

High

161688

GAK
Cyclin-G-associated kinase

1

0

High-throughput

0.656

High

625516

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.656

High

397172

KPCG
Protein kinase C gamma type

1

5

Small-scale

0.647

High

408647

KPCB
Protein kinase C beta type

1

5

Small-scale

0.647

High

566428

KPCA
Protein kinase C alpha type

1

5

Small-scale

0.647

High

969097

KPCE
Protein kinase C epsilon type

1

5

Small-scale

0.647

High

984513

KPCD
Protein kinase C delta type

1

5

Small-scale

0.647

High

1234155

AKT3
RAC-gamma serine/threonine-protein kinase

1

3

High-throughput

0.618

High

835455

GSK3A
Glycogen synthase kinase-3 alpha

1

2

High-throughput

0.618

High

835881

GSK3B
Glycogen synthase kinase-3 beta

1

2

High-throughput

0.618

High

1234148

RHOF
Rho-related GTP-binding protein RhoF

1

1

High-throughput

0.618

High

1234139

AFAP1
Actin filament-associated protein 1

1

0

Small-scale

0.614

High

508101

FGFR1
Fibroblast growth factor receptor 1

1

0

Small-scale

0.586

High

894210

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.586

High

1066395

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.586

High

1234147

ECT2
Protein ECT2

1

0

High-throughput

0.586

High

369996

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

117762

MYO1C
Unconventional myosin-Ic

1

1

High-throughput

0.536

High

1234144

MYO19
Unconventional myosin-XIX

1

1

High-throughput

0.536

High

614383

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.515

High

598226

FLNA
Filamin-A

1

0

High-throughput

0.513

High

724916

MYH9
Myosin-9

1

0

High-throughput

0.513

High

809362

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

High-throughput

0.513

High

813102

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.513

High

906533

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

0

High-throughput

0.513

High

1077029

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

1085001

DREB
Drebrin

1

0

High-throughput

0.513

High

1232602

SYNPO
Synaptopodin

1

0

High-throughput

0.513

High

1234150

MYO5C
Unconventional myosin-Vc

1

0

High-throughput

0.513

High

1234153

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.513

High

1234154

TPX2
Targeting protein for Xklp2

1

0

High-throughput

0.513

High

1234140

MY18A
Unconventional myosin-XVIIIa

1

2

High-throughput

0.489

High

932259

ACTC
Actin, alpha cardiac muscle 1

1

0

Small-scale

0.480

High

210123

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

1234152

TES
Testin

1

1

High-throughput

0.479

High

897571

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.458

High

931734

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.458

High

1234145

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

1234146

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

308884

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.437

High

1046104

DX39B
Spliceosome RNA helicase DDX39B

1

1

Small-scale

0.437

High

1234141

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

497298

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

1032509

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.407

High

1234142

EXT2
Exostosin-2

2

0

High-throughput

0.328

High

347322

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.318

High

591373

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

0

High-throughput

0.279

Low

1234143

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.279

Low

233540

NUPR1
Nuclear protein 1

1

0

High-throughput

0.249

Low

608588

H1T
Histone H1t

1

0

High-throughput

0.249

Low

749674

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.249

Low

1170807

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1234151

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024