Protein: AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)

Gene: AGAP2
Organism: Mus musculus
Interactions: 231
UniProt ID: Q3UHD9

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005096 - GTPase activator activity
GO:0005524 - ATP binding
GO:0005525 - GTP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

99969

SYGP1
Ras/Rap GTPase-activating protein SynGAP

3

19

High-throughput

0.861

High

1112568

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

3

9

High-throughput

0.861

High

1112581

DLG4
Disks large homolog 4

3

10

High-throughput

0.861

High

1112594

NEB2
Neurabin-2

3

16

High-throughput

0.847

High

949275

TNIK
Traf2 and NCK-interacting protein kinase

2

7

High-throughput

0.811

High

1112606

CNKR2
Connector enhancer of kinase suppressor of ras 2

2

11

High-throughput

0.811

High

57843

KALRN
Kalirin

1

9

High-throughput

0.691

High

70554

B2RQ57
Tyrosine-protein kinase

1

16

High-throughput

0.691

High

88367

SHAN1
SH3 and multiple ankyrin repeat domains protein 1

1

7

High-throughput

0.691

High

103599

ANK3
Ankyrin-3

1

1

High-throughput

0.691

High

222418

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.691

High

250713

E41L2
Band 4.1-like protein 2

1

7

High-throughput

0.691

High

397212

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

5

High-throughput

0.691

High

403434

SRC
Proto-oncogene tyrosine-protein kinase Src

1

16

High-throughput

0.691

High

515228

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

8

High-throughput

0.691

High

554904

KPCE
Protein kinase C epsilon type

1

9

High-throughput

0.691

High

659450

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

8

High-throughput

0.691

High

682468

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

4

High-throughput

0.691

High

710137

FAK1
Focal adhesion kinase 1

1

20

High-throughput

0.691

High

760445

DYN1
Dynamin-1

1

1

High-throughput

0.691

High

829604

CDK5
Cyclin-dependent kinase 5

1

1

High-throughput

0.691

High

886878

RHG39
Rho GTPase-activating protein 39

1

10

High-throughput

0.691

High

892722

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.691

High

926406

MK01
Mitogen-activated protein kinase 1

1

5

High-throughput

0.691

High

930565

KPCG
Protein kinase C gamma type

1

15

High-throughput

0.691

High

933107

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

5

High-throughput

0.691

High

934623

KPCB
Protein kinase C beta type

1

9

High-throughput

0.691

High

956169

NPTN
Neuroplastin

1

3

High-throughput

0.691

High

956268

PKP1
Plakophilin-1

1

2

High-throughput

0.691

High

980214

NF1
Neurofibromin

1

18

High-throughput

0.691

High

1002014

TRIO
Triple functional domain protein

1

12

High-throughput

0.691

High

1112542

DAB2P
Disabled homolog 2-interacting protein

1

19

High-throughput

0.691

High

1112565

IQGA2
Ras GTPase-activating-like protein IQGAP2

1

19

High-throughput

0.691

High

1112566

SRBS2
Sorbin and SH3 domain-containing protein 2

1

20

High-throughput

0.691

High

1112571

PRAG1
Inactive tyrosine-protein kinase PRAG1

1

6

High-throughput

0.691

High

1112579

GDIB
Rab GDP dissociation inhibitor beta

1

2

High-throughput

0.691

High

1112583

SRBS1
Sorbin and SH3 domain-containing protein 1

1

20

High-throughput

0.691

High

1112584

MK03
Mitogen-activated protein kinase 3

1

5

High-throughput

0.691

High

1112588

RGPA1
Ral GTPase-activating protein subunit alpha-1

1

4

High-throughput

0.691

High

1112589

SIK3
Serine/threonine-protein kinase SIK3

1

1

High-throughput

0.691

High

1112590

ARHGI
Rho guanine nucleotide exchange factor 18

1

8

High-throughput

0.691

High

1112593

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

8

High-throughput

0.691

High

1112597

TLN2
Talin-2

1

5

High-throughput

0.691

High

1112603

LRRC7
Leucine-rich repeat-containing protein 7

1

2

High-throughput

0.691

High

1112605

C170B
Centrosomal protein of 170 kDa protein B

1

4

High-throughput

0.691

High

1112609

NRCAM
Neuronal cell adhesion molecule

1

2

High-throughput

0.691

High

1112611

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

1

8

High-throughput

0.691

High

1112613

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

6

High-throughput

0.691

High

1112618

PKN2
Serine/threonine-protein kinase N2

1

11

High-throughput

0.691

High

1112619

TENR
Tenascin-R

1

4

High-throughput

0.691

High

1112621

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

1

5

High-throughput

0.691

High

1112622

ANK2
Ankyrin-2

1

1

High-throughput

0.691

High

1112624

ASPP2
Apoptosis-stimulating of p53 protein 2

1

4

High-throughput

0.691

High

1112625

RPGF2
Rap guanine nucleotide exchange factor 2

1

13

High-throughput

0.691

High

1112628

DP13A
DCC-interacting protein 13-alpha

1

14

High-throughput

0.691

High

1112637

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

9

High-throughput

0.691

High

1112640

MYO5A
Unconventional myosin-Va

1

2

High-throughput

0.691

High

1112642

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

11

High-throughput

0.691

High

1112647

RPGF4
Rap guanine nucleotide exchange factor 4

1

12

High-throughput

0.691

High

1112648

RIMS2
Regulating synaptic membrane exocytosis protein 2

1

12

High-throughput

0.691

High

1112651

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

19

High-throughput

0.691

High

1112653

DCLK1
Serine/threonine-protein kinase DCLK1

1

20

High-throughput

0.691

High

1112658

ASAP1
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

1

16

High-throughput

0.691

High

1112664

PCLO
Protein piccolo

1

11

High-throughput

0.691

High

1112666

GSK3B
Glycogen synthase kinase-3 beta

1

3

High-throughput

0.691

High

1112667

E41L3
Band 4.1-like protein 3

1

7

High-throughput

0.691

High

1112670

RASL1
RasGAP-activating-like protein 1

1

18

High-throughput

0.691

High

1112671

E41L1
Band 4.1-like protein 1

1

7

High-throughput

0.691

High

1112644

DLGP1
Disks large-associated protein 1

3

7

High-throughput

0.667

High

1112599

CYFP1
Cytoplasmic FMR1-interacting protein 1

2

1

High-throughput

0.628

High

1112673

HOME1
Homer protein homolog 1

2

6

High-throughput

0.628

High

192274

NCAM2
Neural cell adhesion molecule 2

1

5

High-throughput

0.618

High

82757

B9EKJ1
Spna2 protein

1

7

High-throughput

0.618

High

103620

G5E8K8
AHNAK nucleoprotein

1

1

High-throughput

0.618

High

110602

H3BJX1
Ecotropic viral integration site 5 like

1

2

High-throughput

0.618

High

546273

INSR
Insulin receptor

1

13

Small-scale

0.618

High

593482

KPCA
Protein kinase C alpha type

1

9

High-throughput

0.618

High

936177

DLG3
Disks large homolog 3

1

8

High-throughput

0.618

High

936317

DCC
Netrin receptor DCC

1

3

Small-scale

0.618

High

956597

RGS14
Regulator of G-protein signaling 14

1

3

High-throughput

0.618

High

995940

PRLR
Prolactin receptor

1

4

Small-scale

0.618

High

1012208

Q0VAV5
RAS protein activator like 2

1

19

High-throughput

0.618

High

1112580

MK10
Mitogen-activated protein kinase 10

1

7

High-throughput

0.618

High

1112586

GIT1
ARF GTPase-activating protein GIT1

1

15

High-throughput

0.618

High

1112600

Q7TN74
Neurabin I

1

18

High-throughput

0.618

High

1112610

DLG1
Disks large homolog 1

1

8

High-throughput

0.618

High

1112626

UNC5B
Netrin receptor UNC5B

1

1

Small-scale

0.618

High

1112634

LNX2
Ligand of Numb protein X 2

1

12

High-throughput

0.618

High

1112635

DLG2
Disks large homolog 2

1

8

High-throughput

0.618

High

1112639

GRIP1
Glutamate receptor-interacting protein 1

1

18

Small-scale

0.618

High

1112654

MINK1
Misshapen-like kinase 1

1

6

High-throughput

0.618

High

1112655

FAK2
Protein-tyrosine kinase 2-beta

1

20

High-throughput

0.618

High

620948

GRIA2
Glutamate receptor 2

2

9

Small-scale

0.611

High

88312

D3YUZ8
Discs large MAGUK scaffold protein 2

1

8

High-throughput

0.575

High

90327

E0CZD7
non-specific serine/threonine protein kinase

1

5

High-throughput

0.575

High

93233

E9PW37
RAS protein activator like 2

1

19

High-throughput

0.575

High

93394

E9Q2A6
non-specific protein-tyrosine kinase

1

20

High-throughput

0.575

High

93652

E9Q616
AHNAK nucleoprotein

1

6

High-throughput

0.575

High

100217

F7AMS7
non-specific serine/threonine protein kinase

1

8

High-throughput

0.575

High

110604

H3BKQ3
Ecotropic viral integration site 5 like

1

2

High-throughput

0.575

High

110605

H3BL28
Protein phosphatase 1, regulatory subunit 9A

1

19

High-throughput

0.575

High

561159

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

7

High-throughput

0.575

High

1112027

Q3TQZ7
Stress-activated protein kinase JNK

1

7

High-throughput

0.575

High

1112569

Q4VA93
Protein kinase C

1

9

High-throughput

0.575

High

1112570

Q52KF7
Discs large MAGUK scaffold protein 3

1

8

High-throughput

0.575

High

1112574

Q5F258
GIT ArfGAP 1

1

15

High-throughput

0.575

High

1112660

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4

1

7

High-throughput

0.575

High

70621

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

6

High-throughput

0.536

High

139119

DPYL2
Dihydropyrimidinase-related protein 2

1

1

High-throughput

0.536

High

139555

STXB1
Syntaxin-binding protein 1

1

3

High-throughput

0.536

High

140097

NUMBL
Numb-like protein

1

8

High-throughput

0.536

High

193603

PITM1
Membrane-associated phosphatidylinositol transfer protein 1

1

1

High-throughput

0.536

High

223077

STRN
Striatin

1

1

High-throughput

0.536

High

223116

SEPT7
Septin-7

1

10

High-throughput

0.536

High

250851

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

1

6

High-throughput

0.536

High

440266

NFL
Neurofilament light polypeptide

1

2

High-throughput

0.536

High

440291

NFM
Neurofilament medium polypeptide

1

2

High-throughput

0.536

High

525130

GELS
Gelsolin

1

1

High-throughput

0.536

High

567499

AP2A1
AP-2 complex subunit alpha-1

1

5

High-throughput

0.536

High

567523

AP2A2
AP-2 complex subunit alpha-2

1

5

High-throughput

0.536

High

579647

GNAO

1

5

High-throughput

0.536

High

597629

GNA11
Guanine nucleotide-binding protein subunit alpha-11

1

6

High-throughput

0.536

High

597633

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

6

High-throughput

0.536

High

649244

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

5

High-throughput

0.536

High

723527

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

10

High-throughput

0.536

High

723576

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

10

High-throughput

0.536

High

804942

AINX
Alpha-internexin

1

3

High-throughput

0.536

High

808350

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

2

High-throughput

0.536

High

819131

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

1

3

High-throughput

0.536

High

885077

ACTN4
Alpha-actinin-4

1

4

High-throughput

0.536

High

906249

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

High-throughput

0.536

High

906649

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

1

High-throughput

0.536

High

921090

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

3

High-throughput

0.536

High

921798

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

3

High-throughput

0.536

High

930604

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

4

High-throughput

0.536

High

956443

DPYL1
Dihydropyrimidinase-related protein 1

1

1

High-throughput

0.536

High

956895

GRM1
Metabotropic glutamate receptor 1

1

5

High-throughput

0.536

High

963721

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

10

High-throughput

0.536

High

975398

ENAH
Protein enabled homolog

1

10

High-throughput

0.536

High

1061831

GRM2
Metabotropic glutamate receptor 2

1

5

High-throughput

0.536

High

1111845

IQEC3
IQ motif and SEC7 domain-containing protein 3

1

2

High-throughput

0.536

High

1112567

GRM5
Metabotropic glutamate receptor 5

1

5

High-throughput

0.536

High

1112573

IQEC2
IQ motif and SEC7 domain-containing protein 2

1

3

High-throughput

0.536

High

1112575

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

1

High-throughput

0.536

High

1112582

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

7

High-throughput

0.536

High

1112585

CLH1
Clathrin heavy chain 1

1

1

High-throughput

0.536

High

1112587

Q68FG2
Spectrin beta chain

1

6

High-throughput

0.536

High

1112595

PI5L1
Phosphatidylinositol 4-phosphate 5-kinase-like protein 1

1

1

High-throughput

0.536

High

1112598

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

High-throughput

0.536

High

1112601

ACTN1
Alpha-actinin-1

1

4

High-throughput

0.536

High

1112602

MAP6
Microtubule-associated protein 6

1

7

High-throughput

0.536

High

1112607

MYOME
Myomegalin

1

4

High-throughput

0.536

High

1112608

SHAN2
SH3 and multiple ankyrin repeat domains protein 2

1

18

High-throughput

0.536

High

1112614

DLGP2
Disks large-associated protein 2

1

7

High-throughput

0.536

High

1112616

LIPA2
Liprin-alpha-2

1

6

High-throughput

0.536

High

1112629

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

3

High-throughput

0.536

High

1112631

LUZP1
Leucine zipper protein 1

1

3

High-throughput

0.536

High

1112632

WASF1
Actin-binding protein WASF1

1

4

High-throughput

0.536

High

1112638

ATAD3
ATPase family AAA domain-containing protein 3

1

1

High-throughput

0.536

High

1112645

AP2B1
AP-2 complex subunit beta

1

5

High-throughput

0.536

High

1112646

NBEA
Neurobeachin

1

4

High-throughput

0.536

High

1112656

SRCN1
SRC kinase signaling inhibitor 1

1

3

High-throughput

0.536

High

1112659

DREB
Drebrin

1

7

High-throughput

0.536

High

1112662

MAP1A
Microtubule-associated protein 1A

1

5

High-throughput

0.536

High

1112663

GRM3
Metabotropic glutamate receptor 3

1

5

High-throughput

0.536

High

1112672

SEPT5
Septin-5

1

10

High-throughput

0.536

High

786652

STA5A
Signal transducer and activator of transcription 5A

1

3

Small-scale

0.515

High

99872

F6QQP6
Disabled 2 interacting protein

1

19

High-throughput

0.514

High

100127

F6UDT8
Discs large MAGUK scaffold protein 1

1

16

High-throughput

0.514

High

70579

B2RQG2
PHD finger protein 3

1

0

High-throughput

0.513

High

427720

ANXA2
Annexin A2

1

0

High-throughput

0.513

High

534613

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

0

High-throughput

0.513

High

543095

GLNA
Glutamine synthetase

1

0

High-throughput

0.513

High

572248

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.513

High

659511

NCKP1
Nck-associated protein 1

1

0

High-throughput

0.513

High

869930

CACB3
Voltage-dependent L-type calcium channel subunit beta-3

1

0

High-throughput

0.513

High

936717

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

0

High-throughput

0.513

High

1101881

PHAR1
Phosphatase and actin regulator 1

1

0

High-throughput

0.513

High

1112604

PPM1E
Protein phosphatase 1E

1

0

High-throughput

0.513

High

1112617

GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase

1

0

High-throughput

0.513

High

1112627

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.513

High

1112630

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

0

High-throughput

0.513

High

1112633

PQBP1
Polyglutamine-binding protein 1

1

0

High-throughput

0.513

High

1112636

KAD5
Adenylate kinase isoenzyme 5

1

0

High-throughput

0.513

High

1112649

UBE4B
Ubiquitin conjugation factor E4 B

1

0

High-throughput

0.513

High

1112650

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

0

High-throughput

0.513

High

1112652

SACS
Sacsin

1

0

High-throughput

0.513

High

1112665

ARC1A
Actin-related protein 2/3 complex subunit 1A

1

0

High-throughput

0.513

High

1112668

NCDN
Neurochondrin

1

0

High-throughput

0.513

High

291683

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

1

High-throughput

0.489

High

1112572

KCD16
BTB/POZ domain-containing protein KCTD16

1

2

High-throughput

0.489

High

1112591

ANM8
Protein arginine N-methyltransferase 8

1

1

High-throughput

0.489

High

1112596

SYNE1
Nesprin-1

1

5

High-throughput

0.489

High

69913

DLGP4
Disks large-associated protein 4

1

7

High-throughput

0.479

High

71323

B2RXW8
Ppfia1 protein

1

6

High-throughput

0.479

High

193238

AP1B1
AP-1 complex subunit beta-1

1

5

High-throughput

0.479

High

620886

GRIA1
Glutamate receptor 1

1

7

High-throughput

0.479

High

679423

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

1

5

High-throughput

0.479

High

1112592

DLGP3
Disks large-associated protein 3

1

7

High-throughput

0.479

High

1112615

Q8BPK8
Agenet-like domain-containing protein

1

5

High-throughput

0.479

High

1112620

NLGN3
Neuroligin-3

1

4

High-throughput

0.479

High

1112641

NLGN1
Neuroligin-1

1

4

High-throughput

0.479

High

1112643

CNTP2
Contactin-associated protein-like 2

1

3

High-throughput

0.479

High

1112657

HOME2
Homer protein homolog 2

1

6

High-throughput

0.479

High

1112669

GNAS3
Neuroendocrine secretory protein 55

1

0

High-throughput

0.458

High

69466

NLGN4
Neuroligin 4-like

1

4

High-throughput

0.445

High

69800

B1AS06
DLG associated protein 3

1

7

High-throughput

0.445

High

81951

B7ZNS2
DLG associated protein 4

1

7

High-throughput

0.445

High

82314

B8QI33
Liprin-alpha 1

1

6

High-throughput

0.445

High

90326

E0CZ78
Serine/threonine-protein phosphatase

1

3

High-throughput

0.445

High

93500

E9Q4F9
Homer scaffolding protein 2

1

5

High-throughput

0.445

High

93788

E9QK34
Neuroligin 1

1

4

High-throughput

0.445

High

729465

FMR1
Fragile X messenger ribonucleoprotein 1

1

5

High-throughput

0.445

High

926665

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

5

High-throughput

0.445

High

412

A0A087WS83
Voltage-dependent R-type calcium channel subunit alpha

1

2

High-throughput

0.437

High

88454

D3Z656
phosphoinositide 5-phosphatase

1

2

High-throughput

0.437

High

93400

E9Q2S0
Protocadherin 7

1

10

High-throughput

0.437

High

1112577

SC6A4
Sodium-dependent serotonin transporter

1

3

High-throughput

0.437

High

1112612

Q8BH80
Vesicle-associated membrane protein, associated protein B and C

1

1

High-throughput

0.437

High

1112623

Q8CFX3
Protocadherin 1

1

6

High-throughput

0.437

High

2045

A0A0A6YY83
Protocadherin 7

1

10

High-throughput

0.407

High

57109

A2AGI3
Neuroligin 3

1

4

High-throughput

0.407

High

90307

E0CXD4
Protocadherin 1

1

6

High-throughput

0.407

High

93707

E9Q7S0
phosphoinositide 5-phosphatase

1

3

High-throughput

0.407

High

93828

E9QMC2
Glutamate receptor, metabotropic 5

1

6

High-throughput

0.407

High

100188

F6YNQ1
Glutamate receptor

1

7

High-throughput

0.407

High

110603

H3BK84
Protein kinase, cAMP dependent regulatory, type II beta

1

3

High-throughput

0.407

High

1112576

Q5SVG5
AP complex subunit beta

1

5

High-throughput

0.407

High

1112578

CAC1E
Voltage-dependent R-type calcium channel subunit alpha-1E

1

2

High-throughput

0.407

High

1112661

VAPB
Vesicle-associated membrane protein-associated protein B

1

1

High-throughput

0.407

High

91019

MTCL2
Microtubule cross-linking factor 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024