Protein: FAT4
Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)

Gene: FAT4
Organism: Homo sapiens
Interactions: 75
UniProt ID: Q6V0I7

Gene Ontology (top 5):
GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007157 - heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0021987 - cerebral cortex development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1250374

PCDGD
Protocadherin gamma-B1

2

20

High-throughput

0.811

High

761246

RYK
Tyrosine-protein kinase RYK

2

18

Small-scale

0.789

High

327008

NXPH2
Neurexophilin-2

3

12

High-throughput

0.770

High

1186208

CEA21
Cell adhesion molecule CEACAM21

3

14

High-throughput

0.770

High

1250370

PSG8
Pregnancy-specific beta-1-glycoprotein 8

2

13

High-throughput

0.726

High

731865

CEAM8
Cell adhesion molecule CEACAM8

1

13

High-throughput

0.691

High

533697

CLUS
Clusterin

2

1

High-throughput

0.628

High

62198

PRS37
Probable inactive serine protease 37

1

20

High-throughput

0.618

High

663554

CMA1
Chymase

1

20

High-throughput

0.618

High

363449

EGFR
Epidermal growth factor receptor

1

12

High-throughput

0.618

High

410909

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

17

High-throughput

0.618

High

1250361

CB048
Putative uncharacterized protein C2orf48

3

2

High-throughput

0.609

High

1250369

DKKL1
Dickkopf-like protein 1

3

9

High-throughput

0.604

High

480835

LEG1
Galectin-1

2

5

High-throughput

0.601

High

859877

RL28
Large ribosomal subunit protein eL28

2

6

High-throughput

0.601

High

61024

DCD2B
Doublecortin domain-containing protein 2B

2

1

High-throughput

0.574

High

70897

ZBBX
Zinc finger B-box domain-containing protein 1

2

3

High-throughput

0.574

High

869319

XCL1
Lymphotactin

2

5

High-throughput

0.574

High

1250353

IFNE
Interferon epsilon

2

2

High-throughput

0.574

High

123128

DX39A
ATP-dependent RNA helicase DDX39A

2

3

High-throughput

0.558

High

1250359

SPSB4
SPRY domain-containing SOCS box protein 4

2

20

High-throughput

0.549

High

1250368

XAGE1
X antigen family member 1

2

6

High-throughput

0.549

High

351832

BY55
CD160 antigen

1

6

High-throughput

0.536

High

504741

FBSP1
F-box/SPRY domain-containing protein 1

1

20

High-throughput

0.536

High

981866

RL23
Large ribosomal subunit protein uL14

1

13

High-throughput

0.536

High

1007871

X3CL1
Fractalkine

1

1

High-throughput

0.536

High

1250351

ATS13
A disintegrin and metalloproteinase with thrombospondin motifs 13

1

6

High-throughput

0.536

High

1250364

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

4

High-throughput

0.536

High

1250373

HYOU1
Hypoxia up-regulated protein 1

1

1

High-throughput

0.536

High

634771

GRAH
Granzyme H

1

20

High-throughput

0.514

High

516235

PAL4G
Peptidyl-prolyl cis-trans isomerase A-like 4G

2

2

High-throughput

0.504

High

989019

AP2B1
AP-2 complex subunit beta

1

2

High-throughput

0.501

High

969635

RS15A
Small ribosomal subunit protein uS8

1

0

High-throughput

0.493

High

66794

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

6

High-throughput

0.489

High

193287

SOCS1
Suppressor of cytokine signaling 1

1

11

High-throughput

0.489

High

261512

B4GT2
Beta-1,4-galactosyltransferase 2

1

2

High-throughput

0.489

High

376399

PDGFB
Platelet-derived growth factor subunit B

1

3

High-throughput

0.489

High

909056

NEK4
Serine/threonine-protein kinase Nek4

1

5

High-throughput

0.489

High

1088244

TCF15
Transcription factor 15

1

2

High-throughput

0.489

High

1204250

CAR16
Caspase recruitment domain-containing protein 16

1

1

High-throughput

0.489

High

1211577

C2D1B
Coiled-coil and C2 domain-containing protein 1B

1

2

High-throughput

0.489

High

1250354

LIX1L
LIX1-like protein

1

3

High-throughput

0.489

High

1250356

SIR6
NAD-dependent protein deacylase sirtuin-6

1

5

High-throughput

0.489

High

1250357

DCNP1
Dendritic cell nuclear protein 1

1

6

High-throughput

0.489

High

1250358

UCN3
Urocortin-3

1

2

High-throughput

0.489

High

1250360

LCFC1
Sperm-egg fusion protein LLCFC1

1

3

High-throughput

0.489

High

1250363

CCL19
C-C motif chemokine 19

1

5

High-throughput

0.489

High

1250365

CSTL1
Cystatin-like 1

1

2

High-throughput

0.489

High

1250371

DTX4
E3 ubiquitin-protein ligase DTX4

1

2

High-throughput

0.489

High

218351

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.479

High

466317

RHOC
Rho-related GTP-binding protein RhoC

1

13

High-throughput

0.479

High

774440

BASI
Basigin

1

4

High-throughput

0.479

High

787186

BMR1A
Bone morphogenetic protein receptor type-1A

1

1

High-throughput

0.479

High

861657

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

4

Small-scale

0.479

High

953517

RAC3
Ras-related C3 botulinum toxin substrate 3

1

12

High-throughput

0.479

High

955307

CDC42
Cell division control protein 42 homolog

1

13

High-throughput

0.479

High

962184

RHOA
Transforming protein RhoA

1

13

High-throughput

0.479

High

978100

RHOB
Rho-related GTP-binding protein RhoB

1

14

High-throughput

0.479

High

998460

H31
Histone H3.1

1

2

High-throughput

0.479

High

1028799

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

5

High-throughput

0.479

High

1250355

ARL14
ADP-ribosylation factor-like protein 14

1

1

High-throughput

0.479

High

1250367

RHOF
Rho-related GTP-binding protein RhoF

1

16

High-throughput

0.479

High

1250366

TNKS2
Poly [ADP-ribose] polymerase tankyrase-2

1

1

Small-scale

0.457

High

404142

GCR
Glucocorticoid receptor

1

2

High-throughput

0.437

High

1220578

RN123
E3 ubiquitin-protein ligase RNF123

1

2

High-throughput

0.437

High

1250350

UBP51
Ubiquitin carboxyl-terminal hydrolase 51

1

4

Small-scale

0.437

High

1250372

TRRAP
Transformation/transcription domain-associated protein

1

2

High-throughput

0.437

High

117833

DCDC1
Doublecortin domain-containing protein 1

1

1

High-throughput

0.407

High

183666

RT12
Small ribosomal subunit protein uS12m

1

5

High-throughput

0.407

High

1250362

SPSB2
SPRY domain-containing SOCS box protein 2

1

20

High-throughput

0.407

High

903078

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2

2

0

High-throughput

0.328

High

598746

ANFB
Natriuretic peptides B

1

0

High-throughput

0.279

Low

1250352

TAFA5
Chemokine-like protein TAFA-5

1

0

High-throughput

0.279

Low

596176

H12
Histone H1.2

1

0

High-throughput

0.269

Low

927364

ATX1
Ataxin-1

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025