Protein: MDR1
ATP-dependent translocase ABCB1 (ATP-binding cassette sub-family B member 1) (Multidrug resistance protein 1) (EC 7.6.2.2) (P-glycoprotein 1) (Phospholipid transporter ABCB1) (EC 7.6.2.1) (CD antigen CD243)

Gene: MDR1, ABCB1
Organism: Homo sapiens
Interactions: 51
UniProt ID: P08183

Gene Ontology (top 5):
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006805 - xenobiotic metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

437179

LEG3
Galectin-3

3

10

High-throughput

0.667

High

437187

RB11A
Ras-related protein Rab-11A

2

1

High-throughput

0.611

High

437177

PIM1
Serine/threonine-protein kinase pim-1

1

0

Small-scale

0.554

High

437185

CCR6
C-C chemokine receptor type 6

1

5

High-throughput

0.536

High

437196

TTMP
TPA-induced transmembrane protein

1

2

High-throughput

0.536

High

437204

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

2

High-throughput

0.536

High

437212

TTYH1
Protein tweety homolog 1

1

2

High-throughput

0.536

High

437216

EDAR
Tumor necrosis factor receptor superfamily member EDAR

1

2

High-throughput

0.536

High

353242

CD4
T-cell surface glycoprotein CD4

1

0

High-throughput

0.518

High

437210

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

0

High-throughput

0.518

High

437176

BCL2
Apoptosis regulator Bcl-2

1

0

High-throughput

0.513

High

437181

CALX
Calnexin

1

0

High-throughput

0.513

High

437186

T2R19
Taste receptor type 2 member 19

1

0

High-throughput

0.513

High

437201

ARRD4
Arrestin domain-containing protein 4

1

0

High-throughput

0.513

High

437207

TM169
Transmembrane protein 169

1

0

High-throughput

0.513

High

437208

RING2
E3 ubiquitin-protein ligase RING2

1

1

Small-scale

0.506

High

434900

SP1
Transcription factor Sp1

1

1

Small-scale

0.501

High

259547

HMMR
Hyaluronan mediated motility receptor

1

0

High-throughput

0.493

High

437194

LEG9B
Galectin-9B

1

10

High-throughput

0.489

High

437206

SAAL1
Protein SAAL1

1

1

High-throughput

0.489

High

437182

PSB8
Proteasome subunit beta type-8

1

1

Small-scale

0.481

High

437203

LNX1
E3 ubiquitin-protein ligase LNX

1

2

Small-scale

0.481

High

437184

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

Small-scale

0.480

High

119094

LEG9
Galectin-9

1

10

High-throughput

0.479

High

349809

RASK
GTPase KRas

1

7

High-throughput

0.479

High

384119

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.479

High

437175

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

5

Small-scale

0.479

High

437178

RHOQ
Rho-related GTP-binding protein RhoQ

1

12

High-throughput

0.479

High

437189

CAV1
Caveolin-1

1

2

Small-scale

0.479

High

437197

MARH8
E3 ubiquitin-protein ligase MARCHF8

1

2

Small-scale

0.479

High

437198

RHOU
Rho-related GTP-binding protein RhoU

1

16

High-throughput

0.479

High

437209

PHB2
Prohibitin-2

1

2

High-throughput

0.479

High

437211

CP250
Centrosome-associated protein CEP250

1

1

High-throughput

0.479

High

437217

LAMP3
Lysosome-associated membrane glycoprotein 3

1

3

High-throughput

0.479

High

437183

UBA7
Ubiquitin-like modifier-activating enzyme 7

1

0

Small-scale

0.458

High

437190

DHX9
ATP-dependent RNA helicase A

1

0

Small-scale

0.458

High

437192

CUL7
Cullin-7

1

0

High-throughput

0.458

High

437195

MIDN
Midnolin

1

0

High-throughput

0.458

High

437199

LAP4B
Lysosomal-associated transmembrane protein 4B

1

0

Small-scale

0.458

High

437214

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.458

High

437188

SP3
Transcription factor Sp3

1

1

Small-scale

0.457

High

345726

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.445

High

437180

CD9
CD9 antigen

1

2

High-throughput

0.445

High

437202

FXL13
F-box and leucine-rich repeat protein 13

1

1

Small-scale

0.437

High

437215

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.437

High

393955

A4
Amyloid-beta precursor protein

1

0

Small-scale

0.426

High

437205

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

Small-scale

0.301

High

437213

BCCIP
BRCA2 and CDKN1A-interacting protein

1

0

High-throughput

0.282

High

437193

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

Small-scale

0.251

Low

437191

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.249

Low

437200

FBX15
F-box only protein 15

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024