Protein: NEK8
Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (Nima-related protein kinase 12a)

Gene: NEK8
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q86SG6

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005929 - cilium

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1147960

ANKS6
Ankyrin repeat and SAM domain-containing protein 6

3

6

High-throughput

0.861

High

1173303

ANKS3
Ankyrin repeat and SAM domain-containing protein 3

2

16

High-throughput

0.811

High

1197674

NEK7
Serine/threonine-protein kinase Nek7

2

18

High-throughput

0.811

High

432008

HS90A
Heat shock protein HSP 90-alpha

2

20

High-throughput

0.789

High

438311

HS90B
Heat shock protein HSP 90-beta

2

20

High-throughput

0.789

High

283218

RGS20
Regulator of G-protein signaling 20

2

4

High-throughput

0.783

High

1197671

TRI42
Tripartite motif-containing protein 42

2

20

High-throughput

0.700

High

1197673

OXER1
Oxoeicosanoid receptor 1

2

4

High-throughput

0.700

High

685173

S10AB
Protein S100-A11

1

6

High-throughput

0.691

High

1197680

DNJC7
DnaJ homolog subfamily C member 7

1

12

High-throughput

0.691

High

1197669

TRI69
E3 ubiquitin-protein ligase TRIM69

3

5

High-throughput

0.675

High

1197675

NUDC2
NudC domain-containing protein 2

3

7

High-throughput

0.656

High

1197672

NEK9
Serine/threonine-protein kinase Nek9

1

19

Small-scale

0.647

High

118758

AIP
AH receptor-interacting protein

1

13

High-throughput

0.618

High

337497

ABL1
Tyrosine-protein kinase ABL1

1

9

High-throughput

0.618

High

338638

EGFR
Epidermal growth factor receptor

1

9

High-throughput

0.618

High

412245

FYN
Tyrosine-protein kinase Fyn

1

9

High-throughput

0.618

High

972538

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

16

High-throughput

0.618

High

1082851

CDC37
Hsp90 co-chaperone Cdc37

1

8

High-throughput

0.618

High

1197684

CYBP
Calcyclin-binding protein

2

0

High-throughput

0.585

High

475987

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

11

High-throughput

0.579

High

1123416

H90B4
Putative heat shock protein HSP 90-beta 4

1

20

High-throughput

0.575

High

1197681

METH
Methionine synthase

2

1

High-throughput

0.558

High

1119851

KR132
Keratin-associated protein 13-2

2

2

High-throughput

0.553

High

1166923

ATL4
ADAMTS-like protein 4

2

4

High-throughput

0.553

High

342572

CAH2
Carbonic anhydrase 2

1

1

High-throughput

0.536

High

388551

HSPB1
Heat shock protein beta-1

1

3

High-throughput

0.536

High

539813

IDE
Insulin-degrading enzyme

1

1

High-throughput

0.536

High

551760

DESP
Desmoplakin

1

20

High-throughput

0.536

High

667985

SPB3
Serpin B3

1

4

High-throughput

0.536

High

684164

1433S
14-3-3 protein sigma

1

20

High-throughput

0.536

High

768440

CAPG
Macrophage-capping protein

1

3

High-throughput

0.536

High

1197678

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

1

High-throughput

0.536

High

1197689

CHIP
E3 ubiquitin-protein ligase CHIP

1

7

High-throughput

0.536

High

551191

ITF2
Transcription factor 4

1

2

High-throughput

0.523

High

791715

HD
Huntingtin

1

4

High-throughput

0.515

High

868576

ATX1
Ataxin-1

1

2

High-throughput

0.515

High

207175

TGM5
Protein-glutamine gamma-glutamyltransferase 5

1

0

High-throughput

0.513

High

1197677

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.513

High

820329

SPB4
Serpin B4

1

4

High-throughput

0.489

High

858283

TXTP
Tricarboxylate transport protein, mitochondrial

1

9

High-throughput

0.489

High

1069399

TEBP
Prostaglandin E synthase 3

1

4

High-throughput

0.489

High

1197687

DIC
Mitochondrial dicarboxylate carrier

1

11

High-throughput

0.489

High

1197688

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

7

High-throughput

0.489

High

323428

TTC4
Tetratricopeptide repeat protein 4

1

20

High-throughput

0.479

High

557728

NCK1
SH2/SH3 adapter protein NCK1

1

11

High-throughput

0.479

High

564110

HSP76
Heat shock 70 kDa protein 6

1

7

High-throughput

0.479

High

714003

HS71L
Heat shock 70 kDa protein 1-like

1

6

High-throughput

0.479

High

924672

GRB2
Growth factor receptor-bound protein 2

1

12

High-throughput

0.479

High

1174994

TBA1A
Tubulin alpha-1A chain

1

14

High-throughput

0.479

High

1197670

NUDC3
NudC domain-containing protein 3

1

7

High-throughput

0.479

High

1197682

UN45A
Protein unc-45 homolog A

1

13

High-throughput

0.479

High

1197685

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

1197690

NUDC
Nuclear migration protein nudC

1

7

High-throughput

0.479

High

1197692

PHOCN
MOB-like protein phocein

1

1

High-throughput

0.479

High

1138686

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

0

High-throughput

0.458

High

1197686

UXT
Protein UXT

1

0

High-throughput

0.458

High

814981

LEG7
Galectin-7

1

2

High-throughput

0.445

High

684848

STIP1
Stress-induced-phosphoprotein 1

1

9

High-throughput

0.437

High

772038

VHL
von Hippel-Lindau disease tumor suppressor

1

1

Small-scale

0.437

High

1197679

TTC1
Tetratricopeptide repeat protein 1

1

17

High-throughput

0.437

High

1197683

RPAP3
RNA polymerase II-associated protein 3

1

11

High-throughput

0.437

High

1197691

SGT1
Protein SGT1 homolog

1

7

High-throughput

0.437

High

795174

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.279

Low

879691

ATPK
ATP synthase subunit f, mitochondrial

1

0

High-throughput

0.279

Low

1087663

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

0

High-throughput

0.279

Low

1197676

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024