HitPredict - High confidence protein-protein interactions

Interactor 1: KCNK1 (O00180)
Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel K2P1) (Potassium channel KCNO1)
Gene: KCNK1

Interactor 2: KCNK1 (O00180)
Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel K2P1) (Potassium channel KCNO1)
Gene: KCNK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	8978667, 22282804
Identification Methods	pull down, x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ion_trans_2~Ion_trans_2
Common GO terms	GO:0005242 - inward rectifier potassium channel activity GO:0005267 - potassium channel activity GO:0005272 - sodium channel activity GO:0005886 - plasma membrane GO:0006813 - potassium ion transport and 18 others more... GO:0008076 - voltage-gated potassium channel complex GO:0015271 - outward rectifier potassium channel activity GO:0016020 - membrane GO:0016324 - apical plasma membrane GO:0022841 - potassium ion leak channel activity GO:0030322 - stabilization of membrane potential GO:0030425 - dendrite GO:0031526 - brush border membrane GO:0034705 - potassium channel complex GO:0035094 - response to nicotine GO:0035725 - sodium ion transmembrane transport GO:0043204 - perikaryon GO:0043231 - intracellular membrane-bounded organelle GO:0055037 - recycling endosome GO:0060075 - regulation of resting membrane potential GO:0071805 - potassium ion transmembrane transport GO:0097060 - synaptic membrane GO:1902937 - inward rectifier potassium channel complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	336
Hs

1	336

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Last updated: 15 Jul 2024