Protein: SEM1A
Semaphorin-1A (Semaphorin-I) (Sema I)

Gene: SEM1A, Sema1a
Organism: Drosophila melanogaster
Interactions: 157
UniProt ID: Q24322

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0007411 - axon guidance
GO:0007416 - synapse assembly
GO:0008039 - synaptic target recognition
GO:0008045 - motor neuron axon guidance

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1071102

Q0KIF1
Plexin A, isoform B

4

20

Small-scale

0.882

High

1173627

SEM1A
Semaphorin-1A

1

15

Small-scale

0.710

High

855994

MOEH
Moesin/ezrin/radixin homolog 1

2

0

Small-scale

0.588

High

1173655

Q9U7D8
FI23202p1

2

1

Small-scale

0.584

High

628983

NRG
Neuroglian

1

5

High-throughput

0.575

High

1173639

Q7KT16
FI17352p1

1

7

Small-scale

0.552

High

1173672

FLNA
Filamin-A

1

4

Small-scale

0.552

High

52520

A1Z6Z9
Dilute class unconventional myosin, isoform A

1

1

High-throughput

0.536

High

54420

A1Z8J5
Shavenoid, isoform A

1

1

High-throughput

0.536

High

262788

TENM
Teneurin-m

1

2

High-throughput

0.536

High

479718

INSR
Insulin-like receptor

1

14

High-throughput

0.536

High

709531

1433Z
14-3-3 protein zeta

1

3

High-throughput

0.536

High

746482

CYA1
Adenylate cyclase 1

1

3

High-throughput

0.536

High

753708

FAT
Cadherin-related tumor suppressor

1

5

High-throughput

0.536

High

778189

PTP10
Tyrosine-protein phosphatase 10D

1

4

High-throughput

0.536

High

1019232

P91634
phosphatidylinositol 3-kinase

1

6

High-throughput

0.536

High

1173629

RYR
Ryanodine receptor

1

3

High-throughput

0.536

High

1173654

DOM
Helicase domino

1

3

High-throughput

0.536

High

1173677

CADN2
Putative neural-cadherin 2

1

5

High-throughput

0.536

High

1173680

TOR
Serine/threonine-protein kinase mTor

1

12

High-throughput

0.536

High

1173691

Q9VPL9
FI24801p1

1

3

High-throughput

0.536

High

1173704

EXOC1
Exocyst complex component 1

1

1

High-throughput

0.536

High

1173706

FAT2
Fat-like cadherin-related tumor suppressor homolog

1

6

High-throughput

0.536

High

1173714

HOBIT
Protein hobbit

1

1

High-throughput

0.536

High

1173719

STUM
Protein stum

1

1

High-throughput

0.536

High

1173724

Q9W451
Female sterile

1

1

High-throughput

0.536

High

1173727

FUTSC
Microtubule-associated protein futsch

1

10

High-throughput

0.536

High

1173631

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

0

High-throughput

0.513

High

1173634

PTK7
Tyrosine-protein kinase-like otk

1

6

Small-scale

0.501

High

355879

O96681
Plexin A

1

20

High-throughput

0.492

High

56056

A1Z9S6

1

9

High-throughput

0.489

High

57048

A1ZAN6
Rho guanine nucleotide exchange factor 2, isoform D

1

2

High-throughput

0.489

High

57182

A1ZAV3
Misexpression suppressor of ras 4, isoform A

1

2

High-throughput

0.489

High

263812

CLOCK
Circadian locomoter output cycles protein kaput

1

1

High-throughput

0.489

High

705008

EXU
Maternal protein exuperantia

1

1

High-throughput

0.489

High

828074

LA
La protein homolog

1

1

High-throughput

0.489

High

852487

CADF
Cofilin/actin-depolymerizing factor homolog

1

1

High-throughput

0.489

High

875348

DIA
Protein diaphanous

1

1

High-throughput

0.489

High

900583

TAF1
Transcription initiation factor TFIID subunit 1

1

2

High-throughput

0.489

High

904450

HYD
E3 ubiquitin-protein ligase hyd

1

2

High-throughput

0.489

High

1070138

Q0E9F3
FI03652p

1

1

High-throughput

0.489

High

1173628

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

3

High-throughput

0.489

High

1173630

XPC
DNA repair protein complementing XP-C cells homolog

1

5

High-throughput

0.489

High

1173632

Q3YMU0
Protein disulfide-isomerase

1

3

High-throughput

0.489

High

1173633

ATM
Serine/threonine-protein kinase ATM

1

9

High-throughput

0.489

High

1173636

Q7JVH6
LD24696p

1

1

High-throughput

0.489

High

1173637

Q7K4X4
GH24095p

1

3

High-throughput

0.489

High

1173638

Q7KND8
FI09619p

1

1

High-throughput

0.489

High

1173641

TRA1
Transcription-associated protein 1

1

9

High-throughput

0.489

High

1173647

LVA
Protein lava lamp

1

3

High-throughput

0.489

High

1173649

Q8SX22
RE68725p

1

9

High-throughput

0.489

High

1173652

Q961C4
LD23619p

1

1

High-throughput

0.489

High

1173656

Q9V3M9
Tektin

1

2

High-throughput

0.489

High

1173658

APLP
Apolipophorins

1

1

High-throughput

0.489

High

1173660

PREP
Presequence protease, mitochondrial

1

2

High-throughput

0.489

High

1173661

SRRT
Serrate RNA effector molecule homolog

1

1

High-throughput

0.489

High

1173662

Q9VA69
procollagen-proline 4-dioxygenase

1

1

High-throughput

0.489

High

1173663

Q9VAV5
Dynein-1, subspecies f

1

8

High-throughput

0.489

High

1173668

ANKHM
Ankyrin repeat and KH domain-containing protein mask

1

1

High-throughput

0.489

High

1173669

Q9VCE2
LD03179p

1

1

High-throughput

0.489

High

1173670

Q9VDG0
Dynein heavy chain at 93AB, isoform B

1

8

High-throughput

0.489

High

1173673

Q9VF02
Helicase 89B, isoform B

1

7

High-throughput

0.489

High

1173674

Q9VFF0
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.489

High

1173675

Q9VH10
TBC1 domain family member 30

1

3

High-throughput

0.489

High

1173676

Q9VJ35
LD01527p

1

6

High-throughput

0.489

High

1173678

Q9VJC3
Cilia- and flagella-associated protein 91

1

1

High-throughput

0.489

High

1173679

CL190
Restin homolog

1

3

High-throughput

0.489

High

1173681

MPND
MPN domain-containing protein CG4751

1

1

High-throughput

0.489

High

1173682

C2D1
Coiled-coil and C2 domain-containing protein 1-like

1

2

High-throughput

0.489

High

1173683

POE
Protein purity of essence

1

3

High-throughput

0.489

High

1173684

Q9VM37
FI17813p1

1

1

High-throughput

0.489

High

1173685

Q9VM62
LD34181p

1

2

High-throughput

0.489

High

1173686

Q9VME5
Slow as molasses, isoform B

1

1

High-throughput

0.489

High

1173688

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

8

High-throughput

0.489

High

1173689

Q9VNH2
GM13341p

1

1

High-throughput

0.489

High

1173692

Q9VPR0
LP14662p

1

3

High-throughput

0.489

High

1173694

TONSL
Tonsoku-like protein

1

5

High-throughput

0.489

High

1173695

Q9VSH1
GH01354p

1

1

High-throughput

0.489

High

1173696

PUS7
Pseudouridylate synthase 7 homolog

1

1

High-throughput

0.489

High

1173698

CHRB
Protein charybde

1

1

High-throughput

0.489

High

1173699

Q9VUB5
UpSET, isoform A

1

1

High-throughput

0.489

High

1173700

Q9VUQ9
non-specific serine/threonine protein kinase

1

1

High-throughput

0.489

High

1173701

Q9VV75
AT02348p

1

1

High-throughput

0.489

High

1173705

Q9VVP2
MIP25823p1

1

1

High-throughput

0.489

High

1173709

Q9VXV3
Shattered

1

1

High-throughput

0.489

High

1173710

Q9VXW2
Probable ATP-dependent RNA helicase DDX46

1

3

High-throughput

0.489

High

1173711

Q9VZ30
C2H2-type domain-containing protein

1

5

High-throughput

0.489

High

1173713

Q9VZF5
Kinesin-like protein

1

2

High-throughput

0.489

High

1173716

INT1
Integrator complex subunit 1

1

1

High-throughput

0.489

High

1173717

Q9W1R3
Golgin-245

1

7

High-throughput

0.489

High

1173718

Q9W246
Uncharacterized protein

1

1

High-throughput

0.489

High

1173720

PANX
Protein panoramix

1

1

High-throughput

0.489

High

1173721

CAPZA
F-actin-capping protein subunit alpha

1

1

High-throughput

0.489

High

1173723

Q9W3W6
Small ovary, isoform A

1

4

High-throughput

0.489

High

1173725

RTEL1
Regulator of telomere elongation helicase 1 homolog

1

1

High-throughput

0.489

High

1173729

RHGF
Rho GTPase-activating protein Graf

1

1

High-throughput

0.489

High

120589

M9PDM4
Phosphatidylinositol 4-kinase alpha

1

8

High-throughput

0.479

High

121951

M9PH36
Zinc finger DHHC-type containing 8, isoform E

1

3

High-throughput

0.479

High

122130

M9PHQ1
ATP binding cassette subfamily A member 3, isoform D

1

4

High-throughput

0.479

High

122138

M9PHS6
Down syndrome cell adhesion molecule 4, isoform I

1

4

High-throughput

0.479

High

476933

NDKA
Nucleoside diphosphate kinase

1

1

High-throughput

0.479

High

1024290

LAMA
Laminin subunit alpha

1

3

High-throughput

0.479

High

1173657

Q9V483
Unc-13, isoform C

1

4

High-throughput

0.479

High

1173707

RG190
Rho GTPase-activating protein 190

1

0

Small-scale

0.458

High

756777

FAS2
Fasciclin-2

1

4

High-throughput

0.445

High

1173642

Q8IM86
Unc-13, isoform B

1

3

High-throughput

0.445

High

1173643

Q8IM87
Unc-13, isoform A

1

3

High-throughput

0.445

High

1173693

Q9VRG4
ATP binding cassette subfamily A member 3, isoform B

1

4

High-throughput

0.445

High

1173722

ZDHC8
Palmitoyltransferase ZDHHC8

1

3

High-throughput

0.445

High

1173726

Q9W4X4
Phosphatidylinositol 4-kinase alpha

1

5

High-throughput

0.445

High

68221

A8DYA3
Toutatis, isoform E

1

2

High-throughput

0.437

High

68235

A8DYB0
Midasin

1

8

High-throughput

0.437

High

68430

A8DYV5
Nuclear receptor coactivator 6, isoform F

1

2

High-throughput

0.437

High

84520

B7YZK8
Thin, isoform C

1

5

High-throughput

0.437

High

95100

E1JHG4
Uncharacterized protein, isoform C

1

2

High-throughput

0.437

High

117713

L0MPX5
Asator, isoform I

1

2

High-throughput

0.437

High

121046

M9PEP8
Muscle-specific protein 300 kDa, isoform M

1

4

High-throughput

0.437

High

121631

M9PFR8
Artemis, isoform B

1

3

High-throughput

0.437

High

1070567

Q0KHR5
Rho GTPase activating protein at 15B, isoform B

1

4

High-throughput

0.437

High

1070866

Q0KI05
Uncharacterized protein

1

8

High-throughput

0.437

High

1168988

Q1LZ38
Dynein, axonemal, heavy chain 3, isoform E

1

2

High-throughput

0.437

High

1173640

Q7KU78
RNA helicase

1

3

High-throughput

0.437

High

1173666

Q9VC42
Uncharacterized protein, isoform B

1

2

High-throughput

0.437

High

1173667

PUF
Ubiquitin carboxyl-terminal hydrolase puf

1

2

High-throughput

0.437

High

1173728

X2J8Y9
Uncharacterized protein, isoform J

1

2

High-throughput

0.437

High

1173730

X2JEC4
Uncharacterized protein, isoform Y

1

5

High-throughput

0.437

High

68498

A8E6J4
Nucleoside diphosphate kinase

1

1

High-throughput

0.407

High

117879

M9MRD4
Muscle-specific protein 300 kDa, isoform B

1

4

High-throughput

0.407

High

118073

M9MSG3
Muscle-specific protein 300 kDa, isoform E

1

9

High-throughput

0.407

High

118849

M9NFI9
Neurabin-1

1

7

High-throughput

0.407

High

121213

ALDR
Aldo-keto reductase 1B

1

1

High-throughput

0.407

High

1173635

Q7JUV6
GH06739p

1

3

High-throughput

0.407

High

1173644

Q8IMW2
ubiquitinyl hydrolase 1

1

2

High-throughput

0.407

High

1173648

Q8MZI3
RNA helicase

1

3

High-throughput

0.407

High

1173651

Q95TU2
LD23187p

1

7

High-throughput

0.407

High

1173659

Q9V4D6
Asator, isoform D

1

2

High-throughput

0.407

High

1173665

Q9VC41
FI03419p

1

2

High-throughput

0.407

High

1173687

Q9VMS2
Nuclear receptor coactivator 6, isoform C

1

2

High-throughput

0.407

High

1173697

Q9VTH2
FI22313p1

1

2

High-throughput

0.407

High

1173702

Q9VV82
Artemis, isoform A

1

3

High-throughput

0.407

High

1173708

Q9VX92
Rho GTPase activating protein at 15B, isoform C

1

5

High-throughput

0.407

High

1173712

Q9VZ77
Dynein, axonemal, heavy chain 3, isoform D

1

9

High-throughput

0.407

High

1173715

Q9W053
Zormin, isoform F

1

5

High-throughput

0.407

High

51976

A1Z6J6
Uncharacterized protein

1

0

High-throughput

0.279

Low

603707

PH4H
Protein henna

1

0

High-throughput

0.279

Low

668108

PPIA
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.279

Low

782857

TNNI
Troponin I

1

0

High-throughput

0.279

Low

831772

GSTS1
Glutathione S-transferase S1

1

0

High-throughput

0.279

Low

1173646

TRR
Histone-lysine N-methyltransferase trr

1

0

High-throughput

0.279

Low

1173650

Q8SZK9
HL04814p

1

0

High-throughput

0.279

Low

1173664

Q9VAY2
Heat shock protein 83

1

0

High-throughput

0.279

Low

1173690

DMAC2
Distal membrane arm assembly component 2

1

0

High-throughput

0.279

Low

1173703

Q9VVA4
Glutamate synthase [NADH]

1

0

High-throughput

0.279

Low

1173645

Q8IMW5
Molting defective, isoform A

1

0

High-throughput

0.249

Low

1173653

MYSN
Myosin heavy chain, non-muscle

1

0

High-throughput

0.249

Low

1173671

Q9VEH1
LD04521p

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025