Protein: PTN18
Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase)

Gene: PTN18, PTPN18
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q99952

Gene Ontology (top 5):
GO:0001825 - blastocyst formation
GO:0004725 - protein tyrosine phosphatase activity
GO:0004726 - non-membrane spanning protein tyrosine phosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

338901

EGFR
Epidermal growth factor receptor

3

20

High-throughput

0.843

High

383950

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.761

High

1307332

PPIP2
Proline-serine-threonine phosphatase-interacting protein 2

4

14

High-throughput

0.694

High

924822

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.691

High

207829

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

3

15

Small-scale

0.682

High

1168408

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.625

High

1307324

PTN18
Tyrosine-protein phosphatase non-receptor type 18

1

19

High-throughput

0.618

High

118783

AIP
AH receptor-interacting protein

2

3

High-throughput

0.611

High

1307336

BAG5
BAG family molecular chaperone regulator 5

2

0

High-throughput

0.602

High

684983

STIP1
Stress-induced-phosphoprotein 1

2

4

High-throughput

0.584

High

155854

SH21B
SH2 domain-containing protein 1B

1

20

Small-scale

0.575

High

789088

ABL2
Tyrosine-protein kinase ABL2

1

20

Small-scale

0.575

High

151880

IRS4
Insulin receptor substrate 4

1

7

High-throughput

0.536

High

243573

DNJA2
DnaJ homolog subfamily A member 2

1

2

High-throughput

0.536

High

273963

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.536

High

325347

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

2

High-throughput

0.536

High

504648

HSP7C
Heat shock cognate 71 kDa protein

1

7

High-throughput

0.536

High

636406

DNJB1
DnaJ homolog subfamily B member 1

1

2

High-throughput

0.536

High

1046555

TBB2A
Tubulin beta-2A chain

1

4

High-throughput

0.536

High

1128122

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

1

High-throughput

0.536

High

1300864

PASK
PAS domain-containing serine/threonine-protein kinase

1

9

High-throughput

0.536

High

1305077

DNJC7
DnaJ homolog subfamily C member 7

1

4

High-throughput

0.536

High

1305671

ATX2
Ataxin-2

1

2

High-throughput

0.536

High

1307326

CAB45
45 kDa calcium-binding protein

1

6

High-throughput

0.536

High

1307327

TBB6
Tubulin beta-6 chain

1

4

High-throughput

0.536

High

1307329

TRIM7
E3 ubiquitin-protein ligase TRIM7

1

2

High-throughput

0.536

High

1307334

WRP73
WD repeat-containing protein WRAP73

1

1

High-throughput

0.536

High

1307337

CHIP
E3 ubiquitin-protein ligase CHIP

1

2

High-throughput

0.536

High

1307338

FBW1A
F-box/WD repeat-containing protein 1A

1

3

Small-scale

0.515

High

272449

TIPRL
TIP41-like protein

1

0

High-throughput

0.513

High

323992

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

1022661

AF1Q
Protein AF1q

1

0

High-throughput

0.513

High

1058709

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

High-throughput

0.513

High

637038

ATPA
ATP synthase subunit alpha, mitochondrial

1

2

High-throughput

0.489

High

1307335

STML2
Stomatin-like protein 2, mitochondrial

1

6

High-throughput

0.489

High

500048

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.479

High

575560

EGR1
Early growth response protein 1

1

4

Small-scale

0.479

High

776179

ARL1
ADP-ribosylation factor-like protein 1

1

8

High-throughput

0.479

High

950551

ARF1
ADP-ribosylation factor 1

1

5

High-throughput

0.479

High

1216294

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

1

High-throughput

0.479

High

1307325

LZTS2
Leucine zipper putative tumor suppressor 2

1

8

High-throughput

0.479

High

1307333

SI1L2
Signal-induced proliferation-associated 1-like protein 2

1

3

High-throughput

0.479

High

413108

AGAL
Alpha-galactosidase A

1

0

High-throughput

0.458

High

1281530

CNKR1
Connector enhancer of kinase suppressor of ras 1

1

11

Small-scale

0.457

High

118422

HAX1
HCLS1-associated protein X-1

1

1

High-throughput

0.437

High

153375

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

1

High-throughput

0.437

High

680105

SSR4
Somatostatin receptor type 4

1

10

High-throughput

0.437

High

1220728

MIRO1
Mitochondrial Rho GTPase 1

1

20

High-throughput

0.437

High

1262381

MAIP1
m-AAA protease-interacting protein 1, mitochondrial

1

2

High-throughput

0.437

High

1295307

TMX3
Protein disulfide-isomerase TMX3

1

9

High-throughput

0.437

High

1307331

CPVL
Probable serine carboxypeptidase CPVL

1

1

High-throughput

0.437

High

1307328

SYTM
Threonine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

1307330

TNG6
Transport and Golgi organization protein 6 homolog

1

0

High-throughput

0.279

Low

266791

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.249

Low

431271

CATB
Cathepsin B

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024