Protein: GPRK2
G protein-coupled receptor kinase 2 (EC 2.7.11.16)

Gene: GPRK2
Organism: Drosophila melanogaster
Interactions: 50
UniProt ID: P32866

Gene Ontology (top 5):
GO:0003384 - apical constriction involved in gastrulation
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004703 - G protein-coupled receptor kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

746376

GPRK2
G protein-coupled receptor kinase 2

1

17

Small-scale

0.724

High

746380

SMO
Protein smoothened

2

1

Small-scale

0.634

High

661841

FUSED
Serine/threonine-protein kinase fused

1

19

Small-scale

0.618

High

746381

CACT
NF-kappa-B inhibitor cactus

1

11

Small-scale

0.618

High

746414

DDB1
DNA damage-binding protein 1

1

7

Small-scale

0.618

High

746377

SQH
Myosin regulatory light chain sqh

1

4

High-throughput

0.575

High

746415

Q9Y128
Ceramide transfer protein

1

5

High-throughput

0.575

High

746384

Q5BI62
ABC-type xenobiotic transporter

1

0

High-throughput

0.546

High

746378

CANB1
Calcineurin subunit B type 1

1

5

High-throughput

0.514

High

746386

Q7K012
Brahma associated protein 55kD

1

13

High-throughput

0.514

High

746389

Q8MLQ3
Uncharacterized protein, isoform C

1

4

High-throughput

0.514

High

746387

Q7YTZ4
GH22187p

1

0

High-throughput

0.481

High

746402

Q9VM00
Rap GTPase activating protein 1, isoform D

1

3

High-throughput

0.481

High

684597

GBB1
Guanine nucleotide-binding protein subunit beta-1

1

9

Small-scale

0.479

High

715328

GBB2
Guanine nucleotide-binding protein subunit beta-2

1

10

Small-scale

0.479

High

746383

Q5BI50
Cullin-4A

1

8

Small-scale

0.479

High

746392

SMUF1
E3 ubiquitin-protein ligase Smurf1

1

20

Small-scale

0.479

High

746403

Q9VM02
Rap GTPase activating protein 1, isoform E

1

3

High-throughput

0.457

High

84630

B7Z043
Myocardin-related transcription factor, isoform H

1

1

High-throughput

0.445

High

583627

TOP2
DNA topoisomerase 2

1

6

High-throughput

0.445

High

746379

TCPG
T-complex protein 1 subunit gamma

1

14

High-throughput

0.445

High

746390

Q8SXM8
Lysine--tRNA ligase

1

2

High-throughput

0.445

High

746395

LARP
La-related protein 1

1

7

High-throughput

0.445

High

746401

Q9VK69
T-complex protein 1 subunit delta

1

20

High-throughput

0.445

High

746404

Q9VQR8
leucine--tRNA ligase

1

2

High-throughput

0.445

High

746409

JARD2
Jumonji, AT rich interactive domain protein 2

1

2

High-throughput

0.445

High

746412

Q9W2Z4
DNA replication ATP-dependent helicase/nuclease

1

1

High-throughput

0.445

High

746413

Q9W392
T-complex protein 1 subunit beta

1

20

High-throughput

0.445

High

746385

Q7JVY2
Double parked, isoform A

1

0

High-throughput

0.426

High

746405

ELP3
Elongator complex protein 3

1

0

High-throughput

0.426

High

196107

HIRA
Protein HIRA homolog

1

3

High-throughput

0.407

High

710927

RS6
Small ribosomal subunit protein eS6

1

9

High-throughput

0.407

High

746391

GLYR1
Cytokine-like nuclear factor N-PAC

1

3

High-throughput

0.407

High

746393

Q9VA59
Tropomodulin, isoform D

1

1

High-throughput

0.407

High

746396

Q9VGN4
Sarcomere length short, isoform B

1

6

High-throughput

0.407

High

746398

RM13
Large ribosomal subunit protein uL13m

1

1

High-throughput

0.407

High

746399

CL190
Restin homolog

1

14

High-throughput

0.407

High

746400

Q9VK08
Uncharacterized protein, isoform P

1

12

High-throughput

0.407

High

746406

S35E1
Solute carrier family 35 member E1 homolog

1

1

High-throughput

0.407

High

746410

POMT1
Protein O-mannosyltransferase 1

1

1

High-throughput

0.407

High

746411

Q9VTN6
Twitchy

1

15

High-throughput

0.407

High

746416

Q9Y141
Carboxylic ester hydrolase

1

1

High-throughput

0.407

High

51882

A1Z6H6
Peptidase M3A/M3B catalytic domain-containing protein

1

0

High-throughput

0.232

Low

746382

ELP5
Elongator complex protein 5

1

0

High-throughput

0.232

Low

746388

Q8ING1
Uncharacterized protein

1

0

High-throughput

0.232

Low

746394

PTC71
Protein phosphatase PTC7 homolog fig

1

0

High-throughput

0.232

Low

746397

NDUF7
Protein arginine methyltransferase NDUFAF7 homolog, mitochondrial

1

0

High-throughput

0.232

Low

746407

Q9VR65
Uncharacterized protein

1

0

High-throughput

0.232

Low

746408

ATAT1
Alpha-tubulin N-acetyltransferase 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025