Protein: FANCJ
Fanconi anemia group J protein (EC 3.6.4.12) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1)

Gene: FANCJ, BRIP1
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q9BX63

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0003677 - DNA binding
GO:0003678 - DNA helicase activity
GO:0003682 - chromatin binding
GO:0003724 - RNA helicase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

867638

BLM
RecQ-like DNA helicase BLM

2

0

Small-scale

0.801

High

749834

BRCA1
Breast cancer type 1 susceptibility protein

38

3

Small-scale

0.771

High

776387

MLH1
DNA mismatch repair protein Mlh1

13

2

Small-scale

0.761

High

869885

PMS2
Mismatch repair endonuclease PMS2

6

2

Small-scale

0.735

High

1305944

BARD1
BRCA1-associated RING domain protein 1

6

2

Small-scale

0.725

High

1266880

TOPB1
DNA topoisomerase 2-binding protein 1

7

0

Small-scale

0.714

High

1314973

FANCJ
Fanconi anemia group J protein

1

0

Small-scale

0.674

High

1302975

MMS19
MMS19 nucleotide excision repair protein homolog

3

4

Small-scale

0.674

High

310783

VAPB
Vesicle-associated membrane protein-associated protein B/C

3

0

High-throughput

0.638

High

1044695

FHL3
Four and a half LIM domains protein 3

3

0

High-throughput

0.638

High

1233648

CARME
Carnosine N-methyltransferase

3

0

High-throughput

0.638

High

1314977

SG196
Protein O-mannose kinase

3

0

High-throughput

0.638

High

1314974

FACD2
Fanconi anemia group D2 protein

3

0

Small-scale

0.636

High

652151

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

2

Small-scale

0.634

High

132027

VMA5A
von Willebrand factor A domain-containing protein 5A

2

2

High-throughput

0.628

High

260671

AVIL
Advillin

2

2

High-throughput

0.628

High

1152381

CNDH2
Condensin-2 complex subunit H2

2

1

High-throughput

0.628

High

1239472

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

2

1

High-throughput

0.628

High

1314979

DOCK5
Dedicator of cytokinesis protein 5

2

1

High-throughput

0.628

High

869846

PMS1
PMS1 protein homolog 1

2

2

High-throughput

0.611

High

1263107

LIPH
Lipase member H

3

1

High-throughput

0.609

High

124524

TULP2
Tubby-related protein 2

2

0

High-throughput

0.602

High

837080

MRE11
Double-strand break repair protein MRE11

2

0

Small-scale

0.598

High

283010

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

2

5

Small-scale

0.584

High

360368

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

2

High-throughput

0.584

High

935195

H31
Histone H3.1

2

1

Small-scale

0.584

High

1222552

SLX4
Structure-specific endonuclease subunit SLX4

2

2

High-throughput

0.584

High

1314990

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

5

Small-scale

0.561

High

246276

NBN
Nibrin

2

0

Small-scale

0.559

High

274776

RA51D
DNA repair protein RAD51 homolog 4

1

3

High-throughput

0.536

High

515933

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

2

High-throughput

0.536

High

986842

PSME1
Proteasome activator complex subunit 1

1

2

High-throughput

0.536

High

1069492

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

1283578

TRI52
E3 ubiquitin-protein ligase TRIM52

1

1

High-throughput

0.536

High

1314986

NDOR1
NADPH-dependent diflavin oxidoreductase 1

1

1

High-throughput

0.536

High

1314985

HDAC6
Histone deacetylase 6

1

1

High-throughput

0.515

High

796169

MAGA9
Melanoma-associated antigen 9

1

0

High-throughput

0.513

High

1205483

PALB2
Partner and localizer of BRCA2

1

0

Small-scale

0.513

High

1231854

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.513

High

1314975

DRC3
Dynein regulatory complex subunit 3

1

0

High-throughput

0.513

High

177375

HDAC3
Histone deacetylase 3

1

1

Small-scale

0.501

High

1270786

CBP
CREB-binding protein

1

3

Small-scale

0.501

High

1077478

ELAV1
ELAV-like protein 1

1

0

High-throughput

0.493

High

179254

COPT1
High affinity copper uptake protein 1

1

2

High-throughput

0.489

High

296825

NOL4
Nucleolar protein 4

1

1

High-throughput

0.489

High

1290932

I17RA
Interleukin-17 receptor A

1

2

High-throughput

0.489

High

1289416

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

0

Small-scale

0.480

High

131067

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

2

High-throughput

0.479

High

553620

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

721345

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

805557

BRCC3
Lys-63-specific deubiquitinase BRCC36

1

1

Small-scale

0.479

High

826351

CDK8
Cyclin-dependent kinase 8

1

2

High-throughput

0.479

High

952603

H33
Histone H3.3

1

1

High-throughput

0.479

High

980863

TLE3
Transducin-like enhancer protein 3

1

2

High-throughput

0.479

High

1042453

CUL3
Cullin-3

1

3

High-throughput

0.479

High

1198273

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

1

Small-scale

0.479

High

1244468

NUP43
Nucleoporin Nup43

1

1

High-throughput

0.479

High

1246167

COP1
E3 ubiquitin-protein ligase COP1

1

1

High-throughput

0.479

High

1314976

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

556958

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.458

High

652980

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

847888

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.458

High

1027239

CBX3
Chromobox protein homolog 3

1

0

Small-scale

0.458

High

1188814

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1191253

DPOLN
DNA polymerase nu

1

0

Small-scale

0.458

High

1221704

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1272021

RAD50
DNA repair protein RAD50

1

0

Small-scale

0.458

High

1288286

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.458

High

1314978

CIAO3
Cytosolic iron-sulfur assembly component 3

1

0

Small-scale

0.458

High

1314982

ETAA1
Ewing's tumor-associated antigen 1

1

0

Small-scale

0.458

High

1314983

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1314987

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

1314988

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

360661

SPTA1
Spectrin alpha chain, erythrocytic 1

1

1

Small-scale

0.437

High

1165689

ABRX1
BRCA1-A complex subunit Abraxas 1

1

0

Small-scale

0.426

High

1314984

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

3

High-throughput

0.407

High

1314981

GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

3

0

High-throughput

0.347

High

1308585

DHB14
17-beta-hydroxysteroid dehydrogenase 14

3

0

High-throughput

0.346

High

1165345

LYPD4
Ly6/PLAUR domain-containing protein 4

2

0

High-throughput

0.328

High

1314980

CRAC1
Cartilage acidic protein 1

2

0

High-throughput

0.328

High

237907

AP180
Clathrin coat assembly protein AP180

1

0

High-throughput

0.279

Low

971101

OC90
Otoconin-90

1

0

High-throughput

0.279

Low

1314989

CRYL1
Lambda-crystallin homolog

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024