Protein: MASP2
Mannan-binding lectin serine protease 2 (EC 3.4.21.104) (MBL-associated serine protease 2) (Mannose-binding protein-associated serine protease 2) (MASP-2) [Cleaved into: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain]

Gene: MASP2
Organism: Homo sapiens
Interactions: 19
UniProt ID: O00187

Gene Ontology (top 5):
GO:0001855 - complement component C4b binding
GO:0001867 - complement activation, lectin pathway
GO:0004252 - serine-type endopeptidase activity
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

119676

MASP2
Mannan-binding lectin serine protease 2

5

15

Small-scale

0.928

High

119683

CO4A
Complement C4-A

4

8

Small-scale

0.882

High

119684

CO4B
Complement C4-B

3

8

Small-scale

0.840

High

119686

MASP1
Mannan-binding lectin serine protease 1

2

15

Small-scale

0.789

High

119685

MBL2
Mannose-binding protein C

7

10

Small-scale

0.744

High

119688

FCN2
Ficolin-2

3

11

Small-scale

0.655

High

119680

CO3
Complement C3

1

8

Small-scale

0.647

High

119681

IC1
Plasma protease C1 inhibitor

1

20

Small-scale

0.647

High

119682

CO2
Complement C2

1

16

Small-scale

0.647

High

119689

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.553

High

119677

FCN1
Ficolin-1

1

11

Small-scale

0.515

High

119690

COL11
Collectin-11

1

8

Small-scale

0.515

High

119679

FCN3
Ficolin-3

1

11

Small-scale

0.501

High

119693

COL10
Collectin-10

1

8

Small-scale

0.479

High

119678

PITX3
Pituitary homeobox 3

1

5

Small-scale

0.437

High

119687

EP300
Histone acetyltransferase p300

1

1

High-throughput

0.437

High

119691

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.437

High

119692

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024