Protein: FAT
Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]

Gene: FAT, ft
Organism: Drosophila melanogaster
Interactions: 98
UniProt ID: P33450

Gene Ontology (top 5):
GO:0001736 - establishment of planar polarity
GO:0001737 - establishment of imaginal disc-derived wing hair orientation
GO:0005509 - calcium ion binding
GO:0005739 - mitochondrion
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

753707

DS
Protein dachsous

2

20

Small-scale

0.754

High

303770

DCO
Discs overgrown protein kinase

3

1

Small-scale

0.640

High

613918

SGG
Protein kinase shaggy

2

2

High-throughput

0.628

High

753693

FAT
Cadherin-related tumor suppressor

1

17

Small-scale

0.618

High

753750

LIX1
Protein limb expression 1 homolog

2

3

Small-scale

0.600

High

753700

FOJO
Extracellular serine/threonine protein kinase four-jointed

2

1

Small-scale

0.595

High

57331

DLISH
SH3 domain-containing protein Dlish

2

6

Small-scale

0.584

High

753721

Q8IQA6
Grunge, isoform A

2

1

Small-scale

0.570

High

753717

Q86BH2
Grunge, isoform C

2

1

Small-scale

0.566

High

753760

Q9VX36
NADH dehydrogenase

1

0

Small-scale

0.549

High

753708

SEM1A
Semaphorin-1A

1

5

High-throughput

0.536

High

753745

Q9VFF0
Mitochondrial-processing peptidase subunit beta

1

1

Small-scale

0.508

High

114346

H0RNC4
ATPase protein 9

1

1

Small-scale

0.504

High

753710

Q6NN09
ATPase protein 9

1

1

Small-scale

0.504

High

753742

PERC
Chorion peroxidase

1

0

Small-scale

0.494

High

753696

MOEH
Moesin/ezrin/radixin homolog 1

1

7

High-throughput

0.481

High

263668

O61604
Fimbrin

1

7

High-throughput

0.479

High

693524

DYN
Dynamin

1

1

High-throughput

0.479

High

753694

PNUT
Protein peanut

1

1

High-throughput

0.479

High

753701

HEM
Membrane-associated protein Hem

1

1

High-throughput

0.479

High

753702

AP2A
AP-2 complex subunit alpha

1

2

High-throughput

0.479

High

753706

Q24253
AP complex subunit beta

1

2

High-throughput

0.479

High

753714

TERA
Transitional endoplasmic reticulum ATPase TER94

1

3

High-throughput

0.479

High

753720

Q8IPE8
Trifunctional enzyme subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

753727

ENA
Protein enabled

1

2

High-throughput

0.479

High

753737

EPB41
Protein 4.1 homolog

1

5

High-throughput

0.479

High

753741

Q9VDF4
Cortactin, isoform A

1

2

High-throughput

0.479

High

753767

Q9W1H8
acetyl-CoA C-acyltransferase

1

2

High-throughput

0.479

High

753771

Q9W4N8
LD30122p

1

1

High-throughput

0.479

High

753726

Q8SXX1
Phosphatidylinositol 5-phosphate 4-kinase, isoform A

1

0

High-throughput

0.458

High

753728

MOB1
MOB kinase activator-like 1

1

0

High-throughput

0.458

High

753743

Q9VF10
F-box and leucine-rich repeat protein 7

1

0

Small-scale

0.458

High

753698

KARG
Arginine kinase 1

1

1

Small-scale

0.457

High

753719

Q8IMX4
FI04408p

1

1

Small-scale

0.457

High

753704

Q0E8S4
Semaphorin-1A

1

5

High-throughput

0.442

High

99323

YMEL1
ATP-dependent zinc metalloprotease YME1L

1

0

Small-scale

0.438

High

753725

Q8SX23
RE67967p

1

0

Small-scale

0.438

High

263472

O61380
Eukaryotic translation initiation factor 4G1, isoform A

1

2

High-throughput

0.437

High

357469

INO1
Inositol-3-phosphate synthase

1

1

High-throughput

0.437

High

459993

ALF
Fructose-bisphosphate aldolase

1

1

High-throughput

0.437

High

753695

SUV39
Histone-lysine N-methyltransferase Su(var)3-9

1

2

High-throughput

0.437

High

753699

SEPT2
Septin-2

1

1

High-throughput

0.437

High

753709

Q494K2
Chromosome transmission fidelity 4

1

6

High-throughput

0.437

High

753712

NUP50
Nuclear pore complex protein Nup50

1

1

High-throughput

0.437

High

753713

Q7KLW9
Pre-mRNA-processing factor 19

1

2

High-throughput

0.437

High

753715

Q7KN75
Dodeca-satellite-binding protein 1, isoform A

1

3

High-throughput

0.437

High

753716

Q7KV89
Mitogen-activated protein kinase kinase kinase kinase

1

2

High-throughput

0.437

High

753718

LASP1
LIM and SH3 domain protein Lasp

1

1

High-throughput

0.437

High

753730

HRS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

2

High-throughput

0.437

High

753738

Q9VAJ2
Mitotic checkpoint protein BUB3

1

2

High-throughput

0.437

High

54740

A1Z8W8
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

1

Small-scale

0.417

High

58368

A1ZBM2
Tubulin-binding cofactor B

1

1

Small-scale

0.417

High

559792

EF2
Eukaryotic translation elongation factor 2

1

1

Small-scale

0.417

High

583659

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

2

Small-scale

0.417

High

633970

TRX
Histone-lysine N-methyltransferase trithorax

1

1

Small-scale

0.417

High

661917

PP2A
Serine/threonine-protein phosphatase PP2A

1

1

Small-scale

0.417

High

753703

Q0E8N3
No long nerve cord, isoform C

1

7

Small-scale

0.417

High

753705

Q1RKS2
IP06825p

1

2

Small-scale

0.417

High

753722

RS8
Small ribosomal subunit protein eS8

1

1

Small-scale

0.417

High

753729

Q95TN8
Serine/threonine-protein kinase greatwall

1

2

Small-scale

0.417

High

753739

Q9VBE0
TweedleB

1

2

Small-scale

0.417

High

753740

Q9VBE2
RE40518p

1

2

Small-scale

0.417

High

753746

Q9VGR1
GRIP and coiled-coil domain containing 88 kDa

1

5

Small-scale

0.417

High

753752

Q9VMZ5
LD19715p

1

2

Small-scale

0.417

High

753757

Q9VUC7
Peroxisomal ATPase PEX1

1

3

Small-scale

0.417

High

753758

MIB
E3 ubiquitin-protein ligase mind-bomb

1

2

Small-scale

0.417

High

753766

NU301
Nucleosome-remodeling factor subunit NURF301

1

3

Small-scale

0.417

High

753768

Q9W205
Jitterbug, isoform F

1

7

Small-scale

0.417

High

53033

A1Z7J7
Protein transport protein Sec31A

1

0

High-throughput

0.249

Low

57747

A1ZB77
Uncharacterized protein, isoform J

1

0

High-throughput

0.249

Low

753697

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

0

High-throughput

0.249

Low

753723

CDV3
Protein CDV3 homolog

1

0

High-throughput

0.249

Low

753731

LAR4
La-related protein Larp4B

1

0

High-throughput

0.249

Low

753733

SEC13
Protein SEC13 homolog

1

0

High-throughput

0.249

Low

753747

TEBPH
Cytosolic Prostaglandin E synthase

1

0

High-throughput

0.249

Low

753749

RAGP1
Ran GTPase-activating protein

1

0

High-throughput

0.249

Low

753754

Q9VPX6
Adenylyl cyclase-associated protein

1

0

High-throughput

0.249

Low

753770

Q9W3Y3
Calcyclin-binding protein

1

0

High-throughput

0.249

Low

753711

Q7JZW2
40S ribosomal protein S15

1

0

Small-scale

0.238

Low

753724

GALT9
Putative polypeptide N-acetylgalactosaminyltransferase 9

1

0

Small-scale

0.238

Low

753732

Q9V3C6
EG:BACR42I17.10 protein

1

0

Small-scale

0.238

Low

753734

Q9V3U6
26-29kD-proteinase

1

0

Small-scale

0.238

Low

753735

Q9V4C1
Uncharacterized protein, isoform E

1

0

Small-scale

0.238

Low

753736

SUB
Kinesin-like protein subito

1

0

Small-scale

0.238

Low

753744

Q9VF34
Fibrinogen C-terminal domain-containing protein

1

0

Small-scale

0.238

Low

753748

Q9VID9
Uncharacterized protein, isoform B

1

0

Small-scale

0.238

Low

753751

Q9VLX9
Uncharacterized protein, isoform B

1

0

Small-scale

0.238

Low

753753

Q9VP35
alkaline phosphatase

1

0

Small-scale

0.238

Low

753755

Q9VU37
Protein-S-isoprenylcysteine O-methyltransferase

1

0

Small-scale

0.238

Low

753756

Q9VU59
GEO07864p1

1

0

Small-scale

0.238

Low

753759

Q9VVQ2
RE03769p

1

0

Small-scale

0.238

Low

753761

NEMP
Nuclear envelope integral membrane protein

1

0

Small-scale

0.238

Low

753762

Q9VXK9
Centrosomal protein 164, isoform A

1

0

Small-scale

0.238

Low

753763

Q9VYX8
LD04844p

1

0

Small-scale

0.238

Low

753764

Q9VZJ2
GH27759p

1

0

Small-scale

0.238

Low

753765

Q9W0H1
Uncharacterized protein, isoform A

1

0

Small-scale

0.238

Low

753769

RL17
Large ribosomal subunit protein uL22

1

0

Small-scale

0.238

Low


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Last updated: 11Aug2025