Protein: SC11A
Signal peptidase complex catalytic subunit SEC11A (EC 3.4.21.89) (Endopeptidase SP18) (Microsomal signal peptidase 18 kDa subunit) (SPase 18 kDa subunit) (SEC11 homolog A) (SEC11-like protein 1) (SPC18)

Gene: SC11A, SEC11A
Organism: Homo sapiens
Interactions: 93
UniProt ID: P67812

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005787 - signal peptidase complex
GO:0005789 - endoplasmic reticulum membrane
GO:0006465 - signal peptide processing
GO:0008233 - peptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

931515

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

2

3

High-throughput

0.558

High

931565

FBX6
F-box only protein 6

2

1

High-throughput

0.558

High

621775

PRTN3
Myeloblastin

1

2

High-throughput

0.536

High

894842

SPCS3
Signal peptidase complex subunit 3

1

2

High-throughput

0.536

High

931523

SPCS2
Signal peptidase complex subunit 2

1

2

High-throughput

0.536

High

931530

TGO1
Transport and Golgi organization protein 1 homolog

1

1

High-throughput

0.536

High

931549

NCLN
BOS complex subunit NCLN

1

1

High-throughput

0.536

High

931550

CCD47
PAT complex subunit CCDC47

1

1

High-throughput

0.536

High

931568

VAPA
Vesicle-associated membrane protein-associated protein A

1

2

High-throughput

0.536

High

931573

SPCS1
Signal peptidase complex subunit 1

1

3

High-throughput

0.536

High

207554

RNF13
E3 ubiquitin-protein ligase RNF13

1

0

High-throughput

0.513

High

654248

CALX
Calnexin

1

0

High-throughput

0.513

High

931518

UPAR
Urokinase plasminogen activator surface receptor

1

0

High-throughput

0.513

High

125992

UPK1A
Uroplakin-1a

1

1

High-throughput

0.489

High

310272

LYPD3
Ly6/PLAUR domain-containing protein 3

1

1

High-throughput

0.489

High

824912

DNSL1
Deoxyribonuclease-1-like 1

1

1

High-throughput

0.489

High

931524

AMHR2
Anti-Muellerian hormone type-2 receptor

1

1

High-throughput

0.489

High

931528

ZACN
Ligand-gated cation channel ZACN

1

4

High-throughput

0.489

High

931539

FXL14
F-box/LRR-repeat protein 14

1

1

High-throughput

0.489

High

931561

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.489

High

931570

FBX2
F-box only protein 2

1

1

High-throughput

0.489

High

931571

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

3

High-throughput

0.489

High

931574

WNT6
Protein Wnt-6

1

1

High-throughput

0.489

High

893886

CDC42
Cell division control protein 42 homolog

1

2

High-throughput

0.479

High

900363

RHOA
Transforming protein RhoA

1

3

High-throughput

0.479

High

931517

RHOG
Rho-related GTP-binding protein RhoG

1

2

High-throughput

0.479

High

931544

RBCC1
RB1-inducible coiled-coil protein 1

1

1

High-throughput

0.479

High

931519

Q08AM2
ADAM33 protein

1

3

High-throughput

0.470

High

931529

MKS3
Meckelin

1

0

High-throughput

0.458

High

931534

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

931542

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

931551

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

931553

MIA2
Melanoma inhibitory activity protein 2

1

2

High-throughput

0.445

High

931540

S35F6
Solute carrier family 35 member F6

1

1

High-throughput

0.439

High

931559

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

1

3

High-throughput

0.439

High

120381

RHOD
Rho-related GTP-binding protein RhoD

1

4

High-throughput

0.437

High

377237

GCR
Glucocorticoid receptor

1

1

High-throughput

0.437

High

931527

TECT1
Tectonic-1

1

3

High-throughput

0.437

High

931533

TECT3
Tectonic-3

1

3

High-throughput

0.437

High

931546

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

931552

TECT2
Tectonic-2

1

3

High-throughput

0.437

High

931558

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.437

High

931562

RHOF
Rho-related GTP-binding protein RhoF

1

4

High-throughput

0.437

High

931531

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

714815

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

2

0

High-throughput

0.328

High

413034

CHLE
Cholinesterase

2

0

High-throughput

0.316

High

233361

NUPR1
Nuclear protein 1

2

0

Small-scale

0.300

High

606873

IDS
Iduronate 2-sulfatase

1

0

High-throughput

0.279

Low

644706

NKG2D
NKG2-D type II integral membrane protein

1

0

High-throughput

0.279

Low

686633

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.279

Low

847746

P2RX1
P2X purinoceptor 1

1

0

High-throughput

0.279

Low

905504

TSN5
Tetraspanin-5

1

0

High-throughput

0.279

Low

931516

ASIC1
Acid-sensing ion channel 1

1

0

High-throughput

0.279

Low

931520

SIAT6
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase

1

0

High-throughput

0.279

Low

931532

PVRIG
Transmembrane protein PVRIG

1

0

High-throughput

0.279

Low

931536

GOGA7
Golgin subfamily A member 7

1

0

High-throughput

0.279

Low

931543

LPD6B
Ly6/PLAUR domain-containing protein 6B

1

0

High-throughput

0.279

Low

931545

SSMM1
Serine-rich single-pass membrane protein 1

1

0

High-throughput

0.279

Low

931555

DNJC2
DnaJ homolog subfamily C member 2

1

0

High-throughput

0.279

Low

931556

TM2D3
TM2 domain-containing protein 3

1

0

High-throughput

0.279

Low

931560

RTN4R
Reticulon-4 receptor

1

0

High-throughput

0.279

Low

931563

TREM1
Triggering receptor expressed on myeloid cells 1

1

0

High-throughput

0.279

Low

931525

H31T
Histone H3.1t

1

0

High-throughput

0.269

Low

931548

TNR14
Tumor necrosis factor receptor superfamily member 14

1

0

High-throughput

0.269

Low

931513

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.251

Low

119325

LEG9
Galectin-9

1

0

High-throughput

0.249

Low

148660

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

205256

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

239564

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.249

Low

354415

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.249

Low

506962

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.249

Low

531788

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.249

Low

601207

VDAC1
Voltage-dependent anion-selective channel protein 1

1

0

High-throughput

0.249

Low

832348

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.249

Low

897502

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.249

Low

908339

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

912841

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.249

Low

931514

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

931521

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.249

Low

931522

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

931526

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.249

Low

931535

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

931537

LBN
Limbin

1

0

High-throughput

0.249

Low

931538

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

931547

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

0

High-throughput

0.249

Low

931554

RING2
E3 ubiquitin-protein ligase RING2

1

0

High-throughput

0.249

Low

931557

OVOL2
Transcription factor Ovo-like 2

1

0

Small-scale

0.249

Low

931564

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low

931566

T106B
Transmembrane protein 106B

1

0

High-throughput

0.249

Low

931567

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

931569

TM216
Transmembrane protein 216

1

0

High-throughput

0.249

Low

931572

TRAF6
TNF receptor-associated factor 6

1

0

High-throughput

0.249

Low

931541

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024