Protein: AP180
Clathrin coat assembly protein AP180 (91 kDa synaptosomal-associated protein) (Clathrin coat-associated protein AP180) (Phosphoprotein F1-20)

Gene: AP180, SNAP91
Organism: Homo sapiens
Interactions: 52
UniProt ID: O60641

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0005545 - 1-phosphatidylinositol binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005905 - clathrin-coated pit
GO:0008021 - synaptic vesicle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

237886

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

9

High-throughput

0.691

High

118132

HAX1
HCLS1-associated protein X-1

3

1

High-throughput

0.667

High

237877

EPS15
Epidermal growth factor receptor substrate 15

2

10

Small-scale

0.619

High

237869

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

6

High-throughput

0.618

High

237870

TAU
Microtubule-associated protein tau

2

14

High-throughput

0.611

High

237892

DGUOK
Deoxyguanosine kinase, mitochondrial

3

1

High-throughput

0.609

High

237881

GEM
GTP-binding protein GEM

2

1

High-throughput

0.553

High

237900

MIPO1
Mirror-image polydactyly gene 1 protein

2

2

High-throughput

0.553

High

237911

ABI2
Abl interactor 2

2

3

High-throughput

0.553

High

237901

MIPT3
TRAF3-interacting protein 1

2

4

High-throughput

0.539

High

237880

CLH2
Clathrin heavy chain 2

1

8

High-throughput

0.536

High

237890

RABE1
Rab GTPase-binding effector protein 1

1

7

High-throughput

0.536

High

237902

RBCC1
RB1-inducible coiled-coil protein 1

1

9

High-throughput

0.536

High

237866

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

13

High-throughput

0.526

High

237875

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

14

High-throughput

0.526

High

237891

ERBB4
Receptor tyrosine-protein kinase erbB-4

2

14

High-throughput

0.526

High

237893

GLE1
mRNA export factor GLE1

1

5

High-throughput

0.515

High

237896

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.515

High

237914

RABX5
Rab5 GDP/GTP exchange factor

1

0

High-throughput

0.513

High

237874

VINC
Vinculin

1

1

High-throughput

0.489

High

237876

BRCA1
Breast cancer type 1 susceptibility protein

1

6

High-throughput

0.489

High

237878

PEX5
Peroxisomal targeting signal 1 receptor

1

7

High-throughput

0.489

High

237879

GPM6A
Neuronal membrane glycoprotein M6-a

1

1

High-throughput

0.489

High

237884

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

12

High-throughput

0.489

High

237888

SETB1
Histone-lysine N-methyltransferase SETDB1

1

4

High-throughput

0.489

High

237889

PCM1
Pericentriolar material 1 protein

1

1

High-throughput

0.489

High

237897

MIB1
E3 ubiquitin-protein ligase MIB1

1

5

High-throughput

0.489

High

237899

ANR52
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

1

4

High-throughput

0.489

High

237903

TRI44
Tripartite motif-containing protein 44

1

1

High-throughput

0.489

High

237904

DCAF5
DDB1- and CUL4-associated factor 5

1

8

High-throughput

0.489

High

237905

MELPH
Melanophilin

1

2

High-throughput

0.489

High

237909

SENP3
Sentrin-specific protease 3

1

1

High-throughput

0.489

High

237912

MS18A
Protein Mis18-alpha

1

1

High-throughput

0.489

High

237883

CLH1
Clathrin heavy chain 1

1

8

Small-scale

0.479

High

237885

AP1B1
AP-1 complex subunit beta-1

1

10

Small-scale

0.479

High

237865

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

237908

DNJC5
DnaJ homolog subfamily C member 5

1

5

High-throughput

0.457

High

237871

FGFR1
Fibroblast growth factor receptor 1

1

7

High-throughput

0.437

High

237872

LYL1
Protein lyl-1

1

4

High-throughput

0.437

High

237882

ARF6
ADP-ribosylation factor 6

1

1

Small-scale

0.437

High

237895

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.437

High

237898

SMC5
Structural maintenance of chromosomes protein 5

1

5

High-throughput

0.437

High

237867

JUN
Transcription factor Jun

1

7

High-throughput

0.407

High

237887

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

5

High-throughput

0.407

High

237910

KTU
Protein kintoun

3

0

High-throughput

0.347

High

237913

NUFP1
FMR1-interacting protein NUFIP1

3

0

High-throughput

0.347

High

237894

BOREA
Borealin

2

0

High-throughput

0.318

High

237864

GEMI
Geminin

1

0

High-throughput

0.279

Low

237868

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

1

0

High-throughput

0.279

Low

237906

NTM1A
N-terminal Xaa-Pro-Lys N-methyltransferase 1

1

0

High-throughput

0.279

Low

237907

FANCJ
Fanconi anemia group J protein

1

0

High-throughput

0.279

Low

237873

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024