Protein: UBP30
Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.4.19.12) (Deubiquitinating enzyme 30) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Ub-specific protease 30)

Gene: UBP30, USP30
Organism: Homo sapiens
Interactions: 105
UniProt ID: Q70CQ3

Gene Ontology (top 5):
GO:0000422 - autophagy of mitochondrion
GO:0000425 - pexophagy
GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

475953

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

5

20

Small-scale

0.919

High

475073

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

20

Small-scale

0.734

High

1072767

TOM20
Mitochondrial import receptor subunit TOM20 homolog

4

1

Small-scale

0.676

High

1063731

EXOS7
Exosome complex component RRP42

3

6

High-throughput

0.667

High

1074152

SF3A1
Splicing factor 3A subunit 1

1

6

High-throughput

0.665

High

227852

PRKN
E3 ubiquitin-protein ligase parkin

1

20

Small-scale

0.647

High

1173940

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

2

1

High-throughput

0.628

High

362536

C1QB
Complement C1q subcomponent subunit B

3

3

High-throughput

0.609

High

1173909

P2RX5
P2X purinoceptor 5

2

0

High-throughput

0.602

High

325246

AIFM1
Apoptosis-inducing factor 1, mitochondrial

2

2

High-throughput

0.584

High

180725

PA2GX
Group 10 secretory phospholipase A2

2

6

High-throughput

0.574

High

545131

PVR
Poliovirus receptor

2

3

High-throughput

0.574

High

674800

GRPR
Gastrin-releasing peptide receptor

2

1

High-throughput

0.574

High

1162219

LRFN4
Leucine-rich repeat and fibronectin type-III domain-containing protein 4

2

5

High-throughput

0.574

High

1173928

PACC1
Proton-activated chloride channel

2

1

High-throughput

0.574

High

1173944

PCDGD
Protocadherin gamma-B1

2

1

High-throughput

0.574

High

369874

ESR1
Estrogen receptor

2

19

High-throughput

0.571

High

1173932

TOM22
Mitochondrial import receptor subunit TOM22 homolog

2

0

Small-scale

0.559

High

1173936

MARH5
E3 ubiquitin-protein ligase MARCHF5

2

0

Small-scale

0.559

High

1156102

RHBD2
Rhomboid domain-containing protein 2

2

1

High-throughput

0.553

High

795982

MAGA8
Melanoma-associated antigen 8

1

2

High-throughput

0.536

High

1173898

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

257485

CREST
Calcium-responsive transactivator

1

1

High-throughput

0.515

High

1173921

CLPB
Mitochondrial disaggregase

1

2

High-throughput

0.515

High

868566

ATX1
Ataxin-1

1

3

High-throughput

0.515

High

283651

JTB
Protein JTB

1

0

High-throughput

0.513

High

224625

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

0

High-throughput

0.493

High

1173915

QKI
KH domain-containing RNA-binding protein QKI

1

0

High-throughput

0.493

High

179208

COPT1
High affinity copper uptake protein 1

1

1

High-throughput

0.489

High

362480

C1QA
Complement C1q subcomponent subunit A

1

3

High-throughput

0.489

High

362591

C1QC
Complement C1q subcomponent subunit C

1

3

High-throughput

0.489

High

895661

CXCR4
C-X-C chemokine receptor type 4

1

2

High-throughput

0.489

High

1078246

EFNB3
Ephrin-B3

1

1

High-throughput

0.489

High

1134222

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

6

High-throughput

0.489

High

1173900

IFT20
Intraflagellar transport protein 20 homolog

1

1

High-throughput

0.489

High

1173904

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

8

High-throughput

0.489

High

1173905

CLC2B
C-type lectin domain family 2 member B

1

1

High-throughput

0.489

High

1173943

PCDBB
Protocadherin beta-11

1

1

High-throughput

0.489

High

867342

DPOG1
DNA polymerase subunit gamma-1

1

0

Small-scale

0.480

High

203973

HTRA2
Serine protease HTRA2, mitochondrial

1

1

High-throughput

0.479

High

231115

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

1

High-throughput

0.479

High

264583

MTX2
Metaxin-2

1

2

High-throughput

0.479

High

297070

TOM70
Mitochondrial import receptor subunit TOM70

1

4

Small-scale

0.479

High

330689

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

5

Small-scale

0.479

High

347133

MYC
Myc proto-oncogene protein

1

11

Small-scale

0.479

High

573759

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

3

High-throughput

0.479

High

626176

APC
Adenomatous polyposis coli protein

1

12

Small-scale

0.479

High

717175

CTNB1
Catenin beta-1

1

13

Small-scale

0.479

High

992011

BAX
Apoptosis regulator BAX

1

2

Small-scale

0.479

High

1041880

CUL3
Cullin-3

1

10

High-throughput

0.479

High

1053036

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

2

High-throughput

0.479

High

1101130

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

1128165

SYAM
Alanine--tRNA ligase, mitochondrial

1

1

High-throughput

0.479

High

1173897

MAVS
Mitochondrial antiviral-signaling protein

1

12

High-throughput

0.479

High

1173899

MIRO2
Mitochondrial Rho GTPase 2

1

9

High-throughput

0.479

High

1173901

CCAR2
Cell cycle and apoptosis regulator protein 2

1

2

Small-scale

0.479

High

1173902

PLD6
Mitochondrial cardiolipin hydrolase

1

1

High-throughput

0.479

High

1173903

MPND
MPN domain-containing protein

1

2

High-throughput

0.479

High

1173906

AKAP1
A-kinase anchor protein 1, mitochondrial

1

2

High-throughput

0.479

High

1173907

ESR2
Estrogen receptor beta

1

17

High-throughput

0.479

High

1173913

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.479

High

1173914

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

2

Small-scale

0.479

High

1173918

RMD3
Regulator of microtubule dynamics protein 3

1

1

High-throughput

0.479

High

1173919

PHB2
Prohibitin-2

1

3

High-throughput

0.479

High

1173922

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

3

High-throughput

0.479

High

1173925

MTG2
Mitochondrial ribosome-associated GTPase 2

1

4

High-throughput

0.479

High

1173929

SFXN1
Sideroflexin-1

1

1

High-throughput

0.479

High

1173933

DDX28
Probable ATP-dependent RNA helicase DDX28

1

19

High-throughput

0.479

High

1173934

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

5

High-throughput

0.479

High

1173938

MTCH1
Mitochondrial carrier homolog 1

1

6

High-throughput

0.479

High

1173945

MTCH2
Mitochondrial carrier homolog 2

1

6

High-throughput

0.479

High

118346

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.458

High

157597

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.458

High

881632

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

949127

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.458

High

1074607

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

1135076

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.458

High

1173910

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.458

High

1173912

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.458

High

1173917

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

0

High-throughput

0.458

High

1173931

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1173941

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

1173942

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.458

High

609374

FGFR3
Fibroblast growth factor receptor 3

1

14

High-throughput

0.437

High

844584

RAB5C
Ras-related protein Rab-5C

1

5

High-throughput

0.437

High

1173916

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.437

High

1173923

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

1

High-throughput

0.437

High

1173926

PKHA4
Pleckstrin homology domain-containing family A member 4

1

16

High-throughput

0.437

High

1173946

W4VSR2
MPN domain containing

1

2

High-throughput

0.437

High

1173927

SG196
Protein O-mannose kinase

3

0

High-throughput

0.347

High

1119835

RFTN2
Raftlin-2

2

0

High-throughput

0.328

High

1173908

EXT2
Exostosin-2

2

0

High-throughput

0.328

High

1173937

SCN3B
Sodium channel regulatory subunit beta-3

2

0

High-throughput

0.328

High

217093

NKG2F
NKG2-F type II integral membrane protein

1

0

High-throughput

0.279

Low

296807

NOL4
Nucleolar protein 4

1

0

High-throughput

0.279

Low

516066

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

0

High-throughput

0.279

Low

1120511

MPPE1
Metallophosphoesterase 1

1

0

High-throughput

0.279

Low

1165271

C16L2
CD164 sialomucin-like 2 protein

1

0

High-throughput

0.279

Low

1173924

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.279

Low

1173939

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

352152

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

1173911

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.249

Low

1173920

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.249

Low

1173930

PLRKT
Plasminogen receptor

1

0

High-throughput

0.249

Low

1173935

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024