Protein: HIW
E3 ubiquitin-protein ligase highwire (EC 2.3.2.33) (Protein pam/highwire/rpm-1)

Gene: HIW
Organism: Drosophila melanogaster
Interactions: 10
UniProt ID: Q9NB71

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0006914 - autophagy
GO:0007411 - axon guidance
GO:0007616 - long-term memory

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1445290

RAE1
Protein Rae1

1

10

Small-scale

0.618

High

1445288

FBSP1
F-box/SPRY domain-containing protein 1

2

17

Small-scale

0.584

High

1445289

EXOC2
Exocyst complex component 2

1

0

High-throughput

0.518

High

305498

O77430
GEO01111p1

1

8

Small-scale

0.479

High

615088

PTC
Protein patched

1

0

High-throughput

0.460

High

1174597

TBB1
Tubulin beta-1 chain

1

9

Small-scale

0.437

High

1304757

Q8IPU8
BNIP3, isoform B

1

0

High-throughput

0.426

High

1377120

Q95R37
SD10969p

1

10

High-throughput

0.417

High

118985

M9NFI9
Neurabin-1

1

7

High-throughput

0.407

High

1302714

Q8IGE8
RH36596p

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025