Protein: SYB
Synaptobrevin

Gene: SYB
Organism: Drosophila melanogaster
Interactions: 119
UniProt ID: P18489

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0005484 - SNAP receptor activity
GO:0005886 - plasma membrane
GO:0006906 - vesicle fusion
GO:0007269 - neurotransmitter secretion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

614903

STX1A
Syntaxin-1A

6

20

Small-scale

0.930

High

614895

SNAP
Alpha-soluble NSF attachment protein

2

20

High-throughput

0.737

High

614896

SLY1
Protein sly1 homolog

2

20

High-throughput

0.737

High

614902

STX5
Syntaxin-5

2

20

High-throughput

0.737

High

614910

Q7JYX5
Vesicle-associated membrane protein 7

2

16

High-throughput

0.737

High

614911

Q7K0X9
LD23667p

2

20

High-throughput

0.737

High

614932

Q9U6R9
Gamma-soluble NSF attachment protein

2

20

High-throughput

0.737

High

614939

GOSR1
Golgi SNAP receptor complex member 1

2

14

High-throughput

0.737

High

614954

Q9VR90
Syntaxin 16

2

20

High-throughput

0.737

High

614955

GOSR2
Probable Golgi SNAP receptor complex member 2

2

20

High-throughput

0.737

High

614960

Q9VU45
LD27581p

2

20

High-throughput

0.737

High

614962

Q9VV76
Syntaxin 8

2

20

High-throughput

0.737

High

614963

Q9VVX6
BET1 homolog

2

20

High-throughput

0.737

High

614973

Q9W0N6
LD27967p

2

20

High-throughput

0.737

High

614978

Q9W3M8
LD34211p

2

18

High-throughput

0.737

High

614975

Q9W1I8
LD03592p

4

20

Small-scale

0.685

High

614942

Q9VH76
Synaptosomal-associated protein

3

20

High-throughput

0.654

High

121784

M9PGI6
Secretory 22, isoform B

1

17

High-throughput

0.618

High

614909

Q7JRF1
RE48509p

1

20

High-throughput

0.618

High

614913

STX4
Syntaxin-4

1

20

High-throughput

0.618

High

84843

B7Z0M0
FI17308p1

1

20

High-throughput

0.575

High

305552

O77434
EG:34F3.8 protein

1

17

High-throughput

0.575

High

233509

SPY
Protein sprouty

2

1

High-throughput

0.571

High

614926

FAXC
Failed axon connections

2

3

High-throughput

0.571

High

614950

Q9VNI9
IP18173p

2

6

High-throughput

0.571

High

614957

USE1
Vesicle transport protein USE1

2

8

High-throughput

0.571

High

614888

SNP25
Synaptosomal-associated protein 25

2

20

High-throughput

0.552

High

614916

Q8IPV3
Uncharacterized protein, isoform A

2

0

High-throughput

0.547

High

614938

Q9VBL3
GH01188p

1

1

High-throughput

0.541

High

614944

PICAL
Phosphatidylinositol-binding clathrin assembly protein LAP

1

1

High-throughput

0.541

High

614925

Q95R82
SD02746p

2

3

High-throughput

0.521

High

614951

Q9VNW1
DnaJ homolog subfamily B member 9

2

10

High-throughput

0.521

High

614961

FRL
Formin-like protein

2

3

High-throughput

0.521

High

614945

Q9VJ14
RING-type E3 ubiquitin transferase

1

0

High-throughput

0.517

High

53047

A1Z7K2
FI03455p

1

4

High-throughput

0.494

High

614882

GSTD1
Glutathione S-transferase D1

1

1

High-throughput

0.494

High

614890

TNNC2
Troponin C, isoform 2

1

1

High-throughput

0.494

High

119958

M9PBW9
Rhea, isoform G

1

2

High-throughput

0.481

High

614934

Q9V483
Unc-13, isoform C

1

2

High-throughput

0.481

High

117898

M9MRE1
PDGF- and VEGF-receptor related, isoform K

1

11

High-throughput

0.479

High

263595

FLOT2
Flotillin-2

1

2

High-throughput

0.479

High

614914

Q7KY04
small monomeric GTPase

1

20

High-throughput

0.479

High

614920

Q8MRA3
Hibris, isoform A

1

2

High-throughput

0.479

High

614927

Q95U21
receptor protein serine/threonine kinase

1

1

High-throughput

0.479

High

614971

DOS
Protein daughter of sevenless

1

2

High-throughput

0.479

High

614941

Q9VH54
GH24564p

1

0

High-throughput

0.458

High

614922

Q8T049
LD28927p

1

1

High-throughput

0.457

High

614956

Q9VSL8
Rhea, isoform B

1

2

High-throughput

0.457

High

74999

B3DND5
IP20181p

1

1

High-throughput

0.451

High

56146

A1Z9X4
Hibris, isoform B

1

1

High-throughput

0.445

High

355914

O96692
small monomeric GTPase

1

20

High-throughput

0.445

High

614881

GNAI
G protein alpha i subunit

1

2

High-throughput

0.445

High

614883

ANXB9
Annexin B9

1

1

High-throughput

0.445

High

614884

ANX10
Annexin B10

1

1

High-throughput

0.445

High

614893

MY31D
Unconventional myosin ID

1

2

High-throughput

0.445

High

614894

MY61F
Unconventional myosin IC

1

2

High-throughput

0.445

High

614897

STNB
Protein stoned-B

1

2

Small-scale

0.445

High

614904

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

4

High-throughput

0.445

High

614915

Q8IPG1
PDGF- and VEGF-receptor related, isoform B

1

11

High-throughput

0.445

High

614949

AK200
A-kinase anchor protein 200

1

7

High-throughput

0.445

High

614967

Q9VXV6
Secretory carrier-associated membrane protein

1

12

High-throughput

0.445

High

614905

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit 2

1

1

High-throughput

0.439

High

614969

Q9VZR1
Phosphatidylinositol glycan anchor biosynthesis class C, isoform B

1

1

High-throughput

0.439

High

50249

A1A714
IP17403p

1

1

High-throughput

0.437

High

52636

A1Z729
NADP-retinol dehydrogenase

1

2

High-throughput

0.437

High

53414

A1Z7S0
Receptor mediated endocytosis 8, isoform A

1

8

High-throughput

0.437

High

614940

Q9VE72
Cyclin-Q

1

2

High-throughput

0.437

High

614931

ORAI1
Calcium release-activated calcium channel protein 1

1

0

High-throughput

0.426

High

614921

Q8MRQ5
GH05455p

1

2

High-throughput

0.417

High

614966

PP2B3
Serine/threonine-protein phosphatase 2B catalytic subunit 3

1

1

High-throughput

0.417

High

614970

Q9VZU6
BTB-VII protein domain

1

2

High-throughput

0.417

High

57514

A1ZB71
Glutathione S transferase E6

1

1

High-throughput

0.407

High

121172

ALDR
Aldo-keto reductase 1B

1

1

High-throughput

0.407

High

614885

PHB1
Prohibitin 1

1

2

High-throughput

0.407

High

614889

SEPT1
Septin-1

1

3

High-throughput

0.407

High

614891

SEPT2
Septin-2

1

3

High-throughput

0.407

High

614912

Q7K110
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

3

High-throughput

0.407

High

614917

Q8IQZ7
FI19014p1

1

1

High-throughput

0.407

High

614918

Q8IRD3
Glutathione peroxidase

1

5

High-throughput

0.407

High

614928

Q960C7
NADP-retinol dehydrogenase

1

2

High-throughput

0.407

High

614929

Q960F6
SD03655p

1

1

High-throughput

0.407

High

614936

CISD2
CDGSH iron-sulfur domain protein

1

1

High-throughput

0.407

High

614943

TEBPH
Cytosolic Prostaglandin E synthase

1

3

High-throughput

0.407

High

614947

Q9VKW5
Prolyl endopeptidase

1

2

High-throughput

0.407

High

614953

Q9VPN5
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.407

High

614958

Q9VTY2
Uncharacterized protein, isoform A

1

1

High-throughput

0.407

High

614968

Q9VZI1
Transgelin

1

1

High-throughput

0.407

High

614972

Q9W0H8
Reticulocalbin-3

1

2

High-throughput

0.407

High

614977

Q9W323
Tyrosine-protein phosphatase non-receptor type 9

1

4

High-throughput

0.407

High

614900

ATP5J
ATP synthase-coupling factor 6, mitochondrial

2

0

High-throughput

0.298

High

614907

Q4QQB9
LP21121p

2

0

High-throughput

0.298

High

614924

VDAC
Voltage-dependent anion-selective channel

2

0

High-throughput

0.298

High

614937

Q9VBF0
Ras modification protein ERF4

2

0

High-throughput

0.298

High

614965

Q9VW70
FI21813p1

2

0

High-throughput

0.298

High

614952

Q9VPI9
LD20667p

1

0

High-throughput

0.282

High

304921

CRY1
Cryptochrome-1

1

0

High-throughput

0.249

Low

559123

ELF1
Protein grainyhead

1

0

High-throughput

0.249

Low

614892

Q1ECB1
Membrane protein BRI3

1

0

High-throughput

0.249

Low

614906

Q2QBM1
Malic enzyme

1

0

High-throughput

0.249

Low

614919

Q8MLQ0
FI14118p

1

0

High-throughput

0.249

Low

53965

A1Z892
1-Cys peroxiredoxin

1

0

High-throughput

0.232

Low

357248

O97428
Ciboulot, isoform A

1

0

High-throughput

0.232

Low

614886

PROF
Profilin

1

0

High-throughput

0.232

Low

614887

UCHL
Ubiquitin carboxyl-terminal hydrolase

1

0

High-throughput

0.232

Low

614898

ATP5H
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.232

Low

614899

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.232

Low

614901

ATPO
ATP synthase subunit O, mitochondrial

1

0

High-throughput

0.232

Low

614908

Q7JR58
Probable enoyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.232

Low

614923

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.232

Low

614930

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

1

0

High-throughput

0.232

Low

614933

KRH2
Krueppel homolog 2

1

0

High-throughput

0.232

Low

614935

CYB5
Cytochrome b5

1

0

High-throughput

0.232

Low

614946

Q9VKM7
AT01533p

1

0

High-throughput

0.232

Low

614948

EF1D
Probable elongation factor 1-delta

1

0

High-throughput

0.232

Low

614959

Q9VU35
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.232

Low

614964

Q9VW59
Rho GDP-dissociation inhibitor 3

1

0

High-throughput

0.232

Low

614974

ATPK
Putative ATP synthase subunit f, mitochondrial

1

0

High-throughput

0.232

Low

614976

Q9W227
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.232

Low

614979

Q9W3Y3
Calcyclin-binding protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025