Protein: OTP
Homeobox protein orthopedia

Gene: OTP
Organism: Drosophila melanogaster
Interactions: 59
UniProt ID: P56672

Gene Ontology (top 5):
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0030182 - neuron differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

942052

H15
T-box protein H15

2

17

High-throughput

0.767

High

942077

Q9W2P8
Homeobrain

2

20

High-throughput

0.767

High

942065

Q9VMR2
LP04777p

1

17

High-throughput

0.698

High

942041

DICH
SOX domain-containing protein dichaete

3

20

High-throughput

0.661

High

942038

Q0IGU0
IP21556p

1

20

High-throughput

0.637

High

942079

Q9W4B3
Visual system homeobox 2

1

20

High-throughput

0.637

High

929263

GSC
Homeobox protein goosecoid

1

17

High-throughput

0.621

High

942046

Q7KUL4
Intermediate neuroblasts defective

1

20

High-throughput

0.621

High

942081

X2JDS9
Visual system homeobox 2

1

20

High-throughput

0.621

High

467106

CSK2A
Casein kinase II subunit alpha

2

10

High-throughput

0.594

High

662819

DISC
Protein disconnected

2

1

High-throughput

0.594

High

942042

HMG2
High mobility group protein DSP1

2

20

High-throughput

0.594

High

942053

Q961D1
Cyclin-K

2

3

High-throughput

0.594

High

942062

Q9VHX0
LD18233p

2

2

High-throughput

0.594

High

355833

O96620
Intermediate neuroblasts defective protein

1

20

High-throughput

0.590

High

234667

MSTAA
SET domain-containing protein SmydA-8, isoform A

2

0

High-throughput

0.569

High

647278

SUS
Protein suppressor of sable

2

0

High-throughput

0.569

High

942064

Q9VLF2
CCR4-NOT transcription complex subunit 9

2

0

High-throughput

0.569

High

942037

Q058Z8
GEO11848p1

2

1

High-throughput

0.542

High

942050

Q8T3W6
AT27166p

2

1

High-throughput

0.542

High

942056

SEC13
Protein SEC13 homolog

2

6

High-throughput

0.542

High

942058

Q9VGH5
AT27789p

2

4

High-throughput

0.542

High

942066

POLZ2
DNA polymerase zeta subunit 2

2

4

High-throughput

0.542

High

942070

Q9VX24
RE25723p

2

1

High-throughput

0.542

High

942074

Q9W0B3
Vacuolar protein sorting-associated protein VTA1 homolog

2

2

High-throughput

0.542

High

942076

Q9W1V2
Tektin

2

5

High-throughput

0.542

High

942040

HR78
Nuclear hormone receptor HR78

1

20

High-throughput

0.541

High

942043

DRI
Protein dead ringer

1

20

High-throughput

0.541

High

942051

NFKB1
Nuclear factor NF-kappa-B p110 subunit

1

4

High-throughput

0.541

High

942063

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

3

High-throughput

0.541

High

942067

Q9VP57
LD15904p

1

6

High-throughput

0.541

High

120136

M9PCG2
Sox21b, isoform C

1

20

High-throughput

0.494

High

942061

Q9VHB7
LD22928p

1

1

High-throughput

0.481

High

942068

Q9VUD3
GH07353p

1

20

High-throughput

0.481

High

838583

TTKA
Protein tramtrack, alpha isoform

1

12

High-throughput

0.479

High

942039

KU70
ATP-dependent DNA helicase 2 subunit 1

1

6

High-throughput

0.479

High

942044

XPC
DNA repair protein complementing XP-C cells homolog

1

4

High-throughput

0.479

High

942057

Q9VEC5
Importin-13

1

11

High-throughput

0.479

High

942059

BLM
RecQ-like DNA helicase Blm

1

7

High-throughput

0.479

High

942069

Q9VW57
Grasp65

1

6

High-throughput

0.464

High

2598

A0A0B4KGZ0
Methyl-CpG binding domain protein-like, isoform C

1

1

High-throughput

0.457

High

91945

C9QPD3
MIP01511p

1

1

High-throughput

0.451

High

99258

F3YD65
AT13839p

1

1

High-throughput

0.451

High

942047

Q8I942
IP11514p

1

3

High-throughput

0.451

High

942048

Q8INY5
RE08003p1

1

5

High-throughput

0.451

High

942078

Q9W490
FI04818p

1

1

High-throughput

0.451

High

118122

M9MSK1
Uncharacterized protein, isoform B

1

3

High-throughput

0.439

High

942045

Q6IL75
HDC10149

1

1

High-throughput

0.439

High

942049

Q8IP75
FI16829p1

1

1

High-throughput

0.439

High

942080

X2JAJ7
Uncharacterized protein, isoform C

1

1

High-throughput

0.439

High

942082

X2JEH3
Uncharacterized protein, isoform E

1

5

High-throughput

0.439

High

942054

Q9I7M8
ATP-dependent DNA helicase II subunit 2

1

6

High-throughput

0.437

High

942060

RS29
Small ribosomal subunit protein uS14

1

1

High-throughput

0.437

High

896150

MSL3
Protein male-specific lethal-3

2

0

High-throughput

0.310

High

942055

VPS28
Vacuolar protein sorting-associated protein 28 homolog

2

0

High-throughput

0.310

High

942071

Q9VXX0
GH05991p

2

0

High-throughput

0.310

High

942072

Q9VYK9
LP16520p

2

0

High-throughput

0.310

High

942075

5NT3B
7-methylguanosine phosphate-specific 5'-nucleotidase

2

0

High-throughput

0.310

High

942073

Q9VZV8
LD46404p

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025