Protein: ATP7A
Copper-transporting ATPase 1 (EC 7.2.2.8) (Copper pump 1) (Menkes disease-associated protein)

Gene: ATP7A
Organism: Homo sapiens
Interactions: 89
UniProt ID: Q04656

Gene Ontology (top 5):
GO:0001568 - blood vessel development
GO:0001701 - in utero embryonic development
GO:0001889 - liver development
GO:0001974 - blood vessel remodeling
GO:0002082 - regulation of oxidative phosphorylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

122325

ATOX1
Copper transport protein ATOX1

2

6

Small-scale

0.786

High

980116

APBB2
Amyloid beta precursor protein binding family B member 2

3

2

High-throughput

0.667

High

160918

RAB7L
Ras-related protein Rab-7L1

2

8

High-throughput

0.628

High

212286

ITM2A
Integral membrane protein 2A

2

7

High-throughput

0.628

High

964102

CD83
CD83 antigen

2

1

High-throughput

0.628

High

980101

C3AR
C3a anaphylatoxin chemotactic receptor

2

13

High-throughput

0.628

High

980106

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

2

7

High-throughput

0.628

High

980129

CLC2D
C-type lectin domain family 2 member D

2

7

High-throughput

0.628

High

636477

DNJB2
DnaJ homolog subfamily B member 2

2

1

High-throughput

0.611

High

788819

RS27
Small ribosomal subunit protein eS27

2

1

High-throughput

0.611

High

980134

LAMP3
Lysosome-associated membrane glycoprotein 3

2

8

High-throughput

0.611

High

980133

COG5
Conserved oligomeric Golgi complex subunit 5

2

0

High-throughput

0.602

High

980135

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.602

High

350098

RASK
GTPase KRas

2

11

High-throughput

0.584

High

915623

RHOB
Rho-related GTP-binding protein RhoB

2

15

High-throughput

0.584

High

980104

PDZ11
PDZ domain-containing protein 11

1

0

Small-scale

0.564

High

728540

GLRX1
Glutaredoxin-1

1

2

Small-scale

0.552

High

456855

FURIN
Furin

1

1

High-throughput

0.536

High

666308

NK3R
Neuromedin-K receptor

1

6

High-throughput

0.536

High

861708

PLK1
Serine/threonine-protein kinase PLK1

1

3

High-throughput

0.536

High

862288

NUBP1
Cytosolic Fe-S cluster assembly factor NUBP1

1

1

High-throughput

0.536

High

943971

X3CL1
Fractalkine

1

2

High-throughput

0.536

High

980094

FOXF2
Forkhead box protein F2

1

2

High-throughput

0.536

High

980095

KLRD1
Natural killer cells antigen CD94

1

7

High-throughput

0.536

High

980100

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

1

High-throughput

0.536

High

980115

HUMMR
Protein MGARP

1

1

High-throughput

0.536

High

980118

ORAI1
Calcium release-activated calcium channel protein 1

1

1

High-throughput

0.536

High

980121

IFT27
Intraflagellar transport protein 27 homolog

1

6

High-throughput

0.536

High

980123

SEM4C
Semaphorin-4C

1

1

High-throughput

0.536

High

980125

CHODL
Chondrolectin

1

1

High-throughput

0.536

High

980128

HCST
Hematopoietic cell signal transducer

1

1

High-throughput

0.536

High

980130

KLK12
Kallikrein-12

1

2

High-throughput

0.536

High

980131

TSN16
Tetraspanin-16

1

10

High-throughput

0.536

High

980137

PCDGD
Protocadherin gamma-B1

1

9

High-throughput

0.536

High

980096

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

2

High-throughput

0.515

High

380372

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

High-throughput

0.513

High

980108

CK087
Uncharacterized protein C11orf87

1

0

High-throughput

0.513

High

980112

TM130
Transmembrane protein 130

1

0

High-throughput

0.513

High

980122

TMM59
Transmembrane protein 59

1

0

High-throughput

0.513

High

980136

O10H1
Olfactory receptor 10H1

1

0

High-throughput

0.513

High

980097

LAGE3
EKC/KEOPS complex subunit LAGE3

1

2

High-throughput

0.489

High

448124

DOPO
Dopamine beta-hydroxylase

1

0

Small-scale

0.479

High

119339

LEG9
Galectin-9

1

2

High-throughput

0.479

High

178496

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

205298

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

318114

DIRA3
GTP-binding protein Di-Ras3

1

3

High-throughput

0.479

High

348628

RASN
GTPase NRas

1

11

High-throughput

0.479

High

349262

RASH
GTPase HRas

1

7

High-throughput

0.479

High

384687

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.479

High

433714

LYN
Tyrosine-protein kinase Lyn

1

3

High-throughput

0.479

High

436266

RHOC
Rho-related GTP-binding protein RhoC

1

13

High-throughput

0.479

High

500774

CLUS
Clusterin

1

2

Small-scale

0.479

High

506979

LAMP1
Lysosome-associated membrane glycoprotein 1

1

8

High-throughput

0.479

High

527411

LAMP2
Lysosome-associated membrane glycoprotein 2

1

8

High-throughput

0.479

High

544960

AMPN
Aminopeptidase N

1

1

High-throughput

0.479

High

567021

CXA1
Gap junction alpha-1 protein

1

7

High-throughput

0.479

High

591821

RAB4A
Ras-related protein Rab-4A

1

5

High-throughput

0.479

High

648733

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.479

High

729642

VGFR2
Vascular endothelial growth factor receptor 2

1

1

Small-scale

0.479

High

793284

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.479

High

844492

RAB5C
Ras-related protein Rab-5C

1

4

High-throughput

0.479

High

844887

RAB7A
Ras-related protein Rab-7a

1

8

High-throughput

0.479

High

892330

RAC3
Ras-related C3 botulinum toxin substrate 3

1

13

High-throughput

0.479

High

895049

RAB2A
Ras-related protein Rab-2A

1

6

High-throughput

0.479

High

900402

RHOA
Transforming protein RhoA

1

14

High-throughput

0.479

High

925218

RAC1
Ras-related C3 botulinum toxin substrate 1

1

13

High-throughput

0.479

High

980099

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.479

High

980102

OCLN
Occludin

1

1

High-throughput

0.479

High

980107

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.479

High

980109

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.479

High

980111

CXD3
Gap junction delta-3 protein

1

7

High-throughput

0.479

High

980113

COMD1
COMM domain-containing protein 1

1

1

Small-scale

0.479

High

980114

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.479

High

980120

SNX27
Sorting nexin-27

1

6

Small-scale

0.479

High

980124

DNJC5
DnaJ homolog subfamily C member 5

1

2

High-throughput

0.479

High

980126

RHOF
Rho-related GTP-binding protein RhoF

1

17

High-throughput

0.479

High

980138

ARL5A
ADP-ribosylation factor-like protein 5A

1

3

High-throughput

0.479

High

980098

T132D
Transmembrane protein 132D

1

0

Small-scale

0.460

High

602247

CD9
CD9 antigen

1

5

High-throughput

0.445

High

980110

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

980117

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

980127

ARL15
ADP-ribosylation factor-like protein 15

1

5

High-throughput

0.437

High

209230

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.426

High

353926

IGHM
Immunoglobulin heavy constant mu

1

0

High-throughput

0.426

High

980119

DTBP1
Dysbindin

1

0

Small-scale

0.426

High

980132

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

1

0

Small-scale

0.426

High

854414

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

0

High-throughput

0.279

Low

980105

LY65C
Lymphocyte antigen 6 complex locus protein G5c

1

0

High-throughput

0.279

Low

980103

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024