Protein: MIA40
Mitochondrial intermembrane space import and assembly protein 40 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4)

Gene: MIA40, CHCHD4
Organism: Homo sapiens
Interactions: 113
UniProt ID: Q8N4Q1

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005758 - mitochondrial intermembrane space
GO:0015035 - protein-disulfide reductase activity
GO:0018171 - peptidyl-cysteine oxidation
GO:0022417 - protein maturation by protein folding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

325276

AIFM1
Apoptosis-inducing factor 1, mitochondrial

4

0

High-throughput

0.658

High

1233795

CHCH5
Coiled-coil-helix-coiled-coil-helix domain-containing protein 5

1

0

High-throughput

0.656

High

540747

CX6B1
Cytochrome c oxidase subunit 6B1

2

2

High-throughput

0.611

High

878603

ALR
FAD-linked sulfhydryl oxidase ALR

2

1

Small-scale

0.601

High

905480

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

2

2

Small-scale

0.601

High

473406

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

2

0

High-throughput

0.585

High

1233786

COA7
Cytochrome c oxidase assembly factor 7

2

0

Small-scale

0.576

High

1233803

SFXN1
Sideroflexin-1

2

0

High-throughput

0.559

High

1048008

COX17
Cytochrome c oxidase copper chaperone

1

0

Small-scale

0.545

High

849789

SUOX
Sulfite oxidase, mitochondrial

1

1

High-throughput

0.536

High

1223651

MICU2
Calcium uptake protein 2, mitochondrial

1

2

High-throughput

0.536

High

1233793

MICU1
Calcium uptake protein 1, mitochondrial

1

2

Small-scale

0.536

High

1233800

ADT4
ADP/ATP translocase 4

1

2

High-throughput

0.536

High

1233816

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

2

High-throughput

0.536

High

217580

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.513

High

231124

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

0

High-throughput

0.513

High

311169

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

1

0

High-throughput

0.513

High

433070

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.513

High

495569

THIO
Thioredoxin

1

0

High-throughput

0.513

High

568467

NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

1

0

High-throughput

0.513

High

602123

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

0

High-throughput

0.513

High

621211

KTHY
Thymidylate kinase

1

0

High-throughput

0.513

High

678019

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.513

High

1144710

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

0

High-throughput

0.513

High

1157945

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

0

High-throughput

0.513

High

1192554

CTU1
Cytoplasmic tRNA 2-thiolation protein 1

1

0

High-throughput

0.513

High

1203653

COA5
Cytochrome c oxidase assembly factor 5

1

0

High-throughput

0.513

High

1218815

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1233813

EXOG
Nuclease EXOG, mitochondrial

1

0

High-throughput

0.513

High

320545

OXSR1
Serine/threonine-protein kinase OSR1

1

1

High-throughput

0.489

High

967585

CDR2
Cerebellar degeneration-related protein 2

1

1

High-throughput

0.489

High

1203697

CDR2L
Cerebellar degeneration-related protein 2-like

1

1

High-throughput

0.489

High

1233801

WNK1
Serine/threonine-protein kinase WNK1

1

1

High-throughput

0.489

High

1233811

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

1

High-throughput

0.489

High

1151413

CPIN1
Anamorsin

1

0

Small-scale

0.480

High

274578

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

1

High-throughput

0.479

High

1233782

CHC10
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial

1

2

High-throughput

0.479

High

876011

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

High-throughput

0.460

High

276852

SCO1
Protein SCO1 homolog, mitochondrial

1

0

High-throughput

0.458

High

488757

ARAF
Serine/threonine-protein kinase A-Raf

1

0

High-throughput

0.458

High

949134

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.458

High

1233779

ABHDB
sn-1-specific diacylglycerol lipase ABHD11

1

0

High-throughput

0.458

High

1233784

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1233790

TMX3
Protein disulfide-isomerase TMX3

1

0

High-throughput

0.458

High

1233791

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.458

High

1233792

PHB2
Prohibitin-2

1

0

High-throughput

0.458

High

1233796

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.458

High

1233798

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

0

High-throughput

0.458

High

1233804

SUCHY
Succinate--hydroxymethylglutarate CoA-transferase

1

0

High-throughput

0.458

High

1233806

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.458

High

224629

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

3

Small-scale

0.445

High

1233815

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

3

Small-scale

0.445

High

776155

ARL1
ADP-ribosylation factor-like protein 1

1

1

High-throughput

0.437

High

1168891

M3K15
Mitogen-activated protein kinase kinase kinase 15

1

1

High-throughput

0.437

High

118365

HAX1
HCLS1-associated protein X-1

1

0

Small-scale

0.426

High

873051

KAD2
Adenylate kinase 2, mitochondrial

1

0

Small-scale

0.426

High

873786

AIF1
Allograft inflammatory factor 1

1

0

Small-scale

0.426

High

1118916

MIX23
Protein MIX23

1

0

Small-scale

0.426

High

1233788

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

0

Small-scale

0.426

High

1127983

TOIP1
Torsin-1A-interacting protein 1

2

0

High-throughput

0.328

High

214726

SSNA1
Microtubule nucleation factor SSNA1

2

0

Small-scale

0.313

High

1233785

CC127
Coiled-coil domain-containing protein 127

2

0

Small-scale

0.313

High

1233808

MED29
Mediator of RNA polymerase II transcription subunit 29

2

0

Small-scale

0.313

High

1031686

GRB10
Growth factor receptor-bound protein 10

2

0

High-throughput

0.298

High

213731

ENSA
Alpha-endosulfine

1

0

High-throughput

0.279

Low

218034

PEX1
Peroxisomal ATPase PEX1

1

0

High-throughput

0.279

Low

270427

KS6A5
Ribosomal protein S6 kinase alpha-5

1

0

High-throughput

0.279

Low

807440

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.279

Low

851592

NEK4
Serine/threonine-protein kinase Nek4

1

0

High-throughput

0.279

Low

924350

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

0

High-throughput

0.279

Low

940644

F193A
Protein FAM193A

1

0

High-throughput

0.279

Low

1047773

CKAP5
Cytoskeleton-associated protein 5

1

0

High-throughput

0.279

Low

1079882

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

0

High-throughput

0.279

Low

1081098

CCDC6
Coiled-coil domain-containing protein 6

1

0

High-throughput

0.279

Low

1116835

GXLT1
Glucoside xylosyltransferase 1

1

0

High-throughput

0.279

Low

1166595

CREL2
Protein disulfide isomerase CRELD2

1

0

High-throughput

0.279

Low

1186072

MICA3
[F-actin]-monooxygenase MICAL3

1

0

High-throughput

0.279

Low

1202990

LIPB1
Liprin-beta-1

1

0

High-throughput

0.279

Low

1224044

TRM2A
tRNA

1

0

High-throughput

0.279

Low

1224169

DCP1B
mRNA-decapping enzyme 1B

1

0

High-throughput

0.279

Low

1233778

NKAP
NF-kappa-B-activating protein

1

0

High-throughput

0.279

Low

1233780

ZNRF2
E3 ubiquitin-protein ligase ZNRF2

1

0

High-throughput

0.279

Low

1233781

THAP4
Peroxynitrite isomerase THAP4

1

0

High-throughput

0.279

Low

1233783

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.279

Low

1233787

ZBT10
Zinc finger and BTB domain-containing protein 10

1

0

High-throughput

0.279

Low

1233789

VPS39
Vam6/Vps39-like protein

1

0

High-throughput

0.279

Low

1233794

KLDC3
Kelch domain-containing protein 3

1

0

High-throughput

0.279

Low

1233799

Z518B
Zinc finger protein 518B

1

0

High-throughput

0.279

Low

1233802

WDR54
WD repeat-containing protein 54

1

0

High-throughput

0.279

Low

1233805

DLRB1
Dynein light chain roadblock-type 1

1

0

High-throughput

0.279

Low

1233807

SLTM
SAFB-like transcription modulator

1

0

High-throughput

0.279

Low

1233809

MOCS1
Molybdenum cofactor biosynthesis protein 1

1

0

High-throughput

0.279

Low

1233810

ZN581
Zinc finger protein 581

1

0

High-throughput

0.279

Low

1233812

ZBT21
Zinc finger and BTB domain-containing protein 21

1

0

High-throughput

0.279

Low

1233814

DDX52
Probable ATP-dependent RNA helicase DDX52

1

0

High-throughput

0.279

Low

1233817

CMTA1
Calmodulin-binding transcription activator 1

1

0

High-throughput

0.279

Low

601947

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

0

High-throughput

0.261

Low

1233797

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.261

Low

129797

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.249

Low

347321

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

418455

NPM
Nucleophosmin

1

0

High-throughput

0.249

Low

795192

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.249

Low

845604

RAB9A
Ras-related protein Rab-9A

1

0

High-throughput

0.249

Low

896145

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.249

Low

908813

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

985187

DUS2
Dual specificity protein phosphatase 2

1

0

High-throughput

0.249

Low

1028327

NDK3
Nucleoside diphosphate kinase 3

1

0

High-throughput

0.249

Low

1138618

OTUD1
OTU domain-containing protein 1

1

0

Small-scale

0.249

Low

330333

NDUBA
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

1

0

Small-scale

0.232

Low

930090

ACTH
Actin, gamma-enteric smooth muscle

1

0

Small-scale

0.232

Low

973777

AKA12
A-kinase anchor protein 12

1

0

Small-scale

0.232

Low

1017170

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.232

Low

1218553

MA7D3
MAP7 domain-containing protein 3

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024