Protein: ATG12
Ubiquitin-like protein ATG12 (Autophagy-related protein 12) (APG12-like)

Gene: ATG12
Organism: Homo sapiens
Interactions: 119
UniProt ID: O94817

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000421 - autophagosome membrane
GO:0005654 - nucleoplasm
GO:0005776 - autophagosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

296761

ATG5
Autophagy protein 5

10

3

Small-scale

0.975

High

296769

ATG3
Ubiquitin-like-conjugating enzyme ATG3

14

6

Small-scale

0.761

High

296733

A16L1
Autophagy-related protein 16-1

9

1

Small-scale

0.755

High

296760

ATG10
Ubiquitin-like-conjugating enzyme ATG10

5

6

Small-scale

0.718

High

296737

TCPR1
Tectonin beta-propeller repeat-containing protein 1

4

0

Small-scale

0.664

High

296684

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

3

3

Small-scale

0.664

High

296741

RBCC1
RB1-inducible coiled-coil protein 1

3

2

Small-scale

0.656

High

296781

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

2

1

Small-scale

0.584

High

296722

SRTD2
SERTA domain-containing protein 2

2

0

High-throughput

0.580

High

296754

IER2
Immediate early response gene 2 protein

2

0

High-throughput

0.580

High

296704

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

Small-scale

0.537

High

280836

KRT37
Keratin, type I cuticular Ha7

1

2

High-throughput

0.536

High

296683

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

3

High-throughput

0.536

High

296717

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

1

1

High-throughput

0.536

High

296759

RB33B
Ras-related protein Rab-33B

1

2

High-throughput

0.536

High

170012

PLS1
Phospholipid scramblase 1

1

0

High-throughput

0.518

High

296751

KR412
Keratin-associated protein 4-12

1

0

High-throughput

0.518

High

296757

DOCK9
Dedicator of cytokinesis protein 9

1

0

High-throughput

0.518

High

296695

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.513

High

296699

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.513

High

296706

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.513

High

296709

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.513

High

296711

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.513

High

296742

CCD12
Coiled-coil domain-containing protein 12

1

0

High-throughput

0.513

High

296745

EXOC4
Exocyst complex component 4

1

0

Small-scale

0.513

High

296780

ATG4B
Cysteine protease ATG4B

1

0

High-throughput

0.513

High

296685

RIGI
Antiviral innate immune response receptor RIG-I

1

1

Small-scale

0.500

High

296756

IFIH1
Interferon-induced helicase C domain-containing protein 1

1

1

Small-scale

0.500

High

268552

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.493

High

296712

OTUD4
OTU domain-containing protein 4

1

0

High-throughput

0.493

High

296728

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.493

High

296739

WDFY3
WD repeat and FYVE domain-containing protein 3

1

0

Small-scale

0.493

High

296763

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

0

High-throughput

0.493

High

296784

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

0

High-throughput

0.493

High

296721

RB33A
Ras-related protein Rab-33A

1

2

High-throughput

0.489

High

296714

FAK1
Focal adhesion kinase 1

1

1

High-throughput

0.481

High

296686

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

159817

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

1

High-throughput

0.479

High

162280

XPO1
Exportin-1

1

1

High-throughput

0.479

High

262207

ULK1
Serine/threonine-protein kinase ULK1

1

1

Small-scale

0.479

High

296688

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

2

High-throughput

0.479

High

296690

BCL2
Apoptosis regulator Bcl-2

1

1

Small-scale

0.479

High

296694

LMNB1
Lamin-B1

1

1

High-throughput

0.479

High

296696

DDX6
Probable ATP-dependent RNA helicase DDX6

1

1

High-throughput

0.479

High

296702

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

2

High-throughput

0.479

High

296710

RL11
Large ribosomal subunit protein uL5

1

1

High-throughput

0.479

High

296715

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

1

1

Small-scale

0.479

High

296718

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

1

High-throughput

0.479

High

296719

FADD
FAS-associated death domain protein

1

1

Small-scale

0.479

High

296720

GOGA4
Golgin subfamily A member 4

1

1

High-throughput

0.479

High

296723

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

1

High-throughput

0.479

High

296726

GOGB1
Golgin subfamily B member 1

1

1

High-throughput

0.479

High

296727

K1H1
Keratin, type I cuticular Ha1

1

2

High-throughput

0.479

High

296730

CDC37
Hsp90 co-chaperone Cdc37

1

1

High-throughput

0.479

High

296738

GCC2
GRIP and coiled-coil domain-containing protein 2

1

2

High-throughput

0.479

High

296749

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

1

High-throughput

0.479

High

296758

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

3

High-throughput

0.479

High

296771

GGA3
ADP-ribosylation factor-binding protein GGA3

1

1

High-throughput

0.479

High

296776

SNX6
Sorting nexin-6

1

1

High-throughput

0.479

High

296783

SNX5
Sorting nexin-5

1

1

High-throughput

0.479

High

296734

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

117939

SNP23
Synaptosomal-associated protein 23

1

0

High-throughput

0.458

High

177637

BIRC5
Baculoviral IAP repeat-containing protein 5

1

0

Small-scale

0.458

High

255013

ATG13
Autophagy-related protein 13

1

0

Small-scale

0.458

High

261058

SH3L1
Adapter SH3BGRL

1

0

Small-scale

0.458

High

275614

POP7
Ribonuclease P protein subunit p20

1

0

High-throughput

0.458

High

276126

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

0

Small-scale

0.458

High

296689

RU2B
U2 small nuclear ribonucleoprotein B''

1

0

High-throughput

0.458

High

296693

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

296705

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

High-throughput

0.458

High

296707

RS29
Small ribosomal subunit protein uS14

1

0

High-throughput

0.458

High

296708

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

296713

CAV1
Caveolin-1

1

0

Small-scale

0.458

High

296716

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

0

High-throughput

0.458

High

296724

FLOT2
Flotillin-2

1

0

High-throughput

0.458

High

296740

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

296744

ESR2
Estrogen receptor beta

1

0

Small-scale

0.458

High

296747

VP13A
Intermembrane lipid transfer protein VPS13A

1

0

High-throughput

0.458

High

296748

PHB2
Prohibitin-2

1

0

High-throughput

0.458

High

296753

ATGA1
Autophagy-related protein 101

1

0

Small-scale

0.458

High

296755

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

0

High-throughput

0.458

High

296765

MOV10
Helicase MOV-10

1

0

High-throughput

0.458

High

296766

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.458

High

296767

KRT82
Keratin, type II cuticular Hb2

1

0

High-throughput

0.458

High

296768

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

296772

TAP26
Thyroid transcription factor 1-associated protein 26

1

0

High-throughput

0.458

High

296773

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.458

High

296778

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.458

High

296779

CHTOP
Chromatin target of PRMT1 protein

1

0

High-throughput

0.458

High

296701

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

296687

ATPB
ATP synthase subunit beta, mitochondrial

1

2

High-throughput

0.437

High

296782

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

1

High-throughput

0.437

High

296698

HD
Huntingtin

1

0

Small-scale

0.426

High

296725

BECN1
Beclin-1

1

0

High-throughput

0.426

High

296732

Q5VVC8
Large ribosomal subunit protein uL5

1

1

High-throughput

0.407

High

296775

SRTD1
SERTA domain-containing protein 1

2

0

High-throughput

0.316

High

296736

MAVS
Mitochondrial antiviral-signaling protein

2

0

Small-scale

0.310

High

197640

CRX
Cone-rod homeobox protein

1

0

High-throughput

0.299

High

296750

MDFI
MyoD family inhibitor

1

0

High-throughput

0.282

High

202798

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.279

Low

296752

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.279

Low

168311

SCAM1
Secretory carrier-associated membrane protein 1

1

0

High-throughput

0.249

Low

202702

TPD54
Tumor protein D54

1

0

High-throughput

0.249

Low

280167

CBPD
Carboxypeptidase D

1

0

High-throughput

0.249

Low

296692

MPRI
Cation-independent mannose-6-phosphate receptor

1

0

High-throughput

0.249

Low

296697

EPHA2
Ephrin type-A receptor 2

1

0

High-throughput

0.249

Low

296700

NUMB
Protein numb homolog

1

0

High-throughput

0.249

Low

296703

S12A2
Solute carrier family 12 member 2

1

0

High-throughput

0.249

Low

296729

RM23
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.249

Low

296731

RNFT1
E3 ubiquitin-protein ligase RNFT1

1

0

High-throughput

0.249

Low

296735

EBLN2
Endogenous Bornavirus-like nucleoprotein 2

1

0

High-throughput

0.249

Low

296743

CANT1
Soluble calcium-activated nucleotidase 1

1

0

High-throughput

0.249

Low

296746

Q96F87
TOG domain-containing protein

1

0

High-throughput

0.249

Low

296762

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

0

High-throughput

0.249

Low

296764

MRM3
rRNA methyltransferase 3, mitochondrial

1

0

High-throughput

0.249

Low

296770

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.249

Low

296774

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.249

Low

296777

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.249

Low

296691

RALB
Ras-related protein Ral-B

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024