Protein: EPM2A
Laforin (EC 3.1.3.-) (EC 3.1.3.16) (EC 3.1.3.48) (Glucan phosphatase) (Glycogen phosphatase) (Lafora PTPase) (LAFPTPase)

Gene: EPM2A
Organism: Homo sapiens
Interactions: 56
UniProt ID: O95278

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0001558 - regulation of cell growth
GO:0004373 - glycogen (starch) synthase activity
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

310373

EPM2A
Laforin

5

0

Small-scale

0.860

High

307572

STBD1
Starch-binding domain-containing protein 1

3

0

High-throughput

0.816

High

310406

NHLC1
E3 ubiquitin-protein ligase NHLRC1

13

1

Small-scale

0.763

High

212337

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

0

Small-scale

0.752

High

310390

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

1

Small-scale

0.740

High

310387

GSK3B
Glycogen synthase kinase-3 beta

1

1

Small-scale

0.713

High

310419

PPR3C
Protein phosphatase 1 regulatory subunit 3C

4

1

Small-scale

0.683

High

310397

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

1

Small-scale

0.647

High

310374

PPR3D
Protein phosphatase 1 regulatory subunit 3D

2

1

Small-scale

0.633

High

310396

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.614

High

310411

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

1

0

Small-scale

0.586

High

310416

NFU1
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

1

0

Small-scale

0.549

High

310379

KPYM
Pyruvate kinase PKM

1

0

Small-scale

0.529

High

310407

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

1

0

High-throughput

0.517

High

310377

PYGB
Glycogen phosphorylase, brain form

1

0

High-throughput

0.513

High

310378

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.493

High

310420

SHLB1
Endophilin-B1

1

0

High-throughput

0.493

High

310380

PRS6A
26S proteasome regulatory subunit 6A

1

1

Small-scale

0.481

High

118661

AIP
AH receptor-interacting protein

1

2

High-throughput

0.479

High

257150

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

1

1

High-throughput

0.479

High

310375

HS74L
Heat shock 70 kDa protein 4L

1

2

High-throughput

0.479

High

310384

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

310385

HSP74
Heat shock 70 kDa protein 4

1

2

High-throughput

0.479

High

310398

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

2

High-throughput

0.479

High

310404

TOM34
Mitochondrial import receptor subunit TOM34

1

4

High-throughput

0.479

High

310417

CHIP
E3 ubiquitin-protein ligase CHIP

1

3

Small-scale

0.479

High

310418

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

1

High-throughput

0.479

High

310400

TDG
G/T mismatch-specific thymine DNA glycosylase

1

0

Small-scale

0.460

High

310401

EI2BA
Translation initiation factor eIF2B subunit alpha

1

0

Small-scale

0.460

High

310413

TOPRS
E3 ubiquitin-protein ligase Topors

1

0

Small-scale

0.460

High

310415

HMGX4
HMG domain-containing protein 4

1

0

Small-scale

0.460

High

256607

CLU
Clustered mitochondria protein homolog

1

0

High-throughput

0.458

High

302745

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

310381

PSB1
Proteasome subunit beta type-1

1

0

High-throughput

0.458

High

310383

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.458

High

310386

TCPE
T-complex protein 1 subunit epsilon

1

0

High-throughput

0.458

High

310388

PPP5
Serine/threonine-protein phosphatase 5

1

0

High-throughput

0.458

High

310389

ATX1
Ataxin-1

1

0

Small-scale

0.458

High

310391

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

High-throughput

0.458

High

310392

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

310393

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

0

Small-scale

0.458

High

310394

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.458

High

310395

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.458

High

310399

SQSTM
Sequestosome-1

1

0

Small-scale

0.458

High

310402

BECN1
Beclin-1

1

0

Small-scale

0.458

High

310403

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.458

High

310405

BRDT
Bromodomain testis-specific protein

1

0

High-throughput

0.458

High

310408

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

0

Small-scale

0.458

High

310409

PREX1
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

1

0

Small-scale

0.458

High

310410

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.458

High

310412

MCMBP
Mini-chromosome maintenance complex-binding protein

1

0

High-throughput

0.458

High

310414

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

297012

TOM70
Mitochondrial import receptor subunit TOM70

1

3

High-throughput

0.437

High

310376

CCKN
Cholecystokinin

1

0

High-throughput

0.268

Low

310382

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

Small-scale

0.251

Low


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Last updated: 15 Jul 2024