Protein: WIPI2
WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2)

Gene: WIPI2
Organism: Homo sapiens
Interactions: 91
UniProt ID: Q9Y4P8

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0009267 - cellular response to starvation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1147002

A16L1
Autophagy-related protein 16-1

9

19

Small-scale

0.749

High

1328920

ATG5
Autophagy protein 5

5

4

Small-scale

0.714

High

1332537

BCAS3
BCAS3 microtubule associated cell migration factor

4

10

Small-scale

0.694

High

1309394

DPH2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

3

1

High-throughput

0.667

High

1311624

PHAF1
Phagosome assembly factor 1

3

1

High-throughput

0.667

High

1318086

DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

3

1

High-throughput

0.667

High

1287447

OPTN
Optineurin

2

20

Small-scale

0.634

High

1192285

HUWE1
E3 ubiquitin-protein ligase HUWE1

2

9

Small-scale

0.624

High

1377718

RBGP1
Rab GTPase-activating protein 1

2

2

High-throughput

0.611

High

1219982

BBS7
Bardet-Biedl syndrome 7 protein

2

0

High-throughput

0.602

High

1355954

NAGK
N-acetyl-D-glucosamine kinase

2

0

High-throughput

0.585

High

296781

ATG12
Ubiquitin-like protein ATG12

2

1

Small-scale

0.584

High

875474

TERA
Transitional endoplasmic reticulum ATPase

2

6

Small-scale

0.584

High

1065353

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

1

High-throughput

0.573

High

1082474

DDB1
DNA damage-binding protein 1

1

13

Small-scale

0.561

High

1230078

RPTOR
Regulatory-associated protein of mTOR

1

16

Small-scale

0.561

High

1293782

REEP6
Receptor expression-enhancing protein 6

2

1

High-throughput

0.553

High

1377896

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

2

6

High-throughput

0.553

High

1346266

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.543

High

1185022

CSN6
COP9 signalosome complex subunit 6

1

4

High-throughput

0.541

High

1348404

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.541

High

787614

MTOR
Serine/threonine-protein kinase mTOR

1

14

Small-scale

0.536

High

636456

DNJB1
DnaJ homolog subfamily B member 1

1

11

High-throughput

0.536

High

966797

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

7

High-throughput

0.536

High

1052966

FLNC
Filamin-C

1

18

High-throughput

0.536

High

1140479

BTBD8
BTB/POZ domain-containing protein 8

1

8

High-throughput

0.536

High

1268289

GCN1
Stalled ribosome sensor GCN1

1

20

High-throughput

0.536

High

1272735

CSN5
COP9 signalosome complex subunit 5

1

9

High-throughput

0.536

High

1377060

NUDC
Nuclear migration protein nudC

1

19

High-throughput

0.536

High

358938

CRYAA
Alpha-crystallin A chain

1

3

High-throughput

0.501

High

121883

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

4

Small-scale

0.479

High

149788

COPE
Coatomer subunit epsilon

1

2

Small-scale

0.479

High

182235

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

9

Small-scale

0.479

High

198765

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

1

Small-scale

0.479

High

229166

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.479

High

339192

EGFR
Epidermal growth factor receptor

1

13

High-throughput

0.479

High

475254

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

17

Small-scale

0.479

High

554152

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

607195

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

1

Small-scale

0.479

High

652710

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

721875

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

826954

TCPG
T-complex protein 1 subunit gamma

1

20

Small-scale

0.479

High

835584

GSK3A
Glycogen synthase kinase-3 alpha

1

18

High-throughput

0.479

High

836118

GSK3B
Glycogen synthase kinase-3 beta

1

16

High-throughput

0.479

High

840875

DYN2
Dynamin-2

1

4

High-throughput

0.479

High

864118

AP2S1
AP-2 complex subunit sigma

1

3

Small-scale

0.479

High

907200

PRS8
26S proteasome regulatory subunit 8

1

11

Small-scale

0.479

High

913376

PRS10
26S proteasome regulatory subunit 10B

1

11

Small-scale

0.479

High

914490

RB11A
Ras-related protein Rab-11A

1

4

Small-scale

0.479

High

1020016

ILF3
Interleukin enhancer-binding factor 3

1

12

Small-scale

0.479

High

1024245

CSN1
COP9 signalosome complex subunit 1

1

6

Small-scale

0.479

High

1043328

CUL4A
Cullin-4A

1

20

Small-scale

0.479

High

1043650

CUL4B
Cullin-4B

1

20

Small-scale

0.479

High

1074031

SC23A
Protein transport protein Sec23A

1

3

Small-scale

0.479

High

1083065

CDC37
Hsp90 co-chaperone Cdc37

1

3

Small-scale

0.479

High

1266614

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

3

High-throughput

0.479

High

1286041

ATG2B
Autophagy-related protein 2 homolog B

1

11

Small-scale

0.479

High

1310995

ATGA1
Autophagy-related protein 101

1

1

Small-scale

0.479

High

1313726

LST8
Target of rapamycin complex subunit LST8

1

17

Small-scale

0.479

High

1315731

AP1M1
AP-1 complex subunit mu-1

1

4

Small-scale

0.479

High

1326805

WWTR1
WW domain-containing transcription regulator protein 1

1

10

High-throughput

0.479

High

1191979

TCPR1
Tectonin beta-propeller repeat-containing protein 1

1

0

Small-scale

0.458

High

1251736

NPL4
Nuclear protein localization protein 4 homolog

1

0

Small-scale

0.458

High

118806

AIP
AH receptor-interacting protein

1

18

High-throughput

0.445

High

324695

BAG3
BAG family molecular chaperone regulator 3

1

1

High-throughput

0.445

High

685138

STIP1
Stress-induced-phosphoprotein 1

1

11

High-throughput

0.445

High

858687

PPP5
Serine/threonine-protein phosphatase 5

1

13

High-throughput

0.445

High

1032182

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

18

High-throughput

0.445

High

1223639

ULK2
Serine/threonine-protein kinase ULK2

1

8

High-throughput

0.445

High

1255734

RBCC1
RB1-inducible coiled-coil protein 1

1

20

High-throughput

0.445

High

1345807

ECHD1
Ethylmalonyl-CoA decarboxylase

1

4

High-throughput

0.445

High

1354518

DNJB4
DnaJ homolog subfamily B member 4

1

11

High-throughput

0.445

High

1377894

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

1

18

High-throughput

0.445

High

1377895

MAGD1
Melanoma-associated antigen D1

1

9

High-throughput

0.445

High

654934

CALX
Calnexin

1

4

Small-scale

0.437

High

1172426

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.437

High

1189106

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.437

High

1344929

STRN4
Striatin-4

1

16

High-throughput

0.417

High

311305

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

1

High-throughput

0.407

High

373088

VTNC
Vitronectin

1

1

High-throughput

0.407

High

1287235

FAF2
FAS-associated factor 2

1

1

High-throughput

0.407

High

1310273

CAB45
45 kDa calcium-binding protein

1

6

High-throughput

0.407

High

1349260

HPBP1
Hsp70-binding protein 1

1

3

High-throughput

0.407

High

1355685

PRAF1
Prenylated Rab acceptor protein 1

3

0

High-throughput

0.352

High

225225

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

3

0

High-throughput

0.347

High

439198

SYPH
Synaptophysin

2

0

High-throughput

0.316

High

1169581

DG2L6
Diacylglycerol O-acyltransferase 2-like protein 6

2

0

High-throughput

0.316

High

1289044

RRFM
Ribosome-recycling factor, mitochondrial

2

0

High-throughput

0.316

High

1302897

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.279

Low

1377837

TCAF1
TRPM8 channel-associated factor 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024