Protein: CSN7B
COP9 signalosome complex subunit 7b (SGN7b) (Signalosome subunit 7b) (JAB1-containing signalosome subunit 7b)

Gene: CSN7B, COPS7B
Organism: Homo sapiens
Interactions: 118
UniProt ID: Q9H9Q2

Gene Ontology (top 5):
GO:0000338 - protein deneddylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1272616

CSN5
COP9 signalosome complex subunit 5

15

20

Small-scale

0.984

High

1334410

CSN3
COP9 signalosome complex subunit 3

10

18

Small-scale

0.974

High

1184985

CSN6
COP9 signalosome complex subunit 6

9

20

Small-scale

0.972

High

897312

CSN2
COP9 signalosome complex subunit 2

7

20

Small-scale

0.962

High

1311900

CSN4
COP9 signalosome complex subunit 4

6

9

Small-scale

0.944

High

1305351

CSN8
COP9 signalosome complex subunit 8

5

3

Small-scale

0.925

High

1024222

CSN1
COP9 signalosome complex subunit 1

5

20

Small-scale

0.924

High

1334406

CSN7A
COP9 signalosome complex subunit 7a

2

2

High-throughput

0.811

High

1043232

CUL4A
Cullin-4A

9

12

Small-scale

0.751

High

1042568

CUL3
Cullin-3

7

12

Small-scale

0.744

High

1043598

CUL4B
Cullin-4B

6

12

Small-scale

0.736

High

1041205

CUL1
Cullin-1

4

12

Small-scale

0.691

High

896226

UBC12
NEDD8-conjugating enzyme Ubc12

3

2

High-throughput

0.667

High

1185092

DET1
DET1 homolog

3

1

High-throughput

0.667

High

1255954

DCA11
DDB1- and CUL4-associated factor 11

3

2

High-throughput

0.667

High

1265898

DDB2
DNA damage-binding protein 2

3

4

High-throughput

0.667

High

1274053

CUL5
Cullin-5

3

12

High-throughput

0.667

High

1289619

FBX17
F-box only protein 17

3

3

High-throughput

0.667

High

1082399

DDB1
DNA damage-binding protein 1

3

1

Small-scale

0.656

High

1334399

CSN7B
COP9 signalosome complex subunit 7b

1

2

Small-scale

0.647

High

1030690

NMI
N-myc-interactor

3

0

High-throughput

0.646

High

1028026

ERCC8
DNA excision repair protein ERCC-8

3

3

Small-scale

0.640

High

50460

SYCE3
Synaptonemal complex central element protein 3

2

1

High-throughput

0.628

High

319419

APBB3
Amyloid-beta A4 precursor protein-binding family B member 3

2

1

High-throughput

0.628

High

475195

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

10

High-throughput

0.628

High

566790

JUNB
Transcription factor JunB

2

5

High-throughput

0.628

High

983238

UBE3A
Ubiquitin-protein ligase E3A

2

5

High-throughput

0.628

High

1041468

CUL2
Cullin-2

2

12

High-throughput

0.628

High

1153796

KLH10
Kelch-like protein 10

2

3

High-throughput

0.628

High

1260914

DCAF4
DDB1- and CUL4-associated factor 4

2

2

High-throughput

0.628

High

1300724

SPAG5
Sperm-associated antigen 5

2

1

High-throughput

0.628

High

1327488

BTBD1
BTB/POZ domain-containing protein 1

2

7

High-throughput

0.628

High

1334412

FBX7
F-box only protein 7

2

1

High-throughput

0.628

High

1292390

DCNL1
DCN1-like protein 1

2

1

Small-scale

0.611

High

1334402

FBX6
F-box only protein 6

2

3

High-throughput

0.611

High

603242

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

2

0

High-throughput

0.602

High

974148

DYST
Dystonin

2

0

High-throughput

0.602

High

1224797

ASPM
Abnormal spindle-like microcephaly-associated protein

2

0

High-throughput

0.602

High

1268452

APBP2
Amyloid protein-binding protein 2

2

0

High-throughput

0.602

High

1334409

FEM1B
Protein fem-1 homolog B

2

0

High-throughput

0.602

High

1334413

SKAP
Small kinetochore-associated protein

2

0

High-throughput

0.602

High

1334414

DCAF1
DDB1- and CUL4-associated factor 1

2

4

Small-scale

0.584

High

1125941

BEX5
Protein BEX5

2

0

High-throughput

0.580

High

195758

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

2

3

High-throughput

0.574

High

207747

DENR
Density-regulated protein

2

1

High-throughput

0.574

High

1133264

HECD3
E3 ubiquitin-protein ligase HECTD3

2

7

High-throughput

0.574

High

297678

RHBT1
Rho-related BTB domain-containing protein 1

2

3

High-throughput

0.558

High

452888

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.536

High

1075462

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

2

High-throughput

0.536

High

1079155

STK11
Serine/threonine-protein kinase STK11

1

2

High-throughput

0.536

High

1079606

NEDD8
NEDD8

1

3

High-throughput

0.536

High

1241264

FA98A
Protein FAM98A

1

1

High-throughput

0.536

High

1263349

CSN9
COP9 signalosome complex subunit 9

1

1

High-throughput

0.536

High

1309195

KLDC3
Kelch domain-containing protein 3

1

4

High-throughput

0.536

High

1315078

BTBD2
BTB/POZ domain-containing protein 2

1

7

High-throughput

0.536

High

1334403

AP5S1
AP-5 complex subunit sigma-1

1

1

High-throughput

0.536

High

1334404

ASB6
Ankyrin repeat and SOCS box protein 6

1

1

High-throughput

0.536

High

1334405

RBX2
RING-box protein 2

1

2

High-throughput

0.536

High

388734

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.515

High

64616

MYH7B
Myosin-7B

1

0

High-throughput

0.513

High

146868

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

0

High-throughput

0.513

High

200429

HS12A
Heat shock 70 kDa protein 12A

1

0

High-throughput

0.513

High

317863

CPSF4
Cleavage and polyadenylation specificity factor subunit 4

1

0

High-throughput

0.513

High

350561

RASK
GTPase KRas

1

0

High-throughput

0.513

High

923789

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.513

High

927543

1433Z
14-3-3 protein zeta/delta

1

0

High-throughput

0.513

High

929064

SKP1
S-phase kinase-associated protein 1

1

0

High-throughput

0.513

High

1204271

HOGA1
4-hydroxy-2-oxoglutarate aldolase, mitochondrial

1

0

High-throughput

0.513

High

1204467

FBX11
F-box only protein 11

1

0

High-throughput

0.513

High

1314042

GGACT
Gamma-glutamylaminecyclotransferase

1

0

High-throughput

0.513

High

395800

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

476401

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

10

High-throughput

0.501

High

821414

TCPE
T-complex protein 1 subunit epsilon

1

0

High-throughput

0.493

High

1121803

ANR39
Ankyrin repeat domain-containing protein 39

1

2

High-throughput

0.489

High

1238353

SYT2
Synaptotagmin-2

1

1

High-throughput

0.489

High

1263845

RB40A
Ras-related protein Rab-40A

1

1

High-throughput

0.489

High

295269

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

553746

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

652285

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

721477

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

758339

CDN1A
Cyclin-dependent kinase inhibitor 1

1

1

Small-scale

0.479

High

791992

HD
Huntingtin

1

2

High-throughput

0.479

High

804154

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

1

Small-scale

0.479

High

885059

FBXW4
F-box/WD repeat-containing protein 4

1

5

Small-scale

0.479

High

921434

RBX1
E3 ubiquitin-protein ligase RBX1

1

2

High-throughput

0.479

High

967440

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

1072456

ELOB
Elongin-B

1

1

High-throughput

0.479

High

1139121

TET5C
Terminal nucleotidyltransferase 5C

1

1

High-throughput

0.479

High

1148790

VIR
Protein virilizer homolog

1

3

High-throughput

0.479

High

1171761

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

1200175

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

2

Small-scale

0.479

High

1234381

WDTC1
WD and tetratricopeptide repeats protein 1

1

6

High-throughput

0.479

High

1243946

FBX22
F-box only protein 22

1

2

High-throughput

0.479

High

1246173

COP1
E3 ubiquitin-protein ligase COP1

1

3

High-throughput

0.479

High

1262821

PHIP
PH-interacting protein

1

2

Small-scale

0.479

High

1267166

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

1270701

REQU
Zinc finger protein ubi-d4

1

1

High-throughput

0.479

High

1296808

LLR1
Leucine-rich repeat protein 1

1

1

High-throughput

0.479

High

1302559

CRBN
Protein cereblon

1

1

Small-scale

0.479

High

1314388

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.479

High

1334400

RAB18
Ras-related protein Rab-18

1

1

Small-scale

0.479

High

1334407

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1334411

FBW1A
F-box/WD repeat-containing protein 1A

1

3

Small-scale

0.479

High

1334415

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

3

Small-scale

0.479

High

201441

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.458

High

262585

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

535939

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.458

High

1087104

H2A2C
Histone H2A type 2-C

1

0

High-throughput

0.458

High

1334401

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.458

High

497608

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

975044

CAV1
Caveolin-1

1

1

Small-scale

0.437

High

1159446

FBX42
F-box only protein 42

1

3

High-throughput

0.437

High

1239007

DC4L2
DDB1- and CUL4-associated factor 4-like protein 2

1

2

Small-scale

0.437

High

483721

CT456
Cancer/testis antigen family 45 member A6

1

3

High-throughput

0.407

High

1334408

SUN2
SUN domain-containing protein 2

2

0

High-throughput

0.328

High

1310904

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.279

Low

519828

KCRU
Creatine kinase U-type, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024